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Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
  • 4 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,012 reviews)
Clean, comfortable room, plentiful parking, nice warm breakfast.

Reviewed on Mar 7, 2026

Drury Inn & Suites Sikeston, MO
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
  • 4 hours drive from Mark Twain National Forest
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
9/10 Wonderful! (494 reviews)
Good room and helpful staff

Reviewed on Mar 2, 2026

Hampton Inn Sikeston
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 out of 5
100 Matthews Lane Sikeston MO
  • 4 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (749 reviews)
Very clean but sometimes noisy from outside traffic

Reviewed on Mar 6, 2026

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
  • 4 hours drive from Mark Twain National Forest
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,005 reviews)
We started our stay with a hostile guest while trying to check in. The lack of care from the worker at check in was a new level of IDGAF, the following day they turned our

Reviewed on Mar 2, 2026

Best Western Plus Sikeston I-55
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
  • 4 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,005 reviews)
Fantastic room and super friendly staff. Hotel was way better than I expected. It was comfortable and clean with a great shower!

Reviewed on Mar 6, 2026

Days Inn and Suites by Wyndham Sikeston
Country Yard Inn and Suite

Country Yard Inn and Suite

2 out of 5
110 South Interstate Drive Sikeston MO
  • 4 hours drive from Mark Twain National Forest
Stay at this motel in Sikeston. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Central Park and Sikeston Depot Museum are located ...
6.8/10 (126 reviews)
I love this hotel.

Reviewed on Mar 3, 2026

Country Yard Inn and Suite
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

2.5 out of 5
2179 Gill Plaza Drive Dexter MO
  • 4 hours drive from Mark Twain National Forest
Stay at this hotel in Dexter. Popular attractions The Heritage House and Keller Veteran Memorial are located nearby.
10/10 Exceptional! (15 reviews)
Very pleasant experience

Reviewed on Mar 6, 2026

Hampton Inn By Hilton Dexter
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 out of 5
115 Hospitality Dr Sikeston MO
  • 4 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (449 reviews)
Nice room

Reviewed on Mar 5, 2026

Holiday Inn Express & Suites Sikeston Southwest by IHG
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2 out of 5
2609 E Malone Ave Sikeston MO
  • 4 hours drive from Mark Twain National Forest
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot Museum are located ...
6.8/10 (600 reviews)
Staff was friendly and helpful but the towels in the bathroom seem like they had dodo stains. And the shower was hard to figure out.

Reviewed on Feb 26, 2026

Super 8 by Wyndham Sikeston/Miner Area
Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter

2 out of 5
1608 E Business US 60 Dexter MO
  • 4 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Dexter. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions The Heritage House and Keller ...
7.6/10 Good! (395 reviews)
Clean and quiet

Reviewed on Feb 10, 2026

Travelodge by Wyndham Dexter
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

3 out of 5
1239 Commerce Drive Sikeston MO
  • 4 hours drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
9.4/10 Exceptional! (62 reviews)
Loved the hotel. Comfortable bed, super clean room and bathroom was great.

Reviewed on Mar 7, 2026

Fairfield Inn & Suites by Marriott Sikeston
Dexter Inn

Dexter Inn

2.5 out of 5
1807 W Business US Highway 60 Dexter MO
  • 4 hours drive from Mark Twain National Forest
Stay at this hotel in Dexter. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions The ...
7/10 Good! (336 reviews)
Plenty of food options

Reviewed on Mar 3, 2026

Dexter Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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