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Hotels in Central Missouri

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Choose from 5159 Central Missouri Hotel Deals

Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa

4 out of 5
315 Four Seasons Dr. Lake Ozark MO
  • 20 min drive from Lake of the Ozarks
Book a stay at this beach resort in Lake Ozark. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in ...
7.4/10 Good! (1,194 reviews)
"There was roaches in our room. It wasn't cleaned well at all. Did not stay the night. Had to finf another hotel."

Reviewed on Jun 27, 2026

Lodge Of Four Seasons Golf Resort, Marina & Spa
Inn at Grand Glaize

Inn at Grand Glaize

2 out of 5
5142 Osage Beach Pkwy Osage Beach MO
  • 24 min drive from Lake of the Ozarks
Book a stay at this golf hotel in Osage Beach. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in ...
7.4/10 Good! (354 reviews)
"Good location. Staff was great. Very clean. We are going back in July hopefully we can enjoy the pool and other amenities. Can’t wait"

Reviewed on Jun 28, 2026

Inn at Grand Glaize
Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks

3 out of 5
494 Tan Tar A Drive Osage Beach MO
  • 14 min drive from Lake of the Ozarks
Book a stay at this spa resort in Osage Beach. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the clean rooms in ...
8.4/10 Very Good! (1,005 reviews)
"All staff was friendly and helpful!"

Reviewed on Jun 26, 2026

Margaritaville Lake Resort Lake of the Ozarks
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

4 out of 5
3100 Interstate 70 Dr. SE Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,502 reviews)
"Well maintained, helpful staff. Very quiet rooms even right next to highway."

Reviewed on Jun 28, 2026

Drury Plaza Hotel Columbia East
Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

2.5 out of 5
2500 I 70 Dr Sw Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
8.2/10 Very Good! (874 reviews)
"nice clean hotel with pretty good breakfast. Loved the pillows (often hotels have much harder pillows and I prefer a softer one). Only complaint would be about the shower head/water pressure not being as strong as I would like."

Reviewed on Jun 27, 2026

Baymont by Wyndham Columbia, MO
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

3 out of 5
3101 Wingate Ct Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,248 reviews)
"Amazing place to stay! I stayed from a long drive from New Mexico and I slept like a baby. Comfortable and big rooms, great beds, tasty breakfast and safe location. Totally recommend it!"

Reviewed on Jun 27, 2026

Wingate by Wyndham - Columbia
Schmidt's Creek Hotel

Schmidt's Creek Hotel

2 out of 5
5760 Osage Beach Pkwy Osage Beach MO
  • 20 min drive from Lake of the Ozarks
Book a stay at this golf hotel in Osage Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (550 reviews)
"The room was simple, but clean."

Reviewed on Jun 27, 2026

Schmidt's Creek Hotel
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

2.5 out of 5
817 N Keene St Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,893 reviews)
"Average property, nothing was poor or broken, some painting needed in some places. Staff did there standard job,nothing above and beyond,expect for housekeeping there was a flower toilet paper sheet. Breakfast was your standard hotel breakfast spread. Pool was clean and the hot tub was working, always ..."

Reviewed on Jun 27, 2026

Country Inn & Suites by Radisson, Columbia, MO
Capitol Plaza Hotel Jefferson City

Capitol Plaza Hotel Jefferson City

3.5 out of 5
Jefferson City 415 W. McCarty St Jefferson City MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Jefferson City. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff ...
7/10 Good! (1,010 reviews)
"The room was clean, but the hotel is becoming a bit dated. Some of the exterior areas need to be cleaned up as well. The breakfast was good and the staff were friendly."

Reviewed on Jun 27, 2026

Capitol Plaza Hotel Jefferson City
Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

2.5 out of 5
2601 S Providence Rd Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.6/10 Excellent! (1,381 reviews)
"We been staying stony creek and it's a awesome hotel to stay all stuff so helpful"

Reviewed on Jun 24, 2026

Stoney Creek Hotel Columbia
Best Western Plus Columbia Inn

Best Western Plus Columbia Inn

2.5 out of 5
2904 Clark Lane Columbia MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,343 reviews)
"Great place"

Reviewed on Jun 28, 2026

Best Western Plus Columbia Inn
Hotel Blu

Hotel Blu

2.5 out of 5
3402 Interstate 70 Dr SE Columbia MO
  • 2 hours drive from Lake of the Ozarks
Stay at this hotel in Columbia. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Mizzou Arena and Stephens Lake Park are located ...
7/10 Good! (55 reviews)
"The room smelled like really bad cleaner and the furniture was very worn and stained. It didn’t feel clean to sit anywhere but the hard chair."

Reviewed on Jun 28, 2026

Hotel Blu
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Central Missouri

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Frequently Asked Questions About Central Missouri hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Central Missouri?

With over 5,159 hotels in Central Missouri, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $68.

How to find cheap car rentals in Central Missouri?

Finding a cheap car rental deal in Central Missouri is as easy as scoring cheap hotels in Central Missouri. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.