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Hotels in New Madrid

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Tonight Apr 20 - Apr 21Next weekend Apr 25 - Apr 27

Choose from 48 New Madrid Hotel Deals

Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 out of 5
1240 Commerce Drive, Sikeston, MO
  • 45 min drive from New Madrid Historical Museum
The price is $143 per night from Apr 27 to Apr 28
$143
includes taxes & fees
Apr 27 - Apr 28
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (330 reviews)
"Staff was really nice"

Reviewed on Apr 10, 2025

Hampton Inn Sikeston
New Orleans Inn Portageville
New Orleans Inn Portageville
2.5 out of 5
600 US-61, Portageville, MO
  • 29 min drive from New Madrid Historical Museum
The price is $68 per night from Apr 27 to Apr 28
$68
includes taxes & fees
Apr 27 - Apr 28
Stay at this motel in Portageville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (649 reviews)
"The room itself was pretty nice even though a bit outdated it was worth the price paid. The outside of the building is kind of old and not very clean, could use some updates. Dining is very limited. We went to another town to have supper that was 12 miles away. The staff was very friendly!"

Reviewed on Apr 16, 2025

New Orleans Inn Portageville
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 out of 5
115 Hospitality Dr, Sikeston, MO
  • 45 min drive from New Madrid Historical Museum
The price is $139 per night from Apr 27 to Apr 28
$139
includes taxes & fees
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (401 reviews)
"Nothing"

Reviewed on Apr 11, 2025

Holiday Inn Express & Suites Sikeston Southwest by IHG
Super 8 By Wyndham Marston
Super 8 By Wyndham Marston
2 out of 5
501 S Outer Road, Marston, MO
  • 13 min drive from New Madrid Historical Museum
The price is $94 per night from Apr 21 to Apr 22
$94
includes taxes & fees
Apr 21 - Apr 22
Stay at this hotel in Marston.
7.8/10 Good! (17 reviews)
"Comfortable. No issues."

Reviewed on Apr 17, 2025

Super 8 By Wyndham Marston
TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott Sikeston
3 out of 5
1239 Commerce Drive, Sikeston, MO
  • 45 min drive from New Madrid Historical Museum
The price is $145 per night from Apr 27 to Apr 28
$145
includes taxes & fees
Apr 27 - Apr 28
Stay at this 3-star hotel in Sikeston. Popular attractions Central Park and Sikeston Depot Museum are located nearby.
TownePlace Suites by Marriott Sikeston
Travel Inn
Travel Inn
2.5 out of 5
301 Route Ad, Marston, MO
  • 13 min drive from New Madrid Historical Museum
The price is $77 per night from May 5 to May 6
$77
includes taxes & fees
May 5 - May 6
Stay at this hotel in Marston. Enjoy free breakfast, free WiFi, and free parking.
5.6/10 (99 reviews)
"Good"

Reviewed on Feb 25, 2025

Travel Inn
Fairfield by Marriott Inn & Suites Sikeston
Fairfield by Marriott Inn & Suites Sikeston
2.5 out of 5
1239 Commerce Drive, Sikeston, MO
  • 45 min drive from New Madrid Historical Museum
The price is $135 per night from Apr 27 to Apr 28
$135
includes taxes & fees
Apr 27 - Apr 28
Stay at this hotel in Sikeston. Popular attractions Central Park and Sikeston Depot Museum are located nearby.
Fairfield by Marriott Inn & Suites Sikeston
Reelfoot Lake Inn
Reelfoot Lake Inn
2 out of 5
1520 State Route 21 East, Tiptonville, TN
  • 36 min drive from New Madrid Historical Museum
Stay at this motel in Tiptonville. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular ...
7/10 Good! (436 reviews)
"The only thing upsetting was the pool was not in service."

Reviewed on Aug 3, 2024

Reelfoot Lake Inn
Boat Dock on Reelfoot Lake: Tiptonville Retreat
Boat Dock on Reelfoot Lake: Tiptonville Retreat
3 out of 5
Tiptonville
  • 24 min drive from New Madrid Historical Museum
Stay at this 3-star cottage in Tiptonville. Enjoy free parking, a marina, and balconies. Popular attractions Grassy Island and Horse Island are located ...
Boat Dock on Reelfoot Lake: Tiptonville Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in New Madrid

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How many hotels are there in New Madrid?

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