Search for Cheap Deals onHotels in New Madrid
Choose from 57 New Madrid Hotel Deals
Hampton Inn Sikeston
Was very clean & pet-friendly. Great place to stop on toad
Reviewed on Apr 4, 2026
Holiday Inn Express & Suites Sikeston Southwest by IHG
Fairfield Inn & Suites by Marriott Sikeston
Quick and friendly check where they offered us bottles of water. They added a lounge/bar that is very convenient. The outside lounge are is very nice as well. Room is clean with a comfortable bed and 2 different styles of pillows. Which is nice considering most hotels give you one kind of pillow ...
Reviewed on Apr 3, 2026
Reelfoot Lake Inn
The view of the lake is beautiful. It's right across the road. The manager and staff were very kind and set me up in the kind of room I requested. It had a microwave, refrigerator and coffee pot with the coffee. The bed was very comfortable and the air worked great. I would stay there again.
Reviewed on Mar 27, 2026
New Orleans Inn Portageville
The room was dusty, but other than that, it felt clean. There were 20 or so cats in the parking lot, and this is definitely a hotel people live in. There's too much to mention regarding that... Would I stay there again, probably not, but it was fine for me & my husband when we were too tired to keep ...
Reviewed on Apr 1, 2026
TownePlace Suites by Marriott Sikeston
Super 8 By Wyndham Marston
Great hotel for the price!!! Remodel very nice and modern.
Reviewed on Mar 30, 2026
Travel Inn
Quiet safe area.
Reviewed on Mar 23, 2026
Find cheap hotels in New Madrid
You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your New Madrid hotel with Hotwire to complete your one-of-a-kind travel checklist.
For you, intrepid voyager, Hotwire has a large selection of the best hotels in New Madrid.
Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of New Madrid’s 57 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $68. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great New Madrid hotel deals at the last minute.
While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in New Madrid. No matter your reason for visiting New Madrid, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.
Frequently Asked Questions About New Madrid hotels
Where can I find the best last-minute travel deals?
If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in New Madrid for as low as $68.
How many hotels are there in New Madrid?
With over 57 hotels in New Madrid, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $68.
How to find cheap car rentals in New Madrid?
Finding a cheap car rental deal in New Madrid is as easy as scoring cheap hotels in New Madrid. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.
- Hotels near New Madrid Historical Museum
- Hotels near River Ridge Winery
- Hotels near Hunter-Dawson State Historic Site
- Hotels near Mississippi River
- Hotels near Reelfoot Lake State Park
- Hotels near Central Park
- Hotels near Campbell's Point
- Hotels near Big Oak Tree State Park
- Hotels near Marston Community Center
- Sikeston Hotels
- Southeastern United States Hotels
- Union City Hotels
- Dexter Hotels
- Hayti Hotels
- Tiptonville Hotels
- Hornbeak Hotels
- Marston Hotels
- Charleston Hotels
- Southeast Missouri Hotels
- Portageville Hotels
- Western Tennessee Hotels
- Western Kentucky Hotels
- Samburg Hotels
- Malden Hotels
- The South Hotels
- Central United States Hotels
- East Prairie Hotels
- Bernie Hotels
- Great River Road Hotels
