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Hotels in Cape Girardeau

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Choose from 146 Cape Girardeau Hotel Deals

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 out of 5
3253 William Street, Cape Girardeau, MO
  • 7 min drive from Southeast Missouri State University
The price is $112 per night from Jan 12 to Jan 13
$112
includes taxes & fees
Jan 12 - Jan 13, 2025
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (999 reviews)
Overnight stay
"I stayed over with 6 of my volleyball players for a tournament. Staff was friendly and helpful. Room was clean."

Reviewed on Dec 16, 2024

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3 out of 5
3303 Campster Drive, Cape Girardeau, MO
  • 8 min drive from Southeast Missouri State University
The price is $102 per night from Dec 28 to Dec 29
$102
includes taxes & fees
Dec 28 - Dec 29
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (841 reviews)
"The staff was super friendly. Really good!"

Reviewed on Dec 17, 2024

Drury Inn & Suites Cape Girardeau
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
  • 8 min drive from Southeast Missouri State University
The price is $72 per night from Dec 29 to Dec 30
$72
includes taxes & fees
Dec 29 - Dec 30
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,002 reviews)
"Always a great place to stay."

Reviewed on Nov 29, 2024

Pear Tree Inn Cape Girardeau West
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
  • 8 min drive from Southeast Missouri State University
The price is $112 per night from Dec 27 to Dec 28
$112
includes taxes & fees
Dec 27 - Dec 28
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,001 reviews)
Very kind staff
"Really good. My kiddo had a tonsillectomy done at the hospital there and the staff were very helpful. Got us extra yogurts so she could eat etc…. Thank you!"

Reviewed on Dec 17, 2024

Drury Plaza Hotel Cape Girardeau Conference Center
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
  • 7 min drive from Southeast Missouri State University
The price is $73 per night from Dec 24 to Dec 25
$73
includes taxes & fees
Dec 24 - Dec 25
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,000 reviews)
"clean room. barking dog"

Reviewed on Dec 9, 2024

Pear Tree Inn Cape Girardeau Near the Medical Center
Candlewood Suites Cape Girardeau, an IHG Hotel
Candlewood Suites Cape Girardeau, an IHG Hotel
2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
  • 7 min drive from Southeast Missouri State University
The price is $80 per night from Jan 5 to Jan 6
$80
includes taxes & fees
Jan 5 - Jan 6, 2025
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (708 reviews)
"Very spacious room with very comfortable bed."

Reviewed on Dec 20, 2024

Candlewood Suites Cape Girardeau, an IHG Hotel
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
3 out of 5
400 Broadway St., Cape Girardeau, MO
  • 14 min walk from Southeast Missouri State University
The price is $131 per night from Jan 1 to Jan 2
$131
includes taxes & fees
Jan 1 - Jan 2, 2025
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
9.4/10 Exceptional! (386 reviews)
"Loved the areas in the lobby for small groups to gather!"

Reviewed on Dec 15, 2024

Courtyard by Marriott Cape Girardeau Downtown
The Riverview
The Riverview
3.5 out of 5
777 Main St, Cape Girardeau, MO
  • 18 min walk from Southeast Missouri State University
The price is $102 per night from Dec 29 to Dec 30
$102
includes taxes & fees
Dec 29 - Dec 30
Stay at this 3.5-star hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront ...
9/10 Wonderful! (104 reviews)
"Very nice rooms and very big"

Reviewed on Dec 18, 2024

The Riverview
Quality Inn
Quality Inn
2.5 out of 5
2011 North Kingshighway, Cape Girardeau, MO
  • 9 min drive from Southeast Missouri State University
The price is $69 per night from Dec 24 to Dec 25
$69
includes taxes & fees
Dec 24 - Dec 25
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7/10 Good! (523 reviews)
"It was quite and clean"

Reviewed on Dec 18, 2024

Quality Inn
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
2.5 out of 5
207 S Mt Auburn Rd, Cape Girardeau, MO
  • 7 min drive from Southeast Missouri State University
The price is $124 per night from Dec 29 to Dec 30
$124
includes taxes & fees
Dec 29 - Dec 30
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.6/10 Exceptional! (683 reviews)
"Always a nice stay"

Reviewed on Dec 20, 2024

Hampton Inn Cape Girardeau I 55 East
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 out of 5
433 CAPE WEST CROSSINGS, Cape Girardeau, MO
  • 8 min drive from Southeast Missouri State University
The price is $100 per night from Dec 26 to Dec 27
$100
includes taxes & fees
Dec 26 - Dec 27
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fort D Historic Site and ...
9/10 Wonderful! (58 reviews)
"Very nice accommodations. Pleasant stay."

Reviewed on Dec 14, 2024

Fairfield Inn & Suites by Marriott Cape Girardeau
Town House Inn Cape Giradreau
Town House Inn Cape Giradreau
2.5 out of 5
505 North Kingshighway Street, Cape Girardeau, MO
  • 28 min walk from Southeast Missouri State University
The price is $64 per night from Jan 5 to Jan 6
$64
includes taxes & fees
Jan 5 - Jan 6, 2025
Stay at this motel in Cape Girardeau. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Cape Splash Family Aquatic Center and Show ...
6/10 (159 reviews)
Never again!
"It was a room to lay my head at night. Shower didn't work, ceiling paint was peeling and heavy smell of marijuana even though it was a no smoking room!"

Reviewed on Oct 27, 2024

Town House Inn Cape Giradreau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Cape Girardeau

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Frequently Asked Questions About Cape Girardeau hotels

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How many hotels are there in Cape Girardeau?

With over 146 hotels in Cape Girardeau, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $64.

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