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4 Star Hotels in St. Louis

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Featured 4 Star St. Louis Hotels

Hyatt Regency St. Louis at The Arch
4 out of 5
Fully refundableReserve now, pay when you stay
  • 7 min walk from Busch Stadium
The price is $133 per night from Mar 9 to Mar 10
$133
includes taxes & fees
Mar 9 - Mar 10
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Hyatt Regency St. Louis at The Arch
21C Museum Hotel St Louis
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 15 min walk from Busch Stadium
The price is $193 per night from Mar 16 to Mar 17
$193
includes taxes & fees
Mar 16 - Mar 17
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
21C Museum Hotel St Louis
River City Casino & Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 17 min drive from Busch Stadium
The price is $133 per night from Mar 2 to Mar 3
$133
includes taxes & fees
Mar 2 - Mar 3
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
River City Casino & Hotel
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St. Louis Union Station Hotel, Curio Collection by Hilton
4 out of 5
Fully refundableReserve now, pay when you stay
  • 15 min walk from Busch Stadium
The price is $227 per night from Mar 9 to Mar 10
$227
includes taxes & fees
Mar 9 - Mar 10
Book a stay at this historic hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 7 restaurants. Our guests praise the helpful staff and the clean rooms ...
St. Louis Union Station Hotel, Curio Collection by Hilton
Moonrise Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 12 min drive from Busch Stadium
The price is $151 per night from Mar 2 to Mar 3
$151
includes taxes & fees
Mar 2 - Mar 3
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...
Moonrise Hotel
DoubleTree by Hilton St. Louis Airport
4 out of 5
Fully refundableReserve now, pay when you stay
  • 24 min drive from Busch Stadium
The price is $124 per night from Mar 6 to Mar 7
$124
includes taxes & fees
Mar 6 - Mar 7
Stay at this 4-star family-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
DoubleTree by Hilton St. Louis Airport
The Cheshire
4 out of 5
Fully refundableReserve now, pay when you stay
  • 12 min drive from Busch Stadium
The price is $172 per night from Mar 3 to Mar 4
$172
includes taxes & fees
Mar 3 - Mar 4
Stay at this 4-star boutique hotel in Richmond Heights. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
The Cheshire
Renaissance St. Louis Airport Hotel
4 out of 5
Fully refundableReserve now, pay when you stay
  • 23 min drive from Busch Stadium
The price is $135 per night from Mar 21 to Mar 22
$135
includes taxes & fees
Mar 21 - Mar 22
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
Renaissance St. Louis Airport Hotel
Live by Loews - St.Louis
4 out of 5
Fully refundableReserve now, pay when you stay
  • 3 min walk from Busch Stadium
The price is $177 per night from Mar 2 to Mar 3
$177
includes taxes & fees
Mar 2 - Mar 3
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
Live by Loews - St.Louis
Embassy Suites by Hilton St. Louis Downtown
4 out of 5
Fully refundableReserve now, pay when you stay
  • 12 min walk from Busch Stadium
The price is $129 per night from Mar 9 to Mar 10
$129
includes taxes & fees
Mar 9 - Mar 10
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free breakfast, a fitness center, and WiFi (surcharge). Our guests praise the breakfast and the ...
Embassy Suites by Hilton St. Louis Downtown
Ameristar Casino Resort and Spa
4.5 out of 5
Fully refundableReserve now, pay when you stay
  • 36 min drive from Busch Stadium
The price is $214 per night from Mar 9 to Mar 10
$214
includes taxes & fees
Mar 9 - Mar 10
Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms and the property ...
Ameristar Casino Resort and Spa
DoubleTree by Hilton St. Louis Forest Park
4 out of 5
Fully refundableReserve now, pay when you stay
  • 7 min drive from Busch Stadium
The price is $176 per night from Mar 9 to Mar 10
$176
includes taxes & fees
Mar 9 - Mar 10
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
DoubleTree by Hilton St. Louis Forest Park
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4-Star Hotels in St. Louis

When you want to live it up, but not bust your bank account, it's time to look into a 4-star hotel in St. Louis for your next vacation. You'll get all the perks you can think of (and more) at a rate within your budget. Catch some Zs on high thread-count sheets, work on your tan by the picturesque pool, expand your palate at a world-class restaurant, take a break from it all at the in-house spa ... All this and more is at your fingertips at St. Louis 4-star hotels.

No fault in our stars

So what's the star rating about anyway? Here's the deal: Star rating doesn't have a lot to do with the price, and way more to do with the glowing amenities. 4-star hotels in St. Louis, Missouri, and everywhere else, usually have all those fancy touches that make you say "Oh," "Wow," and "YES!" Expect perks like personalized concierge services, the latest electronics, luxe bed linens, and restaurants that make eating in a foodie's dream.

Stars in your eyes

You want to live it up on your vacation, but you also know that every dollar you don't spend on your 4-star hotel in St. Louis is an extra one that you can spend out on the town. And, with all there is to do in St. Louis you'll need every last cent. Thankfully, Hotwire has the Hotwire Hot Rate to get you the best bargains, helping you save on our top hotels at the click of a mouse. Finding the right hotel for your trip is important, but it shouldn't be something to stress over. We've made it a snap to find the hotel of your dreams. Filter the best 4-star hotels in St. Louis by:

  • Hotwire Hot Rate: In search of the best deals on the net? Let us pick your hotel. We'll tell you which hotel after you make your reservations, and the savings and accommodations will be spectacular.
  • Price: You're aware that paying full price is for chumps? You can get a cheap 4-star hotel in St. Louis starting at $124 per night.
  • Amenities: What makes your vacation wishes come true? 24-hour room service? Heated pool? Full-service spa? Get a hotel that'll send you over the moon.

You deserve it all. Perks galore and the freshest spot to press reset in St. Louis without blowing all of your fun money. When you book a Hotwire Hot Rate, you get that stellar St. Louis 4-star hotel and have cash left to check off everything on your to-do list on your superstar vacay. Hotwire has 1,888 St. Louis hotels to choose from, but the most popular rooms aren't available long so book your stay today.