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Hotels in Sikeston

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Check Last Minute Sikeston Hotel Deals

Tonight Sep 27 - Sep 28This weekend Sep 27 - Sep 29

Choose from 266 Sikeston Hotel Deals

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
  • 7 min walk from The Book Bug
The price is $77 per night from Oct 14 to Oct 15
$77
includes taxes & fees
Oct 14 - Oct 15
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,000 reviews)
"Clean, large room"

Reviewed on Sep 17, 2024

Days Inn and Suites by Wyndham Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Sikeston, MO
  • 4 min walk from The Book Bug
The price is $112 per night from Oct 6 to Oct 7
$112
includes taxes & fees
Oct 6 - Oct 7
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,001 reviews)
"Great stay"

Reviewed on Sep 22, 2024

Drury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
  • 3 min walk from The Book Bug
The price is $93 per night from Oct 1 to Oct 2
$93
includes taxes & fees
Oct 1 - Oct 2
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,001 reviews)
Women’s Conference
"I recommend Pear Tree Inn, it is reasonably priced, the room was comfortable, the staff was friendly and helpful. It is located with easy access to the interstate."

Reviewed on Sep 22, 2024

Pear Tree Inn Sikeston
Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
  • 7 min walk from The Book Bug
The price is $97 per night from Sep 29 to Sep 30
$97
includes taxes & fees
Sep 29 - Sep 30
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,004 reviews)
Don’t totally rule out.
"Check in was very pleasant. The woman at the front desk was very nice. Arrived to our room and it was warm and stuffy. Dropped our bags, turned temperature down and went to eat. Came back and all was cool. As far as the room being clean- there was a piece of tile by the tub floor off the wall laying ..."

Reviewed on Sep 23, 2024

Best Western Plus Sikeston
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 out of 5
100 Matthews Lane, Sikeston, MO
  • 2 min walk from The Book Bug
The price is $72 per night from Sep 29 to Sep 30
$72
includes taxes & fees
Sep 29 - Sep 30
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (585 reviews)
"Decent place for a one-night stay."

Reviewed on Sep 21, 2024

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 out of 5
1240 Commerce Drive, Sikeston, MO
  • 7 min drive from The Book Bug
The price is $134 per night from Oct 27 to Oct 28
$134
includes taxes & fees
Oct 27 - Oct 28
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (291 reviews)
"Excellent location"

Reviewed on Sep 22, 2024

Hampton Inn Sikeston
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
2.5 out of 5
115 Hospitality Dr, Sikeston, MO
  • 7 min drive from The Book Bug
The price is $139 per night from Oct 13 to Oct 14
$139
includes taxes & fees
Oct 13 - Oct 14
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (369 reviews)
"The continental breakfast"

Reviewed on Sep 23, 2024

Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
Country Yard Inn and Suite
Country Yard Inn and Suite
2 out of 5
110 South Interstate Drive, Sikeston, MO
  • 8 min walk from The Book Bug
The price is $69 per night from Sep 28 to Sep 29
$69
includes taxes & fees
Sep 28 - Sep 29
Stay at this motel in Sikeston. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions The Book Bug and Boot Heel Golf Club are located ...
7.2/10 Good! (49 reviews)
"I would definitely stay here again!!! Thank you"

Reviewed on Sep 4, 2024

Country Yard Inn and Suite
Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55
2.5 out of 5
109 Matthews Ln, Sikeston, MO
  • 2 min walk from The Book Bug
The price is $90 per night from Oct 13 to Oct 14
$90
includes taxes & fees
Oct 13 - Oct 14
Book a stay at this business-friendly hotel in Sikeston. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (220 reviews)
Perfect Pit Stop
"Check in was easy with friendly staff. Hotel had everything you would need, plus walking distance to dining."

Reviewed on Sep 19, 2024

Comfort Inn & Suites Sikeston I-55
Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner Area
2 out of 5
2609 E Malone Ave, Sikeston, MO
  • 3 min walk from The Book Bug
The price is $68 per night from Sep 30 to Oct 1
$68
includes taxes & fees
Sep 30 - Oct 1
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions The Book Bug and Boot Heel Golf ...
6.4/10 (496 reviews)
"Good"

Reviewed on Aug 3, 2024

Super 8 by Wyndham Sikeston/Miner Area
Auburn Place Hotel And Suites
Auburn Place Hotel And Suites
2.5 out of 5
3265 William St, Cape Girardeau, MO
  • 1 hour drive from The Book Bug
The price is $89 per night from Sep 29 to Sep 30
$89
includes taxes & fees
Sep 29 - Sep 30
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
8.8/10 Excellent! (1,000 reviews)
"Great hotel especially for the rate. Friendly staff. Great location. I lived in Cape 50 years ago and this was a nice place to stay for my 50th high school reunion."

Reviewed on Sep 23, 2024

Auburn Place Hotel And Suites
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
  • 1 hour drive from The Book Bug
The price is $71 per night from Oct 2 to Oct 3
$71
includes taxes & fees
Oct 2 - Oct 3
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,003 reviews)
"Great stay clean room with great staff."

Reviewed on Sep 22, 2024

Pear Tree Inn Cape Girardeau Near the Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Sikeston

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Sikeston.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Sikeston’s 266 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $68. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Sikeston hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Sikeston. No matter your reason for visiting Sikeston, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Sikeston hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Sikeston for as low as $68.

How many hotels are there in Sikeston?

With over 266 hotels in Sikeston, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $68.

How to find cheap car rentals in Sikeston?

Finding a cheap car rental deal in Sikeston is as easy as scoring cheap hotels in Sikeston. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Sikeston now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Sikeston right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.