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Central Missouri

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Central Missouri Flights as Low as $343

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

United
Tue, Oct 20 - Sat, Oct 24
TPA
Tampa Intl.
COU
Columbia Regional
$343 Roundtrip, found 1 day ago
$343
Roundtrip
found 1 day ago
Select United flight, departing Tue, Oct 20 from Tampa Intl. to Columbia Regional, returning Sat, Oct 24, priced at $343 found 1 day ago
American Airlines
Tue, Oct 20 - Sat, Oct 24
TPA
Tampa Intl.
COU
Columbia Regional
$343 Roundtrip, found 1 day ago
$343
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Oct 20 from Tampa Intl. to Columbia Regional, returning Sat, Oct 24, priced at $343 found 1 day ago
United
Tue, Oct 20 - Sat, Oct 24
TPA
Tampa Intl.
COU
Columbia Regional
$348 Roundtrip, found 1 day ago
$348
Roundtrip
found 1 day ago
Select United flight, departing Tue, Oct 20 from Tampa Intl. to Columbia Regional, returning Sat, Oct 24, priced at $348 found 1 day ago
United
Tue, Oct 20 - Sat, Oct 24
TPA
Tampa Intl.
COU
Columbia Regional
$354 Roundtrip, found 1 day ago
$354
Roundtrip
found 1 day ago
Select United flight, departing Tue, Oct 20 from Tampa Intl. to Columbia Regional, returning Sat, Oct 24, priced at $354 found 1 day ago
United
Tue, Oct 20 - Sat, Oct 24
TPA
Tampa Intl.
COU
Columbia Regional
$368 Roundtrip, found 1 day ago
$368
Roundtrip
found 1 day ago
Select United flight, departing Tue, Oct 20 from Tampa Intl. to Columbia Regional, returning Sat, Oct 24, priced at $368 found 1 day ago
United
Tue, Oct 20 - Sat, Oct 24
TPA
Tampa Intl.
COU
Columbia Regional
$373 Roundtrip, found 1 day ago
$373
Roundtrip
found 1 day ago
Select United flight, departing Tue, Oct 20 from Tampa Intl. to Columbia Regional, returning Sat, Oct 24, priced at $373 found 1 day ago
United
Tue, Sep 29 - Sat, Oct 3
EWR
Newark Liberty Intl. Airport
COU
Columbia Regional
$377 Roundtrip, found 2 days ago
$377
Roundtrip
found 2 days ago
Select United flight, departing Tue, Sep 29 from Newark Liberty Intl. Airport to Columbia Regional, returning Sat, Oct 3, priced at $377 found 2 days ago
American Airlines
Sat, Oct 3 - Tue, Oct 6
DAY
James M. Cox Dayton Intl.
COU
Columbia Regional
$383 Roundtrip, found 14 hours ago
$383
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Sat, Oct 3 from James M. Cox Dayton Intl. to Columbia Regional, returning Tue, Oct 6, priced at $383 found 14 hours ago
United
Wed, Sep 30 - Thu, Oct 8
DAY
James M. Cox Dayton Intl.
COU
Columbia Regional
$393 Roundtrip, just found
$393
Roundtrip
just found
Select United flight, departing Wed, Sep 30 from James M. Cox Dayton Intl. to Columbia Regional, returning Thu, Oct 8, priced at $393 just found
United
Sat, Oct 3 - Tue, Oct 6
DAY
James M. Cox Dayton Intl.
COU
Columbia Regional
$399 Roundtrip, found 14 hours ago
$399
Roundtrip
found 14 hours ago
Select United flight, departing Sat, Oct 3 from James M. Cox Dayton Intl. to Columbia Regional, returning Tue, Oct 6, priced at $399 found 14 hours ago
United
Wed, Sep 30 - Thu, Oct 8
DAY
James M. Cox Dayton Intl.
COU
Columbia Regional
$408 Roundtrip, just found
$408
Roundtrip
just found
Select United flight, departing Wed, Sep 30 from James M. Cox Dayton Intl. to Columbia Regional, returning Thu, Oct 8, priced at $408 just found
American Airlines
Tue, Oct 20 - Sat, Oct 24
TPA
Tampa Intl.
COU
Columbia Regional
$414 Roundtrip, found 1 day ago
$414
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Oct 20 from Tampa Intl. to Columbia Regional, returning Sat, Oct 24, priced at $414 found 1 day ago
American Airlines
Sat, Oct 10 - Mon, Oct 12
SAN
San Diego Intl.
COU
Columbia Regional
$424 Roundtrip, found 8 hours ago
$424
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Sat, Oct 10 from San Diego Intl. to Columbia Regional, returning Mon, Oct 12, priced at $424 found 8 hours ago
United
Tue, Oct 20 - Sat, Oct 24
TPA
Tampa Intl.
COU
Columbia Regional
$430 Roundtrip, found 1 day ago
$430
Roundtrip
found 1 day ago
Select United flight, departing Tue, Oct 20 from Tampa Intl. to Columbia Regional, returning Sat, Oct 24, priced at $430 found 1 day ago
United
Tue, Oct 20 - Sat, Oct 24
TPA
Tampa Intl.
COU
Columbia Regional
$435 Roundtrip, found 1 day ago
$435
Roundtrip
found 1 day ago
Select United flight, departing Tue, Oct 20 from Tampa Intl. to Columbia Regional, returning Sat, Oct 24, priced at $435 found 1 day ago
United
Sat, Oct 10 - Mon, Oct 12
CLD
McClellan-Palomar
COU
Columbia Regional
$1,172 Roundtrip, found 8 hours ago
$1,172
Roundtrip
found 8 hours ago
Select United flight, departing Sat, Oct 10 from McClellan-Palomar to Columbia Regional, returning Mon, Oct 12, priced at $1,172 found 8 hours ago

Cheap Flights to Central Missouri

Fall in love at first flight with your vacation to Central Missouri by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Central Missouri on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Central Missouri, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Central Missouri

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Central Missouri with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MKC airport.

What is the cheapest month to fly to Central Missouri?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Central Missouri are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Central Missouri?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Central Missouri.

What airport is best to fly into Central Missouri?

When you’re planning your trip to Central Missouri, convenience is the name of the game. Luckily, Central Missouri Roy Otten Memorial Airfield Airport is nearby so you can deplane and get going on checking off everything on your Central Missouri must-do list.

How much are flights to Central Missouri?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Central Missouri on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $343, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Central Missouri?

The trick to saving a stack of cash on your flight to Central Missouri? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $343 right now, why wait?

Central Missouri Flight Information
Destination airport
Columbia Regional
Destination airport IATA code
COU
Roundtrip price
$343

Last Minute Hotel Deals in Central Missouri

Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

2.5 out of 5
2500 I 70 Dr Sw Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
8.2/10 Very Good! (1,048 reviews)
"Rooms were clean, but had a strong clean ing odor. Breakfast was okay. Staff was friendly."

Reviewed on Sep 27, 2026

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Baymont by Wyndham Columbia, MO
Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks

3 out of 5
494 Tan Tar A Drive Osage Beach MO
Book a stay at this spa resort in Osage Beach. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the clean rooms in ...
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Margaritaville Lake Resort Lake of the Ozarks
Inn at Grand Glaize

Inn at Grand Glaize

2 out of 5
5142 Osage Beach Pkwy Osage Beach MO
Book a stay at this golf hotel in Osage Beach. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in ...
7.4/10 Good! (513 reviews)
"We had an issue with the toilet the evening we checked in. We called the front desk asking for assistance. However, the issue was never taken care of and no one from the hotel even followed up with us. We had to walk downstairs any time we needed to use the restroom. HUGE inconvenience with 4 people ..."

Reviewed on Sep 25, 2026

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Inn at Grand Glaize
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

4 out of 5
3100 Interstate 70 Dr. SE Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
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Drury Plaza Hotel Columbia East
Hotel Blu

Hotel Blu

2.5 out of 5
3402 Interstate 70 Dr SE Columbia MO
Stay at this hotel in Columbia. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Stephens Lake Park and Liddell Dam are located ...
6.6/10 (215 reviews)
"The place can use a deep clean, it's not too bad on the surface but gets pretty gross when you look around the base of the toilet and the corners of the floors. But overall it's not bad. The kiosk check in is a little lame, I feel like you should just pay someone to physically be there vs saving ..."

Reviewed on Sep 26, 2026

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Hotel Blu
Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

2.5 out of 5
2601 S Providence Rd Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.6/10 Excellent! (1,404 reviews)
"We loved the pool! The rooms were clean!"

Reviewed on Sep 27, 2026

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Stoney Creek Hotel Columbia
Best Western Plus Columbia Inn

Best Western Plus Columbia Inn

2.5 out of 5
2904 Clark Lane Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,449 reviews)
"Bed was comfortable, breakfast was good, good location for our visit."

Reviewed on Sep 26, 2026

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Best Western Plus Columbia Inn
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

2.5 out of 5
817 N Keene St Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
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Country Inn & Suites by Radisson, Columbia, MO
See all 5,217 properties in Central Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Courtyard by Marriott Columbia Missouri

Courtyard by Marriott Columbia Missouri

3 out of 5
3301 LeMone Industrial Blvd Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Walters-Boone County Historic ...
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Courtyard by Marriott Columbia Missouri
Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

2.5 out of 5
2601 S Providence Rd Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.6/10 Excellent! (1,404 reviews)
"We loved the pool! The rooms were clean!"

Reviewed on Sep 27, 2026

Get rates
Stoney Creek Hotel Columbia
The Broadway Columbia - a DoubleTree by Hilton

The Broadway Columbia - a DoubleTree by Hilton

4 out of 5
1111 E Broadway Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff in our ...
Get rates
The Broadway Columbia - a DoubleTree by Hilton
See all 5,217 properties in Central Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.