Search Cheap Flights to
Charleston

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Cheap Flights to Charleston

Fall in love at first flight with your vacation to Charleston by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Charleston on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Charleston, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Charleston

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Charleston with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Charleston?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Charleston are in , but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Charleston?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find  to choose from for your flight to Charleston.

What airport is best to fly into Charleston?

When you’re planning your trip to Charleston, convenience is the name of the game. Luckily, Charleston Cairo Regional Airport is nearby so you can deplane and get going on checking off everything on your Charleston must-do list.

How much are flights to Charleston?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Charleston on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as , you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Charleston?

The trick to saving a stack of cash on your flight to Charleston? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as  right now, why wait?

Charleston Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$338

Last Minute Hotel Deals in Charleston

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St, Charleston, MO
Stay at this motel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews.
6.6/10 (592 reviews)
"Thank you!!!"

Reviewed on Sep 26, 2025

Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

2.5 out of 5
102 Drake St, I-57 Exit 10, Charleston, MO
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
6.8/10 (403 reviews)
"This property was clean but need more maintenance outside and need updating"

Reviewed on Sep 24, 2025

Quality Inn Charleston - Sikeston
Eagle Inn Charleston

Eagle Inn Charleston

2 out of 5
2811 East Marshall Street, Charleston, MO
Stay at this motel in Charleston. Enjoy free WiFi, free parking, and a health club.
6.6/10 (101 reviews)
"Furniture missing knobs. No chair!!??? No coffee!!?? No breakfast. Nice location. Nice staff!!"

Reviewed on May 21, 2025

Eagle Inn Charleston
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,023 reviews)
"Clean, friendly staff and business friendly"

Reviewed on Sep 28, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

2 out of 5
777 Main St, Cape Girardeau, MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau ...
9.2/10 Wonderful! (427 reviews)
"Beautiful hotel, but we had no view of the river from our room. Kind of disappointed."

Reviewed on Sep 29, 2025

The Riverview
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (1,009 reviews)
"Staff was friendly, room was clean, good location, good rate."

Reviewed on Sep 22, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,014 reviews)
"Everything was clean and looked newly renovated. Staff was friendly. Parking was convenient and the area seemed safe."

Reviewed on Sep 26, 2025

Pear Tree Inn Cape Girardeau West
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,000 reviews)
"Very nice and quiet"

Reviewed on Sep 30, 2025

Drury Inn & Suites Sikeston, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.