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Last Minute Hot Rate® Hotel Deals in East Prairie

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Hot Rate® Hotel

3-star Hotel in Sikeston
3 out of 5

3-star Hotel

in Sikeston
12 miles from East Prairie
$83
per night
$104 total
incl. taxes & fees
3-star Hotel in Sikeston

Hot Rate® Hotel

3-star Hotel in Cape Girardeau - Jackson
3 out of 5

3-star Hotel

in Cape Girardeau - Jackson
41 miles from East Prairie
$92
per night
$114 total
incl. taxes & fees
3-star Hotel in Cape Girardeau - Jackson

Hot Rate® Hotel

3-star Hotel in Hayti
3 out of 5

3-star Hotel

in Hayti
43 miles from East Prairie
$109
per night
$135 total
incl. taxes & fees
3-star Hotel in Hayti
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Choose from 29 East Prairie Hotel Deals

Country Yard Inn and Suite
Country Yard Inn and Suite
2 out of 5
110 South Interstate Drive, Sikeston, MO
  • 7 hours drive from Mississippi River
The price is $58 per night from Apr 24 to Apr 25
$58
per night
Apr 24 - Apr 25
Stay at this motel in Sikeston. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions The Book Bug and Boot Heel Golf Club are located ...
7.2/10 Good! (26 reviews)
"The room smelled like cigarettes. The tv had no reception. The toilet was not solid when we sat on it. Etc"

Reviewed on Apr 9, 2024

Country Yard Inn and Suite
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
  • 7 hours drive from Mississippi River
The price is $63 per night from Apr 21 to Apr 22
$63
per night
Apr 21 - Apr 22
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7/10 Good! (1,001 reviews)
"Friendly staff, clean, very comfortable bed."

Reviewed on Apr 17, 2024

Days Inn and Suites by Wyndham Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Sikeston, MO
  • 7 hours drive from Mississippi River
The price is $108 per night from May 5 to May 6
$108
per night
May 5 - May 6
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.2/10 Wonderful! (1,000 reviews)
"We brought our 48lb pup with us to see the eclipse. Lots of grassy areas for my pup. Walked to the Mexican place next door and we sat outside to enjoy our dinner with our dog. Clean, patrons picked up after their dogs. No problems here."

Reviewed on Apr 15, 2024

Drury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
  • 7 hours drive from Mississippi River
The price is $90 per night from May 5 to May 6
$90
per night
May 5 - May 6
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool in our ...
9.2/10 Wonderful! (1,000 reviews)
"However, we were over charged on our room."

Reviewed on Apr 12, 2024

Pear Tree Inn Sikeston
Travel Inn & Suites
Travel Inn & Suites
2.5 out of 5
100 Matthews Lane, Sikeston, MO
  • 7 hours drive from Mississippi River
The price is $65 per night from Apr 21 to Apr 22
$65
per night
Apr 21 - Apr 22
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (511 reviews)
"Just traveling through. Checked in late and left early. Staff was accommodating and very nice."

Reviewed on Apr 13, 2024

Travel Inn & Suites
Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
  • 7 hours drive from Mississippi River
The price is $94 per night from Apr 21 to Apr 22
$94
per night
Apr 21 - Apr 22
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and WiFi. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions ...
8.4/10 Very Good! (1,002 reviews)
1night stay
"We enjoyed it with no issues"

Reviewed on Mar 28, 2024

Best Western Plus Sikeston
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
2.5 out of 5
115 Hospitality Dr, Sikeston, MO
  • 7 hours drive from Mississippi River
The price is $116 per night from Apr 28 to Apr 29
$116
per night
Apr 28 - Apr 29
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (340 reviews)
"Went for the eclipse and paid an outrageous price but otherwise a very nice hotel"

Reviewed on Apr 16, 2024

Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 out of 5
1240 Commerce Drive, Sikeston, MO
  • 7 hours drive from Mississippi River
The price is $110 per night from Apr 28 to Apr 29
$110
per night
Apr 28 - Apr 29
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (263 reviews)
"I enjoyed my stay. The beds are really comfortable. They have slide doors for the bathroom which I'm really not crazy about, but other than that everything was great. Front desk staff was really nice. Convenient right off the highway. I would definitely stay here again."

Reviewed on Mar 8, 2024

Hampton Inn Sikeston
Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55
2.5 out of 5
109 Matthews Ln, Sikeston, MO
  • 7 hours drive from Mississippi River
The price is $91 per night from Apr 28 to Apr 29
$91
per night
Apr 28 - Apr 29
Stay at this business-friendly hotel in Sikeston. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the clean rooms in our reviews. Popular ...
8.2/10 Very Good! (192 reviews)
"Great for overnights, staff friendly and attentive"

Reviewed on Apr 14, 2024

Comfort Inn & Suites Sikeston I-55
Red Roof Inn Sikeston - Marston
Red Roof Inn Sikeston - Marston
2 out of 5
501 SE Outer Rd, Marston, MO
  • 8 hours drive from Mississippi River
The price is $75 per night from Apr 21 to Apr 22
$75
per night
Apr 21 - Apr 22
Stay at this motel in Marston. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Marston Community Center is located nearby. Discover genuine ...
7/10 Good! (65 reviews)
"I liked it had an outdoor space to relax. I did not like the rod in my window holding it closed.(not sure how secure the window is?) I did not like that the upper lock on the door was broken and unable to secure the room."

Reviewed on Apr 18, 2024

Red Roof Inn Sikeston - Marston
Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner Area
2 out of 5
2609 E Malone Ave, Sikeston, MO
  • 7 hours drive from Mississippi River
The price is $58 per night from Apr 28 to Apr 29
$58
per night
Apr 28 - Apr 29
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions The Book Bug and Boot Heel Golf Club ...
6.4/10 (468 reviews)
"Price included breakfast."

Reviewed on Nov 30, 2023

Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Charleston MO
Super 8 by Wyndham Charleston MO
2 out of 5
310 S Story St, Charleston, MO
  • 7 hours drive from Mississippi River
The price is $68 per night from Apr 21 to Apr 22
$68
per night
Apr 21 - Apr 22
Stay at this motel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Discover genuine guest reviews for Super 8 by Wyndham Charleston MO along ...
6.6/10 (484 reviews)
"There was a bit of difficulty at check-in. The gentleman at the front desk was, with some effort, able to get me checked in without double-billing me for the room."

Reviewed on Mar 25, 2024

Super 8 by Wyndham Charleston MO
See all 29 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in East Prairie

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your East Prairie hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in East Prairie.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of East Prairie’s 29 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $58. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% East Prairie hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in East Prairie. No matter your reason for visiting East Prairie, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About East Prairie hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in East Prairie for as low as $58.

How many hotels are there in East Prairie?

With over 29 hotels in East Prairie, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $58.

How to find cheap car rentals in East Prairie?

Finding a cheap car rental deal in East Prairie is as easy as scoring cheap hotels in East Prairie. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to East Prairie now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to East Prairie right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.