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Hotels in Central Missouri

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Choose from 5123 Central Missouri Hotel Deals

Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa

4 out of 5
315 Four Seasons Dr. Lake Ozark MO
  • 20 min drive from Lake of the Ozarks
Book a stay at this beach resort in Lake Ozark. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in ...
7.4/10 Good! (1,147 reviews)
"Manager is excellent!"

Reviewed on Jun 7, 2026

Lodge Of Four Seasons Golf Resort, Marina & Spa
Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks

3 out of 5
494 Tan Tar A Drive Osage Beach MO
  • 14 min drive from Lake of the Ozarks
Book a stay at this spa resort in Osage Beach. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the clean rooms in ...
8.4/10 Very Good! (1,005 reviews)
"Staff wonderful, a/c didn't work properly in room and toilet ran constantly. Staff was very helpful and compensating. Property outside of room 5 star. Rooms 3.5 star."

Reviewed on Jun 3, 2026

Margaritaville Lake Resort Lake of the Ozarks
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

4 out of 5
3100 Interstate 70 Dr. SE Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,468 reviews)
"Appreciated access to pull through parking spots as we were towing a trailer. Reasonable pet fee. Great breakfast selection."

Reviewed on Jun 6, 2026

Drury Plaza Hotel Columbia East
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

3 out of 5
3101 Wingate Ct Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,248 reviews)
"Very clean and comfortable. They even had water in the gym. Breakfast was also good."

Reviewed on Jun 6, 2026

Wingate by Wyndham - Columbia
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

2.5 out of 5
817 N Keene St Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,867 reviews)
"amazing staff room was clean"

Reviewed on Jun 7, 2026

Country Inn & Suites by Radisson, Columbia, MO
Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

2.5 out of 5
2601 S Providence Rd Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.6/10 Excellent! (1,381 reviews)
"Hotel needs better maintenance, really old . It had lots of potential to be great because of the cool themes and location . Need to replace beds as well . It was ok if you want a budged friendly option."

Reviewed on Jun 6, 2026

Stoney Creek Hotel Columbia
Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

2.5 out of 5
2500 I 70 Dr Sw Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
8.2/10 Very Good! (830 reviews)
"The lady with blonde hair that was at the desk. Was very rude"

Reviewed on Jun 5, 2026

Baymont by Wyndham Columbia, MO
Wyndham Executive Center Columbia

Wyndham Executive Center Columbia

3.5 out of 5
2200 I-70 Drive SW Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,014 reviews)
"Excellent staff, batteries went out in thermostat and got hot in room and front desk immediately found batteries and came to the room and replaced them at almost 1 in the morning. Pool was a little chilly inside but outside pool was clean and warm."

Reviewed on Jun 7, 2026

Wyndham Executive Center Columbia
The Resort at Lake of the Ozarks

The Resort at Lake of the Ozarks

3 out of 5
3080 Bagnell Dam Blvd Lake Ozark MO
  • 29 min drive from Lake of the Ozarks
Book a stay at this golf resort in Lake Ozark. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the helpful staff in our reviews. ...
8/10 Very Good! (620 reviews)
"The view was beautiful at the water,but the grounds were not kept up. Weeds everywhere. Indoor pool not clean. Breakfast was minimal."

Reviewed on Jun 7, 2026

The Resort at Lake of the Ozarks
Inn at Grand Glaize

Inn at Grand Glaize

2 out of 5
5142 Osage Beach Pkwy Osage Beach MO
  • 24 min drive from Lake of the Ozarks
Book a stay at this golf hotel in Osage Beach. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in ...
7.4/10 Good! (321 reviews)
"Outdated"

Reviewed on Jun 6, 2026

Inn at Grand Glaize
Ramada by Wyndham Columbia

Ramada by Wyndham Columbia

2.5 out of 5
901 Conley Rd Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,011 reviews)
"Nice room. But we ran out of hot water at the end of my shower. My husband had none. The guy came up and checked it out. We were told to wait it would get hot later."

Reviewed on Jun 7, 2026

Ramada by Wyndham Columbia
Schmidt's Creek Hotel

Schmidt's Creek Hotel

2 out of 5
5760 Osage Beach Pkwy Osage Beach MO
  • 20 min drive from Lake of the Ozarks
Book a stay at this golf hotel in Osage Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (524 reviews)
"It was very good. Easy to check in. Parking lot was a little hard to get out, but I was able to park in front of my room. Definitely will be staying there again."

Reviewed on Jun 7, 2026

Schmidt's Creek Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Central Missouri

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Frequently Asked Questions About Central Missouri hotels

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How many hotels are there in Central Missouri?

With over 5,123 hotels in Central Missouri, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $67.

How to find cheap car rentals in Central Missouri?

Finding a cheap car rental deal in Central Missouri is as easy as scoring cheap hotels in Central Missouri. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.