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Serena

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Serena Flights as Low as $90

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Spirit Airlines
Sat, Sep 27 - Tue, Sep 30
LGA
LaGuardia
ORD
O'Hare Intl.
$90 Roundtrip, found 5 hours ago
$90
Roundtrip
found 5 hours ago
Select Spirit Airlines flight, departing Sat, Sep 27 from LaGuardia to O'Hare Intl., returning Tue, Sep 30, priced at $90 found 5 hours ago
United
Wed, Aug 13 - Tue, Aug 19
LGA
LaGuardia
ORD
O'Hare Intl.
$93 Roundtrip, found 1 day ago
$93
Roundtrip
found 1 day ago
Select United flight, departing Wed, Aug 13 from LaGuardia to O'Hare Intl., returning Tue, Aug 19, priced at $93 found 1 day ago
United
Mon, Aug 4 - Mon, Aug 11
LGA
LaGuardia
ORD
O'Hare Intl.
$97 Roundtrip, found 1 day ago
$97
Roundtrip
found 1 day ago
Select United flight, departing Mon, Aug 4 from LaGuardia to O'Hare Intl., returning Mon, Aug 11, priced at $97 found 1 day ago
United
Fri, Sep 19 - Wed, Sep 24
LGA
LaGuardia
ORD
O'Hare Intl.
$98 Roundtrip, found 2 days ago
$98
Roundtrip
found 2 days ago
Select United flight, departing Fri, Sep 19 from LaGuardia to O'Hare Intl., returning Wed, Sep 24, priced at $98 found 2 days ago
Spirit Airlines
Tue, Aug 26 - Sat, Aug 30
LAX
Los Angeles Intl.
ORD
O'Hare Intl.
$130 Roundtrip, found 3 hours ago
$130
Roundtrip
found 3 hours ago
Select Spirit Airlines flight, departing Tue, Aug 26 from Los Angeles Intl. to O'Hare Intl., returning Sat, Aug 30, priced at $130 found 3 hours ago
Delta
Tue, Aug 5 - Tue, Aug 12
LGA
LaGuardia
ORD
O'Hare Intl.
$139 Roundtrip, found 1 day ago
$139
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Aug 5 from LaGuardia to O'Hare Intl., returning Tue, Aug 12, priced at $139 found 1 day ago
American Airlines
Sat, Sep 27 - Tue, Sep 30
LGA
LaGuardia
ORD
O'Hare Intl.
$147 Roundtrip, found 5 hours ago
$147
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sat, Sep 27 from LaGuardia to O'Hare Intl., returning Tue, Sep 30, priced at $147 found 5 hours ago
American Airlines
Tue, Sep 9 - Sat, Sep 13
PHX
Sky Harbor Intl.
ORD
O'Hare Intl.
$149 Roundtrip, found 1 day ago
$149
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Sep 9 from Sky Harbor Intl. to O'Hare Intl., returning Sat, Sep 13, priced at $149 found 1 day ago
Frontier Airlines
Sat, Aug 23 - Thu, Aug 28
LAX
Los Angeles Intl.
ORD
O'Hare Intl.
$177 Roundtrip, found 3 days ago
$177
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sat, Aug 23 from Los Angeles Intl. to O'Hare Intl., returning Thu, Aug 28, priced at $177 found 3 days ago
Frontier Airlines
Thu, Aug 28 - Thu, Sep 4
PHX
Sky Harbor Intl.
MDW
Midway Intl.
$197 Roundtrip, found 2 days ago
$197
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Aug 28 from Sky Harbor Intl. to Midway Intl., returning Thu, Sep 4, priced at $197 found 2 days ago
Hawaiian Airlines
Tue, Oct 7 - Wed, Oct 15
PHX
Sky Harbor Intl.
ORD
O'Hare Intl.
$203 Roundtrip, found 3 days ago
$203
Roundtrip
found 3 days ago
Select Hawaiian Airlines flight, departing Tue, Oct 7 from Sky Harbor Intl. to O'Hare Intl., returning Wed, Oct 15, priced at $203 found 3 days ago
Alaska Airlines
Tue, Oct 14 - Mon, Oct 27
PHX
Sky Harbor Intl.
ORD
O'Hare Intl.
$204 Roundtrip, found 2 days ago
$204
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Tue, Oct 14 from Sky Harbor Intl. to O'Hare Intl., returning Mon, Oct 27, priced at $204 found 2 days ago
Delta
Tue, Nov 4 - Tue, Nov 11
LGA
LaGuardia
MDW
Midway Intl.
$217 Roundtrip, found 1 day ago
$217
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Nov 4 from LaGuardia to Midway Intl., returning Tue, Nov 11, priced at $217 found 1 day ago
Delta
Tue, Sep 2 - Wed, Sep 3
LAX
Los Angeles Intl.
MDW
Midway Intl.
$251 Roundtrip, found 9 hours ago
$251
Roundtrip
found 9 hours ago
Select Delta flight, departing Tue, Sep 2 from Los Angeles Intl. to Midway Intl., returning Wed, Sep 3, priced at $251 found 9 hours ago
JetBlue Airways
Tue, Oct 14 - Tue, Oct 28
LAX
Los Angeles Intl.
ORD
O'Hare Intl.
$327 Roundtrip, found 23 hours ago
$327
Roundtrip
found 23 hours ago
Select JetBlue Airways flight, departing Tue, Oct 14 from Los Angeles Intl. to O'Hare Intl., returning Tue, Oct 28, priced at $327 found 23 hours ago
Sun Country Airlines
Wed, Oct 15 - Sun, Oct 19
LAX
Los Angeles Intl.
ORD
O'Hare Intl.
$343 Roundtrip, found 1 day ago
$343
Roundtrip
found 1 day ago
Select Sun Country Airlines flight, departing Wed, Oct 15 from Los Angeles Intl. to O'Hare Intl., returning Sun, Oct 19, priced at $343 found 1 day ago

Cheap Flights to Serena

Fall in love at first flight with your vacation to Serena by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Serena on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Serena, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Serena

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Serena with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the VYS airport.

What is the cheapest month to fly to Serena?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Serena are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Serena?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Serena.

What airport is best to fly into Serena?

When you’re planning your trip to Serena, convenience is the name of the game. Luckily, Serena Dupage Airport is nearby so you can deplane and get going on checking off everything on your Serena must-do list.

How much are flights to Serena?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Serena on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $90, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Serena?

The trick to saving a stack of cash on your flight to Serena? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $90 right now, why wait?

Serena Flight Information
Destination airport
O'Hare Intl.
Destination airport IATA code
ORD
Roundtrip price
$155

Last Minute Hotel Deals in Serena

Grand Bear Resort at Starved Rock
Grand Bear Resort at Starved Rock
3 out of 5
2643 IL-178, Utica, IL
Stay at this 3-star golf hotel in Utica. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.2/10 Good! (855 reviews)
"Everything was great except the carpet in the room, it felt sticky,your feet were dirty just from the carpet. I had to keep shoes"

Reviewed on Jul 8, 2025

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Grand Bear Resort at Starved Rock
Holiday Inn Express & Suites Yorkville by IHG
Holiday Inn Express & Suites Yorkville by IHG
2.5 out of 5
577 E KENDALL DRIVE, Yorkville, IL
Book a stay at this spa hotel in Yorkville. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.2/10 Very Good! (553 reviews)
"Me and my kids had a great experience at this hotel , will definitely recommend"

Reviewed on Jul 8, 2025

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Holiday Inn Express & Suites Yorkville by IHG
Best Western Oglesby Inn
Best Western Oglesby Inn
2.5 out of 5
900 Holiday Street, Oglesby, IL
Book a stay at this business-friendly hotel in Oglesby. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
8/10 Very Good! (1,000 reviews)
Clean welcoming with delicious breakfast
"My family had a wonderful stay at this lovely hotel. The staff are extremely friendly and inviting. The breakfast was delicious with many options daily from fresh eggs to home style waffles. The pool was clean and a place where many guest relaxed after spending time in the nearby parks. Our room ..."

Reviewed on Jul 8, 2025

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Best Western Oglesby Inn
Comfort Inn Ottawa Starved Rock Area
Comfort Inn Ottawa Starved Rock Area
2.5 out of 5
120 W. Stevenson Road, Ottawa, IL
Book a stay at this business-friendly hotel in Ottawa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (667 reviews)
Good place to stay
"Stay was great. Good area with lots of restaurants. Breakfast was great."

Reviewed on Jun 30, 2025

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Comfort Inn Ottawa Starved Rock Area
Postcard Cabins Starved Rock
Postcard Cabins Starved Rock
2 out of 5
1879 N 2703rd Rd, Ottawa, IL
Stay at this cabin in Ottawa. Enjoy free parking, patios, and climate control. Popular attractions Tangled Roots Brewing Company - The Lone Buffalo and Washington ...
10/10 Exceptional! (33 reviews)
"By far one of the best Glamping experiences I’ve had. My children had so much fun and our Family dog enjoyed it even more. Very comfortable and cozy at the same time and best part the A/C was amazing after enjoying the hot weather. Will definitely be coming back."

Reviewed on Jul 7, 2025

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Postcard Cabins Starved Rock
Holiday Inn Club Vacations Fox River Resort at Sheridan by IHG
Holiday Inn Club Vacations Fox River Resort at Sheridan by IHG
3.5 out of 5
2558 N 3653 Road, Sheridan, IL
Stay at this 3.5-star golf aparthotel in Sheridan. Enjoy free parking, an outdoor pool, and a golf course. Our guests praise the helpful staff in our ...
8.2/10 Very Good! (544 reviews)
"Nice Facility. Great, helpful staff. Surprised by the Villa Lodge rooms. Very spacious for 5 adults and a toddler. Enjoyed the rural setting. Wildlife in the area. Disappointed by the 'green' lake so no peddle boats or fishing. But that's Mother Nature! :( Many activities to take part in throughout ..."

Reviewed on Jul 2, 2025

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Holiday Inn Club Vacations Fox River Resort at Sheridan by IHG
Days Inn & Suites by Wyndham of Morris
Days Inn & Suites by Wyndham of Morris
2 out of 5
80 Hampton Road, Morris, IL
Book a stay at this business-friendly hotel in Morris. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff and ...
6.8/10 (807 reviews)
"The owners and staff are wonderful."

Reviewed on Jul 3, 2025

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Days Inn & Suites by Wyndham of Morris
Holiday Inn Express & Suites Ottawa by IHG
Holiday Inn Express & Suites Ottawa by IHG
2.5 out of 5
2850 Columbus Street, Ottawa, IL
Book a stay at this business-friendly hotel in Ottawa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (487 reviews)
"Nice hotel- new. Breakfast was good lots of options"

Reviewed on Jul 4, 2025

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Holiday Inn Express & Suites Ottawa by IHG
See all 342 properties in Serena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.