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Hotels in East Prairie

Choose from 81 East Prairie Hotel Deals

Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
  • 47 min drive from Big Oak Tree State Park
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,002 reviews)
"Friendly"

Reviewed on Jun 23, 2025

Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
  • 47 min drive from Big Oak Tree State Park
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,003 reviews)
"Booked our stay online. Check-in was very easy and pleasant."

Reviewed on Jun 23, 2025

Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
  • 46 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,002 reviews)
"This property is updated, fresh paint in the halls and alot of work has gone into this location. The bed is comfortable and there are plenty of pillows (4)."

Reviewed on Jun 21, 2025

Days Inn and Suites by Wyndham Sikeston
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
  • 47 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,003 reviews)
Best Customer Service
"The best service. Most comfortable bed. Great breakfast. We will stay here on our next trip to Lamberts. Every employee we encountered spoke and asked how our day was going."

Reviewed on Jun 22, 2025

Pear Tree Inn Sikeston
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 out of 5
1240 Commerce Drive, Sikeston, MO
  • 44 min drive from Big Oak Tree State Park
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (357 reviews)
"In spite of being a smoke free faculty our room smelled like cigarette smoke very strongly."

Reviewed on Jun 20, 2025

Hampton Inn Sikeston
Holiday Inn Express & Suites Union City by IHG
Holiday Inn Express & Suites Union City by IHG
2.5 out of 5
810 BREAM BOULEVARD, Union City, TN
  • 38 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (276 reviews)
"Everyone was very nice, we left a pair of shorts on accident and they called within 1 hour of checking to let us know that we left something. They went above and beyond trying to accommodate us. My daughter got her hand slammed in the bathroom door and the front desk gave us the closet hospital ( ..."

Reviewed on May 27, 2025

Holiday Inn Express & Suites Union City by IHG
Quality Inn Union City US 51
Quality Inn Union City US 51
2.5 out of 5
2201 W Reelfoot Ave, Union City, TN
  • 43 min drive from Big Oak Tree State Park
Stay at this hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.4/10 Very Good! (449 reviews)
"Clean cool room"

Reviewed on Jun 23, 2025

Quality Inn Union City US 51
Country Yard Inn and Suite
Country Yard Inn and Suite
2 out of 5
110 South Interstate Drive, Sikeston, MO
  • 47 min drive from Big Oak Tree State Park
Stay at this motel in Sikeston. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Central Park and Sikeston Depot Museum are located ...
7/10 Good! (95 reviews)
"Good but WiFi weak"

Reviewed on Apr 10, 2025

Country Yard Inn and Suite
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 out of 5
115 Hospitality Dr, Sikeston, MO
  • 44 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (408 reviews)
"We pulled in late one evening. The ladies at the front desk were extremely nice and so helpful."

Reviewed on May 26, 2025

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sleep Inn at Discovery Park of America
Sleep Inn at Discovery Park of America
2.5 out of 5
1111 BLue Heron Lane, Union City, TN
  • 38 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Union City. Enjoy free parking, a 24-hour fitness center, and a 24-hour front desk. Popular attractions Discovery ...
9/10 Wonderful! (240 reviews)
"Very comfortable bed. Nice bathroom."

Reviewed on Jun 14, 2025

Sleep Inn at Discovery Park of America
Hampton Inn Union City
Hampton Inn Union City
2.5 out of 5
2121 W REELFOOT AVE, Union City, TN
  • 43 min drive from Big Oak Tree State Park
Stay at this hotel in Union City. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (133 reviews)
"Everything was clean and nice. Very spacious room. Bathroom was clean and spacious. The room had a comfy feeling. We liked that we could watch Netflix/disney on the tv. It also made me feel safe that the front desk let me know that my food delivery order was coming up. Nice breakfast layout. Breakfast ..."

Reviewed on Jun 14, 2025

Hampton Inn Union City
Hospitality House Union City I 69 / US 51
Hospitality House Union City I 69 / US 51
2.5 out of 5
1221 W Reelfoot Ave, Union City, TN
  • 41 min drive from Big Oak Tree State Park
Book a stay at this business-friendly hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.8/10 (304 reviews)
"Excellent experience from check-in to check-out. The room was spotless, well-stocked with essentials, and surprisingly quiet. Front desk staft were courteous and etficient. Great value and location-highly recommend for travelers seeking a comfortable and affordable stop."

Reviewed on Jun 11, 2025

Hospitality House Union City I 69 / US 51
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in East Prairie

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