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Choose from 86 East Prairie Hotel Deals
Drury Inn & Suites Sikeston, MO
The room was very nice and the bathroom was very clean. Everything was very nice and the breakfast was good. We were very pleased with everything. I recommend it highly.
Reviewed on Jan 2, 2026
Hampton Inn Sikeston
Room was very spacious, clean and well equipped Breakfast was good, staff was great and they had a great little mini store
Reviewed on Jan 5, 2026
Best Western Plus Sikeston
Nice and affordable option! Quiet place with clean facility throughout. Great people and good service.
Reviewed on Dec 29, 2025
Sleep Inn at Discovery Park of America
The rooms are big and the property is spotless!
Reviewed on Dec 27, 2025
Hospitality House Union City I 69 / US 51
Very friendly staff. Upgraded my room to accommodate my first floor request. Room was clean and very comfortable. I would definitely stay here again.
Reviewed on Dec 30, 2025
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Nice man and good hotel
Reviewed on Jan 1, 2026
Pear Tree Inn Sikeston
Great rooms. Spacious and food is great
Reviewed on Jan 6, 2026
Days Inn and Suites by Wyndham Sikeston
Staff was very nice. Room layout with two separate rooms was appreciated, especially at this price point. Good bed and bedding. Not super high end or careful about the rehab, and the breakfast was a carb fest, but overall we still felt it was a very good value
Reviewed on Dec 26, 2025
Hampton Inn Union City
Staff was great. Room was ready and clean.
Reviewed on Jan 5, 2026
Super 8 by Wyndham Sikeston/Miner Area
No bugs , A place I could feel at home again and
Reviewed on Jan 3, 2026
Quality Inn Union City US 51
The staff I interacted with were pleasant and helpful. Initially they had me in a 2nd floor room, but accommodated my asking for a first floor due to problems I was having with my knee and back. The bed was comfortable and overall the room was nice except for the bathroom shower, it had mold growing ...
Reviewed on Dec 10, 2025
Fairfield Inn & Suites by Marriott Sikeston
Staff promptly fixed a problem, room smelled very clean.
Reviewed on Jan 3, 2026
Find cheap hotels in East Prairie
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