Search Cheap Flights to
St. Charles

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

St. Charles Flights as Low as $72

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Sat, Feb 28 - Sat, Feb 28
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$72 Roundtrip, found 8 hours ago
$72
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Sat, Feb 28 from Denver Intl. to Lambert-St. Louis Intl., returning Sat, Feb 28, priced at $72 found 8 hours ago
Frontier Airlines
Sat, Feb 7 - Sat, Feb 14
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$78 Roundtrip, found 8 hours ago
$78
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Sat, Feb 7 from Denver Intl. to Lambert-St. Louis Intl., returning Sat, Feb 14, priced at $78 found 8 hours ago
Frontier Airlines
Wed, Feb 11 - Wed, Feb 18
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$100 Roundtrip, found 8 hours ago
$100
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Wed, Feb 11 from Denver Intl. to Lambert-St. Louis Intl., returning Wed, Feb 18, priced at $100 found 8 hours ago
United
Sat, Feb 28 - Wed, Mar 4
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$157 Roundtrip, found 14 hours ago
$157
Roundtrip
found 14 hours ago
Select United flight, departing Sat, Feb 28 from Denver Intl. to Lambert-St. Louis Intl., returning Wed, Mar 4, priced at $157 found 14 hours ago
Frontier Airlines
Mon, Feb 23 - Wed, Feb 25
BDL
Bradley Intl.
STL
Lambert-St. Louis Intl.
$158 Roundtrip, found 1 day ago
$158
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Feb 23 from Bradley Intl. to Lambert-St. Louis Intl., returning Wed, Feb 25, priced at $158 found 1 day ago
Frontier Airlines
Sat, Feb 7 - Sat, Feb 14
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$160 Roundtrip, found 8 hours ago
$160
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Sat, Feb 7 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Sat, Feb 14, priced at $160 found 8 hours ago
Delta
Sat, Feb 28 - Sat, Feb 28
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$171 Roundtrip, found 8 hours ago
$171
Roundtrip
found 8 hours ago
Select Delta flight, departing Sat, Feb 28 from Denver Intl. to Lambert-St. Louis Intl., returning Sat, Feb 28, priced at $171 found 8 hours ago
American Airlines
Wed, Feb 25 - Sat, Feb 28
OMA
Eppley Field
STL
Lambert-St. Louis Intl.
$179 Roundtrip, found 1 day ago
$179
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Feb 25 from Eppley Field to Lambert-St. Louis Intl., returning Sat, Feb 28, priced at $179 found 1 day ago
Frontier Airlines
Wed, Feb 25 - Wed, Mar 11
ONT
Los Angeles - Ontario Intl.
STL
Lambert-St. Louis Intl.
$179 Roundtrip, found 8 hours ago
$179
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Wed, Feb 25 from Los Angeles - Ontario Intl. to Lambert-St. Louis Intl., returning Wed, Mar 11, priced at $179 found 8 hours ago
Frontier Airlines
Tue, Mar 10 - Wed, Mar 11
LAX
Los Angeles Intl.
STL
Lambert-St. Louis Intl.
$213 Roundtrip, found 8 hours ago
$213
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Tue, Mar 10 from Los Angeles Intl. to Lambert-St. Louis Intl., returning Wed, Mar 11, priced at $213 found 8 hours ago
Bargain Flight
Tue, Mar 17 - Wed, Mar 18
DCA
Ronald Reagan Washington National
STL
Lambert-St. Louis Intl.
$231 Roundtrip, found 2 days ago
$231
Roundtrip
found 2 days ago
Select Bargain Flight flight, departing Tue, Mar 17 from Ronald Reagan Washington National to Lambert-St. Louis Intl., returning Wed, Mar 18, priced at $231 found 2 days ago
Frontier Airlines
Thu, Apr 9 - Mon, Apr 13
SJC
Norman Y. Mineta San Jose Intl.
STL
Lambert-St. Louis Intl.
$251 Roundtrip, found 17 hours ago
$251
Roundtrip
found 17 hours ago
Select Frontier Airlines flight, departing Thu, Apr 9 from Norman Y. Mineta San Jose Intl. to Lambert-St. Louis Intl., returning Mon, Apr 13, priced at $251 found 17 hours ago
Delta
Sat, Feb 7 - Sat, Feb 7
DAL
Love Field
STL
Lambert-St. Louis Intl.
$257 Roundtrip, found 6 days ago
$257
Roundtrip
found 6 days ago
Select Delta flight, departing Sat, Feb 7 from Love Field to Lambert-St. Louis Intl., returning Sat, Feb 7, priced at $257 found 6 days ago
Hawaiian Airlines
Mon, Apr 13 - Wed, Apr 15
SJC
Norman Y. Mineta San Jose Intl.
STL
Lambert-St. Louis Intl.
$283 Roundtrip, found 2 days ago
$283
Roundtrip
found 2 days ago
Select Hawaiian Airlines flight, departing Mon, Apr 13 from Norman Y. Mineta San Jose Intl. to Lambert-St. Louis Intl., returning Wed, Apr 15, priced at $283 found 2 days ago
Alaska Airlines
Wed, Feb 25 - Tue, Mar 10
ONT
Los Angeles - Ontario Intl.
STL
Lambert-St. Louis Intl.
$315 Roundtrip, found 8 hours ago
$315
Roundtrip
found 8 hours ago
Select Alaska Airlines flight, departing Wed, Feb 25 from Los Angeles - Ontario Intl. to Lambert-St. Louis Intl., returning Tue, Mar 10, priced at $315 found 8 hours ago
American Airlines
Sun, Jan 25 - Mon, Feb 2
PNS
Pensacola Intl.
STL
Lambert-St. Louis Intl.
$351 Roundtrip, found 14 hours ago
$351
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Sun, Jan 25 from Pensacola Intl. to Lambert-St. Louis Intl., returning Mon, Feb 2, priced at $351 found 14 hours ago

Cheap Flights to St. Charles

Fall in love at first flight with your vacation to St. Charles by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to St. Charles on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in St. Charles, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to St. Charles

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to St. Charles with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to St. Charles?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to St. Charles are in February, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to St. Charles?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to St. Charles.

What airport is best to fly into St. Charles?

When you’re planning your trip to St. Charles, convenience is the name of the game. Luckily, St. Charles Lambert-St. Louis Intl. Airport is nearby so you can deplane and get going on checking off everything on your St. Charles must-do list.

How much are flights to St. Charles?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to St. Charles on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $72, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to St. Charles?

The trick to saving a stack of cash on your flight to St. Charles? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $72 right now, why wait?

St. Charles Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$72

Last Minute Hotel Deals in St. Charles

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
Book a stay at this luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms in our reviews. ...
8.4/10 Very Good! (1,012 reviews)
Very clean

Reviewed on Jan 16, 2026

Get rates
Ameristar Casino Resort and Spa
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 out of 5
1190 S Main St St. Charles MO
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,001 reviews)
Yes

Reviewed on Jan 21, 2026

Get rates
Country Inn & Suites by Radisson, St. Charles Historic District
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

3 out of 5
380 Mulholland Drive St. Charles MO
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,000 reviews)
Nice staff

Reviewed on Jan 19, 2026

Get rates
Drury Plaza Hotel St. Louis St. Charles
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

2.5 out of 5
3720 W Clay St St. Charles MO
Book a stay at this golf hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
8/10 Very Good! (1,000 reviews)
Very comfortable beds, hot breakfast with a good variety.

Reviewed on Jan 18, 2026

Get rates
Hampton Inn St. Charles St. Peters
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

2.5 out of 5
1400 S 5th St St. Charles MO
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,002 reviews)
The staff is amazing! This was our 2nd stay and the staff was great each time. Very clean, updates being made. I will stay here again and recommended to anyone.

Reviewed on Jan 16, 2026

Get rates
Comfort Suites St Charles - St Louis
Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel

3 out of 5
1425 South 5th Street St. Charles MO
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,006 reviews)
The staff was great. The breakfast was what you expect from a $98 a night hotel. They had a workout room. The bed was not very comfortable though. All in all for the price i would stay there again.

Reviewed on Jan 19, 2026

Get rates
Best Western Plus The Charles Hotel
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

3.5 out of 5
2 Convention Center Plz St. Charles MO
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free parking, and room service. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,006 reviews)
One of the two people checking people in was very discriminatory. I was waiting in line and an African American lady came in significantly after me. The employee was African American and checked her in ahead of me. I see this as reverse discrimination as I am Caucasian. If this were reversed it would ...

Reviewed on Jan 18, 2026

Get rates
Embassy Suites by Hilton St. Louis St. Charles
Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area

2.5 out of 5
1410 SOUTH 5TH STREET St. Charles MO
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (643 reviews)
Staff. Each one friendlier than the next. Got a helpful dinner recommendation from desk agent, but also smiles and laughs all around. Breakfast quality was also quite good. Will definitely stay there again if we travel to St. Charles.

Reviewed on Jan 8, 2026

Get rates
Hampton Inn & Suites St. Charles Old Town Area
See all 2,310 properties in St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.