Search for Cheap Deals onHotels in New Madrid
Choose from 55 New Madrid Hotel Deals
Hampton Inn Sikeston
Very Clean room, friendly staff, breakfast in the morning. Will be staying again!
Reviewed on Feb 10, 2026
Reelfoot Lake Inn
Nice in clean room
Reviewed on Jan 19, 2026
New Orleans Inn Portageville
Clean room, Comfy bed and quiet surroundings made my quick stay comfortable. Reasonable price, close to restaurants, head shop, gas station and grocery.
Reviewed on Feb 9, 2026
Fairfield Inn & Suites by Marriott Sikeston
Clean rooms great staff
Reviewed on Feb 1, 2026
Holiday Inn Express & Suites Sikeston Southwest by IHG
Stay was excellent
Reviewed on Dec 26, 2025
Travel Inn
The room was great, TV was awesome. Staff was friendly.
Reviewed on Jan 25, 2026
Super 8 By Wyndham Marston
Room clean bed comfortable, breakfast simple but good.
Reviewed on Feb 11, 2026
TownePlace Suites by Marriott Sikeston
Room was very nice and in very clean condition and hotel staff was very helpful and polite. The breakfast was very delicious and coffee served all day. The hotel smelled very nice and had a very welcoming feeling. Will definitely book with them again
Reviewed on Jan 18, 2026
Find cheap hotels in New Madrid
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Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of New Madrid’s 55 hotels. Choose the one that best catches your trip’s tourist drift.
If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $68. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great New Madrid hotel deals at the last minute.
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Frequently Asked Questions About New Madrid hotels
Where can I find the best last-minute travel deals?
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How many hotels are there in New Madrid?
With over 55 hotels in New Madrid, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $68.
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