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Choose from 2362 St. Charles Hotel Deals

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
  • 1 min walk from Ameristar Casino St. Charles
Book a stay at this luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms in our reviews. ...
8.4/10 Very Good! (1,005 reviews)
Rooms are spacious.

Reviewed on Mar 20, 2026

Ameristar Casino Resort and Spa
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

2.5 out of 5
1400 S 5th St St. Charles MO
  • 5 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,000 reviews)
Extremely comfortable beds and good shower. Big room. Good breakfast. Only thing I would change is to get a room on the north side of building. On south side, I-70 traffic is noisy.

Reviewed on Mar 18, 2026

Comfort Suites St Charles - St Louis
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 out of 5
1190 S Main St St. Charles MO
  • 6 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,002 reviews)
Clean, comfortable room. Close to main attractions we were interested in visiting.

Reviewed on Mar 17, 2026

Country Inn & Suites by Radisson, St. Charles Historic District
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

3 out of 5
380 Mulholland Drive St. Charles MO
  • 5 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,002 reviews)
Great area, clean accommodations. The option for drinks and dinner nightly along with breakfast each morning is a huge bonus!

Reviewed on Mar 19, 2026

Drury Plaza Hotel St. Louis St. Charles
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

2.5 out of 5
3720 W Clay St St. Charles MO
  • 7 min drive from Ameristar Casino St. Charles
Book a stay at this golf hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
8/10 Very Good! (1,000 reviews)
Everything was great as always at this location as i have stayed here many times

Reviewed on Mar 17, 2026

Hampton Inn St. Charles St. Peters
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

3.5 out of 5
2 Convention Center Plz St. Charles MO
  • 11 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free parking, and room service. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,006 reviews)
2 Pool was closed all night and that's the reason we came with the kids. When we arrived our refrigerator wasn't working and had to wait in the room for it to be swapped out. Last night we had to wait forever for someone to bring out more plates for the apps and same with breakfast

Reviewed on Mar 21, 2026

Embassy Suites by Hilton St. Louis St. Charles
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
  • 36 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (3,354 reviews)
Great location and breakfast

Reviewed on Mar 21, 2026

Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
  • 34 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,877 reviews)
Good breakfast

Reviewed on Mar 21, 2026

Pear Tree Inn St. Louis Near Union Station
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
  • 24 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,124 reviews)
Staff was very nice and responsive but property is extremely run down, old and in need of renovation. No pool on-site, no nearby restaurants and too far from downtown St. Louis

Reviewed on Mar 22, 2026

Clayton Plaza Hotel & Extended Stay
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
  • 34 min drive from Ameristar Casino St. Charles
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,680 reviews)
Traveled with a toddler and met our needs. Had a king room and liked it had a big storage closet so our stuff wasn’t all over the room. Only complaints was the fridge was small and there wasn’t an ice machine. I was able to go down to the desk and they got some from the restaurant but I needed more ...

Reviewed on Mar 21, 2026

21C Museum Hotel St Louis
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
  • 20 min walk from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (2,201 reviews)
Great hotel for the hockey tournament... very nice staff... great location. The air quality was poor nearing the casino and awful inside... otherwise a great stay

Reviewed on Mar 21, 2026

Hollywood Casino & Hotel St. Louis
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
  • 36 min drive from Ameristar Casino St. Charles
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,983 reviews)
Clean room.

Reviewed on Mar 21, 2026

Hyatt Regency St. Louis at The Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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