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New Madrid

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New Madrid Flights as Low as $376

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

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Cheap Flights to New Madrid

Fall in love at first flight with your vacation to New Madrid by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to New Madrid on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in New Madrid, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to New Madrid

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to New Madrid with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MAW airport.

What is the cheapest month to fly to New Madrid?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to New Madrid are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to New Madrid?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to New Madrid.

What airport is best to fly into New Madrid?

When you’re planning your trip to New Madrid, convenience is the name of the game. Luckily, New Madrid Cairo Regional Airport is nearby so you can deplane and get going on checking off everything on your New Madrid must-do list.

How much are flights to New Madrid?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to New Madrid on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $376, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to New Madrid?

The trick to saving a stack of cash on your flight to New Madrid? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $376 right now, why wait?

New Madrid Flight Information
Destination airport
Barkley Regional
Destination airport IATA code
PAH
Roundtrip price
$375

Last Minute Hotel Deals in New Madrid

Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
9/10 Wonderful! (573 reviews)
"The doughnuts and fry potatoes for breakfast were delicious"

Reviewed on Jun 2, 2026

Hampton Inn Sikeston
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

3 out of 5
1239 Commerce Drive Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
9.4/10 Exceptional! (84 reviews)
"Great stay, kind staff, very clean property."

Reviewed on May 30, 2026

Fairfield Inn & Suites by Marriott Sikeston
Reelfoot Lake Inn

Reelfoot Lake Inn

2 out of 5
1520 State Route 21 East Tiptonville TN
Stay at this motel in Tiptonville. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular ...
7.2/10 Good! (494 reviews)
"This place, although the pictures look nice is not what it was… it needs to be updated a lot. There are no amenities. Just the bar basics and you can get other places to go for around the same price with a lot more cleanliness and amenities included. We opted for a bed-and-breakfast instead up the ..."

Reviewed on Jun 1, 2026

Reelfoot Lake Inn
New Orleans Inn Portageville

New Orleans Inn Portageville

2.5 out of 5
600 US-61 Portageville MO
Stay at this motel in Portageville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (767 reviews)
"Great stay with Great people, very clean and welcoming"

Reviewed on Jun 1, 2026

New Orleans Inn Portageville
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 out of 5
115 Hospitality Dr Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (466 reviews)
"Only stayed one night, no complaints"

Reviewed on May 29, 2026

Holiday Inn Express & Suites Sikeston Southwest by IHG
Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O

2.5 out of 5
301 Route Ad Marston MO
Stay at this hotel in Marston. Enjoy free breakfast, free WiFi, and free parking.
6/10 (124 reviews)
"Worked for the price. Room was clean. Staff was friendly!"

Reviewed on May 13, 2026

Travel Inn Marston I-55 by Hotel O
Super 8 By Wyndham Marston

Super 8 By Wyndham Marston

2 out of 5
501 S Outer Road Marston MO
Stay at this hotel in Marston. Enjoy free breakfast, free WiFi, and free parking.
Super 8 By Wyndham Marston
TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston

3 out of 5
1239 Commerce Drive Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
9.2/10 Wonderful! (18 reviews)
"The breakfast staff was not good. The cream needed to be refilled. Oatmeal was not cooked. We had to wait for waffle machine to be fixed."

Reviewed on May 25, 2026

TownePlace Suites by Marriott Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.