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Hotels in Charleston

Check Last Minute Charleston Hotel Deals

Tonight Sep 28 - Sep 29Next weekend Oct 4 - Oct 6

Choose from 86 Charleston Hotel Deals

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO
2 out of 5
310 S Story St, Charleston, MO
  • 2 hours drive from Shawnee National Forest
The price is $67 per night from Oct 6 to Oct 7
$67
includes taxes & fees
Oct 6 - Oct 7
Stay at this motel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews.
6.6/10 (523 reviews)
"Comfortable"

Reviewed on Aug 17, 2024

Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Charleston - Sikeston
Quality Inn Charleston - Sikeston
2.5 out of 5
102 Drake St, I-57 Exit 10, Charleston, MO
  • 2 hours drive from Shawnee National Forest
The price is $68 per night from Oct 14 to Oct 15
$68
includes taxes & fees
Oct 14 - Oct 15
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
6.6/10 (348 reviews)
"It’s ok"

Reviewed on Aug 1, 2024

Quality Inn Charleston - Sikeston
Eagle Inn Charleston
Eagle Inn Charleston
2 out of 5
2811 East Marshall Street, Charleston, MO
  • 2 hours drive from Shawnee National Forest
The price is $77 per night from Sep 29 to Sep 30
$77
includes taxes & fees
Sep 29 - Sep 30
Stay at this motel in Charleston. Enjoy free WiFi, free parking, and a health club.
6.6/10 (94 reviews)
"Ok"

Reviewed on Jun 29, 2024

Eagle Inn Charleston
Auburn Place Hotel And Suites
Auburn Place Hotel And Suites
2.5 out of 5
3265 William St, Cape Girardeau, MO
  • 3 hours drive from Shawnee National Forest
The price is $89 per night from Sep 29 to Sep 30
$89
includes taxes & fees
Sep 29 - Sep 30
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
8.8/10 Excellent! (1,004 reviews)
"The wifi wasn't working when we arrived. After they reset the server, it was slow and spotty. The complementary breakfast was cold, otherwise not bad."

Reviewed on Sep 25, 2024

Auburn Place Hotel And Suites
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
  • 3 hours drive from Shawnee National Forest
The price is $77 per night from Oct 14 to Oct 15
$77
includes taxes & fees
Oct 14 - Oct 15
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,000 reviews)
"Clean, large room"

Reviewed on Sep 17, 2024

Days Inn and Suites by Wyndham Sikeston
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
  • 3 hours drive from Shawnee National Forest
The price is $71 per night from Oct 6 to Oct 7
$71
includes taxes & fees
Oct 6 - Oct 7
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,002 reviews)
"Nice older hotel. Beds are comfortable. Close to the hospital. Will stay here again if need to for family in hospital. Staff friendly and courteous. We had to book another night and they made it easy."

Reviewed on Sep 27, 2024

Pear Tree Inn Cape Girardeau Near the Medical Center
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
  • 3 hours drive from Shawnee National Forest
The price is $112 per night from Oct 20 to Oct 21
$112
includes taxes & fees
Oct 20 - Oct 21
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,001 reviews)
"On way to Memphis , perfect stop over . The Southerner restaurant was delicious and a nice selection of wine / bourbon"

Reviewed on Sep 21, 2024

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Sikeston, MO
  • 3 hours drive from Shawnee National Forest
The price is $112 per night from Oct 6 to Oct 7
$112
includes taxes & fees
Oct 6 - Oct 7
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,001 reviews)
"Great stay"

Reviewed on Sep 22, 2024

Drury Inn & Suites Sikeston, MO
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
  • 3 hours drive from Shawnee National Forest
The price is $72 per night from Oct 6 to Oct 7
$72
includes taxes & fees
Oct 6 - Oct 7
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,001 reviews)
"Very well-kept and excellent value for the money!"

Reviewed on Sep 25, 2024

Pear Tree Inn Cape Girardeau West
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 out of 5
3253 William Street, Cape Girardeau, MO
  • 3 hours drive from Shawnee National Forest
The price is $118 per night from Oct 13 to Oct 14
$118
includes taxes & fees
Oct 13 - Oct 14
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (999 reviews)
"Very friendly staff!"

Reviewed on Sep 21, 2024

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Candlewood Suites Cape Girardeau, an IHG Hotel
Candlewood Suites Cape Girardeau, an IHG Hotel
2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
  • 3 hours drive from Shawnee National Forest
The price is $89 per night from Oct 6 to Oct 7
$89
includes taxes & fees
Oct 6 - Oct 7
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (672 reviews)
"I’ve stayed here before and it is very nice. I was slightly disappointed to find toenail clippings and hair in the bathroom. Things happen, I’ve worked in housekeeping and I know housekeepers are human. The hair didn’t bother me as much as the toenail clippings, but still had a great stay."

Reviewed on Sep 26, 2024

Candlewood Suites Cape Girardeau, an IHG Hotel
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
  • 3 hours drive from Shawnee National Forest
The price is $93 per night from Oct 2 to Oct 3
$93
includes taxes & fees
Oct 2 - Oct 3
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,001 reviews)
Women’s Conference
"I recommend Pear Tree Inn, it is reasonably priced, the room was comfortable, the staff was friendly and helpful. It is located with easy access to the interstate."

Reviewed on Sep 22, 2024

Pear Tree Inn Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Charleston

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Charleston.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Charleston’s 86 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $67. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Charleston hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Charleston. No matter your reason for visiting Charleston, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Charleston hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Charleston for as low as $67.

How many hotels are there in Charleston?

With over 86 hotels in Charleston, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $67.

How to find cheap car rentals in Charleston?

Finding a cheap car rental deal in Charleston is as easy as scoring cheap hotels in Charleston. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Charleston now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Charleston right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.