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Hotels in Charleston

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Tonight Feb 22 - Feb 23Next weekend Feb 28 - Mar 2

Choose from 87 Charleston Hotel Deals

Quality Inn Charleston - Sikeston
Quality Inn Charleston - Sikeston
2.5 out of 5
102 Drake St, I-57 Exit 10, Charleston, MO
  • 7 hours drive from Mississippi River
The price is $75 per night from Mar 15 to Mar 16
$75
includes taxes & fees
Mar 15 - Mar 16
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
6.6/10 (370 reviews)
"With my previous experience as a housekeeper at a hotel and knowing what areas to clean. I can say that the areas beyond the eye was not clean, the mirrors was dirty and they didn’t not offer complimentary breakfast or late check out."

Reviewed on Nov 25, 2024

Quality Inn Charleston - Sikeston
Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO
2 out of 5
310 S Story St, Charleston, MO
  • 7 hours drive from Mississippi River
The price is $69 per night from Feb 23 to Feb 24
$69
includes taxes & fees
Feb 23 - Feb 24
Stay at this motel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews.
6.6/10 (539 reviews)
"I was passing by and decided to take a break here. The bed was clean, had hot water and the heat was working. Took a quick 5 hour sleep and was back on the road."

Reviewed on Jan 12, 2025

Super 8 by Wyndham Charleston/Sikeston East MO
Eagle Inn Charleston
Eagle Inn Charleston
2 out of 5
2811 East Marshall Street, Charleston, MO
  • 7 hours drive from Mississippi River
The price is $71 per night from Feb 23 to Feb 24
$71
includes taxes & fees
Feb 23 - Feb 24
Stay at this motel in Charleston. Enjoy free WiFi, free parking, and a health club.
6.6/10 (95 reviews)
"Comfortable bed, easy access to room"

Reviewed on Oct 8, 2024

Eagle Inn Charleston
The Riverview
The Riverview
3.5 out of 5
777 Main St, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $109 per night from Feb 23 to Feb 24
$109
includes taxes & fees
Feb 23 - Feb 24
Stay at this 3.5-star hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront ...
9.2/10 Wonderful! (154 reviews)
"Check in was smooth and easy. Hotel was quiet nice and comfy . Big room with long windows is what I enjoyed the most. They also have restaurants but no pool sadly"

Reviewed on Feb 18, 2025

The Riverview
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $112 per night from Feb 26 to Feb 27
$112
includes taxes & fees
Feb 26 - Feb 27
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,006 reviews)
"The staff here are fabulous"

Reviewed on Feb 22, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 out of 5
3253 William Street, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $112 per night from Mar 2 to Mar 3
$112
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,000 reviews)
"Always a great stay!"

Reviewed on Feb 17, 2025

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3 out of 5
3303 Campster Drive, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $107 per night from Feb 26 to Feb 27
$107
includes taxes & fees
Feb 26 - Feb 27
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (892 reviews)
"Very nicely updated Comfortable beds Friendly and helpful staff"

Reviewed on Feb 17, 2025

Drury Inn & Suites Cape Girardeau
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $71 per night from Mar 2 to Mar 3
$71
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,003 reviews)
"Itso"

Reviewed on Feb 21, 2025

Pear Tree Inn Cape Girardeau West
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 out of 5
433 CAPE WEST CROSSINGS, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $105 per night from Mar 2 to Mar 3
$105
includes taxes & fees
Mar 2 - Mar 3
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fort D Historic Site and ...
9.2/10 Wonderful! (81 reviews)
Excellent!!
"Amazing place to stay. Very clean. Great breakfast and the staff was very accommodating and friendly! Will definitely book again when in the area!!"

Reviewed on Feb 17, 2025

Fairfield Inn & Suites by Marriott Cape Girardeau
Candlewood Suites Cape Girardeau, an IHG Hotel
Candlewood Suites Cape Girardeau, an IHG Hotel
2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $98 per night from Mar 16 to Mar 17
$98
includes taxes & fees
Mar 16 - Mar 17
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (734 reviews)
"Room was nice. Really liked the kitchen area it had. Staff was very nice and helpful. Would stay again."

Reviewed on Feb 20, 2025

Candlewood Suites Cape Girardeau, an IHG Hotel
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
3 out of 5
400 Broadway St., Cape Girardeau, MO
  • 6 hours drive from Mississippi River
The price is $142 per night from Mar 9 to Mar 10
$142
includes taxes & fees
Mar 9 - Mar 10
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
9.4/10 Exceptional! (397 reviews)
Perfect place to stay
"I love this hotel. It's clean, the staff is friendly, and the location is perfect."

Reviewed on Feb 16, 2025

Courtyard by Marriott Cape Girardeau Downtown
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
  • 7 hours drive from Mississippi River
The price is $73 per night from Feb 24 to Feb 25
$73
includes taxes & fees
Feb 24 - Feb 25
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,001 reviews)
Quiet and comfy
"This was a very nice place to stay. The property was older; however, it was newly renovated and super clean. Well, everything but the shower/tub combo. There was some kind of weird patch at the bottom of the tub, but it worked and the height of the shower head was great - a very tall person can actually ..."

Reviewed on Feb 19, 2025

Days Inn and Suites by Wyndham Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Charleston

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