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Hotels in Florence

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Choose from 290 Florence Hotel Deals

Desert Reef Hot Springs

Desert Reef Hot Springs

2 out of 5
1194 Co Rd 110, Florence, CO
  • 7 min drive from USP Florence ADX
Stay at this hotel in Florence. Enjoy free parking, hot springs on site, and a gift shop. Popular attractions Dakota Hot Springs and Pioneer Park are located ...
9.4/10 Exceptional! (9 reviews)
"Desert Reef is a a quaint relaxing stay, soaking is very nice with shallow pools. We stayed in an Airstream our whole experience was phenomenal."

Reviewed on Sep 29, 2025

Desert Reef Hot Springs
Arkansas Avenue

Arkansas Avenue

3 out of 5
626 E 3rd St, Florence, CO
  • 6 min drive from USP Florence ADX
Stay at this 3-star vacation home in Florence. Enjoy free WiFi, free parking, and a garden. Popular attractions Pioneer Park and Florence Pioneer Museum are ...
Arkansas Avenue
Budget Host Royal Gorge Inn

Budget Host Royal Gorge Inn

2 out of 5
217 N Raynolds Ave, Canon City, CO
  • 21 min drive from USP Florence ADX
Stay at this motel in Canon City. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.2/10 Very Good! (299 reviews)
"The property is a bit dated, but it is very clean and quiet with an exceptional staff."

Reviewed on Oct 6, 2025

Budget Host Royal Gorge Inn
Days Inn by Wyndham Canon City

Days Inn by Wyndham Canon City

2 out of 5
311 Royal Gorge Blvd, Canon City, CO
  • 23 min drive from USP Florence ADX
Book a stay at this business-friendly hotel in Canon City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7/10 Good! (1,004 reviews)
"Breakfast was skimpy. No fruit. Only waffles and toast. No butter, no juice, no milk"

Reviewed on Oct 13, 2025

Days Inn by Wyndham Canon City
Holiday Inn Express & Suites Canon City by IHG

Holiday Inn Express & Suites Canon City by IHG

2.5 out of 5
3271 HWY 50, Canon City, CO
  • 19 min drive from USP Florence ADX
Book a stay at this business-friendly hotel in Canon City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (729 reviews)
"Very clean, new looking. Very comfortable."

Reviewed on Oct 11, 2025

Holiday Inn Express & Suites Canon City by IHG
Parkview Inn Motel

Parkview Inn Motel

2 out of 5
231 Royal Gorge Blvd., Canon City, CO
  • 23 min drive from USP Florence ADX
Stay at this motel in Canon City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (1,007 reviews)
"Plenty of parking. Our room has a full, queen, and a twin bed. The water pressure is strong, friendly staff. I lost my DL but they still allowing me to stay the night. The location is quite close to Royal Gorge Train if you wanna book the place."

Reviewed on Oct 11, 2025

Parkview Inn Motel
Best Western Canon City

Best Western Canon City

2.5 out of 5
110 Latigo Lane, Canon City, CO
  • 19 min drive from USP Florence ADX
Book a stay at this business-friendly hotel in Canon City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,000 reviews)
"Good Hotel"

Reviewed on Oct 12, 2025

Best Western Canon City
Quality Inn & Suites Canon City

Quality Inn & Suites Canon City

2.5 out of 5
3075 E US 50, Canon City, CO
  • 20 min drive from USP Florence ADX
Book a stay at this family-friendly hotel in Canon City. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the breakfast and the helpful ...
7/10 Good! (877 reviews)
"Great place. Clean, comfortable beds, reasonable rate"

Reviewed on Oct 13, 2025

Quality Inn & Suites Canon City
Quality Inn & Suites West

Quality Inn & Suites West

2.5 out of 5
77 South Radnor Dr, Pueblo, CO
  • 48 min drive from USP Florence ADX
Stay at this hotel in Pueblo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Desert ...
8.4/10 Very Good! (939 reviews)
"Great place"

Reviewed on Sep 28, 2025

Quality Inn & Suites West
Comfort Inn & Suites Pueblo

Comfort Inn & Suites Pueblo

2.5 out of 5
3910 Outlook Blvd, Pueblo, CO
  • 1 hour drive from USP Florence ADX
Book a stay at this business-friendly hotel in Pueblo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (874 reviews)
"Very comfortable room. We stayed at this hotel on our way to Omaha and on our back home. Very nice place"

Reviewed on Sep 27, 2025

Comfort Inn & Suites Pueblo
Hampton Inn Canon City

Hampton Inn Canon City

2.5 out of 5
102 Mccormick Pkwy, Canon City, CO
  • 19 min drive from USP Florence ADX
Stay at this hotel in Canon City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.8/10 (1,016 reviews)
"Clean comfortable room. Unfortunately no hot breakfast due to broken oven, but yogurt and bagels were good."

Reviewed on Oct 11, 2025

Hampton Inn Canon City
Royal Gorge Cabins

Royal Gorge Cabins

3.5 out of 5
45054 West US Hwy 50, Canon City, CO
  • 36 min drive from USP Florence ADX
Stay at this 3.5-star cabin in Canon City. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Royal Gorge Bridge and Tunnel Drive are ...
9.6/10 Exceptional! (243 reviews)
"Very clean and close to great experiences!"

Reviewed on Oct 13, 2025

Royal Gorge Cabins
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Florence

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $58. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Florence hotel deals at the last minute.

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Frequently Asked Questions About Florence hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Florence?

With over 290 hotels in Florence, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $58.

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Finding a cheap car rental deal in Florence is as easy as scoring cheap hotels in Florence. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.