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Santa Cruz

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Santa Cruz Flights as Low as $1,309

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

United
Tue, Jan 28 - Fri, Feb 28
CLE
Hopkins Intl.
DAV
Enrique Malek Intl.
$1,309 Roundtrip, found 22 hours ago
$1,309
Roundtrip
found 22 hours ago
Select United flight, departing Tue, Jan 28 from Hopkins Intl. to Enrique Malek Intl., returning Fri, Feb 28, priced at $1,309 found 22 hours ago
United
Tue, Jan 28 - Fri, Feb 28
CLE
Hopkins Intl.
DAV
Enrique Malek Intl.
$1,320 Roundtrip, found 22 hours ago
$1,320
Roundtrip
found 22 hours ago
Select United flight, departing Tue, Jan 28 from Hopkins Intl. to Enrique Malek Intl., returning Fri, Feb 28, priced at $1,320 found 22 hours ago
United
Tue, Jan 28 - Fri, Feb 28
CLE
Hopkins Intl.
DAV
Enrique Malek Intl.
$1,344 Roundtrip, found 22 hours ago
$1,344
Roundtrip
found 22 hours ago
Select United flight, departing Tue, Jan 28 from Hopkins Intl. to Enrique Malek Intl., returning Fri, Feb 28, priced at $1,344 found 22 hours ago
United
Tue, Jan 28 - Fri, Feb 28
CLE
Hopkins Intl.
DAV
Enrique Malek Intl.
$1,357 Roundtrip, found 22 hours ago
$1,357
Roundtrip
found 22 hours ago
Select United flight, departing Tue, Jan 28 from Hopkins Intl. to Enrique Malek Intl., returning Fri, Feb 28, priced at $1,357 found 22 hours ago
Copa
Tue, Jan 28 - Fri, Feb 28
CLE
Hopkins Intl.
DAV
Enrique Malek Intl.
$1,364 Roundtrip, found 22 hours ago
$1,364
Roundtrip
found 22 hours ago
Select Copa flight, departing Tue, Jan 28 from Hopkins Intl. to Enrique Malek Intl., returning Fri, Feb 28, priced at $1,364 found 22 hours ago
Copa
Tue, Jan 28 - Fri, Feb 28
CLE
Hopkins Intl.
DAV
Enrique Malek Intl.
$1,374 Roundtrip, found 22 hours ago
$1,374
Roundtrip
found 22 hours ago
Select Copa flight, departing Tue, Jan 28 from Hopkins Intl. to Enrique Malek Intl., returning Fri, Feb 28, priced at $1,374 found 22 hours ago
Copa
Tue, Jan 28 - Fri, Feb 28
CLE
Hopkins Intl.
DAV
Enrique Malek Intl.
$1,385 Roundtrip, found 22 hours ago
$1,385
Roundtrip
found 22 hours ago
Select Copa flight, departing Tue, Jan 28 from Hopkins Intl. to Enrique Malek Intl., returning Fri, Feb 28, priced at $1,385 found 22 hours ago
United
Tue, Jan 28 - Fri, Feb 28
CLE
Hopkins Intl.
DAV
Enrique Malek Intl.
$1,422 Roundtrip, found 22 hours ago
$1,422
Roundtrip
found 22 hours ago
Select United flight, departing Tue, Jan 28 from Hopkins Intl. to Enrique Malek Intl., returning Fri, Feb 28, priced at $1,422 found 22 hours ago
United
Tue, Jan 28 - Fri, Feb 28
CLE
Hopkins Intl.
DAV
Enrique Malek Intl.
$1,431 Roundtrip, found 22 hours ago
$1,431
Roundtrip
found 22 hours ago
Select United flight, departing Tue, Jan 28 from Hopkins Intl. to Enrique Malek Intl., returning Fri, Feb 28, priced at $1,431 found 22 hours ago
Copa
Tue, Jan 28 - Fri, Feb 28
CLE
Hopkins Intl.
DAV
Enrique Malek Intl.
$1,501 Roundtrip, found 22 hours ago
$1,501
Roundtrip
found 22 hours ago
Select Copa flight, departing Tue, Jan 28 from Hopkins Intl. to Enrique Malek Intl., returning Fri, Feb 28, priced at $1,501 found 22 hours ago
United
Tue, Jan 28 - Fri, Feb 28
CLE
Hopkins Intl.
DAV
Enrique Malek Intl.
$1,502 Roundtrip, found 22 hours ago
$1,502
Roundtrip
found 22 hours ago
Select United flight, departing Tue, Jan 28 from Hopkins Intl. to Enrique Malek Intl., returning Fri, Feb 28, priced at $1,502 found 22 hours ago
United
Tue, Jan 28 - Fri, Feb 28
CLE
Hopkins Intl.
DAV
Enrique Malek Intl.
$1,507 Roundtrip, found 22 hours ago
$1,507
Roundtrip
found 22 hours ago
Select United flight, departing Tue, Jan 28 from Hopkins Intl. to Enrique Malek Intl., returning Fri, Feb 28, priced at $1,507 found 22 hours ago
Copa
Tue, Jan 28 - Fri, Feb 28
CLE
Hopkins Intl.
DAV
Enrique Malek Intl.
$1,511 Roundtrip, found 22 hours ago
$1,511
Roundtrip
found 22 hours ago
Select Copa flight, departing Tue, Jan 28 from Hopkins Intl. to Enrique Malek Intl., returning Fri, Feb 28, priced at $1,511 found 22 hours ago
United
Tue, Jan 28 - Fri, Feb 28
CLE
Hopkins Intl.
DAV
Enrique Malek Intl.
$1,512 Roundtrip, found 22 hours ago
$1,512
Roundtrip
found 22 hours ago
Select United flight, departing Tue, Jan 28 from Hopkins Intl. to Enrique Malek Intl., returning Fri, Feb 28, priced at $1,512 found 22 hours ago
United
Tue, Jan 28 - Fri, Feb 28
CLE
Hopkins Intl.
DAV
Enrique Malek Intl.
$1,526 Roundtrip, found 22 hours ago
$1,526
Roundtrip
found 22 hours ago
Select United flight, departing Tue, Jan 28 from Hopkins Intl. to Enrique Malek Intl., returning Fri, Feb 28, priced at $1,526 found 22 hours ago
United
Tue, Jan 28 - Fri, Feb 28
CLE
Hopkins Intl.
DAV
Enrique Malek Intl.
$1,536 Roundtrip, found 22 hours ago
$1,536
Roundtrip
found 22 hours ago
Select United flight, departing Tue, Jan 28 from Hopkins Intl. to Enrique Malek Intl., returning Fri, Feb 28, priced at $1,536 found 22 hours ago

Cheap Flights to Santa Cruz

Fall in love at first flight with your vacation to Santa Cruz by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Cruz on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Cruz, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Cruz

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Cruz with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DAV airport.

What is the cheapest month to fly to Santa Cruz?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Cruz are in January, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Cruz?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Cruz.

What airport is best to fly into Santa Cruz?

When you’re planning your trip to Santa Cruz, convenience is the name of the game. Luckily, Santa Cruz Enrique Malek Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santa Cruz must-do list.

How much are flights to Santa Cruz?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Cruz on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $1,309, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Cruz?

The trick to saving a stack of cash on your flight to Santa Cruz? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $1,309 right now, why wait?

Santa Cruz Flight Information
Destination airport
Enrique Malek Intl.
Destination airport IATA code
DAV
Roundtrip price
$1,309

Last Minute Hotel Deals in Santa Cruz

Hotel Bambito By Faranda Boutique, a member of Radisson Individuals
Hotel Bambito By Faranda Boutique, a member of Radisson Individuals
3 out of 5
Volcan, Via Cerro Punta, Volcan, Chiriqui
The price is $107 per night from Feb 2 to Feb 3
$107
includes taxes & fees
Feb 2 - Feb 3
Stay at this 3-star family-friendly hotel in Volcan. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Barriles and Área Silvestre Protegida ...
8/10 Very Good! (207 reviews)
"It began with the friendly hospitality of Edith at check in. Actually, everyone at the front desk was , really great! It’s not surprising, because Romero, the manager comes across as a really nice guy, and it’s been my experience that nice people enjoy working with a nice boss! And, the mood is contagious ..."

Reviewed on Jan 21, 2025

Hotel Bambito By Faranda Boutique, a member of Radisson Individuals
Casa Grande Bambito Resort
Casa Grande Bambito Resort
4 out of 5
Calle El Manantial, Paso Ancho, Chiriqui
Stay at this 4-star family-friendly hotel in Paso Ancho. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Barriles and Área Silvestre ...
8.2/10 Very Good! (98 reviews)
"Beautiful property in the woods. The hotel restaurant serves wonderful foods. Lots of nature and fresh air. The room was good and had hot water for shower. Internet WiFi was spotty at best but we did have good mobile reception. Good location."

Reviewed on Apr 17, 2024

Get rates
Casa Grande Bambito Resort
Hotel Dos Rios
Hotel Dos Rios
3 out of 5
43, Nueva California, Nueva California
The price is $98 per night from Jan 28 to Jan 29
$98
includes taxes & fees
Jan 28 - Jan 29
Stay at this 3-star hotel in Nueva California. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Barriles and Área Silvestre Protegida Lagunas ...
8.4/10 Very Good! (59 reviews)
"The hotel is being updated so it will be even better in the future, the restaurant and grounds are great!"

Reviewed on Sep 30, 2024

Hotel Dos Rios
Hotel Finca Lerida
Hotel Finca Lerida
3 out of 5
Alto Quiel, Los Naranjos, Chiriqui
The price is $236 per night from Feb 25 to Feb 26
$236
includes taxes & fees
Feb 25 - Feb 26
Stay at this 3-star hotel in Los Naranjos. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Finca Lérida Coffee Estate and Los Ladrillos ...
8.6/10 Excellent! (174 reviews)
"Arriving at night during rainfall, it was difficult to find the reception. We eventually did, but the receptionist wasn’t there at the moment. Once we found her she was very kind and helpful. Food at the restaurant is wonderful. Couldn’t figure out how to operate the TV. As part of the location, ..."

Reviewed on Nov 7, 2024

Hotel Finca Lerida
Bed and Breakfast Little Italy
Bed and Breakfast Little Italy
3 out of 5
Urb. Dona Fela 40, Varital de Boqueron, Tijeras
The price is $39 per night from Jan 27 to Jan 28
$39
includes taxes & fees
Jan 27 - Jan 28
Stay at this 3-star B&B in Tijeras. Enjoy free WiFi, free parking, and breakfast (surcharge).
9.2/10 Wonderful! (46 reviews)
"The stay was awesome. Erik and his wife were totally accommodating and cooked an awesome breakfast!"

Reviewed on Dec 13, 2024

Bed and Breakfast Little Italy
Los Quetzales Ecolodge & Spa
Los Quetzales Ecolodge & Spa
3 out of 5
Guadalupe, Cerro Punta, Chiriqui
The price is $103 per night from Jan 26 to Jan 27
$103
includes taxes & fees
Jan 26 - Jan 27
Stay at this 3-star spa lodge in Cerro Punta. Enjoy free WiFi, free parking, and a full-service spa. Popular attractions Finca Dracula Orchid Sanctuary and Volcan ...
8.4/10 Very Good! (23 reviews)
If you look for cool weather in Panama!
"We were there just one night. Got there past 8 pm, hungry and the restaurant was already closed, didn’t get much help from the staff. It took them half an hour to charge my credit card for the cost of the room and we had to drive 20 minutes, back to the city, to find a place to eat. Back at the room ..."

Reviewed on Jan 13, 2025

Los Quetzales Ecolodge & Spa
Linda Vista Cabins
Linda Vista Cabins
3 out of 5
Calle 35 sur oeste, Urb. Linda Vista, Alto Boquete, Chiriqui
The price is $64 per night from Feb 22 to Feb 23
$64
includes taxes & fees
Feb 22 - Feb 23
Stay at this 3-star cabin in Alto Boquete. Enjoy free WiFi, free parking, and a garden. Popular attractions Schumann's Park and Boquete Library are located ...
9/10 Wonderful! (15 reviews)
RELAX
"It was a pleasant and quiet stay. A good place to take a relax. Also my puppies had a place to run and play."

Reviewed on Jun 14, 2023

Linda Vista Cabins
Hostal Victoria Volcán Chiriquí S. A.
Hostal Victoria Volcán Chiriquí S. A.
2 out of 5
Volcan Chiriquí, Calle Estudiante Calle 3era y Calle 4ta, Nueva California, Chiriquí
The price is $55 per night from Jan 26 to Jan 27
$55
includes taxes & fees
Jan 26 - Jan 27
Stay at this hostal in Nueva California. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Barriles and Área Silvestre Protegida Lagunas ...
8.6/10 Excellent! (6 reviews)
"I found it to be a comfortable and friendly place. Snacks and coffee available, and walkable to dining options. I liked the large display with local activities mapped."

Reviewed on May 19, 2024

Hostal Victoria Volcán Chiriquí S. A.
See all 44 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.