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Hotels in East Prairie

Choose from 81 East Prairie Hotel Deals

Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
  • 47 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,003 reviews)
"Possibly the best overnight stay we have experienced in our travels."

Reviewed on May 8, 2025

Pear Tree Inn Sikeston
Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
  • 47 min drive from Big Oak Tree State Park
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,006 reviews)
"Our room was very nice and clean. We did not have any noise distractions. The breakfast was good and had several options. The front desk staff that checked us in was very welcoming. The only thing that was not the best was that we realized the morning we checked out that our door didn't lock from ..."

Reviewed on May 10, 2025

Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
  • 47 min drive from Big Oak Tree State Park
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,004 reviews)
great stay
"Staff was kind and rooms comfortable"

Reviewed on May 11, 2025

Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
  • 46 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,002 reviews)
"Nice and clean"

Reviewed on Apr 14, 2025

Days Inn and Suites by Wyndham Sikeston
Holiday Inn Express & Suites Union City by IHG
Holiday Inn Express & Suites Union City by IHG
2.5 out of 5
810 BREAM BOULEVARD, Union City, TN
  • 38 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (264 reviews)
5 plus stars
"Stay was amazing as always. Food was great. Hospitality was amazing. Great staff additudes even being short handed.."

Reviewed on Apr 27, 2025

Holiday Inn Express & Suites Union City by IHG
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 out of 5
1240 Commerce Drive, Sikeston, MO
  • 44 min drive from Big Oak Tree State Park
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (346 reviews)
"Perfect"

Reviewed on May 9, 2025

Hampton Inn Sikeston
Hospitality House Union City US 51
Hospitality House Union City US 51
2.5 out of 5
1221 W Reelfoot Ave, Union City, TN
  • 41 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.8/10 (294 reviews)
Nice place
"Room was clean. Property was clean and grassy ares kept up. Food places are close by. Good for one or two nights or extended stay for those working in the area temporarily."

Reviewed on Apr 24, 2025

Hospitality House Union City US 51
New Orleans Inn Portageville
New Orleans Inn Portageville
2.5 out of 5
600 US-61, Portageville, MO
  • 44 min drive from Big Oak Tree State Park
Stay at this motel in Portageville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (654 reviews)
"Clean"

Reviewed on Apr 27, 2025

New Orleans Inn Portageville
Quality Inn Union City US 51
Quality Inn Union City US 51
2.5 out of 5
2201 W Reelfoot Ave, Union City, TN
  • 43 min drive from Big Oak Tree State Park
Stay at this hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.4/10 Very Good! (433 reviews)
Quick Trip
"I had to make an overnight trip to Union City and this Quality Inn more then satisfied my needs."

Reviewed on Apr 29, 2025

Quality Inn Union City US 51
Country Yard Inn and Suite
Country Yard Inn and Suite
2 out of 5
110 South Interstate Drive, Sikeston, MO
  • 47 min drive from Big Oak Tree State Park
Stay at this motel in Sikeston. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions The Book Bug and Boot Heel Golf Club are located ...
7/10 Good! (90 reviews)
"Good but WiFi weak"

Reviewed on Apr 10, 2025

Country Yard Inn and Suite
Sleep Inn
Sleep Inn
2.5 out of 5
1111 BLue Heron Lane, Union City, TN
  • 38 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Union City. Enjoy free parking, a 24-hour fitness center, and a 24-hour front desk. Popular attractions Discovery ...
9/10 Wonderful! (233 reviews)
"We liked that it was out by it's self not congested traffic"

Reviewed on May 9, 2025

Sleep Inn
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 out of 5
115 Hospitality Dr, Sikeston, MO
  • 44 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (405 reviews)
"Fast, friendly front desk clerks. Amazed how clean the room was. This is the place to stay in the area!!"

Reviewed on May 7, 2025

Holiday Inn Express & Suites Sikeston Southwest by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in East Prairie

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