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Hotels in Perryville

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Tonight May 18 - May 19Next weekend May 24 - May 26

Choose from 123 Perryville Hotel Deals

Days Inn by Wyndham Perryville
Days Inn by Wyndham Perryville
2 out of 5
1500 Liberty Street, Perryville, MO
  • 27 min walk from National Shrine of Our Lady of the Miraculous Medal
The price is $60 per night from May 19 to May 20
$60
per night
May 19 - May 20
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Perryville Country Club and ...
6.8/10 (348 reviews)
"Curtains were dirty and falling down in the room. Breakfast very limited and had to ask for coffee no tea available"

Reviewed on May 14, 2024

Days Inn by Wyndham Perryville
Super 8 by Wyndham Perryville
Super 8 by Wyndham Perryville
2 out of 5
1119 Vincent Dr, Perryville, MO
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
The price is $64 per night from May 26 to May 27
$64
per night
May 26 - May 27
Book a stay at this business-friendly motel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (736 reviews)
"I stay here very often its a great place"

Reviewed on May 9, 2024

Super 8 by Wyndham Perryville
Holiday Inn Express & Suites Perryville, an IHG Hotel
Holiday Inn Express & Suites Perryville, an IHG Hotel
2.5 out of 5
2020 Jefferson St, Perryville, MO
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
The price is $103 per night from May 21 to May 22
$103
per night
May 21 - May 22
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (386 reviews)
"Clean property, friendly staff, nice clean rooms and comfy bed"

Reviewed on May 11, 2024

Holiday Inn Express & Suites Perryville, an IHG Hotel
Quality Inn
Quality Inn
2.5 out of 5
1517 S. Perryville Blvd., Perryville, MO
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
The price is $72 per night from Jun 2 to Jun 3
$72
per night
Jun 2 - Jun 3
Stay at this hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Perryville Country Club and National Shrine of Our Lady ...
6.4/10 (70 reviews)
"No elevator"

Reviewed on Apr 9, 2024

Quality Inn
Urban Lofts
Urban Lofts
3 out of 5
102 N Jackson St, Perryville, MO
  • 5 min drive from National Shrine of Our Lady of the Miraculous Medal
The price is $144 per night from Jun 14 to Jun 15
$144
per night
Jun 14 - Jun 15
Stay at this 3-star aparthotel in Perryville. Enjoy free WiFi, free parking, and dry cleaning or laundry services. Popular attractions Perryville Country Club ...
8.8/10 Excellent! (13 reviews)
"Loved the loft, nice decor and very clean. The only negative would be that there was supposed to be a foldout couch and sadly there was not. Two of us slept in a recliner couch, not my best night of sleep."

Reviewed on May 9, 2024

Urban Lofts
'the Brewer Guesthouse' Tiny Home w/ Patio & Yard!
'the Brewer Guesthouse' Tiny Home w/ Patio & Yard!
3.5 out of 5
Perryville
  • 10 min drive from National Shrine of Our Lady of the Miraculous Medal
Stay at this 3.5-star cottage in Perryville. Enjoy free parking, patios, and air conditioning. Popular attractions Missouri's National Veterans Memorial and ...
10/10 Exceptional! (1 review)
Had a great stay
"The house and host were just awesome, enjoyed our stay Toni even helped me Extend!! Would def stay again:)"

Reviewed on Jul 29, 2023

'the Brewer Guesthouse' Tiny Home w/ Patio & Yard!
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
2.5 out of 5
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
The price is $84 per night from Jun 2 to Jun 3
$84
per night
Jun 2 - Jun 3
Book a stay at this business-friendly hotel in Jackson. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (373 reviews)
"A nice, clean , quiet property. Very good buy"

Reviewed on Apr 29, 2024

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Holiday Inn Express & Suites Murphysboro - Carbondale, an IHG Hotel
Holiday Inn Express & Suites Murphysboro - Carbondale, an IHG Hotel
2.5 out of 5
120 MUDDY MONSTER ROAD, Murphysboro, IL
  • 2 hours drive from National Shrine of Our Lady of the Miraculous Medal
The price is $103 per night from May 27 to May 28
$103
per night
May 27 - May 28
Book a stay at this business-friendly hotel in Murphysboro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (315 reviews)
"It was nice"

Reviewed on May 10, 2024

Holiday Inn Express & Suites Murphysboro - Carbondale, an IHG Hotel
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
2.5 out of 5
2904 Old Orchard Rd, Jackson, MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
The price is $98 per night from Jun 2 to Jun 3
$98
per night
Jun 2 - Jun 3
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
8.2/10 Very Good! (637 reviews)
"Clean comfortable room"

Reviewed on May 12, 2024

Comfort Suites Jackson-Cape Girardeau
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
3 out of 5
225 Drury Lane, Jackson, MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
The price is $108 per night from May 26 to May 27
$108
per night
May 26 - May 27
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (955 reviews)
Great Hotel
"Good quality clean hotel. Our family stayed for a soccer tournament and would stay again."

Reviewed on May 15, 2024

Drury Inn & Suites Jackson MO
Town House Inn
Town House Inn
2.5 out of 5
517 E Jackson Blvd, Jackson, MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
The price is $82 per night from May 19 to May 20
$82
per night
May 19 - May 20
Stay at this motel in Jackson. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Litz Park and Lazy L Safari Park are located ...
8/10 Very Good! (290 reviews)
Soccer Family
"We were in town for a soccer tournament and was looking for a comfortable yet affordable weekend stay. Over all we were very satisified and will stay here again next year. Hotel was quit and clean. the full kitchen was a blessing to have for a family trip. easy access to ice and had coin oporated ..."

Reviewed on May 10, 2024

Town House Inn
Best Western Chester Hotel
Best Western Chester Hotel
2.5 out of 5
2150 State Street, Chester, IL
  • 35 min drive from National Shrine of Our Lady of the Miraculous Medal
The price is $87 per night from May 22 to May 23
$87
per night
May 22 - May 23
Book a stay at this business-friendly hotel in Chester. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the property condition ...
8.6/10 Excellent! (248 reviews)
"Very nice staff and clean room. I do wish there was more work out equipment."

Reviewed on May 10, 2024

Best Western Chester Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Perryville

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Perryville.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Perryville’s 123 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $60. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Perryville hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Perryville. No matter your reason for visiting Perryville, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Perryville hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Perryville for as low as $60.

How many hotels are there in Perryville?

With over 123 hotels in Perryville, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $60.

How to find cheap car rentals in Perryville?

Finding a cheap car rental deal in Perryville is as easy as scoring cheap hotels in Perryville. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Perryville now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Perryville right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.