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Hotels in Perryville

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Tonight Apr 13 - Apr 14Next weekend Apr 18 - Apr 20

Choose from 139 Perryville Hotel Deals

Super 8 by Wyndham Perryville
Super 8 by Wyndham Perryville
2 out of 5
1119 Vincent Dr, Perryville, MO
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
The price is $81 per night from May 4 to May 5
$81
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly motel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (844 reviews)
"The staff was very friendly and the guy at the front desk was helpful with ever thing we asked about hotel was nice clean and quiet. Thus was my second time staying at this same hotel"

Reviewed on Mar 30, 2025

Super 8 by Wyndham Perryville
Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHG
2.5 out of 5
2020 Jefferson St, Perryville, MO
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
The price is $118 per night from Apr 20 to Apr 21
$118
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (455 reviews)
Sleep saver <3
"I was flooded out of going home after vacation. I was able to stay at the HIE through Hotels.com. The staff had me ready to go when I got there. They have amazing electric blinds to block the sunlight...I work nights."

Reviewed on Apr 10, 2025

Holiday Inn Express & Suites Perryville by IHG
Quality Inn Perryville I-55
Quality Inn Perryville I-55
2.5 out of 5
1517 S. Perryville Blvd., Perryville, MO
  • 28 min walk from National Shrine of Our Lady of the Miraculous Medal
The price is $92 per night from Apr 20 to Apr 21
$92
includes taxes & fees
Apr 20 - Apr 21
Stay at this hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Perryville Country Club and Saint Marys Lake are located ...
6.6/10 (98 reviews)
"Friendly staff. Close to gas station & food options."

Reviewed on Apr 4, 2025

Quality Inn Perryville I-55
Days Inn by Wyndham Perryville
Days Inn by Wyndham Perryville
2 out of 5
1500 Liberty Street, Perryville, MO
  • 27 min walk from National Shrine of Our Lady of the Miraculous Medal
The price is $90 per night from May 4 to May 5
$90
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Perryville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Perryville Country Club and ...
6.8/10 (396 reviews)
"Y"

Reviewed on Dec 30, 2024

Days Inn by Wyndham Perryville
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
2.5 out of 5
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
The price is $90 per night from Apr 15 to Apr 16
$90
includes taxes & fees
Apr 15 - Apr 16
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (529 reviews)
"Nice"

Reviewed on Apr 5, 2025

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
2.5 out of 5
120 MUDDY MONSTER ROAD, Murphysboro, IL
  • 2 hours drive from National Shrine of Our Lady of the Miraculous Medal
The price is $128 per night from Apr 27 to Apr 28
$128
includes taxes & fees
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Murphysboro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (421 reviews)
"Great property."

Reviewed on Apr 7, 2025

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
3 out of 5
225 Drury Lane, Jackson, MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
The price is $95 per night from Apr 17 to Apr 18
$95
includes taxes & fees
Apr 17 - Apr 18
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,001 reviews)
"Very accommodating and friendly staff! Helpful with stressful travelers😊 Great breakfast and evening kick back snacks and drinks!"

Reviewed on Apr 9, 2025

Drury Inn & Suites Jackson MO
Tru By Hilton Cape Girardeau
Tru By Hilton Cape Girardeau
2.5 out of 5
2520 Veterans Memorial Dr, Cape Girardeau, MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
The price is $115 per night from Apr 20 to Apr 21
$115
includes taxes & fees
Apr 20 - Apr 21
Stay at this hotel in Cape Girardeau. Enjoy free breakfast, free parking, and a fitness center. Popular attractions Cape Girardeau Conservation Nature Center ...
9.8/10 Exceptional! (7 reviews)
Very 21st century facility
"The manager wwnt above and beyond to make ua comfortable, the hotel had juat opened so everything was new and super clean, a very 21st century dwelling and very impressive The rooms however do not have cupboards and drawers for clothing and stuff, but overally it was nice."

Reviewed on Apr 12, 2025

Tru By Hilton Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
2.5 out of 5
2904 Old Orchard Rd, Jackson, MO
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
The price is $105 per night from Apr 15 to Apr 16
$105
includes taxes & fees
Apr 15 - Apr 16
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
8.2/10 Very Good! (697 reviews)
"V"

Reviewed on Mar 31, 2025

Comfort Suites Jackson-Cape Girardeau
Microtel Inn & Suites by Wyndham Sainte Genevieve
Microtel Inn & Suites by Wyndham Sainte Genevieve
2.5 out of 5
21958 Hwy 32, Ste Genevieve, MO
  • 49 min drive from National Shrine of Our Lady of the Miraculous Medal
The price is $100 per night from Apr 20 to Apr 21
$100
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Ste Genevieve. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (558 reviews)
"We skipped the breakfast - all cold and unappealing."

Reviewed on Apr 1, 2025

Microtel Inn & Suites by Wyndham Sainte Genevieve
Baymont by Wyndham Chester IL
Baymont by Wyndham Chester IL
2.5 out of 5
2150 State Street, Chester, IL
  • 35 min drive from National Shrine of Our Lady of the Miraculous Medal
The price is $103 per night from May 4 to May 5
$103
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Chester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...
8.6/10 Excellent! (293 reviews)
"The staff was wonderful and accomodating to my needs. And the place smelled AMAZING"

Reviewed on Mar 11, 2025

Baymont by Wyndham Chester IL
Holiday Inn Express Hotel & Suites Sparta by IHG
Holiday Inn Express Hotel & Suites Sparta by IHG
2.5 out of 5
1301 N Market St, Sparta, IL
  • 1 hour drive from National Shrine of Our Lady of the Miraculous Medal
The price is $124 per night from May 4 to May 5
$124
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Sparta. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (319 reviews)
"Great breakfast!"

Reviewed on Mar 18, 2025

Holiday Inn Express Hotel & Suites Sparta by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Perryville

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How many hotels are there in Perryville?

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