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Hotels in St. Charles

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Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
  • 1 min walk from Ameristar Casino St. Charles
Book a stay at this luxury hotel in St. Charles. Enjoy a full-service spa, 6 restaurants, and a casino. Our guests praise the clean rooms in our reviews. Popular ...
8.6/10 Excellent! (1,008 reviews)
Always a nice stay here! Food and shops are convenient.

Reviewed on May 9, 2026

Ameristar Casino Resort and Spa
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

3 out of 5
380 Mulholland Drive St. Charles MO
  • 5 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,007 reviews)
Happy hour was great

Reviewed on May 8, 2026

Drury Plaza Hotel St. Louis St. Charles
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

2.5 out of 5
1400 S 5th St St. Charles MO
  • 5 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,010 reviews)
Beautiful hotel, gorgeous room, huge bathroom, nice couch. Super friendly staff throughout. Parking lot not in great shape, difficult to find the entrance to the parking! Behind another hotel, inside on a frontage road. So convenient and close to restaurants, the Ameristar Casino, movie theater, ...

Reviewed on May 9, 2026

Comfort Suites St Charles - St Louis
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 out of 5
1190 S Main St St. Charles MO
  • 6 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,022 reviews)
We were allowed to check in early and the chocolate chip cookies were a nice lift after cycling 20 miles in the rain. We were allowed to hose down our bikes and given hotel towels to wipe away some of the trail sand.

Reviewed on May 8, 2026

Country Inn & Suites by Radisson, St. Charles Historic District
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

3.5 out of 5
2 Convention Center Plz St. Charles MO
  • 11 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free parking, and room service. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,005 reviews)
Very nice good service and food

Reviewed on Apr 28, 2026

Embassy Suites by Hilton St. Louis St. Charles
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
  • 36 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,063 reviews)
Room was great. Clean and comfortable. We only had 1 face towel in the room and I waited 45 mins prior to check out for toothpaste. Those are minor. This hotel is beautiful and I will be back.

Reviewed on May 9, 2026

Hyatt Regency St. Louis at The Arch
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
  • 38 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,264 reviews)
Clean and tidy place

Reviewed on May 8, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
  • 24 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,199 reviews)
The breakfast was great The staff when we checked in was super friendly, but she did not explain that I had to get a paper form them to be exempt from paying $20 for parking in the car garage-so I had to pay $20 for that. :( The sheet/blanket had a brown spot in the top corner The lamp would not ...

Reviewed on May 9, 2026

Clayton Plaza Hotel & Extended Stay
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
  • 34 min drive from Ameristar Casino St. Charles
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,825 reviews)
Loved the look of the building and where it was located but the one thing I didn't like was there was no stairs. Everyone had to use the elevator.

Reviewed on May 9, 2026

21C Museum Hotel St Louis
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
  • 36 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.6/10 Exceptional! (3,413 reviews)
Wonderful place to stay. Staff is very helpful and friendly. Definately would stay again.

Reviewed on May 8, 2026

Drury Plaza Hotel St. Louis at the Arch
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
  • 13 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (1,081 reviews)
The hotel was clean and looked amazing. Apart from the first employee we talked to, he was great, the others were awful. Waited ages for a drink until another employee walked by. No “how was your stay” or “thanks for staying” or nothing when we checked out. Just a rude “printed receipt or email.” ...

Reviewed on May 8, 2026

Renaissance St. Louis Airport Hotel
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
  • 36 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
9.4/10 Exceptional! (1,181 reviews)
Very clean. Slightly loud but that's just the environment next to stadium but not enough that it caused issues. Loved the hotel and location.

Reviewed on May 7, 2026

Live by Loews - St.Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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