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Serena

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Serena Flights as Low as $58

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Tue, May 12 - Wed, May 13
DEN
Denver Intl.
ORD
O'Hare Intl.
$58 Roundtrip, found 1 day ago
$58
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Tue, May 12 from Denver Intl. to O'Hare Intl., returning Wed, May 13, priced at $58 found 1 day ago
Frontier Airlines
Tue, May 12 - Tue, May 19
ATL
Hartsfield-Jackson Atlanta Intl.
MDW
Midway Intl.
$70 Roundtrip, found 11 hours ago
$70
Roundtrip
found 11 hours ago
Select Frontier Airlines flight, departing Tue, May 12 from Hartsfield-Jackson Atlanta Intl. to Midway Intl., returning Tue, May 19, priced at $70 found 11 hours ago
Frontier Airlines
Tue, Aug 18 - Tue, Sep 1
ATL
Hartsfield-Jackson Atlanta Intl.
ORD
O'Hare Intl.
$76 Roundtrip, found 1 day ago
$76
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Tue, Aug 18 from Hartsfield-Jackson Atlanta Intl. to O'Hare Intl., returning Tue, Sep 1, priced at $76 found 1 day ago
Bargain Flight
Fri, Sep 18 - Mon, Sep 21
MSP
Minneapolis - St. Paul Intl.
ORD
O'Hare Intl.
$156 Roundtrip, found 3 days ago
$156
Roundtrip
found 3 days ago
Select Bargain Flight flight, departing Fri, Sep 18 from Minneapolis - St. Paul Intl. to O'Hare Intl., returning Mon, Sep 21, priced at $156 found 3 days ago
Sun Country Airlines
Fri, Sep 18 - Mon, Sep 21
MSP
Minneapolis - St. Paul Intl.
ORD
O'Hare Intl.
$157 Roundtrip, found 3 days ago
$157
Roundtrip
found 3 days ago
Select Sun Country Airlines flight, departing Fri, Sep 18 from Minneapolis - St. Paul Intl. to O'Hare Intl., returning Mon, Sep 21, priced at $157 found 3 days ago
American Airlines
Tue, May 12 - Tue, May 19
DEN
Denver Intl.
ORD
O'Hare Intl.
$163 Roundtrip, found 1 day ago
$163
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, May 12 from Denver Intl. to O'Hare Intl., returning Tue, May 19, priced at $163 found 1 day ago
Frontier Airlines
Sat, May 16 - Sat, May 30
MSP
Minneapolis - St. Paul Intl.
MDW
Midway Intl.
$174 Roundtrip, found 19 hours ago
$174
Roundtrip
found 19 hours ago
Select Frontier Airlines flight, departing Sat, May 16 from Minneapolis - St. Paul Intl. to Midway Intl., returning Sat, May 30, priced at $174 found 19 hours ago
Frontier Airlines
Wed, May 6 - Tue, May 12
DEN
Denver Intl.
MDW
Midway Intl.
$186 Roundtrip, found 3 days ago
$186
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Wed, May 6 from Denver Intl. to Midway Intl., returning Tue, May 12, priced at $186 found 3 days ago
Bargain Flight
Fri, Jun 5 - Sun, Jun 7
MSP
Minneapolis - St. Paul Intl.
PIA
Greater Peoria Regional
$229 Roundtrip, found 1 day ago
$229
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Fri, Jun 5 from Minneapolis - St. Paul Intl. to Greater Peoria Regional, returning Sun, Jun 7, priced at $229 found 1 day ago
United
Sun, May 10 - Sun, May 24
DEN
Denver Intl.
PIA
Greater Peoria Regional
$296 Roundtrip, found 1 day ago
$296
Roundtrip
found 1 day ago
Select United flight, departing Sun, May 10 from Denver Intl. to Greater Peoria Regional, returning Sun, May 24, priced at $296 found 1 day ago
American Airlines
Thu, May 14 - Mon, May 18
ATL
Hartsfield-Jackson Atlanta Intl.
RFD
Greater Rockford
$304 Roundtrip, found 5 hours ago
$304
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Thu, May 14 from Hartsfield-Jackson Atlanta Intl. to Greater Rockford, returning Mon, May 18, priced at $304 found 5 hours ago
Delta
Fri, May 22 - Mon, Jun 8
DEN
Denver Intl.
BMI
Central Illinois Regional
$309 Roundtrip, found 2 days ago
$309
Roundtrip
found 2 days ago
Select Delta flight, departing Fri, May 22 from Denver Intl. to Central Illinois Regional, returning Mon, Jun 8, priced at $309 found 2 days ago
American Airlines
Thu, May 14 - Mon, May 18
ATL
Hartsfield-Jackson Atlanta Intl.
PIA
Greater Peoria Regional
$336 Roundtrip, found 1 day ago
$336
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, May 14 from Hartsfield-Jackson Atlanta Intl. to Greater Peoria Regional, returning Mon, May 18, priced at $336 found 1 day ago
American Airlines
Fri, May 1 - Tue, May 5
DEN
Denver Intl.
RFD
Greater Rockford
$360 Roundtrip, found 19 hours ago
$360
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Fri, May 1 from Denver Intl. to Greater Rockford, returning Tue, May 5, priced at $360 found 19 hours ago
Delta
Wed, May 27 - Sat, Jun 13
ATL
Hartsfield-Jackson Atlanta Intl.
BMI
Central Illinois Regional
$408 Roundtrip, found 1 day ago
$408
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, May 27 from Hartsfield-Jackson Atlanta Intl. to Central Illinois Regional, returning Sat, Jun 13, priced at $408 found 1 day ago
American Airlines
Thu, Apr 30 - Sun, May 3
MSP
Minneapolis - St. Paul Intl.
RFD
Greater Rockford
$510 Roundtrip, found 2 days ago
$510
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Apr 30 from Minneapolis - St. Paul Intl. to Greater Rockford, returning Sun, May 3, priced at $510 found 2 days ago

Cheap Flights to Serena

Fall in love at first flight with your vacation to Serena by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Serena on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Serena, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Serena

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Serena with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the VYS airport.

What is the cheapest month to fly to Serena?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Serena are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Serena?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to Serena.

What airport is best to fly into Serena?

When you’re planning your trip to Serena, convenience is the name of the game. Luckily, Serena Dupage Airport is nearby so you can deplane and get going on checking off everything on your Serena must-do list.

How much are flights to Serena?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Serena on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $58, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Serena?

The trick to saving a stack of cash on your flight to Serena? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $58 right now, why wait?

Serena Flight Information
Destination airport
O'Hare Intl.
Destination airport IATA code
ORD
Roundtrip price
$57

Last Minute Hotel Deals in Serena

Grand Bear Resort at Starved Rock

Grand Bear Resort at Starved Rock

3 out of 5
2643 IL-178 Utica IL
Book a stay at this golf hotel in Utica. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.2/10 Good! (1,005 reviews)
Overall we had a very nice experience. However, the lighting in our room was too dark. Definitely needed better lamps with brighter bulbs. Missing shampoo and soap for the shower. The waterpark was nice but seemed very dark. The bottom of all the pools was brown instead of a nice blue that you would ...

Reviewed on Apr 24, 2026

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Grand Bear Resort at Starved Rock
Postcard Cabins Starved Rock, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Starved Rock, Outdoor Collection by Marriott Bonvoy

2 out of 5
1879 N 2703rd Rd Ottawa IL
Stay at this cabin in Ottawa. Enjoy free parking, patios, and climate control. Popular attractions Tangled Roots Brewing Company - The Lone Buffalo and Washington ...
9.8/10 Exceptional! (180 reviews)
It’s a good get away if you want to get away from the city and connect more with nature, a lot of different bird species to admire. The staff is really well organized help us with any questions. The cabin was really well organized and clean.

Reviewed on Apr 22, 2026

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Postcard Cabins Starved Rock, Outdoor Collection by Marriott Bonvoy
Days Inn by Wyndham Oglesby/ Starved Rock

Days Inn by Wyndham Oglesby/ Starved Rock

2 out of 5
120 N Lewis Ave Oglesby IL
Book a stay at this business-friendly hotel in Oglesby. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,000 reviews)
The room and beds were clean and comfortable. The property needs some updating. In-room microwave and refrigerator were old and not in good shape. There was mold on the fridge door gasket and it didn't close well. The microwave door is a different color than the rest of the unit (clearly not a design ...

Reviewed on Apr 21, 2026

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Days Inn by Wyndham Oglesby/ Starved Rock
Days Inn & Suites by Wyndham Morris/I-80

Days Inn & Suites by Wyndham Morris/I-80

2 out of 5
80 Hampton Road Morris IL
Book a stay at this business-friendly hotel in Morris. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff and ...
7/10 Good! (910 reviews)
Continental breakfast average. Front desk clerk Michelle was always friendly and helpful. There are 2 new 100 gallon water, still their shipping containers, sitting in the hallway. I was there for 3 weeks and there was no movement to install the heaters. Hotel location was great for me. Close to ...

Reviewed on Apr 25, 2026

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Days Inn & Suites by Wyndham Morris/I-80
Hampton Inn Yorkville

Hampton Inn Yorkville

2.5 out of 5
310 East Countryside Parkway Yorkville IL
Book a stay at this business-friendly hotel in Yorkville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (931 reviews)
Wonderful hotel, reasonably priced, great breakfast.

Reviewed on Apr 24, 2026

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Hampton Inn Yorkville
Best Western Oglesby Inn

Best Western Oglesby Inn

2.5 out of 5
900 Holiday Street Oglesby IL
Book a stay at this business-friendly hotel in Oglesby. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.2/10 Very Good! (1,000 reviews)
I have stayed at Best Western Oglesby several times and have always been completely satisfied with the experience. The rooms and commons areas are clean, quiet and safe. The breakfast is always good and plentiful. And the staff are competent and pleasant. Highly recommend.

Reviewed on Apr 22, 2026

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Best Western Oglesby Inn
Holiday Inn Express & Suites Ottawa by IHG

Holiday Inn Express & Suites Ottawa by IHG

2.5 out of 5
2850 Columbus Street Ottawa IL
Book a stay at this business-friendly hotel in Ottawa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (575 reviews)
It was absolutely amazing the only downside which is not any of the staffs fault is that the fire alarm went off at about 3:30am but other than that it was a terrific stay and I will be back!

Reviewed on Apr 12, 2026

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Holiday Inn Express & Suites Ottawa by IHG
Comfort Inn Ottawa Starved Rock Area

Comfort Inn Ottawa Starved Rock Area

2.5 out of 5
120 W. Stevenson Road Ottawa IL
Book a stay at this business-friendly hotel in Ottawa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (806 reviews)
It was a wonderful say, very accommodating friendly staff, prep, friendly great with my kids and the hot tub was amazing

Reviewed on Apr 18, 2026

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Comfort Inn Ottawa Starved Rock Area
See all 344 properties in Serena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.