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Hotels in Central Missouri

Choose from 4751 Central Missouri Hotel Deals

Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

2.5 out of 5
2601 S Providence Rd Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.4/10 Very Good! (1,370 reviews)
Very nice staff, clean room

Reviewed on Feb 12, 2026

Stoney Creek Hotel Columbia
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

3 out of 5
3100 Interstate 70 Dr. SE Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,364 reviews)
Great Staff and overall great experience

Reviewed on Feb 12, 2026

Drury Plaza Hotel Columbia East
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

2.5 out of 5
817 N Keene St Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,732 reviews)
Clean room. Staff courteous. Large room.

Reviewed on Feb 7, 2026

Country Inn & Suites by Radisson, Columbia, MO
Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks

3 out of 5
494 Tan Tar A Drive Osage Beach MO
  • 14 min drive from Lake of the Ozarks
Book a stay at this spa resort in Osage Beach. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,001 reviews)
Room was clean, friendly staff, so much fun stuff to do. The restaurant in the lounge was incredible. We will definitely be staying here again.

Reviewed on Feb 13, 2026

Margaritaville Lake Resort Lake of the Ozarks
Baymont by Wyndham Jefferson City

Baymont by Wyndham Jefferson City

2.5 out of 5
319 W. Miller Street Jefferson City MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Jefferson City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,002 reviews)
The hotel is very clean, breakfast is nice only issue is the bed was not comfortable for me a little firm. Overall a great hotel.

Reviewed on Feb 14, 2026

Baymont by Wyndham Jefferson City
Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa

4 out of 5
315 Four Seasons Dr. Lake Ozark MO
  • 20 min drive from Lake of the Ozarks
Book a stay at this beach resort in Lake Ozark. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in ...
7.4/10 Good! (1,099 reviews)
Great stay

Reviewed on Feb 12, 2026

Lodge Of Four Seasons Golf Resort, Marina & Spa
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

3 out of 5
3101 Wingate Ct Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,236 reviews)
Staff was easy to work with, comfortable bed and clean room.

Reviewed on Feb 8, 2026

Wingate by Wyndham - Columbia
Wyndham Executive Center Columbia

Wyndham Executive Center Columbia

3.5 out of 5
2200 I-70 Drive SW Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,002 reviews)
Clean great staff. They have a bar!!

Reviewed on Feb 3, 2026

Wyndham Executive Center Columbia
Best Western Plus Columbia Inn

Best Western Plus Columbia Inn

2.5 out of 5
2904 Clark Lane Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,237 reviews)
It was a 10 out of 10

Reviewed on Feb 10, 2026

Best Western Plus Columbia Inn
Drury Inn & Suites Columbia Stadium Boulevard

Drury Inn & Suites Columbia Stadium Boulevard

3 out of 5
1000 Knipp St Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,000 reviews)
Service was very good. Staff was helpful and friendly.

Reviewed on Feb 9, 2026

Drury Inn & Suites Columbia Stadium Boulevard
Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

2.5 out of 5
2500 I 70 Dr Sw Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
8.2/10 Very Good! (661 reviews)
Room was clean and thr bed was comfortable. Didn't try the.breakfasy. Left at 5:45. The shooter was the forefathers ..lukewarm.

Reviewed on Feb 4, 2026

Baymont by Wyndham Columbia, MO
The Broadway Columbia - a DoubleTree by Hilton

The Broadway Columbia - a DoubleTree by Hilton

4 out of 5
1111 E Broadway Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.2/10 Wonderful! (955 reviews)
The Broadmo

Reviewed on Feb 2, 2026

The Broadway Columbia - a DoubleTree by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Central Missouri

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Central Missouri.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Central Missouri’s 4,751 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $72. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Central Missouri hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Central Missouri. No matter your reason for visiting Central Missouri, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Central Missouri hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Central Missouri for as low as $72.

How many hotels are there in Central Missouri?

With over 4,751 hotels in Central Missouri, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $72.

How to find cheap car rentals in Central Missouri?

Finding a cheap car rental deal in Central Missouri is as easy as scoring cheap hotels in Central Missouri. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.