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Choose from 102 Charleston Hotel Deals
Super 8 by Wyndham Charleston/Sikeston East MO
"For the price, the room was acceptable. There had been some attempts to update the rooms. There was no carpet in the room we were in. The bed was hard and on a squeaky platform. The air-conditioning was set to 78 when we arrived at 11pm so it was warm in the room as we were trying to go to sleep. ..."
Reviewed on Jul 22, 2026
The Riverstone Hotel Charleston-Sikeston
"Good stay. Would stay here again."
Reviewed on Jul 18, 2026
Eagle Inn Charleston
"Great"
Reviewed on Apr 14, 2026
Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview
"Such a great place in fact it was so nice I stayed a few more nights, the casino is amazing"
Reviewed on Jul 22, 2026
Drury Inn & Suites Sikeston, MO
"Some gluten free selections (muffins and/or bread) would be nice."
Reviewed on Jul 22, 2026
Pear Tree Inn Cape Girardeau West
"We enjoyed our stay. The staff was very kind. The facility is clean and the bed is comfortable. The pillows are small, but there are 5 on the bed, so it works out. If you have food allergies - such as dairy, the breakfast will not be available to you."
Reviewed on Jul 20, 2026
Drury Inn & Suites Cape Girardeau
Candlewood Suites Cape Girardeau by IHG
"Our bedside table lamp didn’t have plug to plug into and the microwave top kept falling when we open it."
Reviewed on Jul 22, 2026
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
"We definitely enjoyed our time. Thank you so much to the staff"
Reviewed on Jul 22, 2026
Best Western Plus Sikeston I-55
"Clean and comfortable room with good free breakfast"
Reviewed on Jul 18, 2026
Days Inn and Suites by Wyndham Sikeston
"Did not use the laundry service. The room was clean. The separate space in room 238 was amazing. The air conditioner was perfect. The staff was very kind and helpful. No complaints at all"
Reviewed on Jul 22, 2026
Find cheap hotels in Charleston
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Frequently Asked Questions About Charleston hotels
Where can I find the best last-minute travel deals?
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How many hotels are there in Charleston?
With over 102 hotels in Charleston, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $66.
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