Search for Cheap Deals onHotels in Southern Illinois
Choose from 1182 Southern Illinois Hotel Deals
Drury Inn & Suites St. Louis Fairview Heights
I have never stayed at a hotel that serves a complimentary breakfast and dinner. 5 stars. Everything was wonderful.
Reviewed on Apr 3, 2026
Best Western Delta Inn
The breakfast was light but good
Reviewed on Mar 31, 2026
Drury Inn & Suites St. Louis O'Fallon, IL
Hotel is in a great location. There is a lot to do in the area (shopping, eating, etc.). The staff were pleasant and helpful. The breakfast was one of the best I've seen in travel. It was fresh, tasty, and hot. Sadly, one of the elevators was out of service and so was our ice machine. For such a ...
Reviewed on Apr 4, 2026
Drury Plaza Hotel Mt. Vernon
The room was clean. We were able to get plenty to eat. The staff was nice.
Reviewed on Apr 4, 2026
Comfort Suites Mount Vernon
Yesu
Reviewed on Apr 2, 2026
Super 8 by Wyndham O'Fallon
The breakfast doors did not open until 7 AM. We left before it openned. AC Was L0UD!
Reviewed on Apr 4, 2026
Baymont by Wyndham Effingham
Place was clean, staff were nice.
Reviewed on Apr 5, 2026
Quality Inn O'Fallon IL - St. Louis
The hotel was so beautiful and so nice inside the room was clean. The bed was freshly made. Everything smelled good clean refreshing what I really enjoyed. The most was the hot tub. It was so relaxing. I would definitely come back again. I honestly did not want to leave. That’s how much fun I had ...
Reviewed on Mar 29, 2026
Comfort Suites Fairview Heights - St. Louis
The Health Department had a notice on the pool shutting it down due to multiple unsafe conditions. No one answered the phone as we called before our visit so there was no way to check on the pool. The elevator was suspect and the elevator safety inspection had expired 11 months ago. Poor breakfast ...
Reviewed on Apr 4, 2026
Drury Inn & Suites Marion
Very nice place to stay, easy to get to, great happy hour/meal as well as breakfast!
Reviewed on Apr 4, 2026
Red Lion Inn & Suites Pontoon Beach
Hotel is clean and quiet. Breakfast selection is very limited
Reviewed on Apr 2, 2026
Holiday Inn Express Metropolis by IHG
Convenient, also had nice breakfast.
Reviewed on Apr 3, 2026
Find cheap hotels in Southern Illinois
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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Southern Illinois.
Choosing the right hotel in Illinois has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Southern Illinois’s 1,182 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $62. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Southern Illinois hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southern Illinois. No matter your reason for visiting Southern Illinois, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About Southern Illinois hotels
Where can I find the best last-minute travel deals?
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How many hotels are there in Southern Illinois?
With over 1,182 hotels in Southern Illinois, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $62.
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- Hotels near Shawnee National Forest
- Hotels near Southern Illinois University
- Hotels near Harrah's Metropolis
- Hotels near Garden of the Gods Recreation Area
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