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Tonight Apr 28 - Apr 29Next weekend May 3 - May 5

Choose from 131 Hannibal Hotel Deals

Motel 6 Hannibal, MO
Motel 6 Hannibal, MO
2 out of 5
123 Huckleberry Heights Dr, Hannibal, MO
  • 24 min walk from Mark Twain Boyhood Home and Museum
The price is $57 per night from Apr 29 to Apr 30
$57
per night
Apr 29 - Apr 30
Stay at this motel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7/10 Good! (1,001 reviews)
"Good all around."

Reviewed on Apr 14, 2024

Motel 6 Hannibal, MO
Best Western On The River
Best Western On The River
2.5 out of 5
401 North 3rd Street, Hannibal, MO
  • 1 min walk from Mark Twain Boyhood Home and Museum
The price is $117 per night from May 2 to May 3
$117
per night
May 2 - May 3
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,004 reviews)
"Nice hotel for a fair price."

Reviewed on Apr 24, 2024

Best Western On The River
Comfort Inn & Suites - Hannibal
Comfort Inn & Suites - Hannibal
2.5 out of 5
4000 Market St, Hannibal, MO
  • 5 min drive from Mark Twain Boyhood Home and Museum
The price is $100 per night from Apr 30 to May 1
$100
per night
Apr 30 - May 1
Stay at this spa hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (464 reviews)
"Quiet nice stay"

Reviewed on Apr 24, 2024

Comfort Inn & Suites - Hannibal
Quality Inn & Suites Hannibal
Quality Inn & Suites Hannibal
2.5 out of 5
120 Lindsey Drive, Hannibal, MO
  • 6 min drive from Mark Twain Boyhood Home and Museum
The price is $106 per night from Apr 29 to Apr 30
$106
per night
Apr 29 - Apr 30
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
7.8/10 Good! (1,002 reviews)
"Room was ok bathroom floor tile had scratches in it. Breakfast was very good. It was close to a restaurant and affordable."

Reviewed on Apr 23, 2024

Quality Inn & Suites Hannibal
Sleep Inn & Suites
Sleep Inn & Suites
2.5 out of 5
105 Lakeside Dr, Hannibal, MO
  • 6 min drive from Mark Twain Boyhood Home and Museum
The price is $116 per night from Apr 29 to Apr 30
$116
per night
Apr 29 - Apr 30
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (922 reviews)
"This place was good, clean room and convenient to downtown Hannibal. I would stay again."

Reviewed on Apr 25, 2024

Sleep Inn & Suites
Baymont by Wyndham Hannibal
Baymont by Wyndham Hannibal
2.5 out of 5
4141 Market St, Hannibal, MO
  • 6 min drive from Mark Twain Boyhood Home and Museum
The price is $67 per night from May 5 to May 6
$67
per night
May 5 - May 6
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
5.8/10 (513 reviews)
"I liked that I was able two get two rooms that were nice without having to pay $1,000. I only had to pay $100 something for two rooms. The only thing I didn't like was the bathroom flooring as I feel it doesn't go with the room. But that's it."

Reviewed on Apr 22, 2024

Baymont by Wyndham Hannibal
Super 8 by Wyndham Hannibal
Super 8 by Wyndham Hannibal
2 out of 5
120 Huckleberry Heights Dr, Hannibal, MO
  • 24 min walk from Mark Twain Boyhood Home and Museum
The price is $67 per night from May 5 to May 6
$67
per night
May 5 - May 6
Stay at this motel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7/10 Good! (1,001 reviews)
"Kind and friendly check in."

Reviewed on Apr 26, 2024

Super 8 by Wyndham Hannibal
Days Inn by Wyndham Hannibal
Days Inn by Wyndham Hannibal
2 out of 5
4070 Market St, Hannibal, MO
  • 6 min drive from Mark Twain Boyhood Home and Museum
The price is $64 per night from May 7 to May 8
$64
per night
May 7 - May 8
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Sodalis Nature Preserve and Rockcliffe ...
7/10 Good! (61 reviews)
"Overnight desk agent was very pleasant and competent. (Dave?)"

Reviewed on Apr 8, 2024

Days Inn by Wyndham Hannibal
Holiday Inn Express And Suites Hannibal - Medical Center, an IHG Hotel
Holiday Inn Express And Suites Hannibal - Medical Center, an IHG Hotel
2.5 out of 5
120 Shinn Lane, Hannibal, MO
  • 6 min drive from Mark Twain Boyhood Home and Museum
The price is $189 per night from May 2 to May 3
$189
per night
May 2 - May 3
Stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.6/10 Exceptional! (383 reviews)
Very clean and friendly staff
"Very friendly staff. Very clean in all areas (even the stairwells). Breakfast was served on glass plates with stainless steel flatware. Lots of variety for breakfast. One of the nicest Holiday Inn Express properties I have stayed in."

Reviewed on Apr 25, 2024

Holiday Inn Express And Suites Hannibal - Medical Center, an IHG Hotel
Howard Johnson BY Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal
2.5 out of 5
4141B MARKET ST, Hannibal, MO
  • 6 min drive from Mark Twain Boyhood Home and Museum
The price is $59 per night from May 12 to May 13
$59
per night
May 12 - May 13
Stay at this hotel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.8/10 (71 reviews)
A good value
"The price is great, it's clean and the staff were friendly and competent. This is a really old hotel, it was actually fun spotting details about how this building has changed over time. It was probably a pretty nice place in the 70's, the pool actually looks pretty nice though we didn't have time ..."

Reviewed on Apr 14, 2024

Howard Johnson BY Wyndham Hannibal
Lighthouse Hospitality Hannibal
Lighthouse Hospitality Hannibal
2.5 out of 5
111 Bird St, Hannibal, MO
  • 2 min walk from Mark Twain Boyhood Home and Museum
The price is $200 per night from Apr 29 to Apr 30
$200
per night
Apr 29 - Apr 30
Stay at this guesthouse in Hannibal. Enjoy free WiFi, free parking, and Netflix. Popular attractions Planters Barn Theater and Mark Twain Boyhood Home and Museum ...
9.2/10 Wonderful! (88 reviews)
Hot Tub Baby
"It was awesome. Very pleasantly surprised at the excellent Decor, and that Tub was excellent. Great little place in a great town."

Reviewed on Jan 8, 2024

Lighthouse Hospitality Hannibal
507 Bridge OLD RIVER ROAD
507 Bridge OLD RIVER ROAD
3 out of 5
507 Bridge St, Hannibal, MO
  • 2 min walk from Mark Twain Boyhood Home and Museum
Stay at this 3-star business-friendly apartment in Hannibal. Enjoy free WiFi, free parking, and private yards. Popular attractions Mark Twain Memorial Lighthouse ...
10/10 Exceptional! (2 reviews)
great spot to stay!
"nice place and clean, great food within walking distance."

Reviewed on Oct 30, 2023

507 Bridge OLD RIVER ROAD
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Hannibal

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Hannibal.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Hannibal’s 131 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $57. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Hannibal hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Hannibal. No matter your reason for visiting Hannibal, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Hannibal hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Hannibal for as low as $57.

How many hotels are there in Hannibal?

With over 131 hotels in Hannibal, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $57.

How to find cheap car rentals in Hannibal?

Finding a cheap car rental deal in Hannibal is as easy as scoring cheap hotels in Hannibal. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Hannibal now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Hannibal right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.