Search for Cheap Deals onKid-Friendly Hotels in Sikeston
Photo by Ryan Coleman
You choose what matters — star rating, location, amenities.
We pick the perfect hotel, packed with all your must-haves.
Your hotel is revealed right after booking!
Featured Sikeston Family Hotels
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
Drury Inn & Suites Cape Girardeau
3303 Campster Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd, Jackson, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
Drury Inn & Suites Jackson MO
225 Drury Lane, Jackson, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street, Cape Girardeau, MO
Fully refundable
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Dexter Inn
1807 W Business US Highway 60, Dexter, MO
Fully refundableReserve now, pay when you stay
Stay at this hotel in Dexter. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions The ...
Quality Inn Charleston - Sikeston
102 Drake St, I-57 Exit 10, Charleston, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
Hampton Inn Cape Girardeau I 55 East
207 S Mt Auburn Rd, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels with Pools in Sikeston
Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,001 reviews)
"Great"
Reviewed on Mar 9, 2025
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,001 reviews)
"I was hoping to use my One Cash $ but could not figure out how to do it."
Reviewed on Mar 10, 2025
Drury Inn & Suites Jackson MO
225 Drury Lane, Jackson, MO
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,000 reviews)
"Excellent experience!"
Reviewed on Mar 8, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels With Connecting Rooms in Sikeston
Drury Inn & Suites Cape Girardeau
3303 Campster Drive, Cape Girardeau, MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Drury Inn & Suites Jackson MO
225 Drury Lane, Jackson, MO
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options
- Hotels with Free Parking in Sikeston
- Pet-friendly Hotels in Sikeston
- Hotels with a Pool in Sikeston
- Hotels with an Indoor Pool in Sikeston
- Hotels with Hot Tubs in Sikeston
- Casinos in Sikeston
- Luxury Hotels in Sikeston
- Hotel Wedding Venues in Sikeston
- Apartment Hotel in Sikeston
- Historic Hotels in Sikeston
Top Points of Interests in Sikeston
- Hotels near Boot Heel Golf Club
- Hotels near Sikeston Depot Museum
- Hotels near The Book Bug
- Hotels near Central Park
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Ohio River
- Hotels near Southeast Missouri State University
- Hotels near Riverfront Bridge Park
- Hotels near Riverfront Park
- Hotels near Big Oak Tree State Park
- Hotels near New Madrid Historical Museum
- Hotels near Fort Defiance State Park
- Hotels near eDen Spa & Salon
- Hotels near Fort D Historic Site
- Hotels near Stoddard County Civil War Memorial Cemetery
- Hotels near Mound City National Cemetery
- Hotels near Dexter Welcome Center Depot and Museum
- Hotels near Hunter-Dawson State Historic Site
- Hotels near Marston Community Center
Cities near Sikeston
- Cape Girardeau Hotels (29.82 mi)
- Ozarks Hotels (161.27 mi)
- Southern Illinois Hotels (113.94 mi)
- Southeastern United States Hotels (420.75 mi)
- Central United States Hotels (267.86 mi)
- Dexter Hotels (21.18 mi)
- Tiptonville Hotels (35.09 mi)
- Marston Hotels (24.82 mi)
- Charleston Hotels (13.59 mi)
- Portageville Hotels (31.83 mi)
- Western Kentucky Hotels (109.03 mi)
- Western Tennessee Hotels (89.28 mi)
- Southeast Missouri Hotels (51.94 mi)
- Cairo Hotels (24.44 mi)
- The South Hotels (242.82 mi)
- New Madrid Hotels (20.41 mi)
- Malden Hotels (30.43 mi)
- East Prairie Hotels (13.15 mi)
Car Rentals Near Sikeston
- Car rentals in Cape Girardeau
- Car rentals in Ozarks
- Car rentals in Southern Illinois
- Car rentals in Southeastern United States
- Car rentals in Central United States
- Car rentals in Dexter
- Car rentals in Tiptonville
- Car rentals in Marston
- Car rentals in Charleston
- Car rentals in Portageville
- Car rentals in Western Kentucky
- Car rentals in Western Tennessee
- Car rentals in Southeast Missouri
- Car rentals in Cairo
- Car rentals in The South
- Car rentals in New Madrid
Top Family Hotel Destinations
- Las Vegas Family Hotels
- Arcade Family Hotels
- Branson Family Hotels
- Biloxi Family Hotels
- Ocean City Family Hotels
- Orlando Family Hotels
- Buffalo Family Hotels
- Reno Family Hotels
- Colorado Springs Family Hotels
- Phoenix Family Hotels
- Niagara Falls Family Hotels
- New York Family Hotels
- Whistler Family Hotels
- Houston Family Hotels
- Fort Walton Beach Family Hotels
- Pensacola Beach Family Hotels
- Tampa Family Hotels
- Myrtle Beach Family Hotels
- Miami Beach Family Hotels
- Birmingham Family Hotels
Top Booked Hotels in Sikeston
- Days Inn and Suites by Wyndham Sikeston
- Best Western Plus Sikeston
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Holiday Inn Express & Suites Sikeston Southwest by IHG
- Hampton Inn Sikeston
- Super 8 by Wyndham Sikeston/Miner Area
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Candlewood Suites Cape Girardeau by IHG