Hotels Near
Esquilino

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Featured Esquilino Hotels

Napoleon Hotel

Napoleon Hotel

4 out of 5
Piazza Vittorio Emanuele II 105 Rome RM
Fully refundableReserve now, pay when you stay
Stay at this hotel in Rome. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.6/10 Excellent! (1,015 reviews)
"The staff is wonderful and so helpful with anything you need. Room is very basic and tv super small. Toilet a little tricky but all else good. Good location cery close to colosseum and many sites. Quick taxi or train rise to airport."

Reviewed on Jun 8, 2026

Napoleon Hotel
Hotel Palladium Palace

Hotel Palladium Palace

4 out of 5
Via Gioberti 36 Rome RM
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Rome. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.2/10 Very Good! (972 reviews)
"This was not at all what we expected. The employee at the front desk was rude and completely unwelcoming. The room turned out to be very small. I do not recommend anyone stay at this hotel."

Reviewed on Jun 3, 2026

Hotel Palladium Palace
Rome Experience Hostel

Rome Experience Hostel

Via Statilia 31 Rome RM
Stay at this guesthouse in Rome. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Popular attractions Colosseum and Roman Forum are located ...
6.4/10 (152 reviews)
"The hostel has a great location and a nice terrace, which were definitely the highlights of my stay. The lady at the reception was very friendly and helpful, but unfortunately she seemed to be handling everything on her own. It is clear that one person cannot manage all the tasks alone. The main ..."

Reviewed on Jun 6, 2026

Rome Experience Hostel
The Cross Hotel

The Cross Hotel

3 out of 5
Via S.Croce in Gerusalemme, 40 Rome RM
Stay at this hotel in Rome. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (528 reviews)
"The hotel is in a great location. Right on the river with a classic view of the Tower Bridge. The staff from Checkin to Checkout was amazing. Our room was very clean and comfortable. Perhaps a bit careworn but it certainly met our expectation. We travel frequently; so I will say we would choose this ..."

Reviewed on Jun 7, 2026

The Cross Hotel
NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento

5 out of 5
Piazza Dei Cinquecento, 90 Rome RM
Book a stay at this luxury hotel in Rome. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and the property ...
9/10 Wonderful! (1,000 reviews)
"Very friendly!"

Reviewed on May 24, 2026

NH Collection Roma Palazzo Cinquecento
Hotel Terminal

Hotel Terminal

3 out of 5
Via Principe Amedeo 103 Rome RM
Fully refundableReserve now, pay when you stay
Stay at this hotel in Rome. Enjoy free WiFi, a 24-hour front desk, and an airport shuttle (surcharge). Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (406 reviews)
"The people were extremely friendly and helpful. Felt like home. Clean, room always tidy when we got back at night. Highly recommend"

Reviewed on May 29, 2026

Hotel Terminal
Hotel Valentino Palace

Hotel Valentino Palace

3 out of 5
Via Filippo Turati, 34 Rome RM
Stay at this hotel in Rome. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
7.8/10 Good! (475 reviews)
"Great location, handy to Termini Station. No coffee/tea making facilities in room."

Reviewed on Jun 8, 2026

Hotel Valentino Palace
Hotel Maryelen

Hotel Maryelen

2 out of 5
Via Principe Amedeo 85/a Rome RM
Stay at this hotel in Rome. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
Hotel Maryelen
Casa per Ferie Domus Helena

Casa per Ferie Domus Helena

Via Ferruccio, 25 Rome RM
Fully refundableReserve now, pay when you stay
Stay at this guesthouse in Rome. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.4/10 Exceptional! (484 reviews)
"J'ai aimé le côté moderne et tout ce qu'on a besoin mais l'accueil a été un peu bizzarre...l'employé n'était pas à son poste donc il.a fallu patienter un bon 15 min. et une chance qu'un autre client m'a ouvert la porte pour me faire entrer avec la chaleur qu'il y avait..aussi quelque chose bizzarre, ..."

Reviewed on Jun 8, 2026

Casa per Ferie Domus Helena
Hotel Agorà

Hotel Agorà

Via Marsala 80 Rome RM
Fully refundableReserve now, pay when you stay
Stay at this B&B in Rome. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.2/10 Good! (630 reviews)
"La ubicación"

Reviewed on Jun 6, 2026

Hotel Agorà
Villa Luzzatti Hostel

Villa Luzzatti Hostel

Via Luigi Luzzatti, 25 Rome RM
Stay at this guesthouse in Rome. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Popular attractions Colosseum and Roman Forum are located ...
5/10 (43 reviews)
"No bells and whistles, but it’s what you get what you pay great for the price"

Reviewed on Jun 5, 2026

Villa Luzzatti Hostel
Hotel Aphrodite

Hotel Aphrodite

4 out of 5
Via Marsala 90 Rome RM
Fully refundableReserve now, pay when you stay
Stay at this hotel in Rome. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
7.8/10 Good! (1,002 reviews)
"The hotel was right across from the train station. It was perfect for our need to stay overnight and catch the train to the airport the next day. Breakfast was fine. Room was clean and comfortable. Area was busy but hotel was not noisy."

Reviewed on Jun 1, 2026

Hotel Aphrodite
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Esquilino

Rome is a city that has a lot going on, but you have your sights set on Esquilino. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Esquilino has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Esquilino hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Rome so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Esquilino underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Esquilino city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Esquilino cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Esquilino at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $83
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Esquilino hotel you want, book it, and never look back. Because your great escape is ahead of you.