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Hotels in Poplar Bluff

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Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N Poplar Bluff MO
  • 24 min walk from Poplar Bluff Regional Medical Center
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,001 reviews)
There wasnt an indoor pool and no breakfast offered. Hotel room was clean and comfortable. Small kitchenette. Perfect for the few days we were there.

Reviewed on Jan 17, 2026

Motel 6 Poplar Bluff, MO
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

2.5 out of 5
3109 Oak Grove Poplar Bluff MO
  • 3 min walk from Poplar Bluff Regional Medical Center
Book a stay at this business-friendly hotel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (866 reviews)
Yes

Reviewed on Jan 17, 2026

Fairfield Inn & Suites by Marriott Poplar Bluff
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

3 out of 5
2220 N Westwood Blvd Poplar Bluff MO
  • 18 min walk from Poplar Bluff Regional Medical Center
Book a stay at this business-friendly hotel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (980 reviews)
Great location and room

Reviewed on Jan 9, 2026

Drury Inn & Suites Poplar Bluff
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

3 out of 5
2781 N Westwood Blvd Poplar Bluff MO
  • 10 min walk from Poplar Bluff Regional Medical Center
Book a stay at this business-friendly hotel in Poplar Bluff. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
8.6/10 Excellent! (714 reviews)
The front desk woman was great

Reviewed on Dec 21, 2025

Holiday Inn Poplar Bluff by IHG
Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

2 out of 5
2831 N Westwood Blvd Poplar Bluff MO
  • 10 min walk from Poplar Bluff Regional Medical Center
Book a stay at this business-friendly motel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Popular attractions North Main Street Historic ...
6.4/10 (633 reviews)
Will be staying again. Thank you

Reviewed on Jan 18, 2026

Super 8 by Wyndham Poplar Bluff Missouri
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2.5 out of 5
2420 Crestwood Dr Poplar Bluff MO
  • 13 min walk from Poplar Bluff Regional Medical Center
Stay at this hotel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.2/10 Wonderful! (798 reviews)
Staff was very helpful

Reviewed on Dec 31, 2025

Hampton Inn Poplar Bluff
Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North

2.5 out of 5
2582 N Westwood Blvd Poplar Bluff MO
  • 16 min walk from Poplar Bluff Regional Medical Center
Book a stay at this business-friendly hotel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (401 reviews)
Room was clean and staff was great! Also, breakfast was great! Only draw back was heater thermostat didn't work right. I had to turn it off to not get too hot. Didn't work to turn down. I reported it, and they said they would look into it.

Reviewed on Dec 22, 2025

Comfort Inn Poplar Bluff North
Bullwinkles Rustic Lodge

Bullwinkles Rustic Lodge

2.5 out of 5
399 Hwy T Poplar Bluff MO
  • 7 min drive from Poplar Bluff Regional Medical Center
Book a stay at this business-friendly hotel in Poplar Bluff. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (213 reviews)
A work buddy, and I stayed for 3 nights. Accommodation was very good and we will stay again. When in the area.

Reviewed on Mar 14, 2025

Bullwinkles Rustic Lodge
40-acre Poplar Bluff Nature Lovers Paradise!

40-acre Poplar Bluff Nature Lovers Paradise!

3 out of 5
Poplar Bluff MO
  • 8 min drive from Poplar Bluff Regional Medical Center
Stay at this cottage in Poplar Bluff. Enjoy free parking, patios, and in-room fireplaces.
10/10 Exceptional! (3 reviews)
Beautiful place enjoyed our stay

Reviewed on Apr 4, 2025

40-acre Poplar Bluff Nature Lovers Paradise!
Waterfront Home Near Mark Twain National Forest

Waterfront Home Near Mark Twain National Forest

3.5 out of 5
Poplar Bluff MO
  • 4 min drive from Poplar Bluff Regional Medical Center
Book a stay at this business-friendly apartment in Poplar Bluff. Enjoy free parking and air conditioning. Popular attractions Ozark Ridge Golf Course and North ...
Waterfront Home Near Mark Twain National Forest
Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter

2 out of 5
1608 E Business US 60 Dexter MO
  • 48 min drive from Poplar Bluff Regional Medical Center
Book a stay at this business-friendly hotel in Dexter. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions The Heritage House and Keller ...
7.4/10 Good! (391 reviews)
Everything is nice accept the Direct tv never works and their internet is terrible. Other than those 2 things it has been pleasant staying here. The manager corrected the problem with our checking in and the staff not knowing what to do. The cleaning staff is very nice and accommodating. The room ...

Reviewed on Jan 10, 2026

Travelodge by Wyndham Dexter
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

2.5 out of 5
2179 Gill Plaza Drive Dexter MO
  • 46 min drive from Poplar Bluff Regional Medical Center
Stay at this hotel in Dexter. Popular attractions The Heritage House and Keller Veteran Memorial are located nearby.
10/10 Exceptional! (8 reviews)
The hotel and staff were amazing! The only thing I would change is better lighting and direction for the entrances to the parking areas. 10/10 will be staying again!

Reviewed on Jan 12, 2026

Hampton Inn By Hilton Dexter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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