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4 Star Hotels in St. Charles

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Featured 4 Star St. Charles Hotels

Hyatt Regency St. Louis at The Arch
4 out of 5
  • 36 min drive from Ameristar Casino St. Charles
The price is $105 per night from Nov 28 to Nov 29
$105
includes taxes & fees
Nov 28 - Nov 29
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Hyatt Regency St. Louis at The Arch
Renaissance St. Louis Airport Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 13 min drive from Ameristar Casino St. Charles
The price is $135 per night from Dec 6 to Dec 7
$135
includes taxes & fees
Dec 6 - Dec 7
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
Renaissance St. Louis Airport Hotel
The Last Hotel
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 34 min drive from Ameristar Casino St. Charles
The price is $117 per night from Dec 12 to Dec 13
$117
includes taxes & fees
Dec 12 - Dec 13
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and valet parking (surcharge). Our guests praise the pool and the ...
The Last Hotel
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St. Louis Union Station Hotel, Curio Collection by Hilton
4 out of 5
Fully refundableReserve now, pay when you stay
  • 34 min drive from Ameristar Casino St. Charles
The price is $191 per night from Dec 3 to Dec 4
$191
includes taxes & fees
Dec 3 - Dec 4
Book a stay at this historic hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 7 restaurants. Our guests praise the helpful staff and the clean rooms ...
St. Louis Union Station Hotel, Curio Collection by Hilton
Le Méridien St. Louis Clayton
4 out of 5
Fully refundableReserve now, pay when you stay
  • 24 min drive from Ameristar Casino St. Charles
The price is $178 per night from Nov 29 to Nov 30
$178
includes taxes & fees
Nov 29 - Nov 30
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Le Méridien St. Louis Clayton
The Cheshire
4 out of 5
Fully refundableReserve now, pay when you stay
  • 28 min drive from Ameristar Casino St. Charles
The price is $153 per night from Dec 1 to Dec 2
$153
includes taxes & fees
Dec 1 - Dec 2
Book a stay at this boutique hotel in Richmond Heights. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
The Cheshire
21C Museum Hotel St Louis
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 34 min drive from Ameristar Casino St. Charles
The price is $133 per night from Dec 1 to Dec 2
$133
includes taxes & fees
Dec 1 - Dec 2
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
21C Museum Hotel St Louis
Ameristar Casino Resort and Spa
4.5 out of 5
  • 1 min walk from Ameristar Casino St. Charles
The price is $203 per night from Dec 1 to Dec 2
$203
includes taxes & fees
Dec 1 - Dec 2
Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 5 restaurants. Our guests praise the clean rooms and the property ...
Ameristar Casino Resort and Spa
Live by Loews - St.Louis
4 out of 5
Fully refundableReserve now, pay when you stay
  • 36 min drive from Ameristar Casino St. Charles
The price is $172 per night from Dec 23 to Dec 24
$172
includes taxes & fees
Dec 23 - Dec 24
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
Live by Loews - St.Louis
Moonrise Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 25 min drive from Ameristar Casino St. Charles
The price is $151 per night from Nov 28 to Nov 29
$151
includes taxes & fees
Nov 28 - Nov 29
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...
Moonrise Hotel
River City Casino & Hotel
4 out of 5
  • 45 min drive from Ameristar Casino St. Charles
The price is $137 per night from Dec 1 to Dec 2
$137
includes taxes & fees
Dec 1 - Dec 2
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
River City Casino & Hotel
DoubleTree by Hilton St. Louis Forest Park
4 out of 5
Fully refundableReserve now, pay when you stay
  • 29 min drive from Ameristar Casino St. Charles
The price is $171 per night from Nov 29 to Nov 30
$171
includes taxes & fees
Nov 29 - Nov 30
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
DoubleTree by Hilton St. Louis Forest Park
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4-star hotels in St. Charles

When you want to live it up, but not bust your bank account, then there’s nothing better than a 4-star hotel in St. Charles for your next trip. You’ll get all the amenities you can think of (and then some) at a rate within your means.

No fault in our stars

So what’s with the star rating anyway? Good question. The star rating has little to do with the price, and more to do with the amenities. 4-Star hotels in St. Charles as well as everywhere else, usually have all those thoughtful touches that make you go “Ooh,” “Ahh,” and ”YES!” Think amenities like luxury bedding, high-end electronics, concierge service, and restaurants that make eating in a gourmet experience.

Stars that shine

You know there are as many underground spots, inviting lounges, memory-making music venues as there are stars in the sky. But you’ll need the funds to check them all off. That’s why we give you the chance to take us up on the Hotwire Hot Rate. You can snag St. Charles 4-star hotels and still have plenty of leftover cash to paint the town whatever color you want. Filter hotels by:

  • Hotwire Hot Rate: We’ll snag you a crazy deal on a room by finding your hotel name after you book.
  • Price: You know that paying full price is for suckers? You can get a cheap 4-star hotel in St. Charles starting at $105 per night.
  • Amenities: What makes you flip for your trip? Full-service spa? Heated pool? 24-hour room service? Get a hotel that’ll send you over the moon.

Do you deserve a swanky hotel with a ton of amenities? Yes, yes you do. And you also deserve a sweet deal on it. Book with Hotwire today and get that star-studded St. Charles 4-star hotel and have plenty of cash left over to spend at that secret super star joint in the city.