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Choose from 170 Hannibal Hotel Deals

Best Western On The River
Best Western On The River
2.5 out of 5
401 North 3rd Street, Hannibal, MO
  • 7 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,000 reviews)
"It was good"

Reviewed on May 26, 2025

Best Western On The River
Quality Inn & Suites Hannibal
Quality Inn & Suites Hannibal
2.5 out of 5
120 Lindsey Drive, Hannibal, MO
  • 10 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,005 reviews)
"Very comfortable, great breakfast and rooms were very comfortable."

Reviewed on May 29, 2025

Quality Inn & Suites Hannibal
Comfort Inn & Suites - Hannibal
Comfort Inn & Suites - Hannibal
2.5 out of 5
4000 Market St, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Book a stay at this spa hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.4/10 Good! (588 reviews)
"Staff is very friendly and property is well taken care of"

Reviewed on May 30, 2025

Comfort Inn & Suites - Hannibal
Sleep Inn & Suites
Sleep Inn & Suites
2.5 out of 5
105 Lakeside Dr, Hannibal, MO
  • 11 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,001 reviews)
"Nice stay, just a little loud."

Reviewed on May 28, 2025

Sleep Inn & Suites
Baymont by Wyndham Hannibal
Baymont by Wyndham Hannibal
2.5 out of 5
4141 Market St, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6/10 (636 reviews)
"was fine"

Reviewed on May 26, 2025

Baymont by Wyndham Hannibal
Motel 6 Hannibal, MO
Motel 6 Hannibal, MO
2 out of 5
123 Huckleberry Heights Dr, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Stay at this motel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,002 reviews)
Oldie but good
"Older hotel but very clean and beds were comfortable. I don’t like to spend a lot of money to stay somewhere when you’re just going to shower and sleep in that room. This fit the bill. Staff were pleasant would stay here again."

Reviewed on May 28, 2025

Motel 6 Hannibal, MO
Super 8 by Wyndham Hannibal
Super 8 by Wyndham Hannibal
2 out of 5
120 Huckleberry Heights Dr, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Stay at this motel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.2/10 Good! (1,000 reviews)
"Nice and quiet after a long day of driving"

Reviewed on May 28, 2025

Super 8 by Wyndham Hannibal
Days Inn by Wyndham Hannibal
Days Inn by Wyndham Hannibal
2 out of 5
4070 Market St, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Stay at this hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions West ...
7.4/10 Good! (151 reviews)
"Very nice. Clean and very friendly lady at the front desk. Nice experience."

Reviewed on May 24, 2025

Days Inn by Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal
2 out of 5
4141B MARKET ST, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Stay at this hotel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7/10 Good! (118 reviews)
"It was a very pleasurable stay at the hotel. Everyone was so nice and kind. The owners of the hotel was extremely friendly and helpful."

Reviewed on May 27, 2025

Howard Johnson BY Wyndham Hannibal
Lighthouse Inn & Suites
Lighthouse Inn & Suites
4 out of 5
612 Mark Twain Ave, Hannibal, MO
  • 7 min drive from Mark Twain Cave
Stay at this 4-star aparthotel in Hannibal. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Molly Brown Museum and Home and Mark Twain ...
"It was a very nice room."

Reviewed on Jan 17, 2025

Lighthouse Inn & Suites
Riverside Inn Hannibal
Riverside Inn Hannibal
2.5 out of 5
111 Bird St, Hannibal, MO
  • 7 min drive from Mark Twain Cave
Stay at this guesthouse in Hannibal. Enjoy free WiFi, free parking, and Netflix. Popular attractions Planters Barn Theater and Mark Twain Boyhood Home and Museum ...
9.2/10 Wonderful! (115 reviews)
"This was a fantastic spot for walking to the local amenities. The room was very comfortable and clean."

Reviewed on May 20, 2025

Riverside Inn Hannibal
Garden House Bed and Breakfast
Garden House Bed and Breakfast
2 out of 5
301 N 5th St, Hannibal, MO
  • 7 min drive from Mark Twain Cave
Stay at this B&B in Hannibal. Enjoy free parking, breakfast (surcharge), and bathrobes. Popular attractions Big River Train Town and Jim's Journey: The Huck ...
8.4/10 Very Good! (17 reviews)
Amazing
"Amazing. Chris was a wonderful host. Breakfast was great."

Reviewed on Apr 5, 2025

Garden House Bed and Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Hannibal

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Frequently Asked Questions About Hannibal hotels

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How many hotels are there in Hannibal?

With over 170 hotels in Hannibal, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $68.

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