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Choose from 118 Louisiana Hotel Deals

River's Edge Motel

River's Edge Motel

2 out of 5
201 Mansion St Louisiana MO
  • 16 min drive from Mississippi River
Stay at this motel in Louisiana. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews.
9/10 Wonderful! (366 reviews)
"Upon arrival the property side did not appear very inviting. The area seemed pretty sketchy with a bar on site and some rowdy people outside. As a female, I would not of wanted to stay by myself.However, it was after dark. First impression of the room was dark and dreary. Not updated and very old. ..."

Reviewed on May 31, 2026

River's Edge Motel
The Eagles Nest Inn

The Eagles Nest Inn

3 out of 5
215 Georgia St Louisiana MO
  • 17 min drive from Mississippi River
Stay at this inn in Louisiana. Enjoy free WiFi, free parking, and housekeeping.
9.4/10 Exceptional! (25 reviews)
"vg"

Reviewed on May 31, 2026

The Eagles Nest Inn
Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

2.5 out of 5
120 Lindsey Drive Hannibal MO
  • 32 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,003 reviews)
"Parking was easy and safe, when the staff was available, they were courteous, and breakfast was good."

Reviewed on Jun 4, 2026

Quality Inn & Suites Hannibal West
Best Western On The River

Best Western On The River

2.5 out of 5
401 North 3rd Street Hannibal MO
  • 30 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,002 reviews)
"The room was very clean. The staff was helpful and friendly. The location is very central."

Reviewed on Jun 4, 2026

Best Western On The River
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

2.5 out of 5
4000 Market St Hannibal MO
  • 27 min drive from Mississippi River
Book a stay at this spa hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.6/10 Good! (697 reviews)
"Ok"

Reviewed on Jun 3, 2026

Comfort Inn & Suites - Hannibal
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

2.5 out of 5
105 Lakeside Dr Hannibal MO
  • 32 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,001 reviews)
"The gal at the desk when we checked in was very nice and helpful! The place was clean, comfy beds and quiet. Definitely would stay again"

Reviewed on Jun 1, 2026

Sleep Inn & Suites Hannibal West
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

2 out of 5
123 Huckleberry Heights Dr Hannibal MO
  • 29 min drive from Mississippi River
Stay at this motel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,004 reviews)
"Nice staff, good parking, clean room."

Reviewed on Jun 2, 2026

Motel 6 Hannibal, MO
Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal

2 out of 5
4070 Market St Hannibal MO
  • 27 min drive from Mississippi River
Stay at this hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions West ...
7.4/10 Good! (249 reviews)
"A good place to stay in Hannibal."

Reviewed on May 30, 2026

Days Inn by Wyndham Hannibal
Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal

2.5 out of 5
4141 Market St Hannibal MO
  • 27 min drive from Mississippi River
Book a stay at this family-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6.4/10 (769 reviews)
"The staff were very friendly and helpful, The breakfast was probably the best we had experienced at any hotel where we have stayed. If we pass through the area again, we will likely choose to stay there again."

Reviewed on May 28, 2026

Baymont by Wyndham Hannibal
Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal

2 out of 5
120 Huckleberry Heights Dr Hannibal MO
  • 29 min drive from Mississippi River
Stay at this motel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.2/10 Good! (1,002 reviews)
"Room was clean and for once, with a wall A/C unit in the room, it did not smell super musty/mildew. Hopefully that means they are cleaning the A/C filters regularly. Breakfast was quite nice, but drink options were lacking. Coffee or milk is all I saw. Stayed at the end of May a week after Memorial ..."

Reviewed on Jun 2, 2026

Super 8 by Wyndham Hannibal
Lighthouse Inn & Suites

Lighthouse Inn & Suites

4 out of 5
612 Mark Twain Ave Hannibal MO
  • 30 min drive from Mississippi River
Stay at this aparthotel in Hannibal. Enjoy free WiFi, free parking, and dry cleaning or laundry services. Popular attractions Molly Brown Museum and Home and ...
9/10 Wonderful! (29 reviews)
"Fun themed rooms."

Reviewed on May 31, 2026

Lighthouse Inn & Suites
Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

2 out of 5
4141B MARKET ST Hannibal MO
  • 27 min drive from Mississippi River
Stay at this hotel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (168 reviews)
"The staff was very accommodating to my disability needs. They were cleaning constantly."

Reviewed on May 18, 2026

Howard Johnson BY Wyndham Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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