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Hotels in Louisiana

Choose from 78 Louisiana Hotel Deals

River's Edge Motel
River's Edge Motel
2 out of 5
201 Mansion St, Louisiana, MO
  • 16 min drive from Mississippi River
Stay at this motel in Louisiana. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attraction ...
8.8/10 Excellent! (322 reviews)
"Beautiful views of the Mississippi. Proprietor is kind and helpful. Scrupulously clean, this is an older roadside motel with some wear and tear evident. The bathroom was well maintained and the bed was comfortable."

Reviewed on May 28, 2025

River's Edge Motel
The Eagles Nest Inn
The Eagles Nest Inn
3 out of 5
215 Georgia St, Louisiana, MO
  • 17 min drive from Mississippi River
Stay at this 3-star inn in Louisiana. Enjoy free WiFi, free parking, and housekeeping. Popular attraction The Eagle's Nest Winery is located nearby.
"It was very clean and very nice place to stay, has a very home and cozy feeling walking into the room."

Reviewed on Mar 21, 2025

The Eagles Nest Inn
Best Western On The River
Best Western On The River
2.5 out of 5
401 North 3rd Street, Hannibal, MO
  • 30 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,008 reviews)
"It was good"

Reviewed on May 26, 2025

Best Western On The River
Comfort Inn & Suites - Hannibal
Comfort Inn & Suites - Hannibal
2.5 out of 5
4000 Market St, Hannibal, MO
  • 27 min drive from Mississippi River
Book a stay at this spa hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.4/10 Good! (586 reviews)
"Staff very helpful and friendly"

Reviewed on May 23, 2025

Comfort Inn & Suites - Hannibal
Sleep Inn & Suites
Sleep Inn & Suites
2.5 out of 5
105 Lakeside Dr, Hannibal, MO
  • 32 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,007 reviews)
Great!
"Cleanest hotel I ever stayed in! Rooms were quiet and comfortable. Staff was super friendly. Breakfast was great too."

Reviewed on May 26, 2025

Sleep Inn & Suites
Quality Inn & Suites Hannibal
Quality Inn & Suites Hannibal
2.5 out of 5
120 Lindsey Drive, Hannibal, MO
  • 32 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,004 reviews)
"This room had a musty mildew odor but other than that it was fine"

Reviewed on May 24, 2025

Quality Inn & Suites Hannibal
Motel 6 Hannibal, MO
Motel 6 Hannibal, MO
2 out of 5
123 Huckleberry Heights Dr, Hannibal, MO
  • 29 min drive from Mississippi River
Stay at this motel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,000 reviews)
"Just one complaint. They did not leave a light on fo me."

Reviewed on May 20, 2025

Motel 6 Hannibal, MO
Baymont by Wyndham Hannibal
Baymont by Wyndham Hannibal
2.5 out of 5
4141 Market St, Hannibal, MO
  • 27 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6/10 (636 reviews)
"was fine"

Reviewed on May 26, 2025

Baymont by Wyndham Hannibal
Super 8 by Wyndham Hannibal
Super 8 by Wyndham Hannibal
2 out of 5
120 Huckleberry Heights Dr, Hannibal, MO
  • 29 min drive from Mississippi River
Stay at this motel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.2/10 Good! (1,004 reviews)
"Nice and quiet after a long day of driving"

Reviewed on May 28, 2025

Super 8 by Wyndham Hannibal
Days Inn by Wyndham Hannibal
Days Inn by Wyndham Hannibal
2 out of 5
4070 Market St, Hannibal, MO
  • 27 min drive from Mississippi River
Stay at this hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions West ...
7.4/10 Good! (150 reviews)
"Very nice. Clean and very friendly lady at the front desk. Nice experience."

Reviewed on May 24, 2025

Days Inn by Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal
2 out of 5
4141B MARKET ST, Hannibal, MO
  • 27 min drive from Mississippi River
Stay at this hotel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7/10 Good! (116 reviews)
"The owner Al is a great guy. Very helpful and super friendly. Our room was clean and comfortable."

Reviewed on May 22, 2025

Howard Johnson BY Wyndham Hannibal
Riverside Inn Hannibal
Riverside Inn Hannibal
2.5 out of 5
111 Bird St, Hannibal, MO
  • 30 min drive from Mississippi River
Stay at this guesthouse in Hannibal. Enjoy free WiFi, free parking, and Netflix. Popular attractions Planters Barn Theater and Mark Twain Boyhood Home and Museum ...
9.2/10 Wonderful! (115 reviews)
"This was a fantastic spot for walking to the local amenities. The room was very comfortable and clean."

Reviewed on May 20, 2025

Riverside Inn Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Louisiana

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Frequently Asked Questions About Louisiana hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Louisiana?

With over 78 hotels in Louisiana, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $64.

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Finding a cheap car rental deal in Louisiana is as easy as scoring cheap hotels in Louisiana. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.