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Hotels in Cape Girardeau

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Choose from 157 Cape Girardeau Hotel Deals

The Riverview
The Riverview
3.5 out of 5
777 Main St, Cape Girardeau, MO
  • 18 min walk from Southeast Missouri State University
The price is $109 per night from Apr 20 to Apr 21
$109
includes taxes & fees
Apr 20 - Apr 21
Stay at this 3.5-star hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront ...
9.2/10 Wonderful! (222 reviews)
"Very nice place"

Reviewed on Apr 8, 2025

The Riverview
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
  • 8 min drive from Southeast Missouri State University
The price is $107 per night from Apr 20 to Apr 21
$107
includes taxes & fees
Apr 20 - Apr 21
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,005 reviews)
"This was our first time at a Drury hotel so it came as quite a surprise that they provide supper as well as breakfast. Clean, well-kept motel; friendly, helpful staff."

Reviewed on Apr 11, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 out of 5
3253 William Street, Cape Girardeau, MO
  • 7 min drive from Southeast Missouri State University
The price is $116 per night from May 11 to May 12
$116
includes taxes & fees
May 11 - May 12
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,002 reviews)
"Will definitely stay there again!!"

Reviewed on Apr 9, 2025

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
  • 7 min drive from Southeast Missouri State University
The price is $76 per night from Apr 20 to Apr 21
$76
includes taxes & fees
Apr 20 - Apr 21
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,003 reviews)
"It was small room but was okay"

Reviewed on Mar 21, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3 out of 5
3303 Campster Drive, Cape Girardeau, MO
  • 8 min drive from Southeast Missouri State University
The price is $107 per night from Apr 18 to Apr 19
$107
includes taxes & fees
Apr 18 - Apr 19
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (916 reviews)
"5 Stars is not enough for all of the staff on duty April 4th, 2025. These folks are a SOLID 11! There was a genuine tornado approaching and they made sure all the lodgers were in safe spaces and appraised of what was going on. There was no hesitation of what to do, where to go and all was calm. Luckily, ..."

Reviewed on Apr 5, 2025

Drury Inn & Suites Cape Girardeau
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
  • 8 min drive from Southeast Missouri State University
The price is $81 per night from Apr 20 to Apr 21
$81
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,001 reviews)
"Nicr"

Reviewed on Apr 10, 2025

Pear Tree Inn Cape Girardeau West
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
  • 8 min drive from Southeast Missouri State University
The price is $98 per night from Apr 20 to Apr 21
$98
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (762 reviews)
"Very nice place to stay and friendly people"

Reviewed on Apr 6, 2025

Candlewood Suites Cape Girardeau by IHG
Quality Inn
Quality Inn
2.5 out of 5
2011 North Kingshighway, Cape Girardeau, MO
  • 9 min drive from Southeast Missouri State University
The price is $76 per night from Apr 15 to Apr 16
$76
includes taxes & fees
Apr 15 - Apr 16
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7/10 Good! (562 reviews)
"It was okay"

Reviewed on Apr 7, 2025

Quality Inn
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
3 out of 5
400 Broadway St., Cape Girardeau, MO
  • 14 min walk from Southeast Missouri State University
The price is $142 per night from May 11 to May 12
$142
includes taxes & fees
May 11 - May 12
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
9.4/10 Exceptional! (408 reviews)
"Amazing"

Reviewed on Apr 7, 2025

Courtyard by Marriott Cape Girardeau Downtown
Town House Inn Cape Giradreau
Town House Inn Cape Giradreau
2.5 out of 5
505 North Kingshighway Street, Cape Girardeau, MO
  • 28 min walk from Southeast Missouri State University
The price is $74 per night from Apr 15 to Apr 16
$74
includes taxes & fees
Apr 15 - Apr 16
Stay at this motel in Cape Girardeau. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Cape Splash Family Aquatic Center and Show ...
6/10 (178 reviews)
"NA"

Reviewed on Mar 26, 2025

Town House Inn Cape Giradreau
Tru By Hilton Cape Girardeau
Tru By Hilton Cape Girardeau
2.5 out of 5
2520 Veterans Memorial Dr, Cape Girardeau, MO
  • 12 min drive from Southeast Missouri State University
The price is $115 per night from Apr 20 to Apr 21
$115
includes taxes & fees
Apr 20 - Apr 21
Stay at this hotel in Cape Girardeau. Enjoy free breakfast, free parking, and a fitness center. Popular attractions Cape Girardeau Conservation Nature Center ...
9.8/10 Exceptional! (7 reviews)
Very 21st century facility
"The manager wwnt above and beyond to make ua comfortable, the hotel had juat opened so everything was new and super clean, a very 21st century dwelling and very impressive The rooms however do not have cupboards and drawers for clothing and stuff, but overally it was nice."

Reviewed on Apr 12, 2025

Tru By Hilton Cape Girardeau
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
2.5 out of 5
207 S Mt Auburn Rd, Cape Girardeau, MO
  • 7 min drive from Southeast Missouri State University
The price is $124 per night from Apr 20 to Apr 21
$124
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.6/10 Exceptional! (701 reviews)
"Great experience"

Reviewed on Apr 9, 2025

Hampton Inn Cape Girardeau I 55 East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Cape Girardeau

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How many hotels are there in Cape Girardeau?

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