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Santa Cruz Vacation Packages

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Santa Cruz
Chiriquí Province
Panama
Mexico and Central America
Hotwire.com

Santa Cruz Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Mahogany Suites

2 out of 5

Price was $1,003, price is now $510 per person

$510

per person

Apr 6 - Apr 10

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this golf hotel in Arraijan. Enjoy free WiFi, a golf course, and an outdoor pool. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

Central Hotel Panama Casco Viejo

4 out of 5

Save 100% on your flight

Price was $1,289, price is now $780 per person

$780

per person

Apr 6 - Apr 10

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Villa Botero By Casa Mojito B&B

3 out of 5

Price was $888, price is now $602 per person

$602

per person

Apr 5 - Apr 9

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Farallón Beach are located nearby.

Megapolis Hotel Panamá

4.5 out of 5

Price was $1,505, price is now $1,022 per person

$1,022

per person

Mar 15 - Mar 20

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Hotel Riu Plaza Panama

5 out of 5

Price was $1,128, price is now $788 per person

$788

per person

Mar 15 - Mar 20

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Casa Fofo Family House

3 out of 5

Price was $1,329, price is now $943 per person

$943

per person

Apr 5 - Apr 9

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this guesthouse in San Carlos. Enjoy free WiFi, free parking, and private pools. Popular attractions Playa La Ensenada and Playa El Palmar are located nearby.

Las Americas Golden Tower Panama

4 out of 5

Price was $710, price is now $526 per person

$526

per person

Apr 23 - Apr 26

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

La Concordia Boutique Hotel

4 out of 5

Price was $1,150, price is now $857 per person

$857

per person

Apr 6 - Apr 10

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this family-friendly hotel in Panama City. Enjoy free WiFi, a rooftop terrace, and onsite spa services. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.