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Hotels in Perryville

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Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

2.5 out of 5
2020 Jefferson St Perryville MO
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (566 reviews)
Room was great, front desk was professional but friendly. Breakfast was excellent. Spotless — both room and lobby.

Reviewed on Feb 24, 2026

Holiday Inn Express & Suites Perryville by IHG
Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville

2 out of 5
1119 Vincent Dr Perryville MO
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly motel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (964 reviews)
We booked here bc the pictures show a hot tub , there is no hot tub. It’s been bricked in. The pictures do not represent the property. There were people swimming and running in the halls that were not staying there. I walked out side and they were running to their car in their swimsuits and running ...

Reviewed on Mar 17, 2026

Super 8 by Wyndham Perryville
Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville

2 out of 5
1500 Liberty Street Perryville MO
  • 27 min walk from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Perryville Country Club and ...
6.8/10 (425 reviews)
furniture worn off, ok breakfast, but right off freeway so easy access

Reviewed on Mar 17, 2026

Days Inn by Wyndham Perryville
Quality Inn Perryville I-55

Quality Inn Perryville I-55

2.5 out of 5
1517 S. Perryville Blvd. Perryville MO
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
Stay at this hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Perryville Country Club and Saint Marys Lake are located ...
6.6/10 (128 reviews)
satisfactory

Reviewed on Mar 12, 2026

Quality Inn Perryville I-55
Urban Lofts

Urban Lofts

3 out of 5
102 N Jackson St Perryville MO
  • 5 min drive from National Shrine of Our Lady of the Miraculous Medal
Stay at this aparthotel in Perryville. Enjoy free WiFi, free parking, and dry cleaning or laundry services. Popular attractions Feltz Street Park and Perryville ...
9.2/10 Wonderful! (17 reviews)
Great place to stay!

Reviewed on Oct 21, 2024

Urban Lofts
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (725 reviews)
Hotel staff were friendly and helpful. Store and restaurants were a short drive away.

Reviewed on Mar 17, 2026

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane Jackson MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (1,005 reviews)
Good

Reviewed on Mar 13, 2026

Drury Inn & Suites Jackson MO
Microtel Inn & Suites by Wyndham Sainte Genevieve

Microtel Inn & Suites by Wyndham Sainte Genevieve

2.5 out of 5
21958 Hwy 32 Ste Genevieve MO
  • 49 min drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Ste Genevieve. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
8.8/10 Excellent! (627 reviews)
Thank you, Ste. Genevieve Microtel staff. We loved the stay. Comfortable beds with clean and spacious room. Good continental breakfast!

Reviewed on Mar 17, 2026

Microtel Inn & Suites by Wyndham Sainte Genevieve
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 out of 5
120 MUDDY MONSTER ROAD Murphysboro IL
  • 2 hours drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Murphysboro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (531 reviews)
Staff are super nice, helpful, and friendly! Breakfast was always great, good selection to choose from. Its clean and quiet, a perfect home away from home couldn't be happer!

Reviewed on Mar 15, 2026

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 out of 5
2904 Old Orchard Rd Jackson MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
8.2/10 Very Good! (752 reviews)
Hotel was ok, not terribly dirty, but not very clean. Chose for the jetted tub in the photo. Come to find out there was no jetted tub in the rooms, it was a regular very old tub that wasn’t quite clean looking, so definitely false advertising. I would absolutely not have chosen this hotel otherwise. ...

Reviewed on Mar 14, 2026

Comfort Suites Jackson-Cape Girardeau
Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG

2.5 out of 5
1301 N Market St Sparta IL
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Sparta. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (383 reviews)
Clean room super friendly staff

Reviewed on Mar 2, 2026

Holiday Inn Express Hotel & Suites Sparta by IHG
Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL

2.5 out of 5
2150 State Street Chester IL
  • 35 min drive from National Shrine of Our Lady of the Miraculous Medal
Book a stay at this business-friendly hotel in Chester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (367 reviews)
Welcoming to pets. Nice clean property. Comfy beds.

Reviewed on Mar 17, 2026

Baymont by Wyndham Chester IL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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