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New Madrid

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New Madrid Flights as Low as $503

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

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Cheap Flights to New Madrid

Fall in love at first flight with your vacation to New Madrid by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to New Madrid on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in New Madrid, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to New Madrid

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to New Madrid with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MAW airport.

What is the cheapest month to fly to New Madrid?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to New Madrid are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to New Madrid?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to New Madrid.

What airport is best to fly into New Madrid?

When you’re planning your trip to New Madrid, convenience is the name of the game. Luckily, New Madrid Cairo Regional Airport is nearby so you can deplane and get going on checking off everything on your New Madrid must-do list.

How much are flights to New Madrid?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to New Madrid on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $503, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to New Madrid?

The trick to saving a stack of cash on your flight to New Madrid? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $503 right now, why wait?

New Madrid Flight Information
Destination airport
Barkley Regional
Destination airport IATA code
PAH
Roundtrip price
$366

Last Minute Hotel Deals in New Madrid

Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive, Sikeston, MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (368 reviews)
"It was great"

Reviewed on Jul 27, 2025

Hampton Inn Sikeston
Fairfield by Marriott Inn & Suites Sikeston

Fairfield by Marriott Inn & Suites Sikeston

2.5 out of 5
1239 Commerce Drive, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
9.8/10 Exceptional! (16 reviews)
"Absolutely excellent. Brand new hotel. Spotless. Staff were friendly and welcoming."

Reviewed on Jul 26, 2025

Fairfield by Marriott Inn & Suites Sikeston
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 out of 5
115 Hospitality Dr, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (419 reviews)
"Thank you to the courteous staff. Great night's rest after a really long day of travel"

Reviewed on Jul 27, 2025

Holiday Inn Express & Suites Sikeston Southwest by IHG
New Orleans Inn Portageville

New Orleans Inn Portageville

2.5 out of 5
600 US-61, Portageville, MO
Stay at this motel in Portageville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (676 reviews)
"Was in town for a family reunion. Was able to book 3 rooms, quick and efficiently they were clean and comfortable."

Reviewed on Jul 29, 2025

New Orleans Inn Portageville
Super 8 By Wyndham Marston

Super 8 By Wyndham Marston

2 out of 5
501 S Outer Road, Marston, MO
Stay at this hotel in Marston. Enjoy free breakfast, free WiFi, and free parking.
7.8/10 Good! (24 reviews)
"Perfect for weary travelers. Clean; quiet; safe; friendly night desk lady."

Reviewed on May 9, 2025

Super 8 By Wyndham Marston
Reelfoot Lake Inn

Reelfoot Lake Inn

2 out of 5
1520 State Route 21 East, Tiptonville, TN
Stay at this motel in Tiptonville. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular ...
7/10 Good! (443 reviews)
"The property was fine. The a.c. Was working but it kinda hot for me as I can’t sleep good if I’m hot. But I am hot natured. But it cooled off over into the night. But overall it was good. The price was good and the inn keeper was very nice and helpful. Could have used more shampoo and soap."

Reviewed on Jul 10, 2025

Reelfoot Lake Inn
Travel Inn

Travel Inn

2.5 out of 5
301 Route Ad, Marston, MO
Stay at this hotel in Marston. Enjoy free breakfast, free WiFi, and free parking.
5.6/10 (106 reviews)
"The room was clean. The beds were comfortable."

Reviewed on May 25, 2025

Travel Inn
TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston

3 out of 5
1239 Commerce Drive, Sikeston, MO
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
8/10 Very Good! (4 reviews)
Good option for families!
"Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again."

Reviewed on Jul 27, 2025

TownePlace Suites by Marriott Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.