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Santa Cruz

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Santa Cruz Flights as Low as $426

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Cheap Flights to Santa Cruz

Fall in love at first flight with your vacation to Santa Cruz by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Cruz on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Cruz, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Cruz

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Cruz with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the null airport.

What is the cheapest month to fly to Santa Cruz?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Cruz are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Cruz?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Cruz.

What airport is best to fly into Santa Cruz?

When you’re planning your trip to Santa Cruz, convenience is the name of the game. Luckily, Santa Cruz Enrique Malek Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santa Cruz must-do list.

How much are flights to Santa Cruz?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Cruz on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $426, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Cruz?

The trick to saving a stack of cash on your flight to Santa Cruz? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $426 right now, why wait?

Santa Cruz Flight Information
Destination airport
Enrique Malek Intl.
Destination airport IATA code
DAV
Roundtrip price
$426

Last Minute Hotel Deals in Santa Cruz

Bocas del Mar Hotel

Bocas del Mar Hotel

4 out of 5
Road to Boca Chica Boca Chica Chiriqui
Book a stay at this family-friendly hotel in Boca Chica. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.6/10 Exceptional! (236 reviews)
"Excellent in every way! Room was beautiful and comfortable. The staff was wonderful."

Reviewed on Jul 20, 2026

Bocas del Mar Hotel
Seagull Cove Resort

Seagull Cove Resort

3.5 out of 5
Calle Principal Boca Chica Chiriqui
Stay at this hotel in Boca Chica. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.6/10 Exceptional! (100 reviews)
"Beautiful property that is surrounded by the jungle. The cove is gorgeous and we heard monkeys, saw roads and tree frogs and so many different types of birds. Dinner and breakfast were great and there was something for everyone in my family."

Reviewed on Jul 22, 2026

Seagull Cove Resort
Las Lajas Beach Resort

Las Lajas Beach Resort

3 out of 5
Playa Las Lajas Las Lajas Chiriqui
Book a stay at this beach hotel in Las Lajas. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (138 reviews)
"Great place for a beach stay in Panama. We loved the resort,the staff,the beach. Keep in mind this is a more rustic area,but the value here is terrific. We really enjoyed it. Also food and drinks are very reasonably priced,and very good."

Reviewed on Mar 26, 2025

Las Lajas Beach Resort
El Regalo Resort

El Regalo Resort

3.5 out of 5
RB048 Calle Syah Johan Boca Chica Chiriqui
Book a stay at this beach hotel in Boca Chica. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Playa Grande is located nearby.
9.8/10 Exceptional! (23 reviews)
"Food was really good, bed very confortable and nice quiet place"

Reviewed on Aug 10, 2025

El Regalo Resort
Country Hills Las Lajas

Country Hills Las Lajas

3 out of 5
Calle Principal a Las Lajas de San Felix San Felix Chiriquí Province
Stay at this hotel in San Félix. Enjoy free WiFi, free parking, and breakfast (surcharge).
7/10 Good! (2 reviews)
"Very private and comfortable place. The staff was excellent. Enjoyed staying there"

Reviewed on May 16, 2026

Country Hills Las Lajas
Show Pony Ranchero Resort - Boutique Beach Hotel

Show Pony Ranchero Resort - Boutique Beach Hotel

3 out of 5
Jobo Las Lajas Chiriqui
Book a stay at this beach hotel in Las Lajas. Enjoy free WiFi, free parking, and a private beach. Popular attraction Playa Las Lajas is located nearby.
Show Pony Ranchero Resort - Boutique Beach Hotel
Boca Chica Bay Eco Lodge

Boca Chica Bay Eco Lodge

3 out of 5
Avenida Gone Fishing Boca Chica Chiriqui
Book a stay at this business-friendly hotel in Boca Chica. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Boca Chica Marina and Playa ...
10/10 Exceptional! (55 reviews)
"Boca chica bay Eco Lodge have the best view ever! It is a great place to start the day before going out or the bay with amazing home cooked breakfast and great place to return and relax. The hosts are super nice and helpful."

Reviewed on Apr 19, 2026

Boca Chica Bay Eco Lodge
Hotel Los Troncos

Hotel Los Troncos

2.5 out of 5
Las Lajas Las Lajas Chiriqui
Book a stay at this business-friendly hotel in Las Lajas. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Playa Las Lajas is located ...
6.8/10 (3 reviews)
"Good location. Friendly Panamian Staff."

Reviewed on Jun 11, 2026

Hotel Los Troncos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.