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Best Western On The River

Best Western On The River

2.5 out of 5
401 North 3rd Street, Hannibal, MO
  • 7 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,022 reviews)
"Limited choices for breakfast especially for diabetics or those who have to limit carb intake. No fresh fruit. Check in staff was excellent! Very friendly and informative. Explained the boil water and gave us solutions. Checkout staff not as friendly, seemed distracted with her phone. Everything ..."

Reviewed on Oct 16, 2025

Best Western On The River
Quality Inn & Suites Hannibal

Quality Inn & Suites Hannibal

2.5 out of 5
120 Lindsey Drive, Hannibal, MO
  • 10 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,011 reviews)
"Its a ok place."

Reviewed on Oct 15, 2025

Quality Inn & Suites Hannibal
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

2 out of 5
123 Huckleberry Heights Dr, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Stay at this motel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,007 reviews)
"It was a great place to stay the night while traveling. I really like the hard floor upgrade."

Reviewed on Oct 11, 2025

Motel 6 Hannibal, MO
Sleep Inn & Suites

Sleep Inn & Suites

2.5 out of 5
105 Lakeside Dr, Hannibal, MO
  • 11 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,000 reviews)
"I passed this on to the Front Desk Manager this morning…the room was clean and well-appointed, the beds were terrific, the breakfast was first-rate. Check-in was easy and smooth. The one minor complaint I had was that the TV service did not include access to Public Broadcasting stations. Overall, ..."

Reviewed on Oct 13, 2025

Sleep Inn & Suites
Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal

2.5 out of 5
4141 Market St, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.2/10 (711 reviews)
"Good"

Reviewed on Oct 12, 2025

Baymont by Wyndham Hannibal
Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal

2 out of 5
4070 Market St, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Stay at this hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions West ...
7.2/10 Good! (206 reviews)
"Staff was great."

Reviewed on Sep 16, 2025

Days Inn by Wyndham Hannibal
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

2.5 out of 5
4000 Market St, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Book a stay at this spa hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.6/10 Good! (641 reviews)
"Our room smelled like it had been a smoking room previously. Also the spa was nice but made a loud noise with the jets on."

Reviewed on Sep 30, 2025

Comfort Inn & Suites - Hannibal
Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal

2 out of 5
120 Huckleberry Heights Dr, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Stay at this motel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7/10 Good! (1,000 reviews)
"Wonderful staff"

Reviewed on Sep 28, 2025

Super 8 by Wyndham Hannibal
Lighthouse Inn & Suites

Lighthouse Inn & Suites

4 out of 5
612 Mark Twain Ave, Hannibal, MO
  • 7 min drive from Mark Twain Cave
Stay at this 4-star aparthotel in Hannibal. Enjoy free WiFi, free parking, and dry cleaning or laundry services. Popular attractions Molly Brown Museum and Home ...
8.8/10 Excellent! (21 reviews)
"Very nice room, close enough to walk to riverfront attractions."

Reviewed on Sep 21, 2025

Lighthouse Inn & Suites
Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

2 out of 5
4141B MARKET ST, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Stay at this hotel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7/10 Good! (138 reviews)
"Wonderful and friendly staff, an actual hot real breakfast selection! Clean pool and gaming area, would stay again!"

Reviewed on Sep 1, 2025

Howard Johnson BY Wyndham Hannibal
Riverside Inn Hannibal

Riverside Inn Hannibal

2.5 out of 5
111 Bird St, Hannibal, MO
  • 7 min drive from Mark Twain Cave
Stay at this guesthouse in Hannibal. Enjoy free WiFi, free parking, and Netflix. Popular attractions Planters Barn Theater and Mark Twain Boyhood Home and Museum ...
9.4/10 Exceptional! (156 reviews)
"This was a fun place to stay, history, great food ground floor, great view and comfy beds. Seriously added a fun day to our trip!"

Reviewed on Oct 14, 2025

Riverside Inn Hannibal
Garden House Bed and Breakfast

Garden House Bed and Breakfast

2 out of 5
301 N 5th St, Hannibal, MO
  • 7 min drive from Mark Twain Cave
Stay at this B&B in Hannibal. Enjoy free parking, breakfast (surcharge), and bathrobes. Popular attractions Big River Train Town and Jim's Journey: The Huck ...
8.6/10 Excellent! (28 reviews)
Great B&B
"Host was helpful with local suggestions for things to and places to eat, as well as local history etc. Room was clean and comfortable, breakfast delicious and social. Gret spit close to downtown"

Reviewed on Oct 13, 2025

Garden House Bed and Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Hannibal

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How many hotels are there in Hannibal?

With over 167 hotels in Hannibal, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $62.

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