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Choose from 58 Florence Hotel Deals

Creek Views & Grill: Idyllic Florence Cabin

Creek Views & Grill: Idyllic Florence Cabin

3 out of 5
Florence MO
  • 1 hour drive from Lake of the Ozarks
Stay at this cottage in Florence. Enjoy free parking, an in-room coffeemaker, and air conditioning.
10/10 Exceptional! (2 reviews)
"Beautiful little cabin. Nice clean Creek 20' from the door. Wish I had brought a fishing rod. And a little sweet treat the host left for me was a welcoming surprise. Highly recommend, I will book again."

Reviewed on May 3, 2026

Creek Views & Grill: Idyllic Florence Cabin
Florence Cabin w/ On-site Creek!

Florence Cabin w/ On-site Creek!

3 out of 5
Florence MO
  • 1 hour drive from Lake of the Ozarks
Book a stay at this business-friendly cottage in Florence. Enjoy free parking, an in-room coffeemaker, and air conditioning.
10/10 Exceptional! (1 review)
Big rock
"Hands down the best, cleanest and cutest cabin we have ever stayed in! All everyday household items included and the friendliest owners. I highly recommend a stay at this cabin rental. Extremely satisfied!"

Reviewed on Aug 17, 2025

Florence Cabin w/ On-site Creek!
Goats On-site! Unique Creekside Escape in Ozarks

Goats On-site! Unique Creekside Escape in Ozarks

3 out of 5
Florence MO
  • 1 hour drive from Lake of the Ozarks
Stay at this cottage in Florence. Enjoy free parking and air conditioning.
Goats On-site! Unique Creekside Escape in Ozarks
Econo Lodge Truman Inn

Econo Lodge Truman Inn

2 out of 5
3501 W Broadway Blvd Sedalia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Sedalia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Daum Museum of Contemporary Art ...
5.8/10 (794 reviews)
"Room was clean but dated and in need of some repairs. Hallways were a bit musty."

Reviewed on May 21, 2026

Econo Lodge Truman Inn
Comfort Inn Sedalia Station

Comfort Inn Sedalia Station

2.5 out of 5
3600 W Broadway Blvd Sedalia MO
  • 2 hours drive from Lake of the Ozarks
Stay at this hotel in Sedalia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (628 reviews)
"Clean room"

Reviewed on May 14, 2026

Comfort Inn Sedalia Station
Best Western State Fair Inn

Best Western State Fair Inn

3 out of 5
3120 S Limit Sedalia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Sedalia. Enjoy free breakfast, free parking, and room service. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (808 reviews)
"Clean room"

Reviewed on May 20, 2026

Best Western State Fair Inn
Holiday Inn Express & Suites Sedalia by IHG

Holiday Inn Express & Suites Sedalia by IHG

2.5 out of 5
4001 W Broadway Blvd Sedalia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Sedalia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (610 reviews)
"Good place, nice steak house next door. Would stay again. Breakfast was just ok."

Reviewed on May 21, 2026

Holiday Inn Express & Suites Sedalia by IHG
Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel

Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel

3 out of 5
103 E 4th St Sedalia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Sedalia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (615 reviews)
"Amazing experience! Service was above and beyond and the room was spotless."

Reviewed on May 21, 2026

Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel
Motel 6 Sedalia, MO

Motel 6 Sedalia, MO

2 out of 5
3402 W Broadway Blvd Sedalia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly motel in Sedalia. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. ...
5.6/10 (700 reviews)
"we chose to stay at Motel 6 to save $$. had a king room, bed very comfortable, and the bathroom was very nice, looked remodeled. No complaints."

Reviewed on May 21, 2026

Motel 6 Sedalia, MO
Hampton Inn Sedalia

Hampton Inn Sedalia

2.5 out of 5
3909 West 9th Street Sedalia MO
  • 2 hours drive from Lake of the Ozarks
Stay at this hotel in Sedalia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Daum ...
Hampton Inn Sedalia
Super 7 Motel Sedalia

Super 7 Motel Sedalia

2.5 out of 5
5650 S Limit Ave Sedalia MO
  • 2 hours drive from Lake of the Ozarks
Stay at this motel in Sedalia. Enjoy free WiFi, free parking, and room service. Popular attractions Leisure Park and Missouri State Fairgrounds are located ...
6.2/10 (335 reviews)
"My stay was awful and I didn’t not stay the whole 3 days, first we requested a non smoking room but the room had been smoked in, the walls had scuffs and some kind of stain on them, the bathroom looked like it hasn’t been cleaned since the place opened, there was throw up in the floor and on the ..."

Reviewed on May 12, 2026

Super 7 Motel Sedalia
Hawthorne Inn

Hawthorne Inn

2 out of 5
206 E Jasper St Versailles MO
  • 49 min drive from Lake of the Ozarks
Stay at this B&B in Versailles. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Jacob's Cave is located nearby.
Hawthorne Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Florence

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Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Florence’s 58 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $56. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Florence hotel deals at the last minute.

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Frequently Asked Questions About Florence hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Florence for as low as $56.

How many hotels are there in Florence?

With over 58 hotels in Florence, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $56.

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Finding a cheap car rental deal in Florence is as easy as scoring cheap hotels in Florence. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.