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Hotels in Perryville

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Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

2.5 out of 5
2020 Jefferson St Perryville MO
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (532 reviews)
Tv is slanted on the wall

Reviewed on Nov 22, 2025

Holiday Inn Express & Suites Perryville by IHG
Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville

2 out of 5
1119 Vincent Dr Perryville MO
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly motel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (935 reviews)
The room and common area was very clean and attractive. But breakfast was a big disapp ointment. Maybe they ran out of bacon or sausage but it wasn't refilled so all of this left and 8:30 was waffles cereal and scrambled eggs.

Reviewed on Dec 1, 2025

Super 8 by Wyndham Perryville
Quality Inn Perryville I-55

Quality Inn Perryville I-55

2.5 out of 5
1517 S. Perryville Blvd. Perryville MO
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
Stay at this hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Perryville Country Club and Saint Marys Lake are located ...
6.6/10 (124 reviews)
This was an overnight trip…Our bathroom was dirty and there weren’t any extra towels or toilet paper in the room. Also the fire alarm went off at 6am without an explanation..They offered yogurt but didn’t have the key to the cabinet.

Reviewed on Aug 11, 2025

Quality Inn Perryville I-55
Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville

2 out of 5
1500 Liberty Street Perryville MO
  • 27 min walk from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Perryville Country Club and ...
6.8/10 (415 reviews)
Clean

Reviewed on Oct 13, 2025

Days Inn by Wyndham Perryville
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (655 reviews)
friendly staff and very clean

Reviewed on Nov 28, 2025

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane Jackson MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (1,009 reviews)
Most welcoming staff I have ever experienced. From the moment we checked in until the moment we left- everyone we encountered was friendly, helpful and made us feel like we were prominent guests (including our dog!) My husband and I had been traveling all day and checked in at 6:50pm - the free evening ...

Reviewed on Nov 28, 2025

Drury Inn & Suites Jackson MO
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

2.5 out of 5
2520 Veterans Memorial Dr Cape Girardeau MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
Stay at this hotel in Cape Girardeau. Enjoy free breakfast, free parking, and a fitness center. Popular attractions Cape Girardeau Conservation Nature Center ...
9.6/10 Exceptional! (95 reviews)
Excellent service and Mia was outstanding.

Reviewed on Nov 28, 2025

Tru By Hilton Cape Girardeau
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 out of 5
120 MUDDY MONSTER ROAD Murphysboro IL
  • 2 hours drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Murphysboro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (507 reviews)
Room was spotless. Enjoyed our stay!

Reviewed on Nov 30, 2025

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG

2.5 out of 5
1301 N Market St Sparta IL
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Sparta. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (367 reviews)
Staff was awesome!

Reviewed on Nov 3, 2025

Holiday Inn Express Hotel & Suites Sparta by IHG
Microtel Inn & Suites by Wyndham Sainte Genevieve

Microtel Inn & Suites by Wyndham Sainte Genevieve

2.5 out of 5
21958 Hwy 32 Ste Genevieve MO
  • 49 min drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Ste Genevieve. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (610 reviews)
very clean

Reviewed on Nov 29, 2025

Microtel Inn & Suites by Wyndham Sainte Genevieve
Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL

2.5 out of 5
2150 State Street Chester IL
  • 35 min drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Chester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (346 reviews)
Bed was ok. Staff was nice

Reviewed on Nov 9, 2025

Baymont by Wyndham Chester IL
Madison Inn Lodge

Madison Inn Lodge

2.5 out of 5
730 Plaza Drive Fredericktown MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly motel in Fredericktown. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in ...
7.4/10 Good! (296 reviews)
Room was not exactly smelling nice, but room was clean and comfortable. The lodge was close to expressway and shopping. Staff was very friendly. I would stay there again.

Reviewed on Oct 13, 2025

Madison Inn Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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