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Central Missouri

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Central Missouri Flights as Low as $380

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$380 Roundtrip, found 2 hours ago
$380
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $380 found 2 hours ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$386 Roundtrip, found 2 hours ago
$386
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $386 found 2 hours ago
American Airlines
Mon, Aug 11 - Thu, Aug 14
MSY
Louis Armstrong New Orleans Intl.
TBN
St. Robert Regional
$395 Roundtrip, found 6 days ago
$395
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Aug 11 from Louis Armstrong New Orleans Intl. to St. Robert Regional, returning Thu, Aug 14, priced at $395 found 6 days ago
American Airlines
Mon, Aug 11 - Thu, Aug 14
MSY
Louis Armstrong New Orleans Intl.
TBN
St. Robert Regional
$412 Roundtrip, found 6 days ago
$412
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Aug 11 from Louis Armstrong New Orleans Intl. to St. Robert Regional, returning Thu, Aug 14, priced at $412 found 6 days ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$413 Roundtrip, found 2 hours ago
$413
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $413 found 2 hours ago
American Airlines
Sat, Oct 11 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$413 Roundtrip, found 1 hour ago
$413
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $413 found 1 hour ago
American Airlines
Sat, Oct 11 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$419 Roundtrip, found 1 hour ago
$419
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $419 found 1 hour ago
American Airlines
Fri, Oct 10 - Sat, Oct 11
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$424 Roundtrip, found 4 days ago
$424
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Oct 10 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Sat, Oct 11, priced at $424 found 4 days ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$426 Roundtrip, found 2 hours ago
$426
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $426 found 2 hours ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$432 Roundtrip, found 2 hours ago
$432
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $432 found 2 hours ago
American Airlines
Fri, Oct 10 - Sat, Oct 11
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$437 Roundtrip, found 4 days ago
$437
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Oct 10 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Sat, Oct 11, priced at $437 found 4 days ago
American Airlines
Mon, Aug 11 - Thu, Aug 14
MSY
Louis Armstrong New Orleans Intl.
TBN
St. Robert Regional
$440 Roundtrip, found 6 days ago
$440
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Aug 11 from Louis Armstrong New Orleans Intl. to St. Robert Regional, returning Thu, Aug 14, priced at $440 found 6 days ago
American Airlines
Fri, Oct 10 - Sat, Oct 11
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$442 Roundtrip, found 4 days ago
$442
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Oct 10 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Sat, Oct 11, priced at $442 found 4 days ago
American Airlines
Sat, Oct 11 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$446 Roundtrip, found 1 hour ago
$446
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $446 found 1 hour ago
American Airlines
Fri, Oct 10 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$446 Roundtrip, found 1 day ago
$446
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Oct 10 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $446 found 1 day ago
United
Mon, Oct 6 - Sat, Oct 18
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$462 Roundtrip, found 2 days ago
$462
Roundtrip
found 2 days ago
Select United flight, departing Mon, Oct 6 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Sat, Oct 18, priced at $462 found 2 days ago

Cheap Flights to Central Missouri

Fall in love at first flight with your vacation to Central Missouri by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Central Missouri on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Central Missouri, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Central Missouri

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Central Missouri with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MKC airport.

What is the cheapest month to fly to Central Missouri?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Central Missouri are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Central Missouri?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Central Missouri.

What airport is best to fly into Central Missouri?

When you’re planning your trip to Central Missouri, convenience is the name of the game. Luckily, Central Missouri Roy Otten Memorial Airfield Airport is nearby so you can deplane and get going on checking off everything on your Central Missouri must-do list.

How much are flights to Central Missouri?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Central Missouri on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $380, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Central Missouri?

The trick to saving a stack of cash on your flight to Central Missouri? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $380 right now, why wait?

Central Missouri Flight Information
Destination airport
Columbia Regional
Destination airport IATA code
COU
Roundtrip price
$380

Last Minute Hotel Deals in Central Missouri

Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa

4 out of 5
315 Four Seasons Dr., Lake Ozark, MO
Stay at this 4-star beach resort in Lake Ozark. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in ...
7.2/10 Good! (1,028 reviews)
"Nice pools and great scenery"

Reviewed on Jul 24, 2025

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Lodge Of Four Seasons Golf Resort, Marina & Spa
Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

2.5 out of 5
2500 I 70 Dr Sw, Columbia, MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
8/10 Very Good! (381 reviews)
"The staff and our room was excellent. Will stay again"

Reviewed on Jul 24, 2025

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Baymont by Wyndham Columbia, MO
Inn at Grand Glaize

Inn at Grand Glaize

2 out of 5
5142 Osage Beach Pkwy, Osage Beach, MO
Book a stay at this golf hotel in Osage Beach. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in ...
7.2/10 Good! (184 reviews)
"Frieny staff, great staff at bar/ restaurant, great front door greeter. Nice view of lake. Nice pool/ poolside bar."

Reviewed on Jul 27, 2025

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Inn at Grand Glaize
Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks

3 out of 5
494 Tan Tar A Drive, Osage Beach, MO
Stay at this 3-star spa resort in Osage Beach. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,018 reviews)
"The chairs at the pool were terrible. Metal bar was very uncomfortable. Pillows in rooms were not good at all. Would rather have two firmer pillows than 6 flat ones"

Reviewed on Jul 26, 2025

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Margaritaville Lake Resort Lake of the Ozarks
Osage Village Inn

Osage Village Inn

2.5 out of 5
4616 Osage Beach Parkway, Osage Beach, MO
Stay at this hotel in Osage Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.8/10 (1,020 reviews)
"Nice affordable place to stay. It does have a smell to the place, don’t know if it use to allow smoking but that’s kinda what it smelled like."

Reviewed on Jul 27, 2025

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Osage Village Inn
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

3 out of 5
3100 Interstate 70 Dr. SE, Columbia, MO
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,212 reviews)
"From the check in until we left, everything was wonderful!!!"

Reviewed on Jul 27, 2025

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Drury Plaza Hotel Columbia East
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

2.5 out of 5
817 N Keene St, Columbia, MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,553 reviews)
"Our room was clean and fresh and the bed was excellent for a good night’s rest. The breakfast area was nice and clean and we had a good a good selection for breakfast."

Reviewed on Jul 24, 2025

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Country Inn & Suites by Radisson, Columbia, MO
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

3 out of 5
3101 Wingate Ct, Columbia, MO
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,124 reviews)
"Great value for the price"

Reviewed on Jul 25, 2025

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Wingate by Wyndham - Columbia
See all 4,648 properties in Central Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Courtyard by Marriott Columbia Missouri

Courtyard by Marriott Columbia Missouri

3 out of 5
3301 LeMone Industrial Blvd, Columbia, MO
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Lazer Lanes and Walters-Boone ...
8.6/10 Excellent! (619 reviews)
"Took 10 minutes to get a beer because staff shortage."

Reviewed on Jul 26, 2025

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Courtyard by Marriott Columbia Missouri
Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

2.5 out of 5
2601 S Providence Rd, Columbia, MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.6/10 Excellent! (1,278 reviews)
"Fantastic hotel"

Reviewed on Jul 25, 2025

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Stoney Creek Hotel Columbia
The Broadway Columbia - a DoubleTree by Hilton

The Broadway Columbia - a DoubleTree by Hilton

4 out of 5
1111 E Broadway, Columbia, MO
Stay at this 4-star business-friendly hotel in Columbia. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.2/10 Wonderful! (864 reviews)
"Very nice hotel. Beds are super comfy."

Reviewed on Jul 22, 2025

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The Broadway Columbia - a DoubleTree by Hilton
See all 4,648 properties in Central Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.