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Hotels in O'Fallon

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Choose from 1421 O'Fallon Hotel Deals

Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

2 out of 5
1100 Eastgate Dr O'Fallon IL
  • 5 min drive from Scott Air Force Base
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,003 reviews)
Very dirty, insects crawling around. Lights did not work in room.

Reviewed on Apr 24, 2026

Super 8 by Wyndham O'Fallon
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

3 out of 5
1118 Central Park Drive O'Fallon IL
  • 8 min drive from Scott Air Force Base
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,003 reviews)
Clean room and bathroom. Excellent customer service. Wonderful breakfast and dinner. Nice and well maintained pool facilities. Recommend 10/10.

Reviewed on Apr 22, 2026

Drury Inn & Suites St. Louis O'Fallon, IL
Quality Inn O'Fallon IL - St. Louis

Quality Inn O'Fallon IL - St. Louis

3 out of 5
1409 W US 50 O'Fallon IL
  • 12 min drive from Scott Air Force Base
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (1,002 reviews)
Good location easy to check in and out

Reviewed on Apr 26, 2026

Quality Inn O'Fallon IL - St. Louis
Welcome Suites

Welcome Suites

2 out of 5
148 Regency Park O'Fallon IL
  • 10 min drive from Scott Air Force Base
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free WiFi, free parking, and a fitness center. Popular attractions O'Fallon Family Sports Park ...
5.6/10 (240 reviews)
When we checked in we were given a room with one bed When we reserved a 2 bed room. When we got to the room ( it's supposed to be an extended stay with a stove, fridge and a microwave). The fridge was an apartment size which was ok and microwave was ok but the cook top in the counter and the range ...

Reviewed on Apr 26, 2026

Welcome Suites
Sleep Inn O'Fallon near I-64

Sleep Inn O'Fallon near I-64

2.5 out of 5
140 Venita Dr O'Fallon IL
  • 11 min drive from Scott Air Force Base
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (942 reviews)
The front lobby smelled like weed. Garbage lined the hallway where our room was. The flooring was extremely dirty. Doors, doorframes, and walls were covered in dirt and handprints. I didn’t even want to take my shoes off and walk around the room. We found dog food on the floor in our room. If we ...

Reviewed on Apr 25, 2026

Sleep Inn O'Fallon near I-64
Baymont by Wyndham O'Fallon St. Louis Area

Baymont by Wyndham O'Fallon St. Louis Area

2.5 out of 5
1320 Park Plaza Drive O'Fallon IL
  • 10 min drive from Scott Air Force Base
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Popular attractions O'Fallon Family Sports Park and ...
5.6/10 (472 reviews)
Toilet in room 104 runs intermittently. I reported it when we checked in and nothing was done to fix it. I reported again when we checked out.

Reviewed on Apr 25, 2026

Baymont by Wyndham O'Fallon St. Louis Area
Comfort Inn & Suites O'Fallon - St. Louis Area

Comfort Inn & Suites O'Fallon - St. Louis Area

2 out of 5
116 Regency Park O'Fallon IL
  • 10 min drive from Scott Air Force Base
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.4/10 (139 reviews)
The staff was helpful, the room was relatively clean. The property is clearly old and has some issues with disrepair that could be addressed. It was good for what it was.

Reviewed on Apr 25, 2026

Comfort Inn & Suites O'Fallon - St. Louis Area
Holiday Inn Express & Suites O'Fallon/Shiloh by IHG

Holiday Inn Express & Suites O'Fallon/Shiloh by IHG

2.5 out of 5
3396 Green Mount Crossing Drive Shiloh O'Fallon IL
  • 7 min drive from Scott Air Force Base
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (597 reviews)
The room was clean and the staff were very nice and helpful. Parking was very good. Breakfast was good but options were limited.

Reviewed on Apr 26, 2026

Holiday Inn Express & Suites O'Fallon/Shiloh by IHG
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
  • 36 min drive from Scott Air Force Base
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,017 reviews)
Clean room

Reviewed on Apr 26, 2026

Hyatt Regency St. Louis at The Arch
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
  • 38 min drive from Scott Air Force Base
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,789 reviews)
The rooms are super clean, and modern! Very nice amenities all around! With 2 restaurants and the bar on cots it's very ideal for relaxing after a long day of work or walking around the city! We will be back for sure!

Reviewed on Apr 26, 2026

21C Museum Hotel St Louis
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
  • 36 min drive from Scott Air Force Base
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (3,390 reviews)
Had a great time, definitely will be coming back!!!

Reviewed on Apr 26, 2026

Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
  • 39 min drive from Scott Air Force Base
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,949 reviews)
It is a nice hotel and convenient for what we needed. The room was clean just a little outdated. The staff was friendly and breakfast was good.

Reviewed on Apr 26, 2026

Pear Tree Inn St. Louis Near Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in O'Fallon

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $66. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great O'Fallon hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in O'Fallon. No matter your reason for visiting O'Fallon, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About O'Fallon hotels

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How many hotels are there in O'Fallon?

With over 1,421 hotels in O'Fallon, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $66.

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