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Hotels in Florence

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Choose from 290 Florence Hotel Deals

Desert Reef Hot Springs

Desert Reef Hot Springs

2 out of 5
1194 Co Rd 110 Florence CO
  • 7 min drive from USP Florence ADX
Stay at this hotel in Florence. Enjoy free parking, hot springs on site, and a gift shop. Popular attractions Dakota Hot Springs and Pioneer Park are located ...
9.4/10 Exceptional! (9 reviews)
Desert Reef is a a quaint relaxing stay, soaking is very nice with shallow pools. We stayed in an Airstream our whole experience was phenomenal.

Reviewed on Sep 29, 2025

Desert Reef Hot Springs
Florence Vacation Rental w/ Rooftop Deck!

Florence Vacation Rental w/ Rooftop Deck!

3.5 out of 5
Florence CO
  • 6 min drive from USP Florence ADX
Book a stay at this family-friendly apartment in Florence. Enjoy free parking, an in-room coffeemaker, and air conditioning. Popular attractions Florence Pioneer ...
Beautiful place. Very clean. We would definitely stay there again if ever in CO again.

Reviewed on Nov 22, 2024

Florence Vacation Rental w/ Rooftop Deck!
Extended Stay America Premier Suites - Pueblo

Extended Stay America Premier Suites - Pueblo

2.5 out of 5
6020 North Elizabeth St Pueblo CO
  • 1 hour drive from USP Florence ADX
Book a stay at this business-friendly hotel in Pueblo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cinemark Tinseltown Pueblo and ...
8.8/10 Excellent! (417 reviews)
The room was amazing! The staff was excellent! Diamond in the rough!

Reviewed on Jan 3, 2026

Extended Stay America Premier Suites - Pueblo
Holiday Inn Express & Suites Canon City by IHG

Holiday Inn Express & Suites Canon City by IHG

2.5 out of 5
3271 HWY 50 Canon City CO
  • 19 min drive from USP Florence ADX
Book a stay at this business-friendly hotel in Canon City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (785 reviews)
Great stay

Reviewed on Jan 2, 2026

Holiday Inn Express & Suites Canon City by IHG
Quality Inn & Suites West

Quality Inn & Suites West

2.5 out of 5
77 South Radnor Dr Pueblo CO
  • 48 min drive from USP Florence ADX
Stay at this hotel in Pueblo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Desert ...
8.4/10 Very Good! (979 reviews)
Food was your standard quick breakfast options, staff was quiet, but fine. Rooms were clean, AC worked. Only bummer was no elevator and their inside pool/spa was closed

Reviewed on Dec 28, 2025

Quality Inn & Suites West
Best Western Canon City

Best Western Canon City

2.5 out of 5
110 Latigo Lane Canon City CO
  • 19 min drive from USP Florence ADX
Book a stay at this business-friendly hotel in Canon City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,001 reviews)
Room was clean and spacious.

Reviewed on Dec 30, 2025

Best Western Canon City
Hampton Inn Canon City

Hampton Inn Canon City

2.5 out of 5
102 Mccormick Pkwy Canon City CO
  • 19 min drive from USP Florence ADX
Stay at this hotel in Canon City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.8/10 (1,000 reviews)
Lean rooms. Breakfast was decent.

Reviewed on Dec 29, 2025

Hampton Inn Canon City
Parkview Inn Motel

Parkview Inn Motel

2 out of 5
231 Royal Gorge Blvd. Canon City CO
  • 23 min drive from USP Florence ADX
Stay at this motel in Canon City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (1,001 reviews)
Neat room with plenty of space for our family. Loved the location of our room.

Reviewed on Dec 21, 2025

Parkview Inn Motel
Hampton Inn & Suites Pueblo/North

Hampton Inn & Suites Pueblo/North

2.5 out of 5
4790 Eagleridge Circle Pueblo CO
  • 1 hour drive from USP Florence ADX
Stay at this hotel in Pueblo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Cinemark ...
8.6/10 Excellent! (1,001 reviews)
Was still needing remodeling finished. Mattress needs updated still. Cleanliness was less than satisfactory.

Reviewed on Jan 1, 2026

Hampton Inn & Suites Pueblo/North
Budget Host Royal Gorge Inn

Budget Host Royal Gorge Inn

2 out of 5
217 N Raynolds Ave Canon City CO
  • 21 min drive from USP Florence ADX
Stay at this motel in Canon City. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.4/10 Very Good! (328 reviews)
The room was spotless as usual! We always love seeing David! He is super kind and polite! We stay here everytime we are in town!

Reviewed on Dec 14, 2025

Budget Host Royal Gorge Inn
Days Inn by Wyndham Canon City

Days Inn by Wyndham Canon City

2 out of 5
311 Royal Gorge Blvd Canon City CO
  • 23 min drive from USP Florence ADX
Book a stay at this business-friendly hotel in Canon City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7/10 Good! (1,000 reviews)
Clean ,hot indoor pool ,good breakfast, great staff

Reviewed on Jan 3, 2026

Days Inn by Wyndham Canon City
avid hotel Pueblo North by IHG

avid hotel Pueblo North by IHG

2 out of 5
855 Eagleridge Boulevard Pueblo CO
  • 1 hour drive from USP Florence ADX
Stay at this hotel in Pueblo. Enjoy free breakfast, free parking, and a 24-hour fitness center. Popular attractions Cinemark Tinseltown Pueblo and Greenhorn ...
9/10 Wonderful! (145 reviews)
This hotel was amazing. My partner and I drove 16 hours and were exhausted, we saw avid hotel and from reviews it seemed like the cleanest and safest location. I was weary at check in as reviews from other locations stated rude workers but I was greeted my the nicest lady. I may not have made sense ...

Reviewed on Jan 3, 2026

avid hotel Pueblo North by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Florence

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Frequently Asked Questions About Florence hotels

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How many hotels are there in Florence?

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