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Hotels in Hannibal

Choose from 178 Hannibal Hotel Deals

Baymont by Wyndham Hannibal
Baymont by Wyndham Hannibal
2.5 out of 5
4141 Market St, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.2/10 (663 reviews)
TV reception
"The stay was very nice. The only problem we had was the reception on the TV. Majority of the channels were extremely fuzzy & couldn’t watch them, so we couldn’t hardly find anything to watch on TV due to this issue."

Reviewed on Jul 6, 2025

Baymont by Wyndham Hannibal
Best Western On The River
Best Western On The River
2.5 out of 5
401 North 3rd Street, Hannibal, MO
  • 7 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,003 reviews)
"Convenient to tourist attractions"

Reviewed on Jul 7, 2025

Best Western On The River
Quality Inn & Suites Hannibal
Quality Inn & Suites Hannibal
2.5 out of 5
120 Lindsey Drive, Hannibal, MO
  • 10 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,003 reviews)
"Floors need deep cleaning. Feet black from floors in rooms"

Reviewed on Jul 6, 2025

Quality Inn & Suites Hannibal
Sleep Inn & Suites
Sleep Inn & Suites
2.5 out of 5
105 Lakeside Dr, Hannibal, MO
  • 11 min drive from Mark Twain Cave
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,001 reviews)
"Clean, easy access from highway yet little to no traffic noise. Excellent hot breakfast"

Reviewed on Jul 6, 2025

Sleep Inn & Suites
Comfort Inn & Suites - Hannibal
Comfort Inn & Suites - Hannibal
2.5 out of 5
4000 Market St, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Book a stay at this spa hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.4/10 Good! (605 reviews)
"Nice stagg"

Reviewed on Jul 10, 2025

Comfort Inn & Suites - Hannibal
Motel 6 Hannibal, MO
Motel 6 Hannibal, MO
2 out of 5
123 Huckleberry Heights Dr, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Stay at this motel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,002 reviews)
"Good queit clean comfortable"

Reviewed on Jul 1, 2025

Motel 6 Hannibal, MO
Super 8 by Wyndham Hannibal
Super 8 by Wyndham Hannibal
2 out of 5
120 Huckleberry Heights Dr, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Stay at this motel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.2/10 Good! (1,005 reviews)
Safe, adequate, cheap
"It seemed to be family owned and we had good customer service. The kids loved the pool. It was an inexpensive stay, but if all you need is a place to crash for a few hours, this was a really reasonable option."

Reviewed on Jul 5, 2025

Super 8 by Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal
2 out of 5
4141B MARKET ST, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Stay at this hotel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7/10 Good! (122 reviews)
"Older hotel that is being refurbished. Decent rooms, quiet and just what we needed for a quick overnight stay while on a 13 hour road trip. Nice breakfast."

Reviewed on Jun 3, 2025

Howard Johnson BY Wyndham Hannibal
Days Inn by Wyndham Hannibal
Days Inn by Wyndham Hannibal
2 out of 5
4070 Market St, Hannibal, MO
  • 6 min drive from Mark Twain Cave
Stay at this hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions West ...
7.2/10 Good! (166 reviews)
"Easy fast and comfortable. Staff was awesome"

Reviewed on Jul 8, 2025

Days Inn by Wyndham Hannibal
Lighthouse Inn & Suites
Lighthouse Inn & Suites
4 out of 5
612 Mark Twain Ave, Hannibal, MO
  • 7 min drive from Mark Twain Cave
Stay at this 4-star aparthotel in Hannibal. Enjoy free WiFi, free parking, and dry cleaning or laundry services. Popular attractions Molly Brown Museum and Home ...
9/10 Wonderful! (11 reviews)
"Location is excellent! Close to historic downtown but far enough away to be quiet and peaceful! Very clean and decor is wonderful!"

Reviewed on Jul 6, 2025

Lighthouse Inn & Suites
Riverside Inn Hannibal
Riverside Inn Hannibal
2.5 out of 5
111 Bird St, Hannibal, MO
  • 7 min drive from Mark Twain Cave
Stay at this guesthouse in Hannibal. Enjoy free WiFi, free parking, and Netflix. Popular attractions Planters Barn Theater and Mark Twain Boyhood Home and Museum ...
9.2/10 Wonderful! (123 reviews)
"The place was clean and nicely updated. We felt safe and it was in a great location (walking distance)to all the historical downtown, museums, shopping and restaurants. A great view of the river and watching of boats! Id have given it 5 stars except for the CONS. Pros: easy walk to alot of attractions, ..."

Reviewed on Jul 8, 2025

Riverside Inn Hannibal
Garden House Bed and Breakfast
Garden House Bed and Breakfast
2 out of 5
301 N 5th St, Hannibal, MO
  • 7 min drive from Mark Twain Cave
Stay at this B&B in Hannibal. Enjoy free parking, breakfast (surcharge), and bathrobes. Popular attractions Big River Train Town and Jim's Journey: The Huck ...
8.4/10 Very Good! (21 reviews)
"We really enjoy the old house experience. The house has been updated yet the original beauty well preserved. We enjoyed the hominess of having the house cat staying outside our room!"

Reviewed on Jun 26, 2025

Garden House Bed and Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Hannibal

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How many hotels are there in Hannibal?

With over 178 hotels in Hannibal, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $63.

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