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East Prairie

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East Prairie Flights as Low as $502

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$502 Roundtrip, found 4 days ago
$502
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $502 found 4 days ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$511 Roundtrip, found 4 days ago
$511
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $511 found 4 days ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$518 Roundtrip, found 4 days ago
$518
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $518 found 4 days ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$521 Roundtrip, found 4 days ago
$521
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $521 found 4 days ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$528 Roundtrip, found 4 days ago
$528
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $528 found 4 days ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$537 Roundtrip, found 1 day ago
$537
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $537 found 1 day ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$546 Roundtrip, found 4 days ago
$546
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $546 found 4 days ago
American Airlines
Fri, Aug 22 - Mon, Aug 25
DEN
Denver Intl.
PAH
Barkley Regional
$567 Roundtrip, found 6 days ago
$567
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Aug 22 from Denver Intl. to Barkley Regional, returning Mon, Aug 25, priced at $567 found 6 days ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$576 Roundtrip, found 1 day ago
$576
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $576 found 1 day ago
American Airlines
Fri, Aug 22 - Mon, Aug 25
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$594 Roundtrip, found 6 days ago
$594
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Aug 22 from Dallas-Fort Worth Intl. to Barkley Regional, returning Mon, Aug 25, priced at $594 found 6 days ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$596 Roundtrip, found 4 days ago
$596
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $596 found 4 days ago
American Airlines
Fri, Aug 22 - Mon, Aug 25
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$604 Roundtrip, found 6 days ago
$604
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Aug 22 from Dallas-Fort Worth Intl. to Barkley Regional, returning Mon, Aug 25, priced at $604 found 6 days ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$606 Roundtrip, found 4 days ago
$606
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $606 found 4 days ago
United
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$611 Roundtrip, found 4 days ago
$611
Roundtrip
found 4 days ago
Select United flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $611 found 4 days ago
American Airlines
Fri, Aug 22 - Mon, Aug 25
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$615 Roundtrip, found 6 days ago
$615
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Aug 22 from Dallas-Fort Worth Intl. to Barkley Regional, returning Mon, Aug 25, priced at $615 found 6 days ago
American Airlines
Fri, Aug 22 - Mon, Aug 25
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$625 Roundtrip, found 6 days ago
$625
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Aug 22 from Dallas-Fort Worth Intl. to Barkley Regional, returning Mon, Aug 25, priced at $625 found 6 days ago

Cheap Flights to East Prairie

Fall in love at first flight with your vacation to East Prairie by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to East Prairie on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in East Prairie, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to East Prairie

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to East Prairie with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the CGI airport.

What is the cheapest month to fly to East Prairie?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to East Prairie are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to East Prairie?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to East Prairie.

What airport is best to fly into East Prairie?

When you’re planning your trip to East Prairie, convenience is the name of the game. Luckily, East Prairie Cairo Regional Airport is nearby so you can deplane and get going on checking off everything on your East Prairie must-do list.

How much are flights to East Prairie?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to East Prairie on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $502, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to East Prairie?

The trick to saving a stack of cash on your flight to East Prairie? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $502 right now, why wait?

East Prairie Flight Information
Destination airport
Barkley Regional
Destination airport IATA code
PAH
Roundtrip price
$502

Last Minute Hotel Deals in East Prairie

Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive, Sikeston, MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,000 reviews)
I would stay again
"We did not use the internet or have the breakfast so I have no feedback on those. The room seemed clean and so did the bathroom. The bathroom did have some paint peeling in one spot. The worst thing I can say is the mattress was firmer than I like. The hotel was quiet, easily accessible, equipped ..."

Reviewed on Aug 10, 2025

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Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,001 reviews)
"Great location"

Reviewed on Aug 14, 2025

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Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,001 reviews)
"The staff were all great and happy to accommodate us when we asked to switch rooms due to an AC issue in our original room. The beds were comfortable and clean. No bugs in sight, which is a big thing for me when staying in hotels. Everything was very outdated, the rooms could definitely benefit from ..."

Reviewed on Aug 8, 2025

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Days Inn and Suites by Wyndham Sikeston
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,004 reviews)
"Very nice property Friendly helpful staff"

Reviewed on Aug 16, 2025

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Pear Tree Inn Sikeston
Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51

2.5 out of 5
1221 W Reelfoot Ave, Union City, TN
Book a stay at this business-friendly hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.8/10 (323 reviews)
It was ok
"The pool was filthy and the room floors was kinda gross . But if the house keepers did a better job it would have been a great stay. Crazy drunk guy at the pool .. pool was the reason for renting a room ."

Reviewed on Jul 7, 2025

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Hospitality House Union City I 69 / US 51
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive, Sikeston, MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (374 reviews)
"Relaxing"

Reviewed on Aug 9, 2025

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Hampton Inn Sikeston
Quality Inn Union City US 51

Quality Inn Union City US 51

2.5 out of 5
2201 W Reelfoot Ave, Union City, TN
Stay at this hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.2/10 Very Good! (462 reviews)
"Nice place. Everything went as should and no hidden fees."

Reviewed on Jul 28, 2025

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Quality Inn Union City US 51
Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG

2.5 out of 5
810 BREAM BOULEVARD, Union City, TN
Book a stay at this business-friendly hotel in Union City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (284 reviews)
"This is new and perfect facility. Loved it."

Reviewed on Aug 3, 2025

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Holiday Inn Express & Suites Union City by IHG
See all 80 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.