Search Cheap Flights to
Missouri from $166

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Cheap round-trip flights to Missouri

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Frontier Airlines
Frontier Airlines
United
Frontier Airlines
United
Delta
Frontier Airlines
American Airlines
Frontier Airlines
Frontier Airlines
Frontier Airlines
Delta
American Airlines
Spirit Airlines
Alaska Airlines

Flights to Missouri starting at $166

Have you been telling yourself, “2025 is the year I travel more and sit less”? Well, here we are and there you are. So, where are you going? Looks like a flight to Missouri is calling. Good thing we can help you bag that flight out of town for cheap, so you can get your resolutions resolved.

Travel like you mean it

When you land it’s not straight to the tourist traps for you. You have things to do and see in Missouri that aren’t on a map or in the “Best of. . .” guides. You know this region is filled with hidden haunts, locals-only know favorites, and the off-beat-so-weird-it’s-amazing places. And you plan to find every last one of them. Good thing you’ll save a grip of cash on your flight so you can daytrip far and wide.

You won’t have to wing it

So how do you score that killer deal on a flight to Missouri? Easy, go through us. These aren’t pie in the sky deals, but ones you can actually score. Filter flights to Missouri by:

  • Hotwire Hot Rate: Do you have a flexible schedule? Hit up the Hotwire Hot Rate and land a super cheap flight to Missouri. We’ll reveal the airline and exact time after you book.
  • Price: How low can we go? Find out. We have prices from $166 to $583.
  • Duration: Want to get to Missouri as fast as you can? Or maybe you don’t mind taking your time to save a few bucks here and there.
  • Departure or Arrival: Like to arrive in the a.m. to get your day going? Or are you a night owl that knows the best fun happens late night? The choice is yours.

So are you going to live up to those travel plans or kick the can to next year? Book your flight to Missouri today and get going.

Last Minute Hotel Deals in Missouri

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,667 reviews)
"Great hotel, just walkable from Gateway Arch"

Reviewed on May 12, 2025

Hyatt Regency St. Louis at The Arch
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street, St. Louis, MO
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (2,538 reviews)
"Great hotel next to arch"

Reviewed on May 13, 2025

Drury Plaza Hotel St. Louis at the Arch
Thousand Hills Resort Hotel

Thousand Hills Resort Hotel

3 out of 5
120 Wildwood Dr S, Branson, MO
Stay at this 3-star golf hotel in Branson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the restaurant in our reviews. Popular ...
8/10 Very Good! (3,727 reviews)
"Very nice place to stay! Staff was extremely friendly and helpful!"

Reviewed on May 14, 2025

Thousand Hills Resort Hotel
Save an average of 15% on thousands of hotels when you're signed in
Orangewood Inn & Suites Kansas City Airport

Orangewood Inn & Suites Kansas City Airport

3.5 out of 5
11828 NW Plaza Circle, Kansas City, MO
Stay at this 3.5-star hotel in Kansas City. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the pool in our ...
9/10 Wonderful! (2,215 reviews)
"Very nice, clean and comfortable"

Reviewed on May 14, 2025

Orangewood Inn & Suites Kansas City Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.