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Tonight Jun 7 - Jun 8Next weekend Jun 12 - Jun 14

Choose from 101 Charleston Hotel Deals

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St Charleston MO
  • 7 hours drive from Mississippi River
Stay at this motel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews.
6.6/10 (638 reviews)
"Clean rooms,"

Reviewed on May 31, 2026

Super 8 by Wyndham Charleston/Sikeston East MO
The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

2.5 out of 5
102 Drake St Charleston MO
  • 7 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
6.8/10 (414 reviews)
"It was not at all what I expected. The website showed a very good hotel. It was awful. I would not paid even $40/ night if I knew how awful it is. I felt bad for the ladies working on front desk."

Reviewed on Jun 7, 2026

The Riverstone Hotel Charleston-Sikeston
Eagle Inn Charleston

Eagle Inn Charleston

2 out of 5
2811 East Marshall Street Charleston MO
  • 7 hours drive from Mississippi River
Stay at this motel in Charleston. Enjoy free WiFi, free parking, and a health club.
6.6/10 (106 reviews)
"Great"

Reviewed on Apr 14, 2026

Eagle Inn Charleston
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
  • 6 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,005 reviews)
"Very clean, helpful staff"

Reviewed on Jun 2, 2026

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
  • 7 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,006 reviews)
"Clean rooms and was ready when we arrived. We did not use the pool but other guests were enjoying it. Breakfast and Kick back were both great meals."

Reviewed on Jun 4, 2026

Drury Inn & Suites Sikeston, MO
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
  • 6 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Century Casino & Hotel Cape ...
9.4/10 Exceptional! (591 reviews)
"Out room wasn't ready (we arrived a little after 3, check-in time). We had to wait for the room to be cleaned. Other than that, it was clean and comfortable. I wish they had a better breakfast option and an earlier time."

Reviewed on Jun 1, 2026

The Riverview
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 out of 5
485 S Mount Auburn Rd Cape Girardeau MO
  • 6 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (959 reviews)
"Rooms were dirty and they told us they don’t have any towels to give us."

Reviewed on Jun 7, 2026

Candlewood Suites Cape Girardeau by IHG
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
  • 7 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,004 reviews)
"The bathroom floor had hair all over it from a previous guest."

Reviewed on Jun 7, 2026

Days Inn and Suites by Wyndham Sikeston
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy Cape Girardeau MO
  • 6 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,006 reviews)
"Staff was nice. Beds comfy and room was clean. Continental breakfast with waffles."

Reviewed on Jun 6, 2026

Pear Tree Inn Cape Girardeau West
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
3253 William Street Cape Girardeau MO
  • 6 hours drive from Mississippi River
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,001 reviews)
"The room was very spacious and great water pressure. Staff very kind to us, the breakfast was great as well"

Reviewed on Jun 5, 2026

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
  • 7 hours drive from Mississippi River
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
9/10 Wonderful! (574 reviews)
"The doughnuts and fry potatoes for breakfast were delicious"

Reviewed on Jun 2, 2026

Hampton Inn Sikeston
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

3 out of 5
433 CAPE WEST CROSSINGS Cape Girardeau MO
  • 6 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fort D Historic Site and ...
9.4/10 Exceptional! (195 reviews)
"The staff were excellent! Front desk and Breakfast staff were very friendly and attentive."

Reviewed on Jun 3, 2026

Fairfield Inn & Suites by Marriott Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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