Search for Cheap Deals on
Hotels in St. Charles

Check Last Minute St. Charles Hotel Deals

Tonight Mar 1 - Mar 2Next weekend Mar 7 - Mar 9

Choose from 2342 St. Charles Hotel Deals

Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
4.5 out of 5
1 Ameristar Blvd, St. Charles, MO
  • 1 min walk from Ameristar Casino St. Charles
The price is $214 per night from Mar 9 to Mar 10
$214
includes taxes & fees
Mar 9 - Mar 10
Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms and the property ...
8.2/10 Very Good! (1,000 reviews)
Vday25
"It was amazing!"

Reviewed on Feb 18, 2025

Ameristar Casino Resort and Spa
Embassy Suites by Hilton St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles
3.5 out of 5
2 Convention Center Plz, St. Charles, MO
  • 11 min walk from Ameristar Casino St. Charles
The price is $146 per night from Mar 30 to Mar 31
$146
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3.5-star business-friendly hotel in St. Charles. Enjoy free breakfast, free parking, and a free area shuttle. Our guests praise the breakfast and ...
8.8/10 Excellent! (1,165 reviews)
"Rooms and pool could use a little upgrade but overall exactly what we needed and breakfast was delicious"

Reviewed on Feb 23, 2025

Embassy Suites by Hilton St. Louis St. Charles
Baymont by Wyndham St. Charles
Baymont by Wyndham St. Charles
2.5 out of 5
801 Veterans Memorial Parkway, St. Charles, MO
  • 9 min walk from Ameristar Casino St. Charles
The price is $83 per night from Mar 10 to Mar 11
$83
includes taxes & fees
Mar 10 - Mar 11
Stay at this hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8/10 Very Good! (1,001 reviews)
Needs some TLC
"Old property, pool was not working; Front desk worker and others were very friendly and pleasant"

Reviewed on Feb 24, 2025

Baymont by Wyndham St. Charles
Drury Plaza Hotel St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles
3 out of 5
380 Mulholland Drive, St. Charles, MO
  • 5 min walk from Ameristar Casino St. Charles
The price is $125 per night from Mar 9 to Mar 10
$125
includes taxes & fees
Mar 9 - Mar 10
Stay at this 3-star business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,000 reviews)
Another great stay!
"Another great Drury stay. Nice and clean."

Reviewed on Feb 24, 2025

Drury Plaza Hotel St. Louis St. Charles
Country Inn & Suites by Radisson, St. Charles Historic District
Country Inn & Suites by Radisson, St. Charles Historic District
2.5 out of 5
1190 S Main St, St. Charles, MO
  • 6 min walk from Ameristar Casino St. Charles
The price is $131 per night from Mar 30 to Mar 31
$131
includes taxes & fees
Mar 30 - Mar 31
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,001 reviews)
"Lovely historical district, recent refurb"

Reviewed on Feb 24, 2025

Country Inn & Suites by Radisson, St. Charles Historic District
Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. Peters
2.5 out of 5
3720 W Clay St, St. Charles, MO
  • 7 min drive from Ameristar Casino St. Charles
The price is $109 per night from Mar 9 to Mar 10
$109
includes taxes & fees
Mar 9 - Mar 10
Book a stay at this golf hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
8/10 Very Good! (1,001 reviews)
"Very friendly staff"

Reviewed on Feb 17, 2025

Hampton Inn St. Charles St. Peters
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
4 out of 5
315 Chestnut St, St. Louis, MO
  • 36 min drive from Ameristar Casino St. Charles
The price is $137 per night from Mar 9 to Mar 10
$137
includes taxes & fees
Mar 9 - Mar 10
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,578 reviews)
"Very beautiful hotel, clean & friendly staff. Check-in was flawless & beds were comfortable."

Reviewed on Feb 24, 2025

Hyatt Regency St. Louis at The Arch
Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
  • 20 min walk from Ameristar Casino St. Charles
The price is $133 per night from Mar 2 to Mar 3
$133
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,818 reviews)
"This hotel has the BEST SUITES"

Reviewed on Feb 26, 2025

Hollywood Casino & Hotel St. Louis
Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
  • 24 min drive from Ameristar Casino St. Charles
The price is $111 per night from Mar 23 to Mar 24
$111
includes taxes & fees
Mar 23 - Mar 24
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,984 reviews)
Great staff. Old musty hotel
"Staff was excellent and very friendly. The hotel is very dated. The mattress and pillows were not comfortable. We requested two additional pillows because the ones provided appeared to be smaller than a standard size, we reserved a king suite, and they told us they had no extra pillows."

Reviewed on Feb 25, 2025

Clayton Plaza Hotel & Extended Stay
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
3 out of 5
2 South 4th Street, St. Louis, MO
  • 36 min drive from Ameristar Casino St. Charles
The price is $158 per night from Mar 9 to Mar 10
$158
includes taxes & fees
Mar 9 - Mar 10
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (2,395 reviews)
"This is an incredible hotel. Location is awesome, quick walk (less than 5 minute walk to anywhere you want to go ). Close to airport, food and front desk and staff are top notch. My wife kept asking me how I found this place. Pay the extra $ and get the room with a view.Worth every dollar"

Reviewed on Feb 27, 2025

Drury Plaza Hotel St. Louis at the Arch
River City Casino & Hotel
River City Casino & Hotel
4 out of 5
777 River City Casino Blvd, St. Louis, MO
  • 45 min drive from Ameristar Casino St. Charles
The price is $133 per night from Mar 2 to Mar 3
$133
includes taxes & fees
Mar 2 - Mar 3
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,102 reviews)
River City Casino/ hotel
"We love everything under one roof.. beds are super comfy amazing shower"

Reviewed on Feb 27, 2025

River City Casino & Hotel
Sonesta ES Suites St. Louis - Chesterfield
Sonesta ES Suites St. Louis - Chesterfield
3 out of 5
15431 Conway Rd, Chesterfield, MO
  • 20 min drive from Ameristar Casino St. Charles
The price is $108 per night from Mar 9 to Mar 10
$108
includes taxes & fees
Mar 9 - Mar 10
Stay at this hotel in Chesterfield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,001 reviews)
Nice but close to the interstate
"The stay was nice. I was VERY close to the interstate so there was a lot of noise from the traffic, but I turned the fan on for the thermostat and it helped. I would stay again."

Reviewed on Feb 25, 2025

Sonesta ES Suites St. Louis - Chesterfield
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in St. Charles

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your St. Charles hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in St. Charles.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of St. Charles’s 2,342 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $83. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great St. Charles hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in St. Charles. No matter your reason for visiting St. Charles, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About St. Charles hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in St. Charles for as low as $83.

How many hotels are there in St. Charles?

With over 2,342 hotels in St. Charles, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $83.

How to find cheap car rentals in St. Charles?

Finding a cheap car rental deal in St. Charles is as easy as scoring cheap hotels in St. Charles. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.