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Hotels in New Madrid

Choose from 56 New Madrid Hotel Deals

Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
  • 45 min drive from New Madrid Historical Museum
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (470 reviews)
very clean room

Reviewed on Jan 23, 2026

Hampton Inn Sikeston
Reelfoot Lake Inn

Reelfoot Lake Inn

2 out of 5
1520 State Route 21 East Tiptonville TN
  • 36 min drive from New Madrid Historical Museum
Stay at this motel in Tiptonville. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular ...
7/10 Good! (465 reviews)
Nice in clean room

Reviewed on Jan 19, 2026

Reelfoot Lake Inn
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

2.5 out of 5
1239 Commerce Drive Sikeston MO
  • 45 min drive from New Madrid Historical Museum
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
9.2/10 Wonderful! (50 reviews)
Very clean, staff pleasant and helpful

Reviewed on Jan 6, 2026

Fairfield Inn & Suites by Marriott Sikeston
New Orleans Inn Portageville

New Orleans Inn Portageville

2.5 out of 5
600 US-61 Portageville MO
  • 29 min drive from New Madrid Historical Museum
Stay at this motel in Portageville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (734 reviews)
Parking was good, staff was great

Reviewed on Jan 9, 2026

New Orleans Inn Portageville
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 out of 5
115 Hospitality Dr Sikeston MO
  • 45 min drive from New Madrid Historical Museum
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (447 reviews)
Stay was excellent

Reviewed on Dec 26, 2025

Holiday Inn Express & Suites Sikeston Southwest by IHG
Travel Inn

Travel Inn

2.5 out of 5
301 Route Ad Marston MO
  • 13 min drive from New Madrid Historical Museum
Stay at this hotel in Marston. Enjoy free breakfast, free WiFi, and free parking.
5.8/10 (117 reviews)
This motel is on a side road by open fields next to the expressway. The parking lot is large and well lit at night. It felt like a reasonably safe place. The desk clerk was friendly and helpful. The room was clean but a little worse for wear in some ways. The bed was comfortable and the HVAC unit ...

Reviewed on Nov 24, 2025

Travel Inn
TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston

3 out of 5
1239 Commerce Drive Sikeston MO
  • 45 min drive from New Madrid Historical Museum
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
9.2/10 Wonderful! (12 reviews)
Room was very nice and in very clean condition and hotel staff was very helpful and polite. The breakfast was very delicious and coffee served all day. The hotel smelled very nice and had a very welcoming feeling. Will definitely book with them again

Reviewed on Jan 18, 2026

TownePlace Suites by Marriott Sikeston
Super 8 By Wyndham Marston

Super 8 By Wyndham Marston

2 out of 5
501 S Outer Road Marston MO
  • 13 min drive from New Madrid Historical Museum
Stay at this hotel in Marston. Enjoy free breakfast, free WiFi, and free parking.
8/10 Very Good! (43 reviews)
Clean room, premises inviting, comfortable bed, good pillows.

Reviewed on Jan 9, 2026

Super 8 By Wyndham Marston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in New Madrid

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Frequently Asked Questions About New Madrid hotels

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How many hotels are there in New Madrid?

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