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Tonight Jun 26 - Jun 27This weekend Jun 26 - Jun 28

Choose from 43 Bernie Hotel Deals

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2.5 out of 5
2420 Crestwood Dr Poplar Bluff MO
  • 8 hours drive from Mississippi River
Stay at this hotel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.4/10 Exceptional! (879 reviews)
"Great service, room and breakfast! Only issue was one elevator was out of service which made the other elevator slow."

Reviewed on Jun 26, 2026

Hampton Inn Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

3 out of 5
3109 Oak Grove Poplar Bluff MO
  • 8 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (924 reviews)
"Great place, clean, friendly staff, breakfast was great!"

Reviewed on Jun 23, 2026

Fairfield Inn & Suites by Marriott Poplar Bluff
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

3 out of 5
2220 N Westwood Blvd Poplar Bluff MO
  • 8 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,001 reviews)
"This place was great it was out last stay on our road trip it was clean and quiet with extremely friendly staff. The meals were wonderful and the bed was soft.. definitely a wonderful stop along the way"

Reviewed on Jun 18, 2026

Drury Inn & Suites Poplar Bluff
Lake Wappapello

Lake Wappapello

2 out of 5
8005 Missouri 172 Williamsville MO
  • 7 hours drive from Mississippi River
Stay at this cabin in Williamsville. Enjoy free parking. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located ...
8.8/10 Excellent! (3 reviews)
"I had a reservation for 4 nights, also received a confermation and itinerary number from hotes.com, but upon arrival I found that hotels.cim never made the reservation with the place I was staying. The place i was supposed to stay at were as accommodating as they could be, tried to find me a place ..."

Reviewed on Jun 19, 2026

Lake Wappapello
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

3 out of 5
2781 N Westwood Blvd Poplar Bluff MO
  • 8 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Poplar Bluff. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
8.8/10 Excellent! (747 reviews)
"Staff was very friendly and helpful. There is an attached restaurant serving breakfast and dinner. The hotel, although clean, is a bit dated. Rooms, as well as the hotel overall could use a face lift."

Reviewed on Jun 21, 2026

Holiday Inn Poplar Bluff by IHG
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

2.5 out of 5
2179 Gill Plaza Drive Dexter MO
  • 8 hours drive from Mississippi River
Stay at this hotel in Dexter. Enjoy a fitness center, a 24-hour front desk, and a business center. Popular attractions The Heritage House and Keller Veteran ...
9.8/10 Exceptional! (41 reviews)
"This hotel was a lot newer than we expected! It had an nice, private outdoor pool and patio area that was tucked behind the hotel. Pool towels are not openly offered. You need to check them in and out at the front desk. Their incidental charge is high and takes a long time to be cleared off. We enjoyed ..."

Reviewed on Jun 22, 2026

Hampton Inn By Hilton Dexter
New Orleans Inn Portageville

New Orleans Inn Portageville

2.5 out of 5
600 US-61 Portageville MO
  • 9 hours drive from Mississippi River
Stay at this motel in Portageville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (776 reviews)
"Don't let the outside make you turn away. They are in the process of remodeling. My husband must have a firm mattress. Missy, a lovely person, has a broken ankle, so her employee, Donna, led us to the room, so Rich could check the bed. It was perfect. The carpet had been recently cleaned. We had ..."

Reviewed on Jun 23, 2026

New Orleans Inn Portageville
Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

2 out of 5
2831 N Westwood Blvd Poplar Bluff MO
  • 8 hours drive from Mississippi River
Book a stay at this business-friendly motel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Popular attractions North Main Street Historic ...
6.6/10 (651 reviews)
"The place was clean and the bed was comfy. Room was updated."

Reviewed on Jun 25, 2026

Super 8 by Wyndham Poplar Bluff Missouri
Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter

2 out of 5
1608 E Business US 60 Dexter MO
  • 8 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Dexter. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions The Heritage House and Keller ...
7.6/10 Good! (411 reviews)
"Twice during our stay someone unlocked and opened the door with only the security lock stopping them."

Reviewed on Jun 5, 2026

Travelodge by Wyndham Dexter
Econo Lodge Dexter

Econo Lodge Dexter

2 out of 5
913 Outer Rd Dexter MO
  • 8 hours drive from Mississippi River
Book a stay at this business-friendly motel in Dexter. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
6.8/10 (270 reviews)
"It stinks and frebreeze don't help. Needs aired out!"

Reviewed on Jun 26, 2026

Econo Lodge Dexter
Dexter Inn

Dexter Inn

2.5 out of 5
1807 W Business US Highway 60 Dexter MO
  • 8 hours drive from Mississippi River
Stay at this hotel in Dexter. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions The ...
7/10 Good! (351 reviews)
"Wonderful staff! So helpful"

Reviewed on Jun 23, 2026

Dexter Inn
Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North

2.5 out of 5
2582 N Westwood Blvd Poplar Bluff MO
  • 8 hours drive from Mississippi River
Book a stay at this business-friendly hotel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (420 reviews)
"The staff was very friendly and accommodating. But our room smelled strongly of urine."

Reviewed on Jun 25, 2026

Comfort Inn Poplar Bluff North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Bernie

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Frequently Asked Questions About Bernie hotels

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How many hotels are there in Bernie?

With over 43 hotels in Bernie, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $57.

How to find cheap car rentals in Bernie?

Finding a cheap car rental deal in Bernie is as easy as scoring cheap hotels in Bernie. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.