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East Prairie

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East Prairie Flights as Low as $275

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Tue, Aug 5 - Wed, Aug 13
ATL
Hartsfield-Jackson Atlanta Intl.
CGI
Cape Girardeau Municipal
$275 Roundtrip, found 2 hours ago
$275
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Aug 5 from Hartsfield-Jackson Atlanta Intl. to Cape Girardeau Municipal, returning Wed, Aug 13, priced at $275 found 2 hours ago
American Airlines
Thu, Aug 7 - Wed, Aug 13
ATL
Hartsfield-Jackson Atlanta Intl.
CGI
Cape Girardeau Municipal
$285 Roundtrip, found 2 hours ago
$285
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Thu, Aug 7 from Hartsfield-Jackson Atlanta Intl. to Cape Girardeau Municipal, returning Wed, Aug 13, priced at $285 found 2 hours ago
American Airlines
Thu, Aug 7 - Wed, Aug 13
ATL
Hartsfield-Jackson Atlanta Intl.
CGI
Cape Girardeau Municipal
$311 Roundtrip, found 2 hours ago
$311
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Thu, Aug 7 from Hartsfield-Jackson Atlanta Intl. to Cape Girardeau Municipal, returning Wed, Aug 13, priced at $311 found 2 hours ago
American Airlines
Tue, Aug 5 - Wed, Aug 13
ATL
Hartsfield-Jackson Atlanta Intl.
CGI
Cape Girardeau Municipal
$320 Roundtrip, found 2 hours ago
$320
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Aug 5 from Hartsfield-Jackson Atlanta Intl. to Cape Girardeau Municipal, returning Wed, Aug 13, priced at $320 found 2 hours ago
American Airlines
Tue, Aug 5 - Wed, Aug 13
ATL
Hartsfield-Jackson Atlanta Intl.
CGI
Cape Girardeau Municipal
$322 Roundtrip, found 1 day ago
$322
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Aug 5 from Hartsfield-Jackson Atlanta Intl. to Cape Girardeau Municipal, returning Wed, Aug 13, priced at $322 found 1 day ago
American Airlines
Tue, Aug 5 - Thu, Aug 7
ATL
Hartsfield-Jackson Atlanta Intl.
CGI
Cape Girardeau Municipal
$323 Roundtrip, found 2 days ago
$323
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Aug 5 from Hartsfield-Jackson Atlanta Intl. to Cape Girardeau Municipal, returning Thu, Aug 7, priced at $323 found 2 days ago
American Airlines
Thu, Aug 7 - Wed, Aug 13
ATL
Hartsfield-Jackson Atlanta Intl.
CGI
Cape Girardeau Municipal
$330 Roundtrip, found 2 hours ago
$330
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Thu, Aug 7 from Hartsfield-Jackson Atlanta Intl. to Cape Girardeau Municipal, returning Wed, Aug 13, priced at $330 found 2 hours ago
United
Tue, Aug 5 - Wed, Aug 13
ATL
Hartsfield-Jackson Atlanta Intl.
CGI
Cape Girardeau Municipal
$332 Roundtrip, found 2 hours ago
$332
Roundtrip
found 2 hours ago
Select United flight, departing Tue, Aug 5 from Hartsfield-Jackson Atlanta Intl. to Cape Girardeau Municipal, returning Wed, Aug 13, priced at $332 found 2 hours ago
American Airlines
Tue, Aug 5 - Thu, Aug 7
ATL
Hartsfield-Jackson Atlanta Intl.
CGI
Cape Girardeau Municipal
$333 Roundtrip, found 2 days ago
$333
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Aug 5 from Hartsfield-Jackson Atlanta Intl. to Cape Girardeau Municipal, returning Thu, Aug 7, priced at $333 found 2 days ago
American Airlines
Wed, Aug 13 - Wed, Aug 13
ATL
Hartsfield-Jackson Atlanta Intl.
CGI
Cape Girardeau Municipal
$335 Roundtrip, found 5 days ago
$335
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Aug 13 from Hartsfield-Jackson Atlanta Intl. to Cape Girardeau Municipal, returning Wed, Aug 13, priced at $335 found 5 days ago
American Airlines
Wed, Aug 13 - Wed, Aug 20
ATL
Hartsfield-Jackson Atlanta Intl.
CGI
Cape Girardeau Municipal
$340 Roundtrip, found 5 days ago
$340
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Aug 13 from Hartsfield-Jackson Atlanta Intl. to Cape Girardeau Municipal, returning Wed, Aug 20, priced at $340 found 5 days ago
American Airlines
Tue, Aug 12 - Wed, Aug 13
ATL
Hartsfield-Jackson Atlanta Intl.
CGI
Cape Girardeau Municipal
$341 Roundtrip, found 5 days ago
$341
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Aug 12 from Hartsfield-Jackson Atlanta Intl. to Cape Girardeau Municipal, returning Wed, Aug 13, priced at $341 found 5 days ago
United
Tue, Aug 5 - Wed, Aug 13
ATL
Hartsfield-Jackson Atlanta Intl.
CGI
Cape Girardeau Municipal
$343 Roundtrip, found 2 hours ago
$343
Roundtrip
found 2 hours ago
Select United flight, departing Tue, Aug 5 from Hartsfield-Jackson Atlanta Intl. to Cape Girardeau Municipal, returning Wed, Aug 13, priced at $343 found 2 hours ago
American Airlines
Wed, Aug 6 - Wed, Aug 6
ATL
Hartsfield-Jackson Atlanta Intl.
CGI
Cape Girardeau Municipal
$343 Roundtrip, found 1 day ago
$343
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Aug 6 from Hartsfield-Jackson Atlanta Intl. to Cape Girardeau Municipal, returning Wed, Aug 6, priced at $343 found 1 day ago
American Airlines
Mon, Jul 28 - Mon, Aug 4
IAH
George Bush Intercontinental
CGI
Cape Girardeau Municipal
$350 Roundtrip, found 18 hours ago
$350
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Mon, Jul 28 from George Bush Intercontinental to Cape Girardeau Municipal, returning Mon, Aug 4, priced at $350 found 18 hours ago
American Airlines
Wed, Jul 23 - Wed, Jul 23
EWR
Newark Liberty Intl. Airport
CGI
Cape Girardeau Municipal
$388 Roundtrip, found 5 days ago
$388
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Jul 23 from Newark Liberty Intl. Airport to Cape Girardeau Municipal, returning Wed, Jul 23, priced at $388 found 5 days ago

Cheap Flights to East Prairie

Fall in love at first flight with your vacation to East Prairie by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to East Prairie on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in East Prairie, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to East Prairie

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to East Prairie with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CGI airport.

What is the cheapest month to fly to East Prairie?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to East Prairie are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to East Prairie?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to East Prairie.

What airport is best to fly into East Prairie?

When you’re planning your trip to East Prairie, convenience is the name of the game. Luckily, East Prairie Cairo Regional Airport is nearby so you can deplane and get going on checking off everything on your East Prairie must-do list.

How much are flights to East Prairie?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to East Prairie on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $275, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to East Prairie?

The trick to saving a stack of cash on your flight to East Prairie? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $275 right now, why wait?

East Prairie Flight Information
Destination airport
Cape Girardeau Municipal
Destination airport IATA code
CGI
Roundtrip price
$275

Last Minute Hotel Deals in East Prairie

Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,003 reviews)
"Didn’t have to think about anything. It was all right."

Reviewed on Jul 3, 2025

Get rates
Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,004 reviews)
"This is a great place to stay! Very clean, comfortable beds, free breakfast and supper. The people were very nice and I can’t recommend it highly enough!"

Reviewed on Jul 6, 2025

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Drury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,003 reviews)
"Very clean room and pool and good breakfast!"

Reviewed on Jun 30, 2025

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Pear Tree Inn Sikeston
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 out of 5
1240 Commerce Drive, Sikeston, MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (361 reviews)
"Not bad"

Reviewed on Jul 6, 2025

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Hampton Inn Sikeston
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,001 reviews)
Keep up the renovations
"This hotel looked like an old apartment building renovation into a hotel with much wrk in progress. Decent stay. Spacious. Very minimal breakfast offerings. The geese outside sure left messes everywhere but the greeting cat was a nice touch"

Reviewed on Jun 28, 2025

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Days Inn and Suites by Wyndham Sikeston
Fairfield by Marriott Inn & Suites Sikeston
Fairfield by Marriott Inn & Suites Sikeston
2.5 out of 5
1239 Commerce Drive, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
9.8/10 Exceptional! (10 reviews)
"Clean and comfortable"

Reviewed on Jun 25, 2025

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Fairfield by Marriott Inn & Suites Sikeston
Sleep Inn at Discovery Park of America
Sleep Inn at Discovery Park of America
2.5 out of 5
1111 BLue Heron Lane, Union City, TN
Book a stay at this business-friendly hotel in Union City. Enjoy free parking, a 24-hour fitness center, and a 24-hour front desk. Popular attractions Discovery ...
9/10 Wonderful! (245 reviews)
"The Sleep Inn was very nice and more than I expected. Quiet, clean, friendly staff, and close to area businesses such as restaurants. Sam and Linda at the front desk were super professional and knowledgeable in all areas. Will be back."

Reviewed on Jun 27, 2025

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Sleep Inn at Discovery Park of America
Quality Inn Union City US 51
Quality Inn Union City US 51
2.5 out of 5
2201 W Reelfoot Ave, Union City, TN
Stay at this hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.4/10 Very Good! (452 reviews)
Would stay again
"Check in was quick. Staff was friendly. Bed and room needed some upgrades. There was no fan in the bathroom to ventilate when taking a shower. Breakfast in the morning was actually pretty good. Waffles, eggs, sausage, biscuits and gravy, cereal, fruit, etc… it wasn’t too bad and I wouldn’t mind staying ..."

Reviewed on Jun 28, 2025

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Quality Inn Union City US 51
See all 81 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.