Search for Cheap Deals onHotels in Central Missouri
Choose from 4654 Central Missouri Hotel Deals

Lodge Of Four Seasons Golf Resort, Marina & Spa
Reviewed on Jul 15, 2025

Baymont by Wyndham Columbia, MO
Reviewed on Jul 18, 2025

Inn at Grand Glaize
Reviewed on Jul 13, 2025

Margaritaville Lake Resort Lake of the Ozarks
Reviewed on Jul 13, 2025

Osage Village Inn
Reviewed on Jul 15, 2025

Wingate by Wyndham - Columbia
Reviewed on Jul 13, 2025

Drury Plaza Hotel Columbia East
Reviewed on Jul 17, 2025

Country Inn & Suites by Radisson, Columbia, MO
Reviewed on Jul 16, 2025

Wyndham Executive Center Columbia
Reviewed on Jul 14, 2025

Days Inn by Wyndham Rolla
Reviewed on Jul 15, 2025

Stoney Creek Hotel Columbia
Reviewed on Jul 15, 2025

Ramada by Wyndham Columbia
Reviewed on Jul 16, 2025
Find cheap hotels in Central Missouri
You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Central Missouri hotel with Hotwire to complete your one-of-a-kind travel checklist.
For you, intrepid voyager, Hotwire has a large selection of the best hotels in Central Missouri.
Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Central Missouri’s 4,654 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $72. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Central Missouri hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Central Missouri. No matter your reason for visiting Central Missouri, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About Central Missouri hotels
Where can I find the best last-minute travel deals?
If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Central Missouri for as low as $72.
How many hotels are there in Central Missouri?
With over 4,654 hotels in Central Missouri, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $72.
How to find cheap car rentals in Central Missouri?
Finding a cheap car rental deal in Central Missouri is as easy as scoring cheap hotels in Central Missouri. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.
Top Booked Hotels in Central Missouri
- Lodge Of Four Seasons Golf Resort, Marina & Spa
- Baymont by Wyndham Columbia, MO
- Inn at Grand Glaize
- Margaritaville Lake Resort Lake of the Ozarks
- Wingate by Wyndham - Columbia
- Country Inn & Suites by Radisson, Columbia, MO
- Wyndham Executive Center Columbia
- Stoney Creek Hotel Columbia
- Ramada by Wyndham Columbia
- Baymont by Wyndham Osage Beach
- Days Inn by Wyndham Osage Beach Lake of the Ozarks
- Baymont by Wyndham Rolla
- Hotel Brand
- Hotel Class
- Near An Airport
- Areas Of Central Missouri
- Near An Attraction
- Hotel Theme
- Other Cities Near Central Missouri
- Hotels near University of Missouri
- Hotels near Fort Leonard Wood
- Hotels near Ha Ha Tonka State Park
- Hotels near Bagnell Dam
- Hotels near Mizzou Arena
- Hotels near Lake of the Ozarks and Bagnell Dam Viewpoint
- Hotels near Faurot Field at Memorial Stadium
- Hotels near Missouri University of Science and Technology
- Hotels near Missouri State Fairgrounds
- Hotels near Ozarks Amphitheater
- Hotels near University of Central Missouri
- Hotels near Osage Beach Premium Outlets
- Hotels near The Oaks Golf Club at Tan Tar A Resort
- Hotels near Uranus Fudge Factory And General Store
- Hotels near Montauk State Park
- Hotels near Truman Lake
- Hotels near Columbia Mall
- Hotels near Missouri State Capitol
- Hotels near Missouri State Penitentiary Museum
- Hotels near Women's and Children's Hospital
- Family Hotels in Central Missouri
- Hotels with Free Parking in Central Missouri
- Hotels with a Pool in Central Missouri
- Pet-friendly Hotels in Central Missouri
- Apartment Hotel in Central Missouri
- Hotels with an Indoor Pool in Central Missouri
- Hotels with Hot Tubs in Central Missouri
- Resorts & Hotels with Spas in Central Missouri
- Romantic Hotels in Central Missouri
- Luxury Hotels in Central Missouri
- Hotel Wedding Venues in Central Missouri
- Historic Hotels in Central Missouri
- Beach Hotels in Central Missouri
- Hotels with smoking rooms in Central Missouri
- Casinos in Central Missouri
- Winery Hotels in Central Missouri
- Adults Only Resorts & Hotels in Central Missouri
- Hotels with Free Airport Shuttle in Central Missouri
- Hotels with a Lazy River in Central Missouri
- Waterpark Hotels in Central Missouri
- Osage Beach Hotels
- Lake Ozark Hotels
- Columbia Hotels
- Overland Park Hotels
- Camdenton Hotels
- Sunrise Beach Hotels
- Independence Hotels
- Hermann Hotels
- Olathe Hotels
- Hannibal Hotels
- Lee's Summit Hotels
- Rolla Hotels
- Jefferson City Hotels
- Blue Springs Hotels
- Eminence Hotels
- St. Robert Hotels
- Sedalia Hotels
- Boonville Hotels
- Ozarks Hotels
- Van Buren Hotels