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Hotels in Central Missouri

Choose from 4493 Central Missouri Hotel Deals

Baymont by Wyndham Columbia, MO
Baymont by Wyndham Columbia, MO
2.5 out of 5
2500 I 70 Dr Sw, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.8/10 Good! (242 reviews)
"Room was clean. Staff very friendly and helpful. Highway noise was very noticeable. Price on graduation was significantly inflated. I expected an increase, but it was much more than the physical property was worth."

Reviewed on May 17, 2025

Baymont by Wyndham Columbia, MO
Margaritaville Lake Resort Lake of the Ozarks
Margaritaville Lake Resort Lake of the Ozarks
3 out of 5
494 Tan Tar A Drive, Osage Beach, MO
  • 14 min drive from Lake of the Ozarks
Stay at this 3-star spa resort in Osage Beach. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,007 reviews)
"I stayed here for a school function for my son. To me the room is a bit overpriced since a lot of the amenities aren’t included. You still had to pay to use the waterpark, bowling alley and pool hall. I feel that with the price of the room being so high, these should have been included or at least ..."

Reviewed on May 16, 2025

Margaritaville Lake Resort Lake of the Ozarks
Lodge Of Four Seasons Golf Resort, Marina & Spa
Lodge Of Four Seasons Golf Resort, Marina & Spa
4 out of 5
315 Four Seasons Dr., Lake Ozark, MO
  • 20 min drive from Lake of the Ozarks
Stay at this 4-star beach resort in Lake Ozark. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in ...
7.2/10 Good! (1,009 reviews)
"The staff were very kind and accommodating,"

Reviewed on May 18, 2025

Lodge Of Four Seasons Golf Resort, Marina & Spa
Country Inn & Suites by Radisson, Columbia, MO
Country Inn & Suites by Radisson, Columbia, MO
2.5 out of 5
817 N Keene St, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,497 reviews)
"Good location, clean smelled good, breakfast was better than average…only complaint was that the staff was very matter a fact, not friendly or helpful. Just gave perfunctory answers when asked questions."

Reviewed on May 15, 2025

Country Inn & Suites by Radisson, Columbia, MO
Capitol Plaza Hotel Jefferson City
Capitol Plaza Hotel Jefferson City
3.5 out of 5
Jefferson City 415 W. McCarty St, Jefferson City, MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Jefferson City. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff ...
6.8/10 (1,024 reviews)
"Great place to stay"

Reviewed on May 14, 2025

Capitol Plaza Hotel Jefferson City
Stoney Creek Hotel Columbia
Stoney Creek Hotel Columbia
2.5 out of 5
2601 S Providence Rd, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.6/10 Excellent! (1,233 reviews)
"We love staying here for the convenience of the location vlose to campus and large parking lot and lota of dining options nearby."

Reviewed on May 16, 2025

Stoney Creek Hotel Columbia
Drury Plaza Hotel Columbia East
Drury Plaza Hotel Columbia East
3 out of 5
3100 Interstate 70 Dr. SE, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,135 reviews)
Great place to stay.
"Great place to stay! Excellent amenities, very clean, comfortable bed."

Reviewed on May 17, 2025

Drury Plaza Hotel Columbia East
Best Western Plus Columbia Inn
Best Western Plus Columbia Inn
2.5 out of 5
2904 Clark Lane, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,141 reviews)
"Na"

Reviewed on May 15, 2025

Best Western Plus Columbia Inn
Wingate by Wyndham - Columbia
Wingate by Wyndham - Columbia
3 out of 5
3101 Wingate Ct, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,091 reviews)
"I was in the area due to my son graduating college in Marshall,MO. Everyone including the front desk, the new general manager"

Reviewed on May 17, 2025

Wingate by Wyndham - Columbia
Days Inn by Wyndham Rolla
Days Inn by Wyndham Rolla
2.5 out of 5
2006 N Bishop Ave, Rolla, MO
  • 3 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Rolla. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,007 reviews)
"Convenient location just off the highway. Only scramble eggs for breakfast. No other options or pastries."

Reviewed on May 2, 2025

Days Inn by Wyndham Rolla
Osage Village Inn
Osage Village Inn
2.5 out of 5
4616 Osage Beach Parkway, Osage Beach, MO
  • 27 min drive from Lake of the Ozarks
Stay at this hotel in Osage Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7/10 Good! (926 reviews)
Good Place
"Great staff. Great location. Old school with real keys. Room was clean, but lots of stains."

Reviewed on May 8, 2025

Osage Village Inn
Holiday Inn Columbia East by IHG
Holiday Inn Columbia East by IHG
3 out of 5
915 Port Way, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.2/10 Very Good! (975 reviews)
"Everything was wonderful! Convenient, clean, and comfortable!!"

Reviewed on May 11, 2025

Holiday Inn Columbia East by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Central Missouri

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Central Missouri.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Central Missouri’s 4,493 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as . In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Central Missouri hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Central Missouri. No matter your reason for visiting Central Missouri, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Central Missouri hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Central Missouri?

With over 4,493 hotels in Central Missouri, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as .

How to find cheap car rentals in Central Missouri?

Finding a cheap car rental deal in Central Missouri is as easy as scoring cheap hotels in Central Missouri. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.