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Santa Cruz Vacation Packages

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Santa Cruz
Chiriquí Province
Panama
Mexico and Central America
Hotwire.com

Santa Cruz Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Summit Rainforest & Golf Resort

4 out of 5

Price was $850, price is now $620 per person

$620

per person

Feb 6 - Feb 11

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this golf hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Centenario Bridge and Summit Botanical Gardens & Zoo are located nearby.

Mahogany Suites

2 out of 5

Price was $1,239, price is now $641 per person

$641

per person

Jan 8 - Jan 13

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this golf hotel in Arraijan. Enjoy free WiFi, a golf course, and an outdoor pool. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

Central Hotel Panama Casco Viejo

4 out of 5

Save 100% on your flight

Price was $1,547, price is now $987 per person

$987

per person

Feb 17 - Feb 21

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Casa Mallet by Wynwood House

4 out of 5

Save 100% on your flight

Price was $2,000, price is now $1,452 per person

$1,452

per person

Feb 14 - Feb 19

found 21 hours ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Riande Aeropuerto Hotel & Casino

4 out of 5

Price was $1,118, price is now $812 per person

$812

per person

Feb 25 - Mar 2

found 12 hours ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.

Hotel Riu Plaza Panama

5 out of 5

Price was $883, price is now $642 per person

$642

per person

Feb 17 - Feb 21

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Dreams Playa Bonita Panama - All Inclusive

4 out of 5

Save 100% on your flight

Price was $2,121, price is now $1,562 per person

$1,562

per person

Jan 8 - Jan 13

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

Yoo by Wynwood House

4 out of 5

Price was $1,665, price is now $1,238 per person

$1,238

per person

Feb 14 - Feb 19

found 21 hours ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this condo in Panama City. Enjoy free WiFi, a fitness center, and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.