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Choose from 117 Louisiana Hotel Deals

River's Edge Motel

River's Edge Motel

2 out of 5
201 Mansion St Louisiana MO
  • 16 min drive from Mississippi River
Stay at this motel in Louisiana. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews.
9/10 Wonderful! (363 reviews)
Nice small town. Really stunning view from the hotel parking lot! The staff was friendly, helpful and happy to help.

Reviewed on Apr 6, 2026

River's Edge Motel
The Eagles Nest Inn

The Eagles Nest Inn

3 out of 5
215 Georgia St Louisiana MO
  • 17 min drive from Mississippi River
Stay at this inn in Louisiana. Enjoy free WiFi, free parking, and housekeeping.
9.4/10 Exceptional! (23 reviews)
No front desk, all transactions were done remotely! If there was any issue, it would have to be done over the phone! Thankfully everything was fine, but I not a fan of getting instructions on my phone to check in! What if my phone wasn’t working or not charged since I was on the road! It was a wonderful ...

Reviewed on May 5, 2026

The Eagles Nest Inn
Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

2.5 out of 5
120 Lindsey Drive Hannibal MO
  • 32 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,021 reviews)
Strange odor in the lobby. Breakfast was average. Bathroom could have been cleaner (mirror frame and outside of tub).

Reviewed on May 15, 2026

Quality Inn & Suites Hannibal West
Best Western On The River

Best Western On The River

2.5 out of 5
401 North 3rd Street Hannibal MO
  • 30 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,004 reviews)
Nice, clean. I p

Reviewed on May 15, 2026

Best Western On The River
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

2 out of 5
123 Huckleberry Heights Dr Hannibal MO
  • 29 min drive from Mississippi River
Stay at this motel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,002 reviews)
Parking was easy and secure. Check in was flawless. The room was clean and comfy

Reviewed on May 11, 2026

Motel 6 Hannibal, MO
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

2.5 out of 5
105 Lakeside Dr Hannibal MO
  • 32 min drive from Mississippi River
Book a stay at this business-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,001 reviews)
I am here with my young adult girls and I could not have picked a better place. Tori is an amazing host, and the neighbors are just as nice. They are inviting and welcoming. The street is DARLING. I am in real estate and now want to buy a property here. Tori’s upstairs unit is beautifully designed ...

Reviewed on May 15, 2026

Sleep Inn & Suites Hannibal West
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

2.5 out of 5
4000 Market St Hannibal MO
  • 27 min drive from Mississippi River
Book a stay at this spa hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.6/10 Good! (690 reviews)
Very clean hotel, nothing fancy but everything was very nice. Would recommend.

Reviewed on Apr 28, 2026

Comfort Inn & Suites - Hannibal
Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal

2.5 out of 5
4141 Market St Hannibal MO
  • 27 min drive from Mississippi River
Book a stay at this family-friendly hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6.4/10 (764 reviews)
I just had a 2 night stay & it was good. The room was clean & staff was pleasant. The breakfast was ok, I liked the waffle I made. The pool looks nice but I am not a swimmer anymore so I didn't go in to try it.

Reviewed on May 11, 2026

Baymont by Wyndham Hannibal
Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal

2 out of 5
4070 Market St Hannibal MO
  • 27 min drive from Mississippi River
Stay at this hotel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions West ...
7.4/10 Good! (239 reviews)
Parking was great and the hotel was easy to get to. My only issue is the bed was very uncomfortable and the mattress should be replaced. As it had a very large indent in one side.

Reviewed on May 15, 2026

Days Inn by Wyndham Hannibal
Lighthouse Inn & Suites

Lighthouse Inn & Suites

4 out of 5
612 Mark Twain Ave Hannibal MO
  • 30 min drive from Mississippi River
Stay at this aparthotel in Hannibal. Enjoy free WiFi, free parking, and dry cleaning or laundry services. Popular attractions Molly Brown Museum and Home and ...
9/10 Wonderful! (27 reviews)
AMAZING PLACE! Everything was incredible. Bed was comfortable, tv was large, hot tub big enough for 2, shower was gorgeous, decor was just top notch. This hidden gem needs more attention!

Reviewed on May 3, 2026

Lighthouse Inn & Suites
Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal

2 out of 5
120 Huckleberry Heights Dr Hannibal MO
  • 29 min drive from Mississippi River
Stay at this motel in Hannibal. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.2/10 Good! (1,001 reviews)
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Reviewed on May 11, 2026

Super 8 by Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

2 out of 5
4141B MARKET ST Hannibal MO
  • 27 min drive from Mississippi River
Stay at this hotel in Hannibal. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (166 reviews)
The room was clean . The staff was helpful on things to do in the area. It was a very relaxing and the town was beautiful

Reviewed on May 6, 2026

Howard Johnson BY Wyndham Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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