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Hotels in Cape Girardeau

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Choose from 153 Cape Girardeau Hotel Deals

The Riverview
The Riverview
3.5 out of 5
777 Main St, Cape Girardeau, MO
  • 18 min walk from Southeast Missouri State University
The price is $106 per night from Mar 23 to Mar 24
$106
includes taxes & fees
Mar 23 - Mar 24
Stay at this 3.5-star hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront ...
9.2/10 Wonderful! (181 reviews)
"Absolutely awesome staff. Property was very clean."

Reviewed on Mar 15, 2025

The Riverview
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
  • 8 min drive from Southeast Missouri State University
The price is $107 per night from Mar 30 to Mar 31
$107
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,002 reviews)
"lots of room and very clean. The rooms were great and the evening meal and breakfast were great."

Reviewed on Mar 18, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 out of 5
3253 William Street, Cape Girardeau, MO
  • 7 min drive from Southeast Missouri State University
The price is $116 per night from Mar 30 to Mar 31
$116
includes taxes & fees
Mar 30 - Mar 31
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (999 reviews)
"The staff members were all very friendly and helpful. My room could not have been better."

Reviewed on Mar 13, 2025

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
  • 8 min drive from Southeast Missouri State University
The price is $76 per night from Mar 24 to Mar 25
$76
includes taxes & fees
Mar 24 - Mar 25
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,007 reviews)
"Front desk was helpful and friendly. Beds comfortable and bathroom was clean."

Reviewed on Mar 17, 2025

Pear Tree Inn Cape Girardeau West
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
  • 8 min drive from Southeast Missouri State University
The price is $98 per night from Mar 25 to Mar 26
$98
includes taxes & fees
Mar 25 - Mar 26
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (742 reviews)
"I liked the kitchens and refrigerator."

Reviewed on Mar 16, 2025

Candlewood Suites Cape Girardeau by IHG
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
3 out of 5
400 Broadway St., Cape Girardeau, MO
  • 14 min walk from Southeast Missouri State University
The price is $152 per night from Mar 30 to Mar 31
$152
includes taxes & fees
Mar 30 - Mar 31
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
9.4/10 Exceptional! (403 reviews)
"Had a great visit to Cape. Lovely place to stay the night. Convenient to shoppin, food and fun!"

Reviewed on Mar 17, 2025

Courtyard by Marriott Cape Girardeau Downtown
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
  • 7 min drive from Southeast Missouri State University
The price is $76 per night from Mar 24 to Mar 25
$76
includes taxes & fees
Mar 24 - Mar 25
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,004 reviews)
"Run by the most wonderful bunch of little old ladies. This will be my new standard for hotels! Rooms very clean and hotel next to a really good Chinese buffett. Highly recommend."

Reviewed on Mar 17, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3 out of 5
3303 Campster Drive, Cape Girardeau, MO
  • 8 min drive from Southeast Missouri State University
The price is $107 per night from Mar 30 to Mar 31
$107
includes taxes & fees
Mar 30 - Mar 31
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (908 reviews)
"Staff was polite and very helpful and attentive. Will stay here the next time I’m passing through."

Reviewed on Mar 10, 2025

Drury Inn & Suites Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 out of 5
433 CAPE WEST CROSSINGS, Cape Girardeau, MO
  • 8 min drive from Southeast Missouri State University
The price is $105 per night from Mar 30 to Mar 31
$105
includes taxes & fees
Mar 30 - Mar 31
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fort D Historic Site and ...
9.2/10 Wonderful! (91 reviews)
"Easy on/off of hwy 55. The hotel room was clean and spacious. Good breakfast"

Reviewed on Mar 12, 2025

Fairfield Inn & Suites by Marriott Cape Girardeau
Quality Inn
Quality Inn
2.5 out of 5
2011 North Kingshighway, Cape Girardeau, MO
  • 9 min drive from Southeast Missouri State University
The price is $76 per night from Mar 23 to Mar 24
$76
includes taxes & fees
Mar 23 - Mar 24
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7/10 Good! (556 reviews)
"Clean very nice staff"

Reviewed on Mar 16, 2025

Quality Inn
Town House Inn Cape Giradreau
Town House Inn Cape Giradreau
2.5 out of 5
505 North Kingshighway Street, Cape Girardeau, MO
  • 28 min walk from Southeast Missouri State University
The price is $70 per night from Mar 23 to Mar 24
$70
includes taxes & fees
Mar 23 - Mar 24
Stay at this motel in Cape Girardeau. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Cape Splash Family Aquatic Center and Show ...
6/10 (173 reviews)
"This is a unique place, having a kitchen and clean and spacious rooms, very comfortable"

Reviewed on Feb 17, 2025

Town House Inn Cape Giradreau
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
2.5 out of 5
207 S Mt Auburn Rd, Cape Girardeau, MO
  • 7 min drive from Southeast Missouri State University
The price is $124 per night from Mar 30 to Mar 31
$124
includes taxes & fees
Mar 30 - Mar 31
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.6/10 Exceptional! (693 reviews)
"family trip to Cape G. This Hampton Inn is right off I-55 and also right off the roads to downtown Cape G. Plenty of places to eat and walk the dogs"

Reviewed on Mar 11, 2025

Hampton Inn Cape Girardeau I 55 East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Cape Girardeau

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Frequently Asked Questions About Cape Girardeau hotels

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How many hotels are there in Cape Girardeau?

With over 153 hotels in Cape Girardeau, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $70.

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Finding a cheap car rental deal in Cape Girardeau is as easy as scoring cheap hotels in Cape Girardeau. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.