Search for Cheap Deals onHotels in Cape Girardeau
Choose from 179 Cape Girardeau Hotel Deals
Drury Plaza Hotel Cape Girardeau Conference Center
"Property was very nice and clean, staff was great, breakfast all good. Only complaint is the noise, constant hall noise, constant noise above us like furniture moving all night, didnt get any sleep and the hotel i have been to that didn't have any form of fan noise, usually we can use a bathroom ..."
Reviewed on Jun 27, 2026
The Riverview
"It was clean and quiet. It wasn’t walkable though. It would have been nice if there was a way to enjoy the river like a balcony either from the room or from a restaurant or lounge."
Reviewed on Jun 27, 2026
Pear Tree Inn Cape Girardeau West
"The staff was extremely friendly. The charger in my room didn't work and the front desk worker allowed me to borrow one. She was extremely helpful. Breakfast was really good and my room was very clean. Bed was comfy and I had everything I needed. Would definitely stay again."
Reviewed on Jun 21, 2026
Drury Inn & Suites Cape Girardeau
"I was driving north to WI from South AL for work and needed a somewhat halfway stop, as a solo traveler I recommend this hotel. Easy to get to and felt safe at the hotel and the surrounding areas. I even walked over to Outback Steakhouse for dinner with no issues. Friendly and helpful front desk ..."
Reviewed on Jun 24, 2026
Candlewood Suites Cape Girardeau by IHG
"Great place to stay very nice staff."
Reviewed on Jun 26, 2026
Fairfield Inn & Suites by Marriott Cape Girardeau
"staff was very friendly and accommodating, would stay here again. rooms were comfortable and clean."
Reviewed on Jun 17, 2026
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
"Good place, and good breakfast."
Reviewed on Jun 26, 2026
Quality Inn Cape Girardeau North
"At 915 pm on a Friday night maintenance was using a hammer drill in concrete...just irritating and very loud!"
Reviewed on Jun 22, 2026
Courtyard by Marriott Cape Girardeau Downtown
"Excellent Hotel. Nicest Courtyard I’ve stayed at."
Reviewed on Jun 26, 2026
Tru By Hilton Cape Girardeau
"The entire experience was great. The only thing I missed was maybe some potoes added to the breakfast menu for non meat eaters and stubborn toddlers."
Reviewed on Jun 26, 2026
Hampton Inn Cape Girardeau I 55 East
"Fantastic stay at this hotel. Room was marvelous, and so was the breakfast."
Reviewed on Jun 15, 2026
Town House Inn Cape Giradreau
"We stayed here for the last two months due to our house had to be tore down. Excellent place for your pets if you have them. We had our 4 dogs so it worked the best. They were great and only a few things that we had to adjust for our liking. But for us if you have to use a place that is cheaper then ..."
Reviewed on Jun 25, 2026
Find cheap hotels in Cape Girardeau
You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Cape Girardeau hotel with Hotwire to complete your one-of-a-kind travel checklist.
For you, intrepid voyager, Hotwire has a large selection of the best hotels in Cape Girardeau.
Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Cape Girardeau’s 179 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $76. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Cape Girardeau hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Cape Girardeau. No matter your reason for visiting Cape Girardeau, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About Cape Girardeau hotels
Where can I find the best last-minute travel deals?
If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Cape Girardeau for as low as $76.
How many hotels are there in Cape Girardeau?
With over 179 hotels in Cape Girardeau, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $76.
How to find cheap car rentals in Cape Girardeau?
Finding a cheap car rental deal in Cape Girardeau is as easy as scoring cheap hotels in Cape Girardeau. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.
- Hotels near Century Casino & Hotel Cape Girardeau
- Hotels near Southeast Missouri State University
- Hotels near Riverfront Bridge Park
- Hotels near Hunter Valley Winery
- Hotels near Cape Splash Family Aquatic Center
- Hotels near Riverfront Park
- Hotels near eDen Spa & Salon
- Hotels near Cape Rock Park
- Hotels near Cape Girardeau Conservation Nature Center
- Hotels near Fort D Historic Site
- Hotels near Mississippi River
- Hotels near Shawnee National Forest
- Hotels near Ohio River Valley
- Hotels near Giant City State Park
- Hotels near Stone Creek Golf Club and Resort
- Hotels near StarView Vineyards
- Hotels near Trail of Tears State Park
- Hotels near Pomona Winery
- Hotels with Free Parking in Cape Girardeau
- Family Hotels in Cape Girardeau
- Hotels with a Pool in Cape Girardeau
- Casinos in Cape Girardeau
- Pet-friendly Hotels in Cape Girardeau
- Hotels with an Indoor Pool in Cape Girardeau
- Hotels with Hot Tubs in Cape Girardeau
- Hotel Wedding Venues in Cape Girardeau
- Apartment Hotel in Cape Girardeau
- Luxury Hotels in Cape Girardeau
- Resorts & Hotels with Spas in Cape Girardeau
- Hotels with smoking rooms in Cape Girardeau
- Winery Hotels in Cape Girardeau
- Adults Only Resorts & Hotels in Cape Girardeau
- Historic Hotels in Cape Girardeau
- Romantic Hotels in Cape Girardeau
- Carbondale Hotels
- Ozarks Hotels
- Sikeston Hotels
- Southern Illinois Hotels
- Jackson Hotels
- Perryville Hotels
- Murphysboro Hotels
- Makanda Hotels
- Anna Hotels
- Cobden Hotels
- Alto Pass Hotels
- Charleston Hotels
- Southeast Missouri Hotels
- Cairo Hotels
- Pomona Hotels
- Buncombe Hotels
- Marble Hill Hotels
- Jonesboro Hotels
- Dongola Hotels
- Central United States Hotels
