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Central Missouri

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Central Missouri Flights as Low as $380

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$380 Roundtrip, found 4 hours ago
$380
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $380 found 4 hours ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$386 Roundtrip, found 4 hours ago
$386
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $386 found 4 hours ago
American Airlines
Mon, Jun 30 - Wed, Jul 9
SNA
John Wayne
COU
Columbia Regional
$399 Roundtrip, found 3 days ago
$399
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Jun 30 from John Wayne to Columbia Regional, returning Wed, Jul 9, priced at $399 found 3 days ago
American Airlines
Mon, Jun 30 - Wed, Jul 9
SNA
John Wayne
COU
Columbia Regional
$401 Roundtrip, found 8 hours ago
$401
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Jun 30 from John Wayne to Columbia Regional, returning Wed, Jul 9, priced at $401 found 8 hours ago
American Airlines
Sun, Jun 29 - Wed, Jul 9
SNA
John Wayne
COU
Columbia Regional
$421 Roundtrip, found 3 days ago
$421
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sun, Jun 29 from John Wayne to Columbia Regional, returning Wed, Jul 9, priced at $421 found 3 days ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$426 Roundtrip, found 4 hours ago
$426
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $426 found 4 hours ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$432 Roundtrip, found 4 hours ago
$432
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $432 found 4 hours ago
American Airlines
Sat, Jun 14 - Wed, Jun 18
DTW
Detroit Metropolitan Wayne County
COU
Columbia Regional
$434 Roundtrip, found 13 hours ago
$434
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Sat, Jun 14 from Detroit Metropolitan Wayne County to Columbia Regional, returning Wed, Jun 18, priced at $434 found 13 hours ago
American Airlines
Sat, Jun 14 - Wed, Jun 18
DTW
Detroit Metropolitan Wayne County
COU
Columbia Regional
$440 Roundtrip, found 3 days ago
$440
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Jun 14 from Detroit Metropolitan Wayne County to Columbia Regional, returning Wed, Jun 18, priced at $440 found 3 days ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$450 Roundtrip, found 4 hours ago
$450
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $450 found 4 hours ago
American Airlines
Sat, Jun 14 - Wed, Jun 18
DTW
Detroit Metropolitan Wayne County
COU
Columbia Regional
$453 Roundtrip, found 3 days ago
$453
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Jun 14 from Detroit Metropolitan Wayne County to Columbia Regional, returning Wed, Jun 18, priced at $453 found 3 days ago
United
Tue, Oct 14 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$456 Roundtrip, found 2 days ago
$456
Roundtrip
found 2 days ago
Select United flight, departing Tue, Oct 14 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $456 found 2 days ago
American Airlines
Sat, Jun 7 - Wed, Jun 11
JFK
John F. Kennedy Intl.
COU
Columbia Regional
$478 Roundtrip, found 3 days ago
$478
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Jun 7 from John F. Kennedy Intl. to Columbia Regional, returning Wed, Jun 11, priced at $478 found 3 days ago
American Airlines
Fri, Jun 20 - Thu, Jun 26
PDX
Portland Intl.
COU
Columbia Regional
$576 Roundtrip, found 2 days ago
$576
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Jun 20 from Portland Intl. to Columbia Regional, returning Thu, Jun 26, priced at $576 found 2 days ago
American Airlines
Fri, Jun 6 - Sun, Jun 8
EWR
Newark Liberty Intl. Airport
COU
Columbia Regional
$578 Roundtrip, found 3 days ago
$578
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Jun 6 from Newark Liberty Intl. Airport to Columbia Regional, returning Sun, Jun 8, priced at $578 found 3 days ago
American Airlines
Fri, Jun 6 - Sun, Jun 8
LGA
LaGuardia
COU
Columbia Regional
$578 Roundtrip, found 3 days ago
$578
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Jun 6 from LaGuardia to Columbia Regional, returning Sun, Jun 8, priced at $578 found 3 days ago

Cheap Flights to Central Missouri

Fall in love at first flight with your vacation to Central Missouri by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Central Missouri on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Central Missouri, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Central Missouri

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Central Missouri with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MKC airport.

What is the cheapest month to fly to Central Missouri?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Central Missouri are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Central Missouri?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Central Missouri.

What airport is best to fly into Central Missouri?

When you’re planning your trip to Central Missouri, convenience is the name of the game. Luckily, Central Missouri Roy Otten Memorial Airfield Airport is nearby so you can deplane and get going on checking off everything on your Central Missouri must-do list.

How much are flights to Central Missouri?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Central Missouri on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $380, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Central Missouri?

The trick to saving a stack of cash on your flight to Central Missouri? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $380 right now, why wait?

Central Missouri Flight Information
Destination airport
Columbia Regional
Destination airport IATA code
COU
Roundtrip price
$380

Last Minute Hotel Deals in Central Missouri

Baymont by Wyndham Columbia, MO
Baymont by Wyndham Columbia, MO
2.5 out of 5
2500 I 70 Dr Sw, Columbia, MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.8/10 Good! (257 reviews)
Wash room mess
"The place could use some updates in the bathrooms. The water faucets and tub drains didn't work quite so well."

Reviewed on May 30, 2025

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Baymont by Wyndham Columbia, MO
Margaritaville Lake Resort Lake of the Ozarks
Margaritaville Lake Resort Lake of the Ozarks
3 out of 5
494 Tan Tar A Drive, Osage Beach, MO
Stay at this 3-star spa resort in Osage Beach. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,001 reviews)
"Overall our stay was nice. Disappointed in the hot tub, jets didn't work, had a green color to the water. The pizza place was unable to cook our pizza lunch one of the days, dough came out uncooked. The food places and services offered were all good."

Reviewed on May 26, 2025

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Margaritaville Lake Resort Lake of the Ozarks
Capitol Plaza Hotel Jefferson City
Capitol Plaza Hotel Jefferson City
3.5 out of 5
Jefferson City 415 W. McCarty St, Jefferson City, MO
Book a stay at this business-friendly hotel in Jefferson City. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff ...
6.8/10 (1,000 reviews)
"Friendly staff"

Reviewed on May 26, 2025

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Capitol Plaza Hotel Jefferson City
Country Inn & Suites by Radisson, Columbia, MO
Country Inn & Suites by Radisson, Columbia, MO
2.5 out of 5
817 N Keene St, Columbia, MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,503 reviews)
"Excellent hotel for the price they charged! Will stay here again next time we come to Columbia Missouri."

Reviewed on May 26, 2025

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Country Inn & Suites by Radisson, Columbia, MO
Stoney Creek Hotel Columbia
Stoney Creek Hotel Columbia
2.5 out of 5
2601 S Providence Rd, Columbia, MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.6/10 Excellent! (1,246 reviews)
"Nice place and very reasonably priced. Great rustic charm. Would definitely recommend this place as well as stay there again on future visits to the area."

Reviewed on May 25, 2025

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Stoney Creek Hotel Columbia
Drury Plaza Hotel Columbia East
Drury Plaza Hotel Columbia East
3 out of 5
3100 Interstate 70 Dr. SE, Columbia, MO
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,142 reviews)
"Super nice place to stay."

Reviewed on May 29, 2025

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Drury Plaza Hotel Columbia East
Best Western Plus Columbia Inn
Best Western Plus Columbia Inn
2.5 out of 5
2904 Clark Lane, Columbia, MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,141 reviews)
"Very clean place. The ladies working front desk had awesome personalities. I honestly can say i was very pleased with my stay."

Reviewed on May 30, 2025

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Best Western Plus Columbia Inn
Osage Village Inn
Osage Village Inn
2.5 out of 5
4616 Osage Beach Parkway, Osage Beach, MO
Stay at this hotel in Osage Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7/10 Good! (933 reviews)
"The view"

Reviewed on May 22, 2025

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Osage Village Inn
See all 4,518 properties in Central Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Courtyard by Marriott Columbia Missouri
Courtyard by Marriott Columbia Missouri
3 out of 5
3301 LeMone Industrial Blvd, Columbia, MO
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Lazer Lanes and Walters-Boone ...
8.6/10 Excellent! (600 reviews)
"The staff was awesome. Room clean."

Reviewed on May 25, 2025

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Courtyard by Marriott Columbia Missouri
Stoney Creek Hotel Columbia
Stoney Creek Hotel Columbia
2.5 out of 5
2601 S Providence Rd, Columbia, MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.6/10 Excellent! (1,246 reviews)
"Nice place and very reasonably priced. Great rustic charm. Would definitely recommend this place as well as stay there again on future visits to the area."

Reviewed on May 25, 2025

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Stoney Creek Hotel Columbia
The Broadway Columbia - a DoubleTree by Hilton
The Broadway Columbia - a DoubleTree by Hilton
4 out of 5
1111 E Broadway, Columbia, MO
Stay at this 4-star business-friendly hotel in Columbia. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.2/10 Wonderful! (840 reviews)
"Great"

Reviewed on May 16, 2025

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The Broadway Columbia - a DoubleTree by Hilton
See all 4,518 properties in Central Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.