Search Cheap Flights to
East Prairie

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Cheap Flights to East Prairie

Fall in love at first flight with your vacation to East Prairie by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to East Prairie on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in East Prairie, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to East Prairie

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to East Prairie with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CGI airport.

What is the cheapest month to fly to East Prairie?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to East Prairie are in , but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to East Prairie?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find  to choose from for your flight to East Prairie.

What airport is best to fly into East Prairie?

When you’re planning your trip to East Prairie, convenience is the name of the game. Luckily, East Prairie Cairo Regional Airport is nearby so you can deplane and get going on checking off everything on your East Prairie must-do list.

How much are flights to East Prairie?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to East Prairie on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as , you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to East Prairie?

The trick to saving a stack of cash on your flight to East Prairie? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as  right now, why wait?

East Prairie Flight Information
Destination airport
East Prairie
Destination airport IATA code
CGI

Last Minute Hotel Deals in East Prairie

Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
The price is $98 per night from Apr 20 to Apr 21
$98
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,005 reviews)
"Nice room and comfortable bed. Only complain my would be the shower head. Needed a good clean. Water pressure was also low."

Reviewed on Apr 13, 2025

Pear Tree Inn Sikeston
Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
The price is $103 per night from Apr 22 to Apr 23
$103
includes taxes & fees
Apr 22 - Apr 23
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,001 reviews)
Nice place to stay , quiet and clean
"The gentleman at the front desk was super nice , friendly and just fun when we checked in , we had a quick overnight stay in town ! Pool was clean nice and warm , the next morning breakfast was nice clean and stocked and the young lady cleaning and keeping it full was very friendly also , plus we ..."

Reviewed on Mar 30, 2025

Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
The price is $114 per night from Apr 20 to Apr 21
$114
includes taxes & fees
Apr 20 - Apr 21
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,001 reviews)
"Wonder stay! Excellent hotel."

Reviewed on Apr 13, 2025

Drury Inn & Suites Sikeston, MO
Holiday Inn Express & Suites Union City by IHG
Holiday Inn Express & Suites Union City by IHG
2.5 out of 5
810 BREAM BOULEVARD, Union City, TN
The price is $134 per night from Apr 20 to Apr 21
$134
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (257 reviews)
Excellent
"Very nice and clean. Keurig coffee makers and Dove shampoo and soap, in the rooms. Warm indoor swimming. Nice breakfast with bacon, sausage, and biscuits. It is right next to the Discovery Museum."

Reviewed on Apr 3, 2025

Holiday Inn Express & Suites Union City by IHG
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 out of 5
1240 Commerce Drive, Sikeston, MO
The price is $143 per night from Apr 27 to Apr 28
$143
includes taxes & fees
Apr 27 - Apr 28
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (330 reviews)
"Staff was really nice"

Reviewed on Apr 10, 2025

Hampton Inn Sikeston
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
The price is $92 per night from Apr 20 to Apr 21
$92
includes taxes & fees
Apr 20 - Apr 21
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,003 reviews)
"Very accommodating staff"

Reviewed on Apr 10, 2025

Days Inn and Suites by Wyndham Sikeston
New Orleans Inn Portageville
New Orleans Inn Portageville
2.5 out of 5
600 US-61, Portageville, MO
The price is $68 per night from Apr 20 to Apr 21
$68
includes taxes & fees
Apr 20 - Apr 21
Stay at this motel in Portageville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (645 reviews)
"Good"

Reviewed on Apr 5, 2025

New Orleans Inn Portageville
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 out of 5
100 Matthews Lane, Sikeston, MO
The price is $92 per night from May 9 to May 10
$92
includes taxes & fees
May 9 - May 10
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (646 reviews)
"Inside hallways. Sink had a leak."

Reviewed on Mar 30, 2025

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.