Search for Cheap Deals on
Hotels in Central Missouri

Check Last Minute Central Missouri Hotel Deals

Tonight Jul 19 - Jul 20Next weekend Jul 25 - Jul 27

Choose from 4654 Central Missouri Hotel Deals

Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa

4 out of 5
315 Four Seasons Dr., Lake Ozark, MO
  • 20 min drive from Lake of the Ozarks
Stay at this 4-star beach resort in Lake Ozark. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in ...
7.2/10 Good! (1,001 reviews)
"The staff was very friendly and helpful. The pools are great. There is the main lodge and the Bay Breeze. I would equate staying in the Bay Breeze to staying at Motel 6. There wasn't really a price difference between the two buildings, was a matter of availability. Very run down and stained. AC had ..."

Reviewed on Jul 15, 2025

Lodge Of Four Seasons Golf Resort, Marina & Spa
Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

2.5 out of 5
2500 I 70 Dr Sw, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
8/10 Very Good! (362 reviews)
"Great breakfast Great. Cofdee. Ice. Tge beds. Sleep. Great. Very Confortable. Well. Lighted. Parking. Very. Nice. My. Rating. Is. 5. Stars. !!! Thank you"

Reviewed on Jul 18, 2025

Baymont by Wyndham Columbia, MO
Inn at Grand Glaize

Inn at Grand Glaize

2 out of 5
5142 Osage Beach Pkwy, Osage Beach, MO
  • 24 min drive from Lake of the Ozarks
Book a stay at this golf hotel in Osage Beach. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in ...
7.2/10 Good! (156 reviews)
Enjoyable
"Great stay, great view, and such nice people working there. The doorman was always smiles and happy. Pool was great and tiki bar guy was accommodating. Our king lake view room was big enough for our family with the addition of our blow up matress. Just a great stay."

Reviewed on Jul 13, 2025

Inn at Grand Glaize
Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks

3 out of 5
494 Tan Tar A Drive, Osage Beach, MO
  • 14 min drive from Lake of the Ozarks
Stay at this 3-star spa resort in Osage Beach. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,001 reviews)
"Needs more sidewalks around the property but otherwise we had a fantastic weekend"

Reviewed on Jul 13, 2025

Margaritaville Lake Resort Lake of the Ozarks
Osage Village Inn

Osage Village Inn

2.5 out of 5
4616 Osage Beach Parkway, Osage Beach, MO
  • 27 min drive from Lake of the Ozarks
Stay at this hotel in Osage Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.8/10 (1,003 reviews)
"Always stay here"

Reviewed on Jul 15, 2025

Osage Village Inn
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

3 out of 5
3101 Wingate Ct, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,123 reviews)
"Clean, helpful staff"

Reviewed on Jul 13, 2025

Wingate by Wyndham - Columbia
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

3 out of 5
3100 Interstate 70 Dr. SE, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,200 reviews)
"Wonderful"

Reviewed on Jul 17, 2025

Drury Plaza Hotel Columbia East
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

2.5 out of 5
817 N Keene St, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,516 reviews)
"It was very nice."

Reviewed on Jul 16, 2025

Country Inn & Suites by Radisson, Columbia, MO
Wyndham Executive Center Columbia

Wyndham Executive Center Columbia

3.5 out of 5
2200 I-70 Drive SW, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Stay at this 3.5-star business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,003 reviews)
"I needed a room for the night for my parents, post hospital procedure. I jumped on line and found this room. I went to check them in and the staff jumped through hoops to make their stay a much better option than any I had experienced in many years of hotel stays."

Reviewed on Jul 14, 2025

Wyndham Executive Center Columbia
Days Inn by Wyndham Rolla

Days Inn by Wyndham Rolla

2.5 out of 5
2006 N Bishop Ave, Rolla, MO
  • 3 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Rolla. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,011 reviews)
"Kids loved the pool"

Reviewed on Jul 15, 2025

Days Inn by Wyndham Rolla
Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

2.5 out of 5
2601 S Providence Rd, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.6/10 Excellent! (1,278 reviews)
"We had a great stay. There was a convention happening the day we stayed. We noticed all the employees were very nice and professional. Great job all!"

Reviewed on Jul 15, 2025

Stoney Creek Hotel Columbia
Ramada by Wyndham Columbia

Ramada by Wyndham Columbia

2.5 out of 5
901 Conley Rd, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,003 reviews)
"Great breakfast!"

Reviewed on Jul 16, 2025

Ramada by Wyndham Columbia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Central Missouri

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Central Missouri hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Central Missouri.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Central Missouri’s 4,654 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $72. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Central Missouri hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Central Missouri. No matter your reason for visiting Central Missouri, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Central Missouri hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Central Missouri for as low as $72.

How many hotels are there in Central Missouri?

With over 4,654 hotels in Central Missouri, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $72.

How to find cheap car rentals in Central Missouri?

Finding a cheap car rental deal in Central Missouri is as easy as scoring cheap hotels in Central Missouri. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.