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Hotels in Central Missouri

Choose from 4907 Central Missouri Hotel Deals

Capitol Plaza Hotel Jefferson City

Capitol Plaza Hotel Jefferson City

3.5 out of 5
Jefferson City 415 W. McCarty St Jefferson City MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Jefferson City. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff ...
7/10 Good! (1,008 reviews)
The hotel is getting old but the rooms have been updated and are clean and comfortable. Only 1 elevator was working . No hot water, only luke warm, in the afternoon. Good location for the Katy Trail.

Reviewed on Mar 22, 2026

Capitol Plaza Hotel Jefferson City
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

2.5 out of 5
817 N Keene St Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,764 reviews)
Very clean as always

Reviewed on Mar 22, 2026

Country Inn & Suites by Radisson, Columbia, MO
Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

2.5 out of 5
2601 S Providence Rd Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.6/10 Excellent! (1,376 reviews)
The hotel theme is a cute idea however, as other guests have mentioned, it needs updated. Rooms are large. Needs to be deep cleaned more frequently. Carpet around the perimeter of the room is dirty. The water gets scalding hot which scared me having a two year old. The beds were ok but the headboard ...

Reviewed on Mar 22, 2026

Stoney Creek Hotel Columbia
Wyndham Executive Center Columbia

Wyndham Executive Center Columbia

3.5 out of 5
2200 I-70 Drive SW Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,011 reviews)
The room was out dated.

Reviewed on Mar 23, 2026

Wyndham Executive Center Columbia
Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

2.5 out of 5
2500 I 70 Dr Sw Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
8.2/10 Very Good! (707 reviews)
Nice friendly staff.

Reviewed on Mar 23, 2026

Baymont by Wyndham Columbia, MO
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

3 out of 5
3100 Interstate 70 Dr. SE Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,399 reviews)
The AC did not cool down at first but was fixed after I said something and came back later that night

Reviewed on Mar 23, 2026

Drury Plaza Hotel Columbia East
Best Western Plus Columbia Inn

Best Western Plus Columbia Inn

2.5 out of 5
2904 Clark Lane Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,268 reviews)
Our room smelled like a wet dog and stinky feet. When i booked the room, i booked a double queen room but we got a king and a pull out couch room. We did not get pillows for the pull out couch. The pool was so cold my kids did not want to swim.

Reviewed on Mar 23, 2026

Best Western Plus Columbia Inn
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

3 out of 5
3101 Wingate Ct Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,225 reviews)
Everything was clean and welcoming. Breakfast was hot and delicious perfect for a couple of grandparents in town for ball tournaments.

Reviewed on Mar 22, 2026

Wingate by Wyndham - Columbia
Inn at Grand Glaize

Inn at Grand Glaize

2 out of 5
5142 Osage Beach Pkwy Osage Beach MO
  • 24 min drive from Lake of the Ozarks
Book a stay at this golf hotel in Osage Beach. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in ...
7.4/10 Good! (273 reviews)
Nice place to say but go out to eat

Reviewed on Mar 22, 2026

Inn at Grand Glaize
Days Inn by Wyndham Rolla

Days Inn by Wyndham Rolla

2.5 out of 5
2006 N Bishop Ave Rolla MO
  • 3 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Rolla. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,005 reviews)
Contintal breafast was crap. Everthing else 5 stars

Reviewed on Mar 23, 2026

Days Inn by Wyndham Rolla
Ramada by Wyndham Columbia

Ramada by Wyndham Columbia

2.5 out of 5
901 Conley Rd Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,004 reviews)
Honestly it was great. The staff was very accommodating and the room was very nice for what we paid. I wish more hotels in Columbia allowed dogs but so grateful they do.

Reviewed on Mar 23, 2026

Ramada by Wyndham Columbia
Quality Inn & Suites Columbia I-70

Quality Inn & Suites Columbia I-70

2.5 out of 5
801 Keene St Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (857 reviews)
The quality of the room was horrible. There were holes in the curtains and the sheets. Had a mildew smell in the room. Seen a few bugs throughout the hotel. There was not a good variety of food for breakfast.

Reviewed on Mar 22, 2026

Quality Inn & Suites Columbia I-70
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Central Missouri

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Central Missouri.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Central Missouri’s 4,907 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $70. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Central Missouri hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Central Missouri. No matter your reason for visiting Central Missouri, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Central Missouri hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Central Missouri for as low as $70.

How many hotels are there in Central Missouri?

With over 4,907 hotels in Central Missouri, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $70.

How to find cheap car rentals in Central Missouri?

Finding a cheap car rental deal in Central Missouri is as easy as scoring cheap hotels in Central Missouri. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.