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Hotels in Charleston

Choose from 86 Charleston Hotel Deals

Quality Inn Charleston - Sikeston
Quality Inn Charleston - Sikeston
2.5 out of 5
102 Drake St, I-57 Exit 10, Charleston, MO
  • 2 hours drive from Shawnee National Forest
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
6.8/10 (389 reviews)
"Our room was spacious and bed was comfortable, took a while to cool down but eventually did, enjoyed the in-room coffee."

Reviewed on Jun 22, 2025

Quality Inn Charleston - Sikeston
Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO
2 out of 5
310 S Story St, Charleston, MO
  • 2 hours drive from Shawnee National Forest
Stay at this motel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews.
6.6/10 (571 reviews)
"A great surprise in Owasso! Great price and excellent room. So impressed."

Reviewed on Jul 6, 2025

Super 8 by Wyndham Charleston/Sikeston East MO
Eagle Inn Charleston
Eagle Inn Charleston
2 out of 5
2811 East Marshall Street, Charleston, MO
  • 2 hours drive from Shawnee National Forest
Stay at this motel in Charleston. Enjoy free WiFi, free parking, and a health club.
6.8/10 (100 reviews)
"Furniture missing knobs. No chair!!??? No coffee!!?? No breakfast. Nice location. Nice staff!!"

Reviewed on May 21, 2025

Eagle Inn Charleston
The Riverview
The Riverview
2 out of 5
777 Main St, Cape Girardeau, MO
  • 2 hours drive from Shawnee National Forest
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront Park are ...
9.2/10 Wonderful! (332 reviews)
"Very nice place to stay. Close to restaurants and easy access."

Reviewed on Jul 11, 2025

The Riverview
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
  • 3 hours drive from Shawnee National Forest
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,008 reviews)
Great stay
"Awesome hotel. Beds are comfortable. Rooms are quiet. Breakfast was awesome."

Reviewed on Jul 13, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
  • 3 hours drive from Shawnee National Forest
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,009 reviews)
"We were travelling through and were pleasantly surprised at how well maintained the hotel was. Also breakfast was great with eggs and biscuits and gravy. Would definitely stay again."

Reviewed on Jul 8, 2025

Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
  • 3 hours drive from Shawnee National Forest
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,005 reviews)
"The staff here from check in to the morning breakfast were welcoming and friendly. Cost was reasonable. I loved seeing the dogs and that it is pet friendly. Everything was clean. The location was close to places to eat - we even walked to El Bracero for dinner. I would highly recommend"

Reviewed on Jul 11, 2025

Drury Inn & Suites Sikeston, MO
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 out of 5
3253 William Street, Cape Girardeau, MO
  • 3 hours drive from Shawnee National Forest
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,003 reviews)
"No Complaints"

Reviewed on Jul 11, 2025

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
  • 3 hours drive from Shawnee National Forest
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (1,009 reviews)
Nice One-Night Stay
"Stopped in in late June. One night stay. Rooms was fine. Bed was comfy and pillows were good. The 'continental' breakfast was severely lacking."

Reviewed on Jul 6, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
2.5 out of 5
207 S Mt Auburn Rd, Cape Girardeau, MO
  • 3 hours drive from Shawnee National Forest
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.6/10 Exceptional! (722 reviews)
"Jasmsine and Paige are excellent. Check- in was a snap."

Reviewed on Jun 28, 2025

Hampton Inn Cape Girardeau I 55 East
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
  • 3 hours drive from Shawnee National Forest
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (821 reviews)
"It was conveniently located. Its an older property needs more attention to cleaning all over premises."

Reviewed on Jul 7, 2025

Candlewood Suites Cape Girardeau by IHG
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
  • 3 hours drive from Shawnee National Forest
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,005 reviews)
Dogs on the loose in Cape
"quick check in. early check in was not an issue. room is clean and well equipped. TV was easy to operate. They do allow dogs one of which decided to pee on a bag of ours as we were outside our vehicle. dogs should always be on a leash. although the owner apologized she found it humorous."

Reviewed on Jul 12, 2025

Pear Tree Inn Cape Girardeau West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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