Search for Cheap Deals on
Hotels in St. Ann

Check Last Minute St. Ann Hotel Deals

Tonight Apr 18 - Apr 19Next weekend Apr 24 - Apr 26

Choose from 1941 St. Ann Hotel Deals

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
  • 24 min drive from St. Louis Union Station
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (2,942 reviews)
My friend and I stayed here for 4 days and 3 nights on a girls trip. The location was perfect, within a 10-20 minute drive of everywhere we wanted to go. We were able to check in a little early which was extremely convenient for us! We were also pleasantly surprised by the hotel doing a complimentary ...

Reviewed on Apr 18, 2026

Pear Tree Inn St. Louis Airport
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

2.5 out of 5
10820 Pear Tree Lane St. Ann MO
  • 24 min drive from St. Louis Union Station
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,591 reviews)
Staff is always so friendly!! Would definitely stay here again. Room was super clean and breakfast was great, also!

Reviewed on Apr 17, 2026

Wingate by Wyndham St. Louis Airport
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
  • 13 min drive from St. Louis Union Station
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (3,155 reviews)
Front desk is extremely slow.

Reviewed on Apr 18, 2026

Clayton Plaza Hotel & Extended Stay
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
  • 16 min walk from St. Louis Union Station
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (3,381 reviews)
They had free food and drinks every afternoon we were there.

Reviewed on Apr 17, 2026

Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
  • 17 min walk from St. Louis Union Station
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,006 reviews)
Had to switch rooms due to the rooms being nasty. Rooms seemed old and outdated. Mattress, pillow, and bed spread was uncomfortable. Some elevators were out of services.

Reviewed on Apr 17, 2026

Hyatt Regency St. Louis at The Arch
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
  • 5 min walk from St. Louis Union Station
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,766 reviews)
Great location, clean rooms, wonderful pool and hot tub

Reviewed on Apr 16, 2026

21C Museum Hotel St Louis
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
  • 32 min drive from St. Louis Union Station
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (2,191 reviews)
Clean room

Reviewed on Apr 17, 2026

Hollywood Casino & Hotel St. Louis
Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

3 out of 5
201 S 20th St St. Louis MO
  • 3 min walk from St. Louis Union Station
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,360 reviews)
The room and staff was fabulous but was not told they had major interior renovations being done. It was loud full of workers and construction trucks parked everywhere. I paid for the "Best" stay for my daughter, granddaughters and a great grand baby. My health is not well at nearly 70 and wanted ...

Reviewed on Apr 17, 2026

Drury Inn & Suites St. Louis Union Station
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
  • 31 min drive from St. Louis Union Station
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,216 reviews)
The breakfast was good, the pool and hot tub were dirty looking, the water looked murky and there was stuff floating in it. We were disappointed because that's one of the reasons we booked there. The bathroom was small looked like a bathroom in a small apartment. The staff was nice, but I don't think ...

Reviewed on Apr 16, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
  • 5 min walk from St. Louis Union Station
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,947 reviews)
Located downtown adjacent but not in the hustle and bustle. We booked this hotel because it had free breakfast, free parking, and it had a hot tub. All of which were exactly what we had hoped for! Breakfast included hot options like biscuits and gravy, eggs, and sausage. There was also a soda fountain ...

Reviewed on Apr 16, 2026

Pear Tree Inn St. Louis Near Union Station
Hilton St. Louis Airport

Hilton St. Louis Airport

3.5 out of 5
10330 Natural Bridge Rd St. Louis MO
  • 23 min drive from St. Louis Union Station
Book a stay at this business-friendly hotel in St. Louis. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
7.6/10 Good! (1,001 reviews)
.

Reviewed on Apr 16, 2026

Hilton St. Louis Airport
Best Western St. Louis-Kirkwood Route 66

Best Western St. Louis-Kirkwood Route 66

3.5 out of 5
1200 S Kirkwood Road Kirkwood MO
  • 24 min drive from St. Louis Union Station
Book a stay at this business-friendly hotel in Kirkwood. Enjoy free parking, an outdoor pool, and room service. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,439 reviews)
Rooms need a LOT of updating. Older hotel with ok amenities. Heat/Air conditioning unit did not work at all. Booked us in a room that was already occupied by another family. I always enjoy walking into someone else’s room. Hotel fixed it, but still very unsettling.

Reviewed on Apr 18, 2026

Best Western St. Louis-Kirkwood Route 66
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in St. Ann

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your St. Ann hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in St. Ann.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of St. Ann’s 1,941 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $103. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great St. Ann hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in St. Ann. No matter your reason for visiting St. Ann, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About St. Ann hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in St. Ann for as low as $103.

How many hotels are there in St. Ann?

With over 1,941 hotels in St. Ann, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $103.

How to find cheap car rentals in St. Ann?

Finding a cheap car rental deal in St. Ann is as easy as scoring cheap hotels in St. Ann. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.