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Choose from 83 Louisiana Hotel Deals

River's Edge Motel

River's Edge Motel

2 out of 5
201 Mansion St, Louisiana, MO
  • 16 min drive from Mississippi River
Stay at this motel in Louisiana. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews.
8.8/10 Excellent! (348 reviews)
"Room was very clean and fresh smelling. We had stayed before (July 2025) and our room smelled old and damp. This time was MUCH better. Staff was very pleasant. We will use River's Edge again. Thank you so much!"

Reviewed on Oct 13, 2025

River's Edge Motel
The Eagles Nest Inn

The Eagles Nest Inn

3 out of 5
215 Georgia St, Louisiana, MO
  • 17 min drive from Mississippi River
Stay at this 3-star inn in Louisiana. Enjoy free WiFi, free parking, and bathrobes.
9.4/10 Exceptional! (17 reviews)
"Clean. Big bathroom. Bed squeaky. Walkable to river and some eating spots. It is full of history and the building was renovated beautifully. There were no common spaces to sit, it would be nice to have that outside of room 11. We would return."

Reviewed on Oct 12, 2025

The Eagles Nest Inn
Best Western On The River

Best Western On The River

2.5 out of 5
401 North 3rd Street, Hannibal, MO
  • 30 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,016 reviews)
"Staff great room very clean strong smell of chlorine breakfast was OK"

Reviewed on Oct 10, 2025

Best Western On The River
Quality Inn & Suites Hannibal

Quality Inn & Suites Hannibal

2.5 out of 5
120 Lindsey Drive, Hannibal, MO
  • 32 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,004 reviews)
"The breakfast was not good! Biscuits but no gravy or butter. No meat of any kind. Waffles but no butter. Fruit cocktail was expired. Hotel is very nice but. they definitely need to improve their breakfast. Other guests complaining"

Reviewed on Oct 9, 2025

Quality Inn & Suites Hannibal
Sleep Inn & Suites

Sleep Inn & Suites

2.5 out of 5
105 Lakeside Dr, Hannibal, MO
  • 32 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,004 reviews)
"Clean and quick check in"

Reviewed on Oct 10, 2025

Sleep Inn & Suites
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

2 out of 5
123 Huckleberry Heights Dr, Hannibal, MO
  • 29 min drive from Mississippi River
Stay at this motel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,006 reviews)
"It was a great place to stay the night while traveling. I really like the hard floor upgrade."

Reviewed on Oct 11, 2025

Motel 6 Hannibal, MO
Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal

2.5 out of 5
4141 Market St, Hannibal, MO
  • 27 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.2/10 (711 reviews)
"Good"

Reviewed on Oct 12, 2025

Baymont by Wyndham Hannibal
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

2.5 out of 5
4000 Market St, Hannibal, MO
  • 27 min drive from Mississippi River
Book a stay at this spa hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.6/10 Good! (639 reviews)
"Our room smelled like it had been a smoking room previously. Also the spa was nice but made a loud noise with the jets on."

Reviewed on Sep 30, 2025

Comfort Inn & Suites - Hannibal
Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal

2 out of 5
120 Huckleberry Heights Dr, Hannibal, MO
  • 29 min drive from Mississippi River
Stay at this motel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7/10 Good! (1,000 reviews)
"Wonderful staff"

Reviewed on Sep 28, 2025

Super 8 by Wyndham Hannibal
Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal

2 out of 5
4070 Market St, Hannibal, MO
  • 27 min drive from Mississippi River
Stay at this hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions West ...
7.2/10 Good! (206 reviews)
"Staff was great."

Reviewed on Sep 16, 2025

Days Inn by Wyndham Hannibal
Lighthouse Inn & Suites

Lighthouse Inn & Suites

4 out of 5
612 Mark Twain Ave, Hannibal, MO
  • 30 min drive from Mississippi River
Stay at this 4-star aparthotel in Hannibal. Enjoy free WiFi, free parking, and dry cleaning or laundry services. Popular attractions Molly Brown Museum and Home ...
8.8/10 Excellent! (21 reviews)
"Very nice room, close enough to walk to riverfront attractions."

Reviewed on Sep 21, 2025

Lighthouse Inn & Suites
Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

2 out of 5
4141B MARKET ST, Hannibal, MO
  • 27 min drive from Mississippi River
Stay at this hotel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7/10 Good! (138 reviews)
"Wonderful and friendly staff, an actual hot real breakfast selection! Clean pool and gaming area, would stay again!"

Reviewed on Sep 1, 2025

Howard Johnson BY Wyndham Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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