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Central Missouri

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Central Missouri Flights as Low as $239

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Tue, Sep 15 - Fri, Sep 25
ORD
O'Hare Intl.
COU
Columbia Regional
$239 Roundtrip, found 19 hours ago
$239
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Tue, Sep 15 from O'Hare Intl. to Columbia Regional, returning Fri, Sep 25, priced at $239 found 19 hours ago
United
Fri, Sep 18 - Sun, Sep 20
ORD
O'Hare Intl.
COU
Columbia Regional
$239 Roundtrip, found 1 day ago
$239
Roundtrip
found 1 day ago
Select United flight, departing Fri, Sep 18 from O'Hare Intl. to Columbia Regional, returning Sun, Sep 20, priced at $239 found 1 day ago
United
Tue, Sep 15 - Fri, Sep 25
ORD
O'Hare Intl.
COU
Columbia Regional
$247 Roundtrip, found 19 hours ago
$247
Roundtrip
found 19 hours ago
Select United flight, departing Tue, Sep 15 from O'Hare Intl. to Columbia Regional, returning Fri, Sep 25, priced at $247 found 19 hours ago
American Airlines
Tue, Sep 15 - Fri, Sep 25
ORD
O'Hare Intl.
COU
Columbia Regional
$254 Roundtrip, found 19 hours ago
$254
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Tue, Sep 15 from O'Hare Intl. to Columbia Regional, returning Fri, Sep 25, priced at $254 found 19 hours ago
United
Tue, Sep 15 - Fri, Sep 25
ORD
O'Hare Intl.
COU
Columbia Regional
$256 Roundtrip, found 19 hours ago
$256
Roundtrip
found 19 hours ago
Select United flight, departing Tue, Sep 15 from O'Hare Intl. to Columbia Regional, returning Fri, Sep 25, priced at $256 found 19 hours ago
American Airlines
Fri, Sep 18 - Sun, Sep 20
ORD
O'Hare Intl.
COU
Columbia Regional
$269 Roundtrip, found 1 day ago
$269
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Sep 18 from O'Hare Intl. to Columbia Regional, returning Sun, Sep 20, priced at $269 found 1 day ago
United
Tue, Sep 15 - Fri, Sep 25
ORD
O'Hare Intl.
COU
Columbia Regional
$271 Roundtrip, found 19 hours ago
$271
Roundtrip
found 19 hours ago
Select United flight, departing Tue, Sep 15 from O'Hare Intl. to Columbia Regional, returning Fri, Sep 25, priced at $271 found 19 hours ago
United
Tue, Sep 15 - Fri, Sep 25
ORD
O'Hare Intl.
COU
Columbia Regional
$280 Roundtrip, found 19 hours ago
$280
Roundtrip
found 19 hours ago
Select United flight, departing Tue, Sep 15 from O'Hare Intl. to Columbia Regional, returning Fri, Sep 25, priced at $280 found 19 hours ago
United
Sat, Aug 8 - Wed, Aug 26
PIT
Pittsburgh Intl.
COU
Columbia Regional
$298 Roundtrip, found 19 hours ago
$298
Roundtrip
found 19 hours ago
Select United flight, departing Sat, Aug 8 from Pittsburgh Intl. to Columbia Regional, returning Wed, Aug 26, priced at $298 found 19 hours ago
United
Sat, Aug 8 - Wed, Aug 26
PIT
Pittsburgh Intl.
COU
Columbia Regional
$304 Roundtrip, found 19 hours ago
$304
Roundtrip
found 19 hours ago
Select United flight, departing Sat, Aug 8 from Pittsburgh Intl. to Columbia Regional, returning Wed, Aug 26, priced at $304 found 19 hours ago
American Airlines
Tue, Sep 15 - Fri, Sep 25
ORD
O'Hare Intl.
COU
Columbia Regional
$309 Roundtrip, found 19 hours ago
$309
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Tue, Sep 15 from O'Hare Intl. to Columbia Regional, returning Fri, Sep 25, priced at $309 found 19 hours ago
United
Tue, Sep 15 - Fri, Sep 25
ORD
O'Hare Intl.
COU
Columbia Regional
$317 Roundtrip, found 19 hours ago
$317
Roundtrip
found 19 hours ago
Select United flight, departing Tue, Sep 15 from O'Hare Intl. to Columbia Regional, returning Fri, Sep 25, priced at $317 found 19 hours ago
American Airlines
Tue, Jun 30 - Fri, Jul 3
BNA
Nashville Intl.
COU
Columbia Regional
$376 Roundtrip, found 7 hours ago
$376
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Tue, Jun 30 from Nashville Intl. to Columbia Regional, returning Fri, Jul 3, priced at $376 found 7 hours ago
American Airlines
Fri, Jul 3 - Sat, Jul 25
BUR
Hollywood Burbank
COU
Columbia Regional
$408 Roundtrip, found 4 days ago
$408
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Jul 3 from Hollywood Burbank to Columbia Regional, returning Sat, Jul 25, priced at $408 found 4 days ago
United
Fri, Jul 3 - Tue, Jul 7
TPA
Tampa Intl.
COU
Columbia Regional
$467 Roundtrip, found 8 hours ago
$467
Roundtrip
found 8 hours ago
Select United flight, departing Fri, Jul 3 from Tampa Intl. to Columbia Regional, returning Tue, Jul 7, priced at $467 found 8 hours ago
American Airlines
Fri, Jul 24 - Wed, Jul 29
DFW
Dallas-Fort Worth Intl.
COU
Columbia Regional
$489 Roundtrip, just found
$489
Roundtrip
just found
Select American Airlines flight, departing Fri, Jul 24 from Dallas-Fort Worth Intl. to Columbia Regional, returning Wed, Jul 29, priced at $489 just found

Cheap Flights to Central Missouri

Fall in love at first flight with your vacation to Central Missouri by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Central Missouri on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Central Missouri, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Central Missouri

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Central Missouri with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MKC airport.

What is the cheapest month to fly to Central Missouri?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Central Missouri are in September, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Central Missouri?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Central Missouri.

What airport is best to fly into Central Missouri?

When you’re planning your trip to Central Missouri, convenience is the name of the game. Luckily, Central Missouri Roy Otten Memorial Airfield Airport is nearby so you can deplane and get going on checking off everything on your Central Missouri must-do list.

How much are flights to Central Missouri?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Central Missouri on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $239, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Central Missouri?

The trick to saving a stack of cash on your flight to Central Missouri? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $239 right now, why wait?

Central Missouri Flight Information
Destination airport
Columbia Regional
Destination airport IATA code
COU
Roundtrip price
$238

Last Minute Hotel Deals in Central Missouri

Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa

4 out of 5
315 Four Seasons Dr. Lake Ozark MO
Book a stay at this beach resort in Lake Ozark. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in ...
7.4/10 Good! (1,196 reviews)
"The property is old, and if it were just that, it would be one thing. There was moss growing all over the walkways, a weedy mess all around the buildings. Bugs everywhere. On top if it all, the room was very expensive for the equivalent of a cheap seedy motel room. They charge a resort fee on top ..."

Reviewed on Jun 28, 2026

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Lodge Of Four Seasons Golf Resort, Marina & Spa
Inn at Grand Glaize

Inn at Grand Glaize

2 out of 5
5142 Osage Beach Pkwy Osage Beach MO
Book a stay at this golf hotel in Osage Beach. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in ...
7.4/10 Good! (354 reviews)
"Good location. Staff was great. Very clean. We are going back in July hopefully we can enjoy the pool and other amenities. Can’t wait"

Reviewed on Jun 28, 2026

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Inn at Grand Glaize
Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks

3 out of 5
494 Tan Tar A Drive Osage Beach MO
Book a stay at this spa resort in Osage Beach. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the clean rooms in ...
8.4/10 Very Good! (1,006 reviews)
"All staff was friendly and helpful!"

Reviewed on Jun 26, 2026

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Margaritaville Lake Resort Lake of the Ozarks
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

4 out of 5
3100 Interstate 70 Dr. SE Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,505 reviews)
"Clean and basic room, friendly staff, cool perks at Drury. Very family-friendly."

Reviewed on Jun 28, 2026

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Drury Plaza Hotel Columbia East
Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

2.5 out of 5
2500 I 70 Dr Sw Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
8.2/10 Very Good! (875 reviews)
"The shower curtain did not meet the tub so every shower meant the room flooded. We only had two tiny towels to start with so there was perpetual water on the floor. We did not get any cleaning service so we were out of towels by the second day and could not get help from the front desk. The breakfast ..."

Reviewed on Jun 28, 2026

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Baymont by Wyndham Columbia, MO
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

3 out of 5
3101 Wingate Ct Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,248 reviews)
"Amazing place to stay! I stayed from a long drive from New Mexico and I slept like a baby. Comfortable and big rooms, great beds, tasty breakfast and safe location. Totally recommend it!"

Reviewed on Jun 27, 2026

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Wingate by Wyndham - Columbia
Schmidt's Creek Hotel

Schmidt's Creek Hotel

2 out of 5
5760 Osage Beach Pkwy Osage Beach MO
Book a stay at this golf hotel in Osage Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (551 reviews)
"A good simple no frills room, everything was clean and the value was great! Would stay here again!"

Reviewed on Jun 28, 2026

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Schmidt's Creek Hotel
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

2.5 out of 5
817 N Keene St Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,893 reviews)
"Average property, nothing was poor or broken, some painting needed in some places. Staff did there standard job,nothing above and beyond,expect for housekeeping there was a flower toilet paper sheet. Breakfast was your standard hotel breakfast spread. Pool was clean and the hot tub was working, always ..."

Reviewed on Jun 27, 2026

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Country Inn & Suites by Radisson, Columbia, MO
See all 5,159 properties in Central Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Courtyard by Marriott Columbia Missouri

Courtyard by Marriott Columbia Missouri

3 out of 5
3301 LeMone Industrial Blvd Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Mizzou Arena and Walters-Boone ...
8.6/10 Excellent! (695 reviews)
"We had two mishaps with the hotel. The first is that they had no limo pickup service from the hotel when we arrived at the Columbia airport late at night. It cost us $75 for a taxi ride (10 Miles) to the hotel the first night. Then in the morning, our room was flooded with water from a rain storm ..."

Reviewed on Jun 27, 2026

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Courtyard by Marriott Columbia Missouri
Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

2.5 out of 5
2601 S Providence Rd Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.6/10 Excellent! (1,382 reviews)
"We enjoyed the cottage that we stayed in, it gave us a little bit more feel of being in a log cabin. However, the property is run down and I'm hoping that they're just not putting any more money into it because they see a renovation coming. Our room and the lobby were the only places that were an ..."

Reviewed on Jun 28, 2026

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Stoney Creek Hotel Columbia
The Broadway Columbia - a DoubleTree by Hilton

The Broadway Columbia - a DoubleTree by Hilton

4 out of 5
1111 E Broadway Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (1,004 reviews)
"This was our second stay in a year, here, and we have really enjoyed this hotel. It is extremely close to where we wanted to be in Columbia, and I love that the most. We had breakfast there - food was great. No complaints on the room, other than for the suites, it would be nice to have some paper ..."

Reviewed on Jun 28, 2026

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The Broadway Columbia - a DoubleTree by Hilton
See all 5,159 properties in Central Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.