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Hotels in East Prairie

Choose from 76 East Prairie Hotel Deals

Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
  • 47 min drive from Big Oak Tree State Park
The price is $93 per night from Dec 6 to Dec 7
$93
includes taxes & fees
Dec 6 - Dec 7
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,000 reviews)
"Love how clean hotel was. Check in and check out staff was very professional and kind. I was always greeted when entering hotel."

Reviewed on Nov 23, 2024

Pear Tree Inn Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Sikeston, MO
  • 47 min drive from Big Oak Tree State Park
The price is $114 per night from Dec 1 to Dec 2
$114
includes taxes & fees
Dec 1 - Dec 2
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,000 reviews)
"It was a great place to stay."

Reviewed on Nov 25, 2024

Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
  • 46 min drive from Big Oak Tree State Park
The price is $72 per night from Dec 11 to Dec 12
$72
includes taxes & fees
Dec 11 - Dec 12
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,000 reviews)
"This was my first stay at this property. The rooms are very spacious with an extra sitting room. Got a great deal from expedia. Would definitely visit again."

Reviewed on Nov 17, 2024

Days Inn and Suites by Wyndham Sikeston
Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
  • 47 min drive from Big Oak Tree State Park
The price is $102 per night from Nov 28 to Nov 29
$102
includes taxes & fees
Nov 28 - Nov 29
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,000 reviews)
"The room is very clean and comfortable at a reasonable price. I will come back again when in the area!"

Reviewed on Nov 26, 2024

Best Western Plus Sikeston
New Orleans Inn Portageville
New Orleans Inn Portageville
2.5 out of 5
600 US-61, Portageville, MO
  • 44 min drive from Big Oak Tree State Park
The price is $68 per night from Dec 1 to Dec 2
$68
includes taxes & fees
Dec 1 - Dec 2
Stay at this motel in Portageville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (545 reviews)
"Very nice place to spend the night."

Reviewed on Nov 25, 2024

New Orleans Inn Portageville
Holiday Inn Express & Suites Union City, an IHG Hotel
Holiday Inn Express & Suites Union City, an IHG Hotel
2.5 out of 5
810 BREAM BOULEVARD, Union City, TN
  • 38 min drive from Big Oak Tree State Park
The price is $117 per night from Nov 29 to Nov 30
$117
includes taxes & fees
Nov 29 - Nov 30
Book a stay at this business-friendly hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (228 reviews)
"The plugs beside the bed didn't work, we were provided an extension cord for my CPAP machine, can't sleep without it. Come to find out two switches at the front door have to be on for the plugs to work. Learned that on the second day from the lovely lady that came up and explained it."

Reviewed on Nov 25, 2024

Holiday Inn Express & Suites Union City, an IHG Hotel
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 out of 5
100 Matthews Lane, Sikeston, MO
  • 47 min drive from Big Oak Tree State Park
The price is $71 per night from Nov 28 to Nov 29
$71
includes taxes & fees
Nov 28 - Nov 29
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (603 reviews)
10 out of 10
"Always a great place to stay, I won't stay anywhere else! Thank you."

Reviewed on Nov 25, 2024

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
2.5 out of 5
115 Hospitality Dr, Sikeston, MO
  • 45 min drive from Big Oak Tree State Park
The price is $121 per night from Dec 1 to Dec 2
$121
includes taxes & fees
Dec 1 - Dec 2
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (380 reviews)
"Our first stay in this particular Motel. Everything was great!"

Reviewed on Nov 11, 2024

Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
Hampton Inn Union City
Hampton Inn Union City
2.5 out of 5
2121 W REELFOOT AVE, Union City, TN
  • 43 min drive from Big Oak Tree State Park
The price is $121 per night from Dec 15 to Dec 16
$121
includes taxes & fees
Dec 15 - Dec 16
Stay at this hotel in Union City. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (101 reviews)
"Very nice!"

Reviewed on Nov 24, 2024

Hampton Inn Union City
Quality Inn Union City US 51
Quality Inn Union City US 51
2.5 out of 5
2201 W Reelfoot Ave, Union City, TN
  • 43 min drive from Big Oak Tree State Park
The price is $84 per night from Dec 15 to Dec 16
$84
includes taxes & fees
Dec 15 - Dec 16
Stay at this hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.4/10 Very Good! (406 reviews)
"Nice place to stay, nothing fancy but was a more modern hotel, will be staying again"

Reviewed on Nov 20, 2024

Quality Inn Union City US 51
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 out of 5
1240 Commerce Drive, Sikeston, MO
  • 44 min drive from Big Oak Tree State Park
The price is $141 per night from Dec 22 to Dec 23
$141
includes taxes & fees
Dec 22 - Dec 23
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (303 reviews)
"Great staff. Nice rooms. Good breakfast."

Reviewed on Nov 26, 2024

Hampton Inn Sikeston
Hospitality House Union City US 51
Hospitality House Union City US 51
2.5 out of 5
1221 W Reelfoot Ave, Union City, TN
  • 41 min drive from Big Oak Tree State Park
The price is $71 per night from Nov 28 to Nov 29
$71
includes taxes & fees
Nov 28 - Nov 29
Book a stay at this business-friendly hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.8/10 (256 reviews)
"Great staff"

Reviewed on Oct 18, 2024

Hospitality House Union City US 51
See all 76 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in East Prairie

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in East Prairie.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of East Prairie’s 76 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $68. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% East Prairie hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in East Prairie. No matter your reason for visiting East Prairie, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About East Prairie hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in East Prairie for as low as $68.

How many hotels are there in East Prairie?

With over 76 hotels in East Prairie, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $68.

How to find cheap car rentals in East Prairie?

Finding a cheap car rental deal in East Prairie is as easy as scoring cheap hotels in East Prairie. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to East Prairie now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to East Prairie right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.