Hotels Near
St. Charles Historic District

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Featured St. Charles Historic District Hotels

Country Inn & Suites by Radisson, St. Charles Historic District
Country Inn & Suites by Radisson, St. Charles Historic District
2.5 out of 5
1190 S Main St, St. Charles, MO
Fully refundable
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,005 reviews)
"A great hotel, convenient to the old St. Charles shopping :)"

Reviewed on Jan 20, 2025

Country Inn & Suites by Radisson, St. Charles Historic District
Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,776 reviews)
"Jacuzzi in the suite was a nice touch"

Reviewed on Jan 20, 2025

Hollywood Casino & Hotel St. Louis
Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,948 reviews)
"room was very nice... parkiing deck is a maze as always.... breakfast was not quite as good as i'd remembered it. same stuff every day. oatmeal was at the bottom of the pot... omelette was very good though, as always"

Reviewed on Jan 21, 2025

Clayton Plaza Hotel & Extended Stay
21C Museum Hotel St Louis
21C Museum Hotel St Louis
4.5 out of 5
1528 Locust street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (909 reviews)
perfect for couples
"We stayed at 21C for an overnight getaway. The check in was seamless- the staff was very friendly. Our room was beautiful and clean (was missing body wash but it was quickly rectified). The robes were luxurious, a really nice touch. We enjoyed all of the amenities at the hotel; the pool, hot tub ..."

Reviewed on Jan 18, 2025

21C Museum Hotel St Louis
The Last Hotel
The Last Hotel
4.5 out of 5
1501 Washington Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the pool and the ...
7.8/10 Good! (1,172 reviews)
"Loved the hotel and the atmosphere"

Reviewed on Jan 19, 2025

The Last Hotel
Sonesta ES Suites St. Louis - Chesterfield
Sonesta ES Suites St. Louis - Chesterfield
3 out of 5
15431 Conway Rd, Chesterfield, MO
Fully refundableReserve now, pay when you stay
Stay at this hotel in Chesterfield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,007 reviews)
Clean and quiet
"Room was very nice and clean. The bed was fantastic, full kitchen. And very spacious. The only problem was no restaurants close by"

Reviewed on Jan 19, 2025

Sonesta ES Suites St. Louis - Chesterfield
St. Louis Union Station Hotel, Curio Collection by Hilton
St. Louis Union Station Hotel, Curio Collection by Hilton
4 out of 5
1820 Market Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Book a stay at this historic hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 7 restaurants. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,000 reviews)
"A lot of history at Union Station that makes for a great atmosphere. And easy to relax due to the staff and how well maintained and clean everything is."

Reviewed on Jan 19, 2025

St. Louis Union Station Hotel, Curio Collection by Hilton
Moonrise Hotel
Moonrise Hotel
4 out of 5
6177 Delmar Blvd, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...
9/10 Wonderful! (1,633 reviews)
"If you’re seeing a show at the Pageant, the moonrise is a must"

Reviewed on Jan 18, 2025

Moonrise Hotel
Pear Tree Inn St. Louis Near Union Station
Pear Tree Inn St. Louis Near Union Station
3 out of 5
2211 Market Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,381 reviews)
Fantastic experience!
"It was heaven to walk into a clean, quiet room. Comfortable beds, for sure. Wonderful front desk staff the night we checked in and the morning we checked out. Complete, delicious breakfast. I could go on and on! Highly recommend this hotel."

Reviewed on Jan 19, 2025

Pear Tree Inn St. Louis Near Union Station
La Quinta Inn & Suites by Wyndham St. Louis Westport
La Quinta Inn & Suites by Wyndham St. Louis Westport
2.5 out of 5
11805 Lackland Rd, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.2/10 Good! (1,000 reviews)
"…"

Reviewed on Jan 10, 2025

La Quinta Inn & Suites by Wyndham St. Louis Westport
Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Airport
2.5 out of 5
10810 Pear Tree Ln, St. Ann, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (2,495 reviews)
"Perfect option for a good night's sleep and shuttle service early in the morning."

Reviewed on Jan 20, 2025

Pear Tree Inn St. Louis Airport
Live by Loews - St.Louis
Live by Loews - St.Louis
4 out of 5
799 Clark ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
9/10 Wonderful! (1,004 reviews)
"Love this hotel"

Reviewed on Jan 18, 2025

Live by Loews - St.Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in St. Charles Historic District

St. Louis is a city that has a lot going on, but you have your sights set on St. Charles Historic District. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that St. Charles Historic District has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of St. Charles Historic District hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of St. Louis so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the St. Charles Historic District underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the St. Charles Historic District city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of St. Charles Historic District cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in St. Charles Historic District at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $87
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the St. Charles Historic District hotel you want, book it, and never look back. Because your great escape is ahead of you.