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Hotels in Hannibal

Choose from 171 Hannibal Hotel Deals

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

2.5 out of 5
120 Lindsey Drive Hannibal MO
  • 5 min drive from Mark Twain Boyhood Home and Museum
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,009 reviews)
Clean and comfortable. Nice hot breakfast. Great staff, very friendly and welcoming.

Reviewed on Jan 15, 2026

Quality Inn & Suites Hannibal West
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

2.5 out of 5
105 Lakeside Dr Hannibal MO
  • 6 min drive from Mark Twain Boyhood Home and Museum
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,002 reviews)
Beds were comfortable. Breakfast was good

Reviewed on Jan 25, 2026

Sleep Inn & Suites Hannibal West
Best Western On The River

Best Western On The River

2.5 out of 5
401 North 3rd Street Hannibal MO
  • 1 min walk from Mark Twain Boyhood Home and Museum
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,000 reviews)
We had an issue with our Expedia reservation. Tony was professional & provided excellent customer service fixing the issue.

Reviewed on Feb 2, 2026

Best Western On The River
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

2 out of 5
123 Huckleberry Heights Dr Hannibal MO
  • 24 min walk from Mark Twain Boyhood Home and Museum
Stay at this motel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,000 reviews)
The room was spotless and fresh. Assistance was cheerfully offered when needed.

Reviewed on Jan 25, 2026

Motel 6 Hannibal, MO
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

2.5 out of 5
4000 Market St Hannibal MO
  • 5 min drive from Mark Twain Boyhood Home and Museum
Book a stay at this spa hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.6/10 Good! (672 reviews)
Awesome

Reviewed on Jan 26, 2026

Comfort Inn & Suites - Hannibal
Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal

2.5 out of 5
4141 Market St Hannibal MO
  • 6 min drive from Mark Twain Boyhood Home and Museum
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.2/10 (737 reviews)
Very nice and helpful staff. Decent room and breakfast. Building overall is a bit dated.

Reviewed on Dec 15, 2025

Baymont by Wyndham Hannibal
Lighthouse Inn & Suites

Lighthouse Inn & Suites

4 out of 5
612 Mark Twain Ave Hannibal MO
  • 5 min walk from Mark Twain Boyhood Home and Museum
Stay at this aparthotel in Hannibal. Enjoy free WiFi, free parking, and dry cleaning or laundry services. Popular attractions Molly Brown Museum and Home and ...
8.8/10 Excellent! (25 reviews)
Nice room. Matched the pictures. Exactly what we were looking for.

Reviewed on Jan 18, 2026

Lighthouse Inn & Suites
Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

2 out of 5
4141B MARKET ST Hannibal MO
  • 6 min drive from Mark Twain Boyhood Home and Museum
Stay at this hotel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (153 reviews)
Great staff! Very friendly!

Reviewed on Dec 24, 2025

Howard Johnson BY Wyndham Hannibal
Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal

2 out of 5
120 Huckleberry Heights Dr Hannibal MO
  • 24 min walk from Mark Twain Boyhood Home and Museum
Stay at this motel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.2/10 Good! (1,000 reviews)
clean room - soft beds - friendly staff - very welcoming - lobby nice

Reviewed on Jan 2, 2026

Super 8 by Wyndham Hannibal
Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal

2 out of 5
4070 Market St Hannibal MO
  • 6 min drive from Mark Twain Boyhood Home and Museum
Stay at this hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions West ...
7.2/10 Good! (221 reviews)
Thimbs up.

Reviewed on Jan 4, 2026

Days Inn by Wyndham Hannibal
Garth Woodside Mansion B&B

Garth Woodside Mansion B&B

4 out of 5
11069 New London Gravel Rd Hannibal MO
  • 8 min drive from Mark Twain Boyhood Home and Museum
Stay at this B&B in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Bear Creek Park and West Ely Park are located nearby.
9.6/10 Exceptional! (21 reviews)
Garth Mansion is Perfect
The Mansion is spectacular, our room was perfect and the on suite bathroom/shower, fireplace bed, everything was and is fantastic. The staff and the other guests were so friendly they felt like family.

Reviewed on Oct 17, 2025

Garth Woodside Mansion B&B
Riverside Inn Hannibal

Riverside Inn Hannibal

2.5 out of 5
111 Bird St Hannibal MO
  • 2 min walk from Mark Twain Boyhood Home and Museum
Stay at this guesthouse in Hannibal. Enjoy free WiFi, free parking, and Netflix. Popular attractions Planters Barn Theater and Mark Twain Boyhood Home and Museum ...
9.4/10 Exceptional! (166 reviews)
Everything was great. Stayed there several times. Will go again.

Reviewed on Dec 1, 2025

Riverside Inn Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Hannibal

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Frequently Asked Questions About Hannibal hotels

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How many hotels are there in Hannibal?

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