Search for Cheap Deals onHotels in Cape Girardeau
Choose from 176 Cape Girardeau Hotel Deals
Drury Plaza Hotel Cape Girardeau Conference Center
"Very clean, helpful staff"
Reviewed on Jun 2, 2026
Candlewood Suites Cape Girardeau by IHG
"on check-in, staff did not tell us there was not breakfast provided. Room clean, well-organized. Had plenty of towels without having to ask for any extra. Had we known no kitchen we might have brought in food for breakfast. the bag of popcorn provided was tasty and welcome. Main negative was the ..."
Reviewed on Jun 6, 2026
The Riverview
"Out room wasn't ready (we arrived a little after 3, check-in time). We had to wait for the room to be cleaned. Other than that, it was clean and comfortable. I wish they had a better breakfast option and an earlier time."
Reviewed on Jun 1, 2026
Pear Tree Inn Cape Girardeau West
"Great hotel"
Reviewed on Jun 5, 2026
Fairfield Inn & Suites by Marriott Cape Girardeau
"The staff were excellent! Front desk and Breakfast staff were very friendly and attentive."
Reviewed on Jun 3, 2026
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
"The room was very spacious and great water pressure. Staff very kind to us, the breakfast was great as well"
Reviewed on Jun 5, 2026
Quality Inn Cape Girardeau North
"There isn’t much good about this property."
Reviewed on May 31, 2026
Drury Inn & Suites Cape Girardeau
"Wonderful stay. From beginning to the end."
Reviewed on Jun 6, 2026
Courtyard by Marriott Cape Girardeau Downtown
"Beautiful and comfortable room in a vibrant small downtown setting."
Reviewed on May 31, 2026
Tru By Hilton Cape Girardeau
"I would like to say that the staff are some of the nicest people I’ve encountered while traveling. Expedia messed up with the payment and it was a 2 hour process to undo it. But the hotel staff were amazing and did everything in their power to resolve the issue."
Reviewed on May 28, 2026
Hampton Inn Cape Girardeau I 55 East
"So convenient and friendly employees!"
Reviewed on Jun 3, 2026
Town House Inn Cape Giradreau
"Adequate"
Reviewed on Jun 3, 2026
Find cheap hotels in Cape Girardeau
You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Cape Girardeau hotel with Hotwire to complete your one-of-a-kind travel checklist.
For you, intrepid voyager, Hotwire has a large selection of the best hotels in Cape Girardeau.
Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Cape Girardeau’s 176 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $76. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Cape Girardeau hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Cape Girardeau. No matter your reason for visiting Cape Girardeau, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About Cape Girardeau hotels
Where can I find the best last-minute travel deals?
If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Cape Girardeau for as low as $76.
How many hotels are there in Cape Girardeau?
With over 176 hotels in Cape Girardeau, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $76.
How to find cheap car rentals in Cape Girardeau?
Finding a cheap car rental deal in Cape Girardeau is as easy as scoring cheap hotels in Cape Girardeau. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.
- Hotels near Century Casino & Hotel Cape Girardeau
- Hotels near Southeast Missouri State University
- Hotels near Riverfront Bridge Park
- Hotels near Hunter Valley Winery
- Hotels near Cape Splash Family Aquatic Center
- Hotels near Riverfront Park
- Hotels near eDen Spa & Salon
- Hotels near Cape Rock Park
- Hotels near Cape Girardeau Conservation Nature Center
- Hotels near Fort D Historic Site
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Giant City State Park
- Hotels near Ohio River Valley
- Hotels near Trail of Tears State Park
- Hotels near Stone Creek Golf Club and Resort
- Hotels near Pomona Winery
- Hotels with Free Parking in Cape Girardeau
- Family Hotels in Cape Girardeau
- Hotels with a Pool in Cape Girardeau
- Casinos in Cape Girardeau
- Pet-friendly Hotels in Cape Girardeau
- Hotels with an Indoor Pool in Cape Girardeau
- Hotels with Hot Tubs in Cape Girardeau
- Hotel Wedding Venues in Cape Girardeau
- Apartment Hotel in Cape Girardeau
- Luxury Hotels in Cape Girardeau
- Resorts & Hotels with Spas in Cape Girardeau
- Hotels with smoking rooms in Cape Girardeau
- Winery Hotels in Cape Girardeau
- Adults Only Resorts & Hotels in Cape Girardeau
- Historic Hotels in Cape Girardeau
- Romantic Hotels in Cape Girardeau
- Carbondale Hotels
- Sikeston Hotels
- Ozarks Hotels
- Southern Illinois Hotels
- Jackson Hotels
- Perryville Hotels
- Murphysboro Hotels
- Makanda Hotels
- Anna Hotels
- Cobden Hotels
- Alto Pass Hotels
- Cairo Hotels
- Charleston Hotels
- Southeast Missouri Hotels
- Buncombe Hotels
- Marble Hill Hotels
- Pomona Hotels
- Jonesboro Hotels
- Dongola Hotels
- Central United States Hotels
