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Featured Central Missouri Resorts & Hotels with Spas

Lodge Of Four Seasons Golf Resort, Marina & Spa
315 Four Seasons Dr., Lake Ozark, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star beach resort in Lake Ozark. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in ...

The Lodge at Old Kinderhook Golf Resort
678 Old Kinderhook Drive, Camdenton, MO
Fully refundable
Stay at this 3-star beach hotel in Camdenton. Enjoy an outdoor pool, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property ...

Hotel Bothwell Sedalia Central District, Ascend Hotel Collection
103 E 4th St, Sedalia, MO
Fully refundable
Stay at this 3-star business-friendly hotel in Sedalia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...

Parkfield Inn
506 Kansas Ave, Clinton, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Clinton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Camden on the Lake Resort & Spa
2359 Bittersweet Road, Lake Ozark, MO
Stay at this 4-star spa resort in Lake Ozark. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular ...

Wingate by Wyndham - Columbia
3101 Wingate Ct, Columbia, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Stoney Creek Hotel Columbia
2601 S Providence Rd, Columbia, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...

Holiday Inn Express Hotel & Suites Rolla - U of Missouri S&T by IHG
1610 Old Wire Outer Rd, Rolla, MO
Fully refundable
Book a stay at this business-friendly hotel in Rolla. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

Parkfield Inn
151 N Dam Access Road, Warsaw, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly motel in Warsaw. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...

Country Inn & Suites by Radisson, Columbia, MO
817 N Keene St, Columbia, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Americas Best Value Inn St. Robert
110 Carmel Valley Way, St. Robert, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Robert. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

Margaritaville Lake Resort Lake of the Ozarks
494 Tan Tar A Drive, Osage Beach, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star spa resort in Osage Beach. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the clean rooms in ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Central Missouri
- Family Hotels in Central Missouri
- Hotels with Free Parking in Central Missouri
- Hotels with a Pool in Central Missouri
- Pet-friendly Hotels in Central Missouri
- Apartment Hotel in Central Missouri
- Hotels with an Indoor Pool in Central Missouri
- Hotels with Hot Tubs in Central Missouri
- Romantic Hotels in Central Missouri
- Luxury Hotels in Central Missouri
- Hotel Wedding Venues in Central Missouri
Top Points of Interests in Central Missouri
- Hotels near University of Missouri
- Hotels near Fort Leonard Wood
- Hotels near Ha Ha Tonka State Park
- Hotels near Bagnell Dam
- Hotels near Ozarks Amphitheater
- Hotels near Lake of the Ozarks and Bagnell Dam Viewpoint
- Hotels near Mizzou Arena
- Hotels near Missouri University of Science and Technology
- Hotels near University of Central Missouri
- Hotels near The Oaks Golf Club at Tan Tar A Resort
- Hotels near Uranus Fudge Factory And General Store
- Hotels near Faurot Field at Memorial Stadium
- Hotels near Columbia Mall
- Hotels near Missouri State Capitol
- Hotels near Warm Springs Ranch
- Hotels near Montauk State Park
- Hotels near Missouri State Penitentiary Museum
- Hotels near Osage Beach Premium Outlets
- Hotels near Truman Lake
- Hotels near Missouri State Fairgrounds
Cities near Central Missouri
- Columbia Hotels (42.4 mi)
- Osage Beach Hotels (18.18 mi)
- Overland Park Hotels (115.02 mi)
- Lake Ozark Hotels (15.36 mi)
- Camdenton Hotels (27.3 mi)
- Sunrise Beach Hotels (16.58 mi)
- Independence Hotels (105.28 mi)
- Hermann Hotels (69.97 mi)
- Olathe Hotels (120.42 mi)
- Jefferson City Hotels (29.65 mi)
- Lee's Summit Hotels (98.68 mi)
- Rolla Hotels (57.94 mi)
- Hannibal Hotels (112.98 mi)
- Boonville Hotels (40 mi)
- St. Robert Hotels (47.76 mi)
- Blue Springs Hotels (96.45 mi)
- Sedalia Hotels (36.63 mi)
- Ozarks Hotels (86.75 mi)
- Fort Leonard Wood Hotels (53.99 mi)
- Eminence Hotels (112.21 mi)
Car Rentals Near Central Missouri
- Car rentals in Columbia
- Car rentals in Osage Beach
- Car rentals in Overland Park
- Car rentals in Lake Ozark
- Car rentals in Camdenton
- Car rentals in Sunrise Beach
- Car rentals in Independence
- Car rentals in Hermann
- Car rentals in Olathe
- Car rentals in Jefferson City
- Car rentals in Lee's Summit
- Car rentals in Rolla
- Car rentals in Hannibal
- Car rentals in Boonville
- Car rentals in St. Robert
- Car rentals in Blue Springs
Top Spa Resort Destinations
- Annapolis Spa Hotels
- Ottawa Valley Spa Hotels
- Tallahassee Spa Hotels
- Appalachian Mountains Spa Hotels
- Corpus Christi Spa Hotels
- Raleigh Spa Hotels
- Syracuse Spa Hotels
- Chattanooga Spa Hotels
- Grand Canyon Spa Hotels
- Toledo Spa Hotels
- Edmonton Spa Hotels
- El Paso Spa Hotels
- Omaha Spa Hotels
- Cincinnati Spa Hotels
- Fargo Spa Hotels
- Des Moines Spa Hotels
- Dayton Spa Hotels
- Flagstaff Spa Hotels
- Little Rock Spa Hotels
- Waco Spa Hotels
Top Booked Hotels in Central Missouri
- Baymont by Wyndham Columbia, MO
- Country Inn & Suites by Radisson, Columbia, MO
- Stoney Creek Hotel Columbia
- Capitol Plaza Hotel Jefferson City
- Lodge Of Four Seasons Golf Resort, Marina & Spa
- Margaritaville Lake Resort Lake of the Ozarks
- Wingate by Wyndham - Columbia
- Wyndham Executive Center Columbia
- Ramada by Wyndham Columbia
- Best Western Plus Columbia Inn
- Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG