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East Prairie

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East Prairie Flights as Low as $518

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

United
Thu, Jul 9 - Tue, Jul 14
BWI
Baltimore Washington Intl. Thurgood Marshall
CGI
Cape Girardeau Municipal
$518 Roundtrip, found 15 hours ago
$518
Roundtrip
found 15 hours ago
Select United flight, departing Thu, Jul 9 from Baltimore Washington Intl. Thurgood Marshall to Cape Girardeau Municipal, returning Tue, Jul 14, priced at $518 found 15 hours ago
American Airlines
Sat, Jul 11 - Tue, Jul 14
BWI
Baltimore Washington Intl. Thurgood Marshall
CGI
Cape Girardeau Municipal
$528 Roundtrip, found 12 hours ago
$528
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Jul 11 from Baltimore Washington Intl. Thurgood Marshall to Cape Girardeau Municipal, returning Tue, Jul 14, priced at $528 found 12 hours ago
United
Thu, Jul 9 - Fri, Jul 17
BWI
Baltimore Washington Intl. Thurgood Marshall
CGI
Cape Girardeau Municipal
$528 Roundtrip, found 3 hours ago
$528
Roundtrip
found 3 hours ago
Select United flight, departing Thu, Jul 9 from Baltimore Washington Intl. Thurgood Marshall to Cape Girardeau Municipal, returning Fri, Jul 17, priced at $528 found 3 hours ago
United
Sat, Jul 11 - Tue, Jul 14
BWI
Baltimore Washington Intl. Thurgood Marshall
CGI
Cape Girardeau Municipal
$548 Roundtrip, found 12 hours ago
$548
Roundtrip
found 12 hours ago
Select United flight, departing Sat, Jul 11 from Baltimore Washington Intl. Thurgood Marshall to Cape Girardeau Municipal, returning Tue, Jul 14, priced at $548 found 12 hours ago
American Airlines
Sat, Jul 11 - Tue, Jul 14
BWI
Baltimore Washington Intl. Thurgood Marshall
CGI
Cape Girardeau Municipal
$558 Roundtrip, found 12 hours ago
$558
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Jul 11 from Baltimore Washington Intl. Thurgood Marshall to Cape Girardeau Municipal, returning Tue, Jul 14, priced at $558 found 12 hours ago
United
Tue, Jul 14 - Sat, Jul 18
TPA
Tampa Intl.
CGI
Cape Girardeau Municipal
$570 Roundtrip, found 4 days ago
$570
Roundtrip
found 4 days ago
Select United flight, departing Tue, Jul 14 from Tampa Intl. to Cape Girardeau Municipal, returning Sat, Jul 18, priced at $570 found 4 days ago
United
Sun, Jul 12 - Mon, Jul 13
BWI
Baltimore Washington Intl. Thurgood Marshall
CGI
Cape Girardeau Municipal
$578 Roundtrip, found 3 hours ago
$578
Roundtrip
found 3 hours ago
Select United flight, departing Sun, Jul 12 from Baltimore Washington Intl. Thurgood Marshall to Cape Girardeau Municipal, returning Mon, Jul 13, priced at $578 found 3 hours ago
American Airlines
Sun, Jul 12 - Wed, Jul 15
BWI
Baltimore Washington Intl. Thurgood Marshall
CGI
Cape Girardeau Municipal
$588 Roundtrip, found 4 days ago
$588
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sun, Jul 12 from Baltimore Washington Intl. Thurgood Marshall to Cape Girardeau Municipal, returning Wed, Jul 15, priced at $588 found 4 days ago
United
Tue, Jul 14 - Sat, Jul 18
TPA
Tampa Intl.
CGI
Cape Girardeau Municipal
$590 Roundtrip, found 6 days ago
$590
Roundtrip
found 6 days ago
Select United flight, departing Tue, Jul 14 from Tampa Intl. to Cape Girardeau Municipal, returning Sat, Jul 18, priced at $590 found 6 days ago
United
Sat, Jul 11 - Tue, Jul 14
BWI
Baltimore Washington Intl. Thurgood Marshall
CGI
Cape Girardeau Municipal
$592 Roundtrip, found 3 days ago
$592
Roundtrip
found 3 days ago
Select United flight, departing Sat, Jul 11 from Baltimore Washington Intl. Thurgood Marshall to Cape Girardeau Municipal, returning Tue, Jul 14, priced at $592 found 3 days ago
American Airlines
Thu, Jul 9 - Fri, Jul 17
BWI
Baltimore Washington Intl. Thurgood Marshall
CGI
Cape Girardeau Municipal
$598 Roundtrip, found 3 hours ago
$598
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Thu, Jul 9 from Baltimore Washington Intl. Thurgood Marshall to Cape Girardeau Municipal, returning Fri, Jul 17, priced at $598 found 3 hours ago
American Airlines
Sat, Jul 11 - Sat, Jul 18
TPA
Tampa Intl.
CGI
Cape Girardeau Municipal
$609 Roundtrip, found 14 hours ago
$609
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Sat, Jul 11 from Tampa Intl. to Cape Girardeau Municipal, returning Sat, Jul 18, priced at $609 found 14 hours ago
American Airlines
Tue, Jul 14 - Sat, Jul 18
TPA
Tampa Intl.
CGI
Cape Girardeau Municipal
$612 Roundtrip, found 7 hours ago
$612
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Tue, Jul 14 from Tampa Intl. to Cape Girardeau Municipal, returning Sat, Jul 18, priced at $612 found 7 hours ago
American Airlines
Sat, Jul 11 - Sat, Jul 18
TPA
Tampa Intl.
CGI
Cape Girardeau Municipal
$614 Roundtrip, found 14 hours ago
$614
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Sat, Jul 11 from Tampa Intl. to Cape Girardeau Municipal, returning Sat, Jul 18, priced at $614 found 14 hours ago
American Airlines
Fri, Jul 10 - Wed, Jul 15
TPA
Tampa Intl.
CGI
Cape Girardeau Municipal
$615 Roundtrip, found 4 days ago
$615
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Jul 10 from Tampa Intl. to Cape Girardeau Municipal, returning Wed, Jul 15, priced at $615 found 4 days ago
United
Sat, Jul 11 - Sat, Jul 18
TPA
Tampa Intl.
CGI
Cape Girardeau Municipal
$617 Roundtrip, found 6 days ago
$617
Roundtrip
found 6 days ago
Select United flight, departing Sat, Jul 11 from Tampa Intl. to Cape Girardeau Municipal, returning Sat, Jul 18, priced at $617 found 6 days ago

Cheap Flights to East Prairie

Fall in love at first flight with your vacation to East Prairie by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to East Prairie on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in East Prairie, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to East Prairie

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to East Prairie with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CGI airport.

What is the cheapest month to fly to East Prairie?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to East Prairie are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to East Prairie?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to East Prairie.

What airport is best to fly into East Prairie?

When you’re planning your trip to East Prairie, convenience is the name of the game. Luckily, East Prairie Cairo Regional Airport is nearby so you can deplane and get going on checking off everything on your East Prairie must-do list.

How much are flights to East Prairie?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to East Prairie on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $518, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to East Prairie?

The trick to saving a stack of cash on your flight to East Prairie? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $518 right now, why wait?

East Prairie Flight Information
Destination airport
Cape Girardeau Municipal
Destination airport IATA code
CGI
Roundtrip price
$518

Last Minute Hotel Deals in East Prairie

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,002 reviews)
We will definitely be back! We travel from Wisconsin to Texas at least 2 times a year to visit family and we like to break our trip up with an overnight stay. This Drury Inn in Siikeston, Missouri will be our home away from

Reviewed on Mar 28, 2026

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Drury Inn & Suites Sikeston, MO
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
9/10 Wonderful! (517 reviews)
The hotel was very clean and nice. The staff were friendly. It was the other people staying in the hotel that they did not control my 6 year old daughter almost got hit in the face with a volleyball and they were running through the halls and screaming all night.

Reviewed on Mar 29, 2026

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Hampton Inn Sikeston
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,000 reviews)
Room was clean, breakfast was good, staff was friendly

Reviewed on Mar 27, 2026

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Best Western Plus Sikeston I-55
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 out of 5
100 Matthews Lane Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (755 reviews)
Stayed here as we were just passing through the area. Room was clean. Pillows were not very soft. Breakfast was very limited. Was as expected for the price.

Reviewed on Mar 28, 2026

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Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,000 reviews)
There were roaches crawling up the wall when we went in and the outside was horrible! Looked like a vacant building!! I want my money back

Reviewed on Mar 24, 2026

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Days Inn and Suites by Wyndham Sikeston
Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America

2.5 out of 5
1111 BLue Heron Lane Union City TN
Book a stay at this business-friendly hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Discovery Park of America and ...
9.2/10 Wonderful! (369 reviews)
Everything was great.

Reviewed on Mar 29, 2026

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Sleep Inn at Discovery Park of America
Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG

2.5 out of 5
810 BREAM BOULEVARD Union City TN
Book a stay at this business-friendly hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (317 reviews)
Everything was great

Reviewed on Mar 11, 2026

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Holiday Inn Express & Suites Union City by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 out of 5
115 Hospitality Dr Sikeston MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (451 reviews)
Clean rooms, friendly staff and convenient location.

Reviewed on Mar 23, 2026

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Holiday Inn Express & Suites Sikeston Southwest by IHG
See all 87 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.