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Santa Cruz Vacation Packages

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Santa Cruz
Chiriquí Province
Panama
Mexico and Central America
Hotwire.com

Santa Cruz Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Mahogany Suites

2 out of 5

Price was $744, price is now $536 per person

$536

per person

Feb 12 - Feb 15

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this golf hotel in Arraijan. Enjoy free WiFi, a golf course, and an outdoor pool. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

Central Hotel Panama Casco Viejo

4 out of 5

Save 100% on your flight

Price was $2,418, price is now $1,562 per person

$1,562

per person

Jan 6 - Jan 13

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Yoo by Wynwood House

4 out of 5

Save 100% on your flight

Price was $1,643, price is now $1,140 per person

$1,140

per person

Feb 14 - Feb 19

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this condo in Panama City. Enjoy free WiFi, a fitness center, and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Hotel Riu Plaza Panama

5 out of 5

Price was $1,002, price is now $696 per person

$696

per person

Feb 14 - Feb 19

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Ciel y Miel

3 out of 5

Price was $1,216, price is now $848 per person

$848

per person

Feb 13 - Feb 16

found 1 day ago

Roundtrip flight included

Fort Lauderdale (FLL) to Panama City (PTY)

Book a stay at this beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

MARINN Tropical Vibes Hotel

3.5 out of 5

Price was $998, price is now $699 per person

$699

per person

Jan 6 - Jan 13

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Fuerte Amador Resort & Marina are located nearby.

La Concordia Boutique Hotel

4 out of 5

Save 100% on your flight

Price was $2,349, price is now $1,684 per person

$1,684

per person

Jan 6 - Jan 13

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this family-friendly hotel in Panama City. Enjoy free WiFi, a rooftop terrace, and onsite spa services. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Summit Rainforest & Golf Resort

4 out of 5

Price was $850, price is now $620 per person

$620

per person

Feb 6 - Feb 11

found 12 hours ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this golf hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Centenario Bridge and Summit Botanical Gardens & Zoo are located nearby.