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Serena

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Serena Flights as Low as $162

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Spirit Airlines
Tue, Apr 8 - Mon, Apr 14
PNS
Pensacola Intl.
ORD
O'Hare Intl.
$162 Roundtrip, found 1 day ago
$162
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Tue, Apr 8 from Pensacola Intl. to O'Hare Intl., returning Mon, Apr 14, priced at $162 found 1 day ago
Spirit Airlines
Tue, Apr 1 - Sun, Apr 6
PNS
Pensacola Intl.
ORD
O'Hare Intl.
$169 Roundtrip, found 4 days ago
$169
Roundtrip
found 4 days ago
Select Spirit Airlines flight, departing Tue, Apr 1 from Pensacola Intl. to O'Hare Intl., returning Sun, Apr 6, priced at $169 found 4 days ago
Spirit Airlines
Tue, Apr 8 - Sun, Apr 13
PNS
Pensacola Intl.
ORD
O'Hare Intl.
$177 Roundtrip, found 1 day ago
$177
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Tue, Apr 8 from Pensacola Intl. to O'Hare Intl., returning Sun, Apr 13, priced at $177 found 1 day ago
Spirit Airlines
Sun, Apr 6 - Mon, Apr 14
PNS
Pensacola Intl.
ORD
O'Hare Intl.
$193 Roundtrip, found 1 day ago
$193
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Sun, Apr 6 from Pensacola Intl. to O'Hare Intl., returning Mon, Apr 14, priced at $193 found 1 day ago
Spirit Airlines
Wed, Apr 9 - Mon, Apr 14
PNS
Pensacola Intl.
ORD
O'Hare Intl.
$200 Roundtrip, found 1 day ago
$200
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Wed, Apr 9 from Pensacola Intl. to O'Hare Intl., returning Mon, Apr 14, priced at $200 found 1 day ago
Spirit Airlines
Thu, Apr 10 - Mon, Apr 14
PNS
Pensacola Intl.
ORD
O'Hare Intl.
$200 Roundtrip, found 1 day ago
$200
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Thu, Apr 10 from Pensacola Intl. to O'Hare Intl., returning Mon, Apr 14, priced at $200 found 1 day ago
Spirit Airlines
Sun, Apr 6 - Sun, Apr 13
PNS
Pensacola Intl.
ORD
O'Hare Intl.
$208 Roundtrip, found 1 day ago
$208
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Sun, Apr 6 from Pensacola Intl. to O'Hare Intl., returning Sun, Apr 13, priced at $208 found 1 day ago
Spirit Airlines
Tue, Apr 8 - Tue, Apr 8
PNS
Pensacola Intl.
ORD
O'Hare Intl.
$213 Roundtrip, found 1 day ago
$213
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Tue, Apr 8 from Pensacola Intl. to O'Hare Intl., returning Tue, Apr 8, priced at $213 found 1 day ago
Spirit Airlines
Wed, Apr 9 - Sun, Apr 13
PNS
Pensacola Intl.
ORD
O'Hare Intl.
$215 Roundtrip, found 1 day ago
$215
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Wed, Apr 9 from Pensacola Intl. to O'Hare Intl., returning Sun, Apr 13, priced at $215 found 1 day ago
Spirit Airlines
Thu, Apr 10 - Sun, Apr 13
PNS
Pensacola Intl.
ORD
O'Hare Intl.
$215 Roundtrip, found 1 day ago
$215
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Thu, Apr 10 from Pensacola Intl. to O'Hare Intl., returning Sun, Apr 13, priced at $215 found 1 day ago
Spirit Airlines
Mon, Apr 7 - Mon, Apr 14
PNS
Pensacola Intl.
ORD
O'Hare Intl.
$216 Roundtrip, found 1 day ago
$216
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Mon, Apr 7 from Pensacola Intl. to O'Hare Intl., returning Mon, Apr 14, priced at $216 found 1 day ago
Delta
Wed, Jun 4 - Wed, Jun 11
PNS
Pensacola Intl.
ORD
O'Hare Intl.
$218 Roundtrip, found 6 days ago
$218
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Jun 4 from Pensacola Intl. to O'Hare Intl., returning Wed, Jun 11, priced at $218 found 6 days ago
Delta
Tue, Jun 3 - Wed, Jun 11
PNS
Pensacola Intl.
ORD
O'Hare Intl.
$218 Roundtrip, found 6 days ago
$218
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Jun 3 from Pensacola Intl. to O'Hare Intl., returning Wed, Jun 11, priced at $218 found 6 days ago
American Airlines
Thu, Jun 5 - Sun, Jun 8
PNS
Pensacola Intl.
ORD
O'Hare Intl.
$284 Roundtrip, found 6 days ago
$284
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Jun 5 from Pensacola Intl. to O'Hare Intl., returning Sun, Jun 8, priced at $284 found 6 days ago
Frontier Airlines
Fri, Mar 28 - Wed, Apr 9
PNS
Pensacola Intl.
ORD
O'Hare Intl.
$292 Roundtrip, found 4 days ago
$292
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Fri, Mar 28 from Pensacola Intl. to O'Hare Intl., returning Wed, Apr 9, priced at $292 found 4 days ago
United
Sat, May 10 - Sat, Aug 23
PNS
Pensacola Intl.
PIA
Greater Peoria Regional
$298 Roundtrip, found 14 hours ago
$298
Roundtrip
found 14 hours ago
Select United flight, departing Sat, May 10 from Pensacola Intl. to Greater Peoria Regional, returning Sat, Aug 23, priced at $298 found 14 hours ago

Cheap Flights to Serena

Fall in love at first flight with your vacation to Serena by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Serena on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Serena, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Serena

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Serena with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the VYS airport.

What is the cheapest month to fly to Serena?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Serena are in April, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Serena?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Serena.

What airport is best to fly into Serena?

When you’re planning your trip to Serena, convenience is the name of the game. Luckily, Serena Dupage Airport is nearby so you can deplane and get going on checking off everything on your Serena must-do list.

How much are flights to Serena?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Serena on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $162, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Serena?

The trick to saving a stack of cash on your flight to Serena? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $162 right now, why wait?

Serena Flight Information
Destination airport
O'Hare Intl.
Destination airport IATA code
ORD
Roundtrip price
$96

Last Minute Hotel Deals in Serena

Grand Bear Resort at Starved Rock
Grand Bear Resort at Starved Rock
3 out of 5
2643 IL-178, Utica, IL
The price is $187 per night from Apr 13 to Apr 14
$187
includes taxes & fees
Apr 13 - Apr 14
Stay at this 3-star golf hotel in Utica. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.2/10 Good! (756 reviews)
"Everything was great"

Reviewed on Mar 25, 2025

Grand Bear Resort at Starved Rock
Hampton Inn Yorkville
Hampton Inn Yorkville
2.5 out of 5
310 East Countryside Parkway, Yorkville, IL
The price is $109 per night from Apr 6 to Apr 7
$109
includes taxes & fees
Apr 6 - Apr 7
Book a stay at this business-friendly hotel in Yorkville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (797 reviews)
Really Good
"It was very clean, had a clean smell. Some of the amenities were good. Nice sized tv. The breakfast in the mornigs was very good and filling. Customer service was great and with a smile."

Reviewed on Mar 18, 2025

Hampton Inn Yorkville
Holiday Inn Club Vacations Fox River Resort at Sheridan by IHG
Holiday Inn Club Vacations Fox River Resort at Sheridan by IHG
3.5 out of 5
2558 N 3653 Road, Sheridan, IL
The price is $111 per night from Mar 31 to Apr 1
$111
includes taxes & fees
Mar 31 - Apr 1
Stay at this 3.5-star golf aparthotel in Sheridan. Enjoy free parking, an outdoor pool, and a golf course. Our guests praise the helpful staff in our ...
8.2/10 Very Good! (494 reviews)
Nice stay
"Check in was nice and the room was a good size. The beds were pretty comfortable. The fridge leaked, the bedroom was freezing no matter what the heat was set at and the water pressure is pretty low. The waterpark not being included and being additional money per person is pretty crazy too considering ..."

Reviewed on Mar 23, 2025

Holiday Inn Club Vacations Fox River Resort at Sheridan by IHG
Days Inn by Wyndham Oglesby/ Starved Rock
Days Inn by Wyndham Oglesby/ Starved Rock
2 out of 5
120 N Lewis Ave, Oglesby, IL
The price is $74 per night from Apr 2 to Apr 3
$74
includes taxes & fees
Apr 2 - Apr 3
Book a stay at this business-friendly hotel in Oglesby. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,000 reviews)
"The east end of the building is coming apart. The siding"

Reviewed on Mar 25, 2025

Days Inn by Wyndham Oglesby/ Starved Rock
Comfort Inn Morris I-80
Comfort Inn Morris I-80
2.5 out of 5
70 Gore Rd, Morris, IL
The price is $99 per night from Apr 6 to Apr 7
$99
includes taxes & fees
Apr 6 - Apr 7
Book a stay at this business-friendly hotel in Morris. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (541 reviews)
Nice stay for the night.
"Very friendly check in staff, room was very clean, and comfortable. Will return again"

Reviewed on Feb 14, 2025

Comfort Inn Morris I-80
Holiday Inn Express & Suites Yorkville by IHG
Holiday Inn Express & Suites Yorkville by IHG
2.5 out of 5
577 E KENDALL DRIVE, Yorkville, IL
The price is $93 per night from Apr 6 to Apr 7
$93
includes taxes & fees
Apr 6 - Apr 7
Book a stay at this spa hotel in Yorkville. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.2/10 Very Good! (511 reviews)
"Easy to find, clean and more modern property and amenities. The pool and spa were open on the night we checked in, so that was a nice perk. Good choices for breakfast too."

Reviewed on Mar 2, 2025

Holiday Inn Express & Suites Yorkville by IHG
Days Inn & Suites by Wyndham of Morris
Days Inn & Suites by Wyndham of Morris
2 out of 5
80 Hampton Road, Morris, IL
The price is $80 per night from Mar 28 to Mar 29
$80
includes taxes & fees
Mar 28 - Mar 29
Book a stay at this business-friendly hotel in Morris. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff and ...
6.8/10 (762 reviews)
"I enjoyed my stay and I do like to upgraded facility."

Reviewed on Jan 20, 2025

Days Inn & Suites by Wyndham of Morris
Best Western Oglesby Inn
Best Western Oglesby Inn
2.5 out of 5
900 Holiday Street, Oglesby, IL
The price is $99 per night from Mar 27 to Mar 28
$99
includes taxes & fees
Mar 27 - Mar 28
Book a stay at this business-friendly hotel in Oglesby. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
8/10 Very Good! (1,000 reviews)
Weekend getaway
"Great price, great location, friendly staff."

Reviewed on Mar 24, 2025

Best Western Oglesby Inn
See all 358 properties in Serena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.