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Hotels in Hannibal

Choose from 172 Hannibal Hotel Deals

Best Western On The River

Best Western On The River

2.5 out of 5
401 North 3rd Street Hannibal MO
  • 7 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,005 reviews)
Room was clean. Hotel was in excellent repair. Pool area was well used but well maintained. Staff was super friendly and helpful. The breakfast could be better but it’s a simple buffet and was adequate for being included.

Reviewed on Mar 13, 2026

Best Western On The River
Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

2.5 out of 5
120 Lindsey Drive Hannibal MO
  • 10 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,006 reviews)
Fine

Reviewed on Mar 15, 2026

Quality Inn & Suites Hannibal West
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

2.5 out of 5
105 Lakeside Dr Hannibal MO
  • 10 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,004 reviews)
Would highly recommend to anyone needed an excellent hotel

Reviewed on Mar 16, 2026

Sleep Inn & Suites Hannibal West
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

2.5 out of 5
4000 Market St Hannibal MO
  • 6 min drive from Mark Twain Cave
Book a stay at this spa hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.6/10 Good! (679 reviews)
The front desk woman was so helpful and kind. The location was extremely clean, the breakfast was honestly one of the best I have had for a free continental breakfast, and I loved the hot tub. I felt very safe. Beds were comfortable. Great location.

Reviewed on Mar 15, 2026

Comfort Inn & Suites - Hannibal
Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal

2.5 out of 5
4141 Market St Hannibal MO
  • 6 min drive from Mark Twain Cave
Book a stay at this family-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6.2/10 (745 reviews)
Bed bugs!! I chose this location due to the middle price range for the area and proximity to caves. I checked in with my son and the front desk stated my room and how to get there when a male stranger was behind me. The number is on the card sleeve and should be private for protection. The facilities ...

Reviewed on Mar 15, 2026

Baymont by Wyndham Hannibal
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

2 out of 5
123 Huckleberry Heights Dr Hannibal MO
  • 6 min drive from Mark Twain Cave
Stay at this motel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,002 reviews)
very clean, good

Reviewed on Mar 16, 2026

Motel 6 Hannibal, MO
Lighthouse Inn & Suites

Lighthouse Inn & Suites

4 out of 5
612 Mark Twain Ave Hannibal MO
  • 7 min drive from Mark Twain Cave
Stay at this aparthotel in Hannibal. Enjoy free WiFi, free parking, and dry cleaning or laundry services. Popular attractions Molly Brown Museum and Home and ...
8.8/10 Excellent! (25 reviews)
Nice room. Matched the pictures. Exactly what we were looking for.

Reviewed on Jan 18, 2026

Lighthouse Inn & Suites
Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal

2 out of 5
120 Huckleberry Heights Dr Hannibal MO
  • 6 min drive from Mark Twain Cave
Stay at this motel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.2/10 Good! (1,000 reviews)
Decent breakfast. Hotel is dated, but clean. Great value.

Reviewed on Mar 9, 2026

Super 8 by Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

2 out of 5
4141B MARKET ST Hannibal MO
  • 6 min drive from Mark Twain Cave
Stay at this hotel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (156 reviews)
Smoke detector hanging from ceiling. Dog poop all iver the rocks outside the room. People smoking and load right outside the room.

Reviewed on Mar 7, 2026

Howard Johnson BY Wyndham Hannibal
Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal

2 out of 5
4070 Market St Hannibal MO
  • 6 min drive from Mark Twain Cave
Stay at this hotel in Hannibal. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
7.4/10 Good! (226 reviews)
Clean room. Comfortable bed. The staff were friendly. Convenient on/off location.

Reviewed on Mar 15, 2026

Days Inn by Wyndham Hannibal
Riverside Inn Hannibal

Riverside Inn Hannibal

2.5 out of 5
111 Bird St Hannibal MO
  • 7 min drive from Mark Twain Cave
Stay at this guesthouse in Hannibal. Enjoy free WiFi, free parking, and Netflix. Popular attractions Planters Barn Theater and Mark Twain Boyhood Home and Museum ...
9.4/10 Exceptional! (169 reviews)
Na

Reviewed on Mar 15, 2026

Riverside Inn Hannibal
Holiday Inn Express & Suites Hannibal - Medical Center by IHG

Holiday Inn Express & Suites Hannibal - Medical Center by IHG

2.5 out of 5
120 Shinn Lane Hannibal MO
  • 10 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Holiday Inn Express & Suites Hannibal - Medical Center by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Hannibal

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How many hotels are there in Hannibal?

With over 172 hotels in Hannibal, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $63.

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