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Hotels in St. Charles

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Tonight Apr 26 - Apr 27Next weekend May 2 - May 4

Choose from 2253 St. Charles Hotel Deals

Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
4.5 out of 5
1 Ameristar Blvd, St. Charles, MO
  • 1 min walk from Ameristar Casino St. Charles
The price is $214 per night from Apr 30 to May 1
$214
includes taxes & fees
Apr 30 - May 1
Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms and the property ...
8.2/10 Very Good! (1,004 reviews)
"Everything was very clean, restaurants were good, and staff was awesome."

Reviewed on Apr 22, 2025

Ameristar Casino Resort and Spa
Drury Plaza Hotel St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles
3 out of 5
380 Mulholland Drive, St. Charles, MO
  • 5 min walk from Ameristar Casino St. Charles
The price is $128 per night from May 4 to May 5
$128
includes taxes & fees
May 4 - May 5
Stay at this 3-star business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,002 reviews)
"Everything was great."

Reviewed on Apr 23, 2025

Drury Plaza Hotel St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles
3.5 out of 5
2 Convention Center Plz, St. Charles, MO
  • 11 min walk from Ameristar Casino St. Charles
The price is $159 per night from May 4 to May 5
$159
includes taxes & fees
May 4 - May 5
Stay at this 3.5-star business-friendly hotel in St. Charles. Enjoy free breakfast, free parking, and a free area shuttle. Our guests praise the breakfast and ...
8.8/10 Excellent! (1,139 reviews)
"Great staff, fantastic hotel."

Reviewed on Apr 25, 2025

Embassy Suites by Hilton St. Louis St. Charles
Baymont by Wyndham St. Charles
Baymont by Wyndham St. Charles
2.5 out of 5
801 Veterans Memorial Parkway, St. Charles, MO
  • 9 min walk from Ameristar Casino St. Charles
Stay at this hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8/10 Very Good! (1,001 reviews)
"Every employee I came across was very friendly. Good experience!"

Reviewed on Apr 20, 2025

Baymont by Wyndham St. Charles
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
4 out of 5
315 Chestnut St, St. Louis, MO
  • 36 min drive from Ameristar Casino St. Charles
The price is $136 per night from May 22 to May 23
$136
includes taxes & fees
May 22 - May 23
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,623 reviews)
"Location was perfect and it was also family and pet friendly! Very clean and organized."

Reviewed on Apr 24, 2025

Hyatt Regency St. Louis at The Arch
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
3 out of 5
2 South 4th Street, St. Louis, MO
  • 36 min drive from Ameristar Casino St. Charles
The price is $140 per night from May 4 to May 5
$140
includes taxes & fees
May 4 - May 5
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (2,472 reviews)
"No complaint's!Rooms were very clean, and all the staff is very friendly and very helpful. I would definitely stay there again."

Reviewed on Apr 25, 2025

Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Airport
2.5 out of 5
10810 Pear Tree Ln, St. Ann, MO
  • 11 min drive from Ameristar Casino St. Charles
The price is $106 per night from May 1 to May 2
$106
includes taxes & fees
May 1 - May 2
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (2,543 reviews)
"Neat and clean Nice service"

Reviewed on Apr 26, 2025

Pear Tree Inn St. Louis Airport
Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
  • 24 min drive from Ameristar Casino St. Charles
The price is $116 per night from May 25 to May 26
$116
includes taxes & fees
May 25 - May 26
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,972 reviews)
"The lobby is very nice. The staff was very informative & friendly. Will definitely book here again."

Reviewed on Apr 24, 2025

Clayton Plaza Hotel & Extended Stay
Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
  • 20 min walk from Ameristar Casino St. Charles
The price is $143 per night from May 1 to May 2
$143
includes taxes & fees
May 1 - May 2
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,871 reviews)
"Liked the slot choices and non smoking area. The room had comfortable beds, pillows, and linens."

Reviewed on Apr 23, 2025

Hollywood Casino & Hotel St. Louis
River City Casino & Hotel
River City Casino & Hotel
4 out of 5
777 River City Casino Blvd, St. Louis, MO
  • 45 min drive from Ameristar Casino St. Charles
The price is $126 per night from May 7 to May 8
$126
includes taxes & fees
May 7 - May 8
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,169 reviews)
"Staff was wonderful and so helpful."

Reviewed on Apr 22, 2025

River City Casino & Hotel
Drury Inn & Suites St. Louis Union Station
Drury Inn & Suites St. Louis Union Station
3 out of 5
201 S 20th St, St. Louis, MO
  • 34 min drive from Ameristar Casino St. Charles
The price is $132 per night from Apr 30 to May 1
$132
includes taxes & fees
Apr 30 - May 1
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,096 reviews)
"We liked the historic location and the friendly staff. Everyone staying there seemed to be in a good mood. It was uplifting to see so many families enjoying themselves. When we return to Saint Louis we plan to stay there again."

Reviewed on Apr 23, 2025

Drury Inn & Suites St. Louis Union Station
21C Museum Hotel St Louis
21C Museum Hotel St Louis
4.5 out of 5
1528 Locust street, St. Louis, MO
  • 34 min drive from Ameristar Casino St. Charles
The price is $193 per night from May 22 to May 23
$193
includes taxes & fees
May 22 - May 23
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,086 reviews)
"I always love staying at this hotel! The decor is beautiful and the drinks and food are top notch!"

Reviewed on Apr 22, 2025

21C Museum Hotel St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in St. Charles

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