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Hotels in Cape Girardeau

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Last Minute Hot Rate® Hotel Deals in Cape Girardeau

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Choose from 152 Cape Girardeau Hotel Deals

Quality Inn
Quality Inn
2.5 out of 5
2011 North Kingshighway, Cape Girardeau, MO
  • 9 min drive from Southeast Missouri State University
The price is $65 per night from Mar 31 to Apr 1
$65
per night
Mar 31 - Apr 1
Stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
6.8/10 (446 reviews)
"I would love to come back, very nice and welcoming place."

Reviewed on Jan 31, 2024

Quality Inn
Auburn Place Hotel And Suites
Auburn Place Hotel And Suites
2.5 out of 5
3265 William St, Cape Girardeau, MO
  • 7 min drive from Southeast Missouri State University
The price is $79 per night from Mar 31 to Apr 1
$79
per night
Mar 31 - Apr 1
Stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,004 reviews)
Ok but have had better experiences in past visits.
"We really like this hotel. Have stayed several times to visit family. Pool area is always clean. Breakfast is pretty good. Rooms are usually clean and comfortable. This time the room wasn't great. 2 of the queen beds was obviously very old and uncomfortable. The floors were dirty, the tub was very ..."

Reviewed on Mar 28, 2024

Auburn Place Hotel And Suites
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
  • 8 min drive from Southeast Missouri State University
The price is $112 per night from Apr 2 to Apr 3
$112
per night
Apr 2 - Apr 3
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
9.6/10 Exceptional! (1,007 reviews)
EXCELLENT
"Excellent hotel and staff. Highly recommend."

Reviewed on Mar 27, 2024

Drury Plaza Hotel Cape Girardeau Conference Center
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 out of 5
3253 William Street, Cape Girardeau, MO
  • 7 min drive from Southeast Missouri State University
The price is $117 per night from Apr 14 to Apr 15
$117
per night
Apr 14 - Apr 15
Stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,007 reviews)
"Excellent"

Reviewed on Mar 29, 2024

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
  • 8 min drive from Southeast Missouri State University
The price is $72 per night from Apr 3 to Apr 4
$72
per night
Apr 3 - Apr 4
Stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,009 reviews)
Cape Girardeau, MO
"Staff was very friendly and helpful. Bathroom could use a vanity update. The property looked good but the vanity made it look cheap."

Reviewed on Mar 16, 2024

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
  • 7 min drive from Southeast Missouri State University
The price is $67 per night from Apr 3 to Apr 4
$67
per night
Apr 3 - Apr 4
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,004 reviews)
"Very clean"

Reviewed on Mar 28, 2024

Pear Tree Inn Cape Girardeau Near the Medical Center
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3 out of 5
3303 Campster Drive, Cape Girardeau, MO
  • 8 min drive from Southeast Missouri State University
The price is $112 per night from Apr 2 to Apr 3
$112
per night
Apr 2 - Apr 3
Stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (753 reviews)
Will Definitely Return
"We were there with two grandchildren. It was a great size suite, very clean. The pool area and hot tub was very nice as well. The staff were all very friendly and helpful."

Reviewed on Mar 24, 2024

Drury Inn & Suites Cape Girardeau
Candlewood Suites Cape Girardeau, an IHG Hotel
Candlewood Suites Cape Girardeau, an IHG Hotel
2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
  • 7 min drive from Southeast Missouri State University
The price is $80 per night from Apr 1 to Apr 2
$80
per night
Apr 1 - Apr 2
Stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the clean rooms in our reviews. ...
8/10 Very Good! (594 reviews)
"Overall this was a good stay. We were on the side facing the interstate and we could hear the tragic. At first we thought, is the window open? But of course it wasn’t. Could even hear the interstate noise from the bathroom. I would stay again if I could be sure to get a room away from the interstate. ..."

Reviewed on Mar 25, 2024

Candlewood Suites Cape Girardeau, an IHG Hotel
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
3 out of 5
400 Broadway St., Cape Girardeau, MO
  • 14 min walk from Southeast Missouri State University
The price is $134 per night from Apr 14 to Apr 15
$134
per night
Apr 14 - Apr 15
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and breakfast. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (329 reviews)
Very modern hotel in an older building
"Stayed for a one night concert date night. The hotel was top notch from nice and clean. Very modern in an old building. 100 percent recommended"

Reviewed on Mar 8, 2024

Courtyard by Marriott Cape Girardeau Downtown
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
2.5 out of 5
207 S Mt Auburn Rd, Cape Girardeau, MO
  • 7 min drive from Southeast Missouri State University
The price is $114 per night from Apr 14 to Apr 15
$114
per night
Apr 14 - Apr 15
Stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (598 reviews)
Would Stay Again
"The hotel was very clean and comfortable. I got in about 9:30pm after a long day of driving and the check-in process was really smooth, and the staff were friendly. Breakfast was okay, I should've gone with the waffle, but I went with the eggs, sausage and biscuit. Pretty bland, but overall it was ..."

Reviewed on Mar 24, 2024

Hampton Inn Cape Girardeau I 55 East
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 out of 5
433 CAPE WEST CROSSINGS, Cape Girardeau, MO
  • 8 min drive from Southeast Missouri State University
The price is $110 per night from Apr 4 to Apr 5
$110
per night
Apr 4 - Apr 5
Stay at this hotel in Cape Girardeau. Enjoy breakfast, WiFi, and onsite parking. Popular attractions Fort D Historic Site and Cape Splash Family Aquatic Center ...
5.4/10 (3 reviews)
"We had a room on the first floor, it was very nice, well appointed. Very comfortable. The check in staff girl was very efficient and knowledgeable about the local area and places to eat. Breakfast was above and beyond what we expected. Thanks for a great stay!!"

Reviewed on Feb 19, 2024

Fairfield Inn & Suites by Marriott Cape Girardeau
Town House Inn Cape Giradreau
Town House Inn Cape Giradreau
2.5 out of 5
505 North Kingshighway Street, Cape Girardeau, MO
  • 28 min walk from Southeast Missouri State University
The price is $68 per night from Apr 9 to Apr 10
$68
per night
Apr 9 - Apr 10
Stay at this motel in Cape Girardeau. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Cape Splash Family Aquatic Center and Show ...
6/10 (134 reviews)
"Nothing like the one in jackson. I stayed at the townhouse inn in jackson mo then the one in cape girardeau. The one in jackson 10 stars the one in cape 2 stars so its woryh the 5 min drive"

Reviewed on Jul 29, 2023

Town House Inn Cape Giradreau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Cape Girardeau

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Cape Girardeau.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Cape Girardeau’s 152 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $65. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Cape Girardeau hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Cape Girardeau. No matter your reason for visiting Cape Girardeau, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Cape Girardeau hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Cape Girardeau for as low as $65.

How many hotels are there in Cape Girardeau?

With over 152 hotels in Cape Girardeau, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $65.

How to find cheap car rentals in Cape Girardeau?

Finding a cheap car rental deal in Cape Girardeau is as easy as scoring cheap hotels in Cape Girardeau. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Cape Girardeau now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Cape Girardeau right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.