Search for Cheap Deals on
Hotels in Southern Illinois

Check Last Minute Southern Illinois Hotel Deals

Tonight Sep 24 - Sep 25Next weekend Sep 29 - Oct 1

Choose from 840 Southern Illinois Hotel Deals

Super 8 by Wyndham O'Fallon
Super 8 by Wyndham O'Fallon
2 out of 5
1100 Eastgate Dr, O'Fallon, IL
  • 4 hours drive from Shawnee National Forest
The price is $52 per night from Oct 2 to Oct 3
$52
per night
Oct 2 - Oct 3
Stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Scott Air Force Base and O'Fallon Family ...
7.6/10 Good! (1,001 reviews)
"Good and respectful staff"

Reviewed on Aug 20, 2023

Super 8 by Wyndham O'Fallon
Baymont by Wyndham Marion
Baymont by Wyndham Marion
2.5 out of 5
2608 W Main St, Marion, IL
  • 1 hour drive from Shawnee National Forest
The price is $71 per night from Sep 26 to Sep 27
$71
per night
Sep 26 - Sep 27
Stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Rent One Park and Kokopelli Golf Club ...
8/10 Very Good! (1,009 reviews)
"Would really appreciate scrambled eggs & sausage in the mornings!!'"

Reviewed on Sep 24, 2023

Baymont by Wyndham Marion
Ramada by Wyndham Effingham
Ramada by Wyndham Effingham
3 out of 5
1606 W Fayette Avenue, Effingham, IL
  • 4 hours drive from Shawnee National Forest
The price is $61 per night from Oct 9 to Oct 10
$61
per night
Oct 9 - Oct 10
Stay at this 3-star business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Lake Sara and Cross at the Crossroads ...
7.8/10 Good! (573 reviews)
"Friendly staff"

Reviewed on Sep 9, 2023

Ramada by Wyndham Effingham
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
2.5 out of 5
136 Regency Park, O'Fallon, IL
  • 4 hours drive from Shawnee National Forest
The price is $60 per night from Sep 25 to Sep 26
$60
per night
Sep 25 - Sep 26
Stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Popular attractions O'Fallon Family Sports Park and St. ...
7/10 Good! (1,002 reviews)
"I like this hotel"

Reviewed on Sep 19, 2023

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
Drury Inn & Suites Mt. Vernon
Drury Inn & Suites Mt. Vernon
3 out of 5
145 North 44th Street , Mount Vernon, IL
  • 2 hours drive from Shawnee National Forest
The price is $117 per night from Oct 4 to Oct 5
$117
per night
Oct 4 - Oct 5
Stay at this 3-star business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the quiet rooms and the property ...
9.4/10 Exceptional! (1,004 reviews)
"Perhaps the cleanest, most well maintained Drury Inn I have been in!"

Reviewed on Sep 22, 2023

Drury Inn & Suites Mt. Vernon
Town & Country Inn
Town & Country Inn
2 out of 5
910 Cherry Ln, Troy, IL
  • 4 hours drive from Shawnee National Forest
The price is $75 per night from Sep 25 to Sep 26
$75
per night
Sep 25 - Sep 26
Stay at this motel in Troy. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Villa Marie Winery & Banquet Center and Edwardsville Arts ...
8.6/10 Excellent! (49 reviews)
"Very kind and friendly people. Clean, comfortable room."

Reviewed on Sep 18, 2023

Town & Country Inn
Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites St. Louis O'Fallon, IL
3 out of 5
1118 Central Park Drive, O'Fallon, IL
  • 4 hours drive from Shawnee National Forest
The price is $108 per night from Oct 22 to Oct 23
$108
per night
Oct 22 - Oct 23
Stay at this 3-star business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Popular attractions O'Fallon Family Sports Park and ...
9.4/10 Exceptional! (1,001 reviews)
"Good"

Reviewed on Sep 17, 2023

Drury Inn & Suites St. Louis O'Fallon, IL
Comfort Suites Mount Vernon
Comfort Suites Mount Vernon
2.5 out of 5
404 South 44th Street, Mount Vernon, IL
  • 2 hours drive from Shawnee National Forest
The price is $115 per night from Oct 22 to Oct 23
$115
per night
Oct 22 - Oct 23
Stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our reviews. ...
8.6/10 Excellent! (1,002 reviews)
"I can’t say enough about our stay! This is the best hotel we’ve ever stayed at. Everything was fantastic! Even the pool and hot tub were wonderful! My children and I enjoyed our stay and we will be staying here again!"

Reviewed on Sep 18, 2023

Comfort Suites Mount Vernon
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
2.5 out of 5
6 Gateway Dr, Collinsville, IL
  • 4 hours drive from Shawnee National Forest
The price is $84 per night from Oct 2 to Oct 3
$84
per night
Oct 2 - Oct 3
Stay at this business-friendly hotel in Collinsville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Gateway Conference Center and Splash ...
7.2/10 Good! (1,001 reviews)
"Clean hotel. Only bad thing is pool is closed for the season. It’s still 80 out."

Reviewed on Sep 20, 2023

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
Best Western Troy Hotel
Best Western Troy Hotel
2.5 out of 5
2020 Formosa Drive, Troy, IL
  • 4 hours drive from Shawnee National Forest
The price is $89 per night from Oct 1 to Oct 2
$89
per night
Oct 1 - Oct 2
Stay at this business-friendly hotel in Troy. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Villa Marie Winery & Banquet Center and ...
8/10 Very Good! (636 reviews)
"Was clean and comfortable."

Reviewed on Sep 23, 2023

Best Western Troy Hotel
La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham Effingham
2.5 out of 5
1103 Avenue Of Mid America, Effingham, IL
  • 4 hours drive from Shawnee National Forest
The price is $108 per night from Oct 15 to Oct 16
$108
per night
Oct 15 - Oct 16
Stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our reviews. ...
8.8/10 Excellent! (1,004 reviews)
"Room spacious , clean would recommend"

Reviewed on Sep 24, 2023

La Quinta Inn & Suites by Wyndham Effingham
Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites St. Louis Fairview Heights
3 out of 5
12 Ludwig Dr, Fairview Heights, IL
  • 4 hours drive from Shawnee National Forest
The price is $112 per night from Oct 3 to Oct 4
$112
per night
Oct 3 - Oct 4
Stay at this 3-star business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition ...
9/10 Wonderful! (1,001 reviews)
"Just a one night stop but was very happy. Breakfast was phenomenal!! 5 sta!"

Reviewed on Sep 23, 2023

Drury Inn & Suites St. Louis Fairview Heights
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Southern Illinois

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Southern Illinois hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southern Illinois.

Choosing the right hotel in Illinois has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southern Illinois’s 840 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $52. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Southern Illinois hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southern Illinois. No matter your reason for visiting Southern Illinois, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southern Illinois hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Southern Illinois for as low as $52.

How many hotels are there in Southern Illinois?

With over 840 hotels in Southern Illinois, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $52.

How to find cheap car rentals in Southern Illinois?

Finding a cheap car rental deal in Southern Illinois is as easy as scoring cheap hotels in Southern Illinois. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Southern Illinois now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Southern Illinois right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.