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Hotels in East Prairie

Choose from 83 East Prairie Hotel Deals

Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive, Sikeston, MO
  • 47 min drive from Big Oak Tree State Park
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,004 reviews)
"Is an older building but not super old. The cleanliness and paint decor were top. This is the second time we have stayed and will do again."

Reviewed on Jul 21, 2025

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Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
  • 47 min drive from Big Oak Tree State Park
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,005 reviews)
"Enjoyed everything"

Reviewed on Jul 19, 2025

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Drury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
  • 47 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,001 reviews)
"Would have appreciated a way to charge our phone. We had our cord but nowhere to put it. Maybe a clock with the port for charging? The faucet leaked in the sink. Everything else was great."

Reviewed on Jul 15, 2025

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Pear Tree Inn Sikeston
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive, Sikeston, MO
  • 44 min drive from Big Oak Tree State Park
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (361 reviews)
"Not bad"

Reviewed on Jul 6, 2025

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Hampton Inn Sikeston
Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51

2.5 out of 5
1221 W Reelfoot Ave, Union City, TN
  • 41 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.8/10 (314 reviews)
It was ok
"The pool was filthy and the room floors was kinda gross . But if the house keepers did a better job it would have been a great stay. Crazy drunk guy at the pool .. pool was the reason for renting a room ."

Reviewed on Jul 7, 2025

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Hospitality House Union City I 69 / US 51
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO
  • 46 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,002 reviews)
Keep up the renovations
"This hotel looked like an old apartment building renovation into a hotel with much wrk in progress. Decent stay. Spacious. Very minimal breakfast offerings. The geese outside sure left messes everywhere but the greeting cat was a nice touch"

Reviewed on Jun 28, 2025

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Days Inn and Suites by Wyndham Sikeston
Quality Inn Union City US 51

Quality Inn Union City US 51

2.5 out of 5
2201 W Reelfoot Ave, Union City, TN
  • 43 min drive from Big Oak Tree State Park
Stay at this hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.2/10 Very Good! (456 reviews)
Would stay again
"Check in was quick. Staff was friendly. Bed and room needed some upgrades. There was no fan in the bathroom to ventilate when taking a shower. Breakfast in the morning was actually pretty good. Waffles, eggs, sausage, biscuits and gravy, cereal, fruit, etc… it wasn’t too bad and I wouldn’t mind staying ..."

Reviewed on Jun 28, 2025

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Quality Inn Union City US 51
Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG

2.5 out of 5
810 BREAM BOULEVARD, Union City, TN
  • 38 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (280 reviews)
"This hotel was directly across from the Discovery Park of America. Definitely recommend staying there!"

Reviewed on Jun 28, 2025

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Holiday Inn Express & Suites Union City by IHG
Fairfield by Marriott Inn & Suites Sikeston

Fairfield by Marriott Inn & Suites Sikeston

2.5 out of 5
1239 Commerce Drive, Sikeston, MO
  • 44 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
9.8/10 Exceptional! (14 reviews)
"The staff was amazing. Hotel was beautiful"

Reviewed on Jul 13, 2025

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Fairfield by Marriott Inn & Suites Sikeston
Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America

2.5 out of 5
1111 BLue Heron Lane, Union City, TN
  • 38 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Union City. Enjoy free parking, a 24-hour fitness center, and a 24-hour front desk. Popular attractions Discovery ...
9/10 Wonderful! (249 reviews)
Excellent CHOICE for Discovery
"I found the lobby area was clean and fresh feeling. Check-in was relatively simple, and staff was friendly and engaging. The room was clean, and I found the bed comfortable. There was virtually no noise, even in the morning. The breakfast was typical hot/cold breakfast items served at hotels, but ..."

Reviewed on Jul 10, 2025

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Sleep Inn at Discovery Park of America
Hampton Inn Union City

Hampton Inn Union City

2.5 out of 5
2121 W REELFOOT AVE, Union City, TN
  • 43 min drive from Big Oak Tree State Park
Stay at this hotel in Union City. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (142 reviews)
"Area quiet and peaceful"

Reviewed on Jul 19, 2025

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Hampton Inn Union City
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 out of 5
115 Hospitality Dr, Sikeston, MO
  • 44 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (416 reviews)
"Best free breakfast I’ve had in a long time."

Reviewed on Jul 20, 2025

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Holiday Inn Express & Suites Sikeston Southwest by IHG
See all 83 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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