Search for Cheap Deals onSpa Resort Hotels in St. Charles
Check Last Minute St. Charles Hotel Deals
You choose what matters — star rating, location, amenities.
We pick the perfect hotel, packed with all your must-haves.
Your hotel is revealed right after booking, and you save up to 60%!
Featured St. Charles Resorts & Hotels with Spas
Ameristar Casino Resort and Spa
1 Ameristar Blvd, St. Charles, MO
Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 5 restaurants. Our guests praise the clean rooms and the property ...
Research Park Inn St Louis West – Chesterfield
32 Research Park Circle, St. Charles, MO
Stay at this 3-star business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Embassy Suites by Hilton St. Louis St. Charles
2 Convention Center Plz, St. Charles, MO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in St. Charles. Enjoy free breakfast, free parking, and a free area shuttle. Our guests praise the breakfast and ...
Country Inn & Suites by Radisson, St. Charles, MO
1190 S Main St, St. Charles, MO
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Drury Plaza Hotel St. Louis St. Charles
380 Mulholland Drive, St. Charles, MO
Stay at this 3-star business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Hampton Inn St. Charles St. Peters
3720 W Clay St, St. Charles, MO
Fully refundableReserve now, pay when you stay
Book a stay at this golf hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in St. Charles
- Historic Hotels in St. Charles
- Casinos in St. Charles
- Hotels with Free Parking in St. Charles
- Family Hotels in St. Charles
- Hotels with a Pool in St. Charles
- Hotels with an Indoor Pool in St. Charles
- Pet-friendly Hotels in St. Charles
- Hotel Wedding Venues in St. Charles
- Hotels with Hot Tubs in St. Charles
- Romantic Hotels in St. Charles
St. Charles Neighborhoods
Top Points of Interests in St. Charles
- Hotels near Ameristar Casino St. Charles
- Hotels near St Charles Convention Center
- Hotels near Historic Main Street
- Hotels near Family Arena
- Hotels near Lindenwood University
- Hotels near Katy Trail
- Hotels near Fast Lane Classic Cars
- Hotels near Lewis & Clark Boathouse and Nature Center
- Hotels near First Missouri State Capitol Historic Site
- Hotels near Missouri Bluffs Golf Course
- Hotels near Weldon Spring Site Interpretive Center
- Hotels near Jaycee Park
- Hotels near St. Louis Union Station
- Hotels near Enterprise Center
- Hotels near Gateway Arch
- Hotels near Busch Stadium
- Hotels near St. Louis Zoo
- Hotels near Washington University in St. Louis
- Hotels near Forest Park
- Hotels near Dome at America’s Center
Cities near St. Charles
- Maryland Heights Hotels (6.33 mi)
- Chesterfield Hotels (9.49 mi)
- Hazelwood Hotels (6.19 mi)
- St. Peters Hotels (6.7 mi)
- Innsbrook Hotels (29.82 mi)
- O'Fallon Hotels (11 mi)
- Collinsville Hotels (28.73 mi)
- Wentzville Hotels (19.2 mi)
- Edwardsville Hotels (27.79 mi)
- Fenton Hotels (19.25 mi)
- Grafton Hotels (13.05 mi)
- Ozarks Hotels (156.82 mi)
- Alton Hotels (18.27 mi)
- Washington Hotels (31.97 mi)
- Arnold Hotels (25.37 mi)
- Brentwood Hotels (14.23 mi)
- Kirkwood Hotels (14.96 mi)
- Eureka Hotels (20.94 mi)
- Richmond Heights Hotels (14.6 mi)
- Wildwood Hotels (15.65 mi)
Car Rentals Near St. Charles
- Car rentals in Maryland Heights
- Car rentals in Chesterfield
- Car rentals in Hazelwood
- Car rentals in St. Peters
- Car rentals in Innsbrook
- Car rentals in O'Fallon
- Car rentals in Collinsville
- Car rentals in Wentzville
- Car rentals in Edwardsville
- Car rentals in Fenton
- Car rentals in Grafton
- Car rentals in Ozarks
- Car rentals in Alton
- Car rentals in Washington
- Car rentals in Arnold
- Car rentals in Brentwood
Top Spa Resort Destinations
- Annapolis Spa Hotels
- Ottawa Valley Spa Hotels
- Tallahassee Spa Hotels
- Appalachian Mountains Spa Hotels
- Corpus Christi Spa Hotels
- Raleigh Spa Hotels
- Syracuse Spa Hotels
- Chattanooga Spa Hotels
- Grand Canyon Spa Hotels
- Toledo Spa Hotels
- Edmonton Spa Hotels
- El Paso Spa Hotels
- Omaha Spa Hotels
- Cincinnati Spa Hotels
- Fargo Spa Hotels
- Des Moines Spa Hotels
- Dayton Spa Hotels
- Flagstaff Spa Hotels
- Little Rock Spa Hotels
- Waco Spa Hotels
Top Booked Hotels in St. Charles
- Ameristar Casino Resort and Spa
- Embassy Suites by Hilton St. Louis St. Charles
- Best Western Plus The Charles Hotel
- Country Inn & Suites by Radisson, St. Charles, MO
- Country Inn & Suites by Radisson, St. Peters, MO
- Hollywood Casino & Hotel St. Louis
- Hyatt Regency St. Louis at The Arch
- Clayton Plaza Hotel & Extended Stay
- The Last Hotel