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New Madrid

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New Madrid Flights as Low as $169

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

KEY LIME AIR DBA DENVER AIR CONNECTION
KEY LIME AIR DBA DENVER AIR CONNECTION
KEY LIME AIR DBA DENVER AIR CONNECTION
KEY LIME AIR DBA DENVER AIR CONNECTION
KEY LIME AIR DBA DENVER AIR CONNECTION
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines

Cheap Flights to New Madrid

Fall in love at first flight with your vacation to New Madrid by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to New Madrid on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in New Madrid, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to New Madrid

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to New Madrid with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MAW airport.

What is the cheapest month to fly to New Madrid?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to New Madrid are in April, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to New Madrid?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to New Madrid.

What airport is best to fly into New Madrid?

When you’re planning your trip to New Madrid, convenience is the name of the game. Luckily, New Madrid Cairo Regional Airport is nearby so you can deplane and get going on checking off everything on your New Madrid must-do list.

How much are flights to New Madrid?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to New Madrid on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $169, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to New Madrid?

The trick to saving a stack of cash on your flight to New Madrid? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $169 right now, why wait?

New Madrid Flight Information
Destination airport
McKellar-Sipes Regional
Destination airport IATA code
MKL
Roundtrip price
$169

Last Minute Hotel Deals in New Madrid

Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 out of 5
1240 Commerce Drive, Sikeston, MO
The price is $124 per night from Apr 13 to Apr 14
$124
includes taxes & fees
Apr 13 - Apr 14
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (326 reviews)
Great family stay
"Clean, friendly staff, breakfast had good choices, quiet. Great for family stay."

Reviewed on Mar 23, 2025

Hampton Inn Sikeston
New Orleans Inn Portageville
New Orleans Inn Portageville
2.5 out of 5
600 US-61, Portageville, MO
The price is $68 per night from Apr 13 to Apr 14
$68
includes taxes & fees
Apr 13 - Apr 14
Stay at this motel in Portageville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (643 reviews)
"Favorite place to stay"

Reviewed on Mar 31, 2025

New Orleans Inn Portageville
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 out of 5
115 Hospitality Dr, Sikeston, MO
The price is $139 per night from Apr 20 to Apr 21
$139
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (399 reviews)
"Clean"

Reviewed on Mar 17, 2025

Holiday Inn Express & Suites Sikeston Southwest by IHG
Super 8 By Wyndham Marston
Super 8 By Wyndham Marston
2 out of 5
501 S Outer Road, Marston, MO
The price is $94 per night from Apr 9 to Apr 10
$94
includes taxes & fees
Apr 9 - Apr 10
Stay at this hotel in Marston.
7.8/10 Good! (16 reviews)
Decent for an overnight on the road
"Updated so looks nice and functional. Can see evidence of age in bathroom: door handle, plumbing to toilet, ceiling tiles. Overall decent with attractive updates. Service was good."

Reviewed on Mar 23, 2025

Super 8 By Wyndham Marston
Travel Inn
Travel Inn
2.5 out of 5
301 Route Ad, Marston, MO
The price is $77 per night from Apr 13 to Apr 14
$77
includes taxes & fees
Apr 13 - Apr 14
Stay at this hotel in Marston. Enjoy free breakfast, free WiFi, and free parking.
5.6/10 (99 reviews)
"Good"

Reviewed on Feb 25, 2025

Travel Inn
TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott Sikeston
3 out of 5
1239 Commerce Drive, Sikeston, MO
The price is $155 per night from Apr 13 to Apr 14
$155
includes taxes & fees
Apr 13 - Apr 14
Stay at this 3-star hotel in Sikeston. Popular attractions Central Park and Sikeston Depot Museum are located nearby.
TownePlace Suites by Marriott Sikeston
Reelfoot Lake Inn
Reelfoot Lake Inn
2 out of 5
1520 State Route 21 East, Tiptonville, TN
Stay at this motel in Tiptonville. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular ...
7/10 Good! (436 reviews)
"The only thing upsetting was the pool was not in service."

Reviewed on Aug 3, 2024

Reelfoot Lake Inn
Fairfield by Marriott Inn & Suites Sikeston
Fairfield by Marriott Inn & Suites Sikeston
2.5 out of 5
1239 Commerce Drive, Sikeston, MO
The price is $145 per night from Apr 13 to Apr 14
$145
includes taxes & fees
Apr 13 - Apr 14
Stay at this hotel in Sikeston. Popular attractions Central Park and Sikeston Depot Museum are located nearby.
Fairfield by Marriott Inn & Suites Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.