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Hotels in Louisiana

Choose from 80 Louisiana Hotel Deals

River's Edge Motel

River's Edge Motel

2 out of 5
201 Mansion St Louisiana MO
  • 16 min drive from Mississippi River
Stay at this motel in Louisiana. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews.
8.8/10 Excellent! (358 reviews)
Friendly and efficient check-in. Room was clean and fairly modern.

Reviewed on Dec 25, 2025

River's Edge Motel
The Eagles Nest Inn

The Eagles Nest Inn

3 out of 5
215 Georgia St Louisiana MO
  • 17 min drive from Mississippi River
Stay at this inn in Louisiana. Enjoy free WiFi, free parking, and bathrobes.
9.2/10 Wonderful! (19 reviews)
We are on the road often & Eagles Nest is still our favorite. Been there twice. Will go again.

Reviewed on Nov 22, 2025

The Eagles Nest Inn
Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

2.5 out of 5
120 Lindsey Drive Hannibal MO
  • 32 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,003 reviews)
Nice big clean room

Reviewed on Dec 28, 2025

Quality Inn & Suites Hannibal West
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

2.5 out of 5
105 Lakeside Dr Hannibal MO
  • 32 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,006 reviews)
Jacob was great!

Reviewed on Jan 2, 2026

Sleep Inn & Suites Hannibal West
Lighthouse Inn & Suites

Lighthouse Inn & Suites

4 out of 5
612 Mark Twain Ave Hannibal MO
  • 30 min drive from Mississippi River
Stay at this aparthotel in Hannibal. Enjoy free WiFi, free parking, and dry cleaning or laundry services. Popular attractions Molly Brown Museum and Home and ...
8.6/10 Excellent! (24 reviews)
Average room

Reviewed on Dec 17, 2025

Lighthouse Inn & Suites
Best Western On The River

Best Western On The River

2.5 out of 5
401 North 3rd Street Hannibal MO
  • 30 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,004 reviews)
Breakfast was underwhelming.

Reviewed on Jan 3, 2026

Best Western On The River
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

2 out of 5
123 Huckleberry Heights Dr Hannibal MO
  • 29 min drive from Mississippi River
Stay at this motel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,001 reviews)
Staff was very friendly and courteous. I will go back there in the future.

Reviewed on Dec 25, 2025

Motel 6 Hannibal, MO
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

2.5 out of 5
4000 Market St Hannibal MO
  • 27 min drive from Mississippi River
Book a stay at this spa hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.6/10 Good! (665 reviews)
Clean and comfortable room. Stayed 1 night. Great breakfast options. Friendly and courteous staff. Stayed w dog. Would stay again. Great price.

Reviewed on Jan 2, 2026

Comfort Inn & Suites - Hannibal
Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal

2.5 out of 5
4141 Market St Hannibal MO
  • 27 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.2/10 (735 reviews)
Very nice and helpful staff. Decent room and breakfast. Building overall is a bit dated.

Reviewed on Dec 15, 2025

Baymont by Wyndham Hannibal
Super 8 by Wyndham Bowling Green

Super 8 by Wyndham Bowling Green

2 out of 5
1216 E Champ Clark Dr Bowling Green MO
  • 36 min drive from Mississippi River
Stay at this hotel in Bowling Green. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our ...
8.4/10 Very Good! (486 reviews)
Front desk people,...both evening 25th and morning 26th were very pleasant and helpful.

Reviewed on Dec 28, 2025

Super 8 by Wyndham Bowling Green
Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

2 out of 5
4141B MARKET ST Hannibal MO
  • 27 min drive from Mississippi River
Stay at this hotel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (153 reviews)
Great staff! Very friendly!

Reviewed on Dec 24, 2025

Howard Johnson BY Wyndham Hannibal
Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal

2 out of 5
120 Huckleberry Heights Dr Hannibal MO
  • 29 min drive from Mississippi River
Stay at this motel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.2/10 Good! (1,000 reviews)
My stay was excellent staff very friendly and breakfast was always great

Reviewed on Nov 30, 2025

Super 8 by Wyndham Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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