Search Cheap Flights to
Santa Cruz

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Santa Cruz Flights as Low as $272

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Copa
Copa
Copa
Copa
Copa
Copa
Copa
Copa
Copa
Copa
Copa
Copa
APG Distribution System
Copa
United

Cheap Flights to Santa Cruz

Fall in love at first flight with your vacation to Santa Cruz by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Cruz on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Cruz, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Cruz

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Cruz with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DAV airport.

What is the cheapest month to fly to Santa Cruz?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Cruz are in April, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Cruz?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Cruz.

What airport is best to fly into Santa Cruz?

When you’re planning your trip to Santa Cruz, convenience is the name of the game. Luckily, Santa Cruz Enrique Malek Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santa Cruz must-do list.

How much are flights to Santa Cruz?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Cruz on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $272, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Cruz?

The trick to saving a stack of cash on your flight to Santa Cruz? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $272 right now, why wait?

Santa Cruz Flight Information
Destination airport
Enrique Malek Intl.
Destination airport IATA code
DAV
Roundtrip price
$272

Last Minute Hotel Deals in Santa Cruz

Hotel Bambito By Faranda Boutique, a member of Radisson Individuals

Hotel Bambito By Faranda Boutique, a member of Radisson Individuals

3 out of 5
Volcan, Via Cerro Punta Volcan Chiriqui
Book a stay at this family-friendly hotel in Volcan. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Barriles and Área Silvestre Protegida ...
8/10 Very Good! (242 reviews)
Very clean room

Reviewed on Jan 9, 2026

Hotel Bambito By Faranda Boutique, a member of Radisson Individuals
Hotel Finca Lerida

Hotel Finca Lerida

3 out of 5
Alto Quiel Los Naranjos Chiriqui
Stay at this hotel in Los Naranjos. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Finca Lérida Coffee Estate and Los Ladrillos are located ...
8.8/10 Excellent! (188 reviews)
Spotless room and bathroom, the amazing staff that treats you like family, coffee tour and tasting is a must, very good food.

Reviewed on Jan 13, 2026

Hotel Finca Lerida
Hotel Dos Rios

Hotel Dos Rios

3 out of 5
43, Nueva California Nueva California
Stay at this hotel in Nueva California. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Barriles and Área Silvestre Protegida Lagunas ...
8.6/10 Excellent! (75 reviews)
I loved my room. Would have stayed longer if it was available

Reviewed on Jan 13, 2026

Hotel Dos Rios
Los Quetzales Ecolodge & Spa

Los Quetzales Ecolodge & Spa

3 out of 5
Guadalupe Cerro Punta Chiriqui
Book a stay at this spa lodge in Cerro Punta. Enjoy free WiFi, free parking, and a full-service spa. Popular attractions Finca Dracula Orchid Sanctuary and The ...
8.6/10 Excellent! (33 reviews)
Patricia was a great host

Reviewed on Dec 22, 2025

Los Quetzales Ecolodge & Spa
Little Italy B&B

Little Italy B&B

3 out of 5
Urb. Dona Fela 40 Tijeras
Book a stay at this business-friendly B&B in Tijeras. Enjoy free breakfast, free WiFi, and free parking.
9.2/10 Wonderful! (51 reviews)
Like the title
Convenient to reach from Concepcion

Reviewed on Aug 10, 2025

Little Italy B&B
Los Brezos Boutique Hotel

Los Brezos Boutique Hotel

3.5 out of 5
Calle Tercera Norte Volcan Chiriquí
Book a stay at this business-friendly hotel in Volcan. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Barriles and Área Silvestre Protegida ...
9.2/10 Wonderful! (28 reviews)
It was nice. I wasn’t there long as I left very early to go on a birding trip

Reviewed on Jan 4, 2026

Los Brezos Boutique Hotel
Casa Grande Bambito Resort

Casa Grande Bambito Resort

4 out of 5
Calle El Manantial Paso Ancho Chiriqui
Book a stay at this family-friendly hotel in Paso Ancho. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Barriles and Área Silvestre ...
8.2/10 Very Good! (99 reviews)
We went for 3 days to the Junior Suite 1. First day there was a wedding. Noise all night long When we got there, the TV did not work. Wifi slow and sometimes it went down. Antes on the sink, the staff told me that "usually happens". No mosquito screen. You need to sleep with windows opens, which ...

Reviewed on Jan 15, 2025

Casa Grande Bambito Resort
Luxury Canyon Suites

Luxury Canyon Suites

2 out of 5
La Tranca Alto Boquete Provincia de Chiriquí
Stay at this hotel in Alto Boquete. Enjoy free WiFi, daily housekeeping, and meeting facilities. Popular attractions Boquete Community Market and Schumann's ...
7.6/10 Good! (4 reviews)
New place, still developing

Reviewed on Mar 4, 2025

Luxury Canyon Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.