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Choose from 66 Florence Hotel Deals
Creek Views & Grill: Idyllic Florence Cabin
"Great place to stay plan to stay here again!"
Reviewed on Aug 23, 2026
Florence Cabin w/ On-site Creek!
"Hands down the best, cleanest and cutest cabin we have ever stayed in! All everyday household items included and the friendliest owners. I highly recommend a stay at this cabin rental. Extremely satisfied!"
Reviewed on Aug 17, 2025
Goats On-site! Unique Creekside Escape in Ozarks
"Clean and comfortable. Did have to drive on 2 miles of gravel. Loved being by the creek. Too hot for fire pit but very nice."
Reviewed on Aug 21, 2026
Econo Lodge Truman Inn
Motel 6 Sedalia, MO
Comfort Inn Sedalia Station
"Affordable but a bit outdated. Musty smelling. Clean linens and a great mattress. Breakfast was nice, plenty of options. Probably as good as it gets in rural Missouri."
Reviewed on Sep 1, 2026
American Inn Sedalia
"The property was clean, neat and we had everything we needed. We chose this because it did not have amenities and we did not want them. We needed a place to sleep and shower. Had fridge & microwave. No coffee in room or pool or weight room. Room was quiet and had AC. Location was good. Was between ..."
Reviewed on Sep 2, 2026
Holiday Inn Express & Suites Sedalia by IHG
Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel
Best Western State Fair Inn
"Check in was easy, front desk personnel was very helpful. Show me to my room and helped me find directions to my destination."
Reviewed on Aug 30, 2026
Super 7 Motel Sedalia
"We booked our trip for the state fair. We checked in shortly before midnight. Got to our room, turned on the light and baby bugs scattered everywhere! They were baby ROACHES!! Crawling all over the top of the dresser. Not to mention when we got to the room it was so hot, the air had not been turned ..."
Reviewed on Sep 3, 2026
Budget Inn
"the room was clean, the amenities were well marked and the staff obviously cares about the appearance if the rooms. the towels, washcloths, etc. we're "fancy folded". the staff truly presents a quality room."
Reviewed on Aug 29, 2026
Find cheap hotels in Florence
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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Florence.
Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Florence’s 66 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $62. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Florence hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Florence. No matter your reason for visiting Florence, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About Florence hotels
Where can I find the best last-minute travel deals?
If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Florence for as low as $62.
How many hotels are there in Florence?
With over 66 hotels in Florence, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $62.
How to find cheap car rentals in Florence?
Finding a cheap car rental deal in Florence is as easy as scoring cheap hotels in Florence. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.
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