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Hotels in Central Missouri

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Tonight May 12 - May 13Next weekend May 17 - May 19

Choose from 4424 Central Missouri Hotel Deals

La Quinta Inn & Suites by Wyndham Columbia
La Quinta Inn & Suites by Wyndham Columbia
2.5 out of 5
2500 I 70 Dr Sw, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
The price is $56 per night from May 19 to May 20
$56
per night
May 19 - May 20
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
5.6/10 (1,001 reviews)
"Room was comfortable and clean. Check-in was easy. The breakfast area could have used some attention in terms of cleanliness and being well stocked."

Reviewed on Apr 6, 2024

La Quinta Inn & Suites by Wyndham Columbia
Country Inn & Suites by Radisson, Columbia, MO
Country Inn & Suites by Radisson, Columbia, MO
2.5 out of 5
817 N Keene St, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
The price is $85 per night from May 19 to May 20
$85
per night
May 19 - May 20
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,243 reviews)
"Our initial room had a musty/smokey smell and we requested for a new a room. The receptionist changed our room with no questions asked and we appreciated that very much. The new room was clean and no issues with smell or anything."

Reviewed on May 9, 2024

Country Inn & Suites by Radisson, Columbia, MO
Stoney Creek Hotel Columbia
Stoney Creek Hotel Columbia
2.5 out of 5
2601 S Providence Rd, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
The price is $129 per night from May 13 to May 14
$129
per night
May 13 - May 14
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,154 reviews)
"Great place to stay"

Reviewed on May 7, 2024

Stoney Creek Hotel Columbia
Lodge Of Four Seasons Golf Resort, Marina & Spa
Lodge Of Four Seasons Golf Resort, Marina & Spa
4 out of 5
315 Four Seasons Dr., Lake Ozark, MO
  • 20 min drive from Lake of the Ozarks
The price is $149 per night from May 13 to May 14
$149
per night
May 13 - May 14
Book a stay at this beach resort in Lake Ozark. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the restaurant in our ...
7.4/10 Good! (1,001 reviews)
"Carpet in hallway needs to be repaired (stretched). Outdated a tad, but clean. Staff....can't say enough about them! Fantastic!"

Reviewed on May 6, 2024

Lodge Of Four Seasons Golf Resort, Marina & Spa
Margaritaville Lake Resort Lake of the Ozarks
Margaritaville Lake Resort Lake of the Ozarks
3 out of 5
494 Tan Tar A Drive, Osage Beach, MO
  • 14 min drive from Lake of the Ozarks
The price is $156 per night from May 13 to May 14
$156
per night
May 13 - May 14
Book a stay at this spa resort in Osage Beach. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the restaurant and the helpful staff in ...
8.2/10 Very Good! (1,005 reviews)
"👍"

Reviewed on May 10, 2024

Margaritaville Lake Resort Lake of the Ozarks
Drury Plaza Hotel Columbia East
Drury Plaza Hotel Columbia East
3 out of 5
3100 Interstate 70 Dr. SE, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
The price is $108 per night from May 26 to May 27
$108
per night
May 26 - May 27
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,005 reviews)
Happy camper
"Was very happy with our stay,room was clean and quiet,the meals were good,I would not hesitate to come again"

Reviewed on May 10, 2024

Drury Plaza Hotel Columbia East
Days Inn by Wyndham Rolla
Days Inn by Wyndham Rolla
2.5 out of 5
2006 N Bishop Ave, Rolla, MO
  • 3 hours drive from Lake of the Ozarks
The price is $79 per night from May 13 to May 14
$79
per night
May 13 - May 14
Book a stay at this business-friendly hotel in Rolla. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,000 reviews)
"Very clean Hotel. They were doing work updating the upper level."

Reviewed on Apr 29, 2024

Days Inn by Wyndham Rolla
Best Western Plus Columbia Inn
Best Western Plus Columbia Inn
2.5 out of 5
2904 Clark Lane, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
The price is $85 per night from May 19 to May 20
$85
per night
May 19 - May 20
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,002 reviews)
Modern and clean
"Clean and modern facility. A little pricey for a 1-night stay. No pets allowed, so I likely won't be back anyway. The modern and nicely decorated facilities were a welcome change. The staff was not particularly helpful or outgoing, although I did not have any major issue. Breakfast was better than ..."

Reviewed on May 9, 2024

Best Western Plus Columbia Inn
Ramada by Wyndham Columbia
Ramada by Wyndham Columbia
2.5 out of 5
901 Conley Rd, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
The price is $64 per night from May 13 to May 14
$64
per night
May 13 - May 14
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,004 reviews)
"Friendly staff"

Reviewed on May 9, 2024

Ramada by Wyndham Columbia
Wingate by Wyndham - Columbia
Wingate by Wyndham - Columbia
3 out of 5
3101 Wingate Ct, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
The price is $87 per night from May 19 to May 20
$87
per night
May 19 - May 20
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,010 reviews)
"Check in was quick and efficient. Young man did a great job"

Reviewed on May 9, 2024

Wingate by Wyndham - Columbia
Quality Inn & Suites Columbia I-70
Quality Inn & Suites Columbia I-70
2.5 out of 5
801 Keene St, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
The price is $68 per night from Jun 6 to Jun 7
$68
per night
Jun 6 - Jun 7
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (282 reviews)
"Nice"

Reviewed on May 6, 2024

Quality Inn & Suites Columbia I-70
Osage Village Inn
Osage Village Inn
2.5 out of 5
4616 Osage Beach Parkway, Osage Beach, MO
  • 27 min drive from Lake of the Ozarks
The price is $79 per night from May 13 to May 14
$79
per night
May 13 - May 14
Stay at this hotel in Osage Beach. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (626 reviews)
Great stay and good price
"It was an easy check-in and room was as requested. Great stay. Will be back again!"

Reviewed on Apr 16, 2024

Osage Village Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Central Missouri

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Central Missouri hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Central Missouri.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Central Missouri’s 4,424 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $56. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Central Missouri hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Central Missouri. No matter your reason for visiting Central Missouri, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Central Missouri hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Central Missouri for as low as $56.

How many hotels are there in Central Missouri?

With over 4,424 hotels in Central Missouri, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $56.

How to find cheap car rentals in Central Missouri?

Finding a cheap car rental deal in Central Missouri is as easy as scoring cheap hotels in Central Missouri. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Central Missouri now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Central Missouri right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.