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Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,011 reviews)
"Great"
Reviewed on Jul 15, 2025

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,006 reviews)
"The staff here from check in to the morning breakfast were welcoming and friendly. Cost was reasonable. I loved seeing the dogs and that it is pet friendly. Everything was clean. The location was close to places to eat - we even walked to El Bracero for dinner. I would highly recommend"
Reviewed on Jul 11, 2025

Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,000 reviews)
"Would have appreciated a way to charge our phone. We had our cord but nowhere to put it. Maybe a clock with the port for charging? The faucet leaked in the sink. Everything else was great."
Reviewed on Jul 15, 2025

Hampton Inn Sikeston
1240 Commerce Drive, Sikeston, MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (361 reviews)
"Not bad"
Reviewed on Jul 6, 2025

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,000 reviews)
Keep up the renovations
"This hotel looked like an old apartment building renovation into a hotel with much wrk in progress. Decent stay. Spacious. Very minimal breakfast offerings. The geese outside sure left messes everywhere but the greeting cat was a nice touch"
Reviewed on Jun 28, 2025
Fairfield by Marriott Inn & Suites Sikeston
1239 Commerce Drive, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
9.8/10 Exceptional! (14 reviews)
"The staff was amazing. Hotel was beautiful"
Reviewed on Jul 13, 2025

Quality Inn Charleston - Sikeston
102 Drake St, I-57 Exit 10, Charleston, MO
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
6.8/10 (389 reviews)
"Our room was spacious and bed was comfortable, took a while to cool down but eventually did, enjoyed the in-room coffee."
Reviewed on Jun 22, 2025

Comfort Inn & Suites Sikeston I-55
109 Matthews Ln, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (268 reviews)
"It was cool"
Reviewed on Jun 24, 2025

Super 8 by Wyndham Charleston/Sikeston East MO
310 S Story St, Charleston, MO
Stay at this motel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews.
6.6/10 (571 reviews)
"A great surprise in Owasso! Great price and excellent room. So impressed."
Reviewed on Jul 6, 2025

Country Yard Inn and Suite
110 South Interstate Drive, Sikeston, MO
Stay at this motel in Sikeston. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Central Park and Sikeston Depot Museum are located ...
7/10 Good! (96 reviews)
"Good but WiFi weak"
Reviewed on Apr 10, 2025

Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (412 reviews)
"People were friendly and helpful. Room was clean"
Reviewed on Jul 11, 2025

Super 8 by Wyndham Sikeston/Miner Area
2609 E Malone Ave, Sikeston, MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot Museum are located ...
6.6/10 (542 reviews)
Experience it yourself
"My stay was excellent the front desk was polite and the overall experience was lovely. Will return."
Reviewed on Jul 14, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Booked Hotels in Bertrand
- Best Western Plus Sikeston
- Hampton Inn Sikeston
- Days Inn and Suites by Wyndham Sikeston
- Quality Inn Charleston - Sikeston
- Super 8 by Wyndham Charleston/Sikeston East MO
- Holiday Inn Express & Suites Sikeston Southwest by IHG
- Super 8 by Wyndham Sikeston/Miner Area
- Quality Inn Cairo I-57
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Ohio River
- Hotels near Columbus-Belmont State Park
- Hotels near Fort Defiance State Park
- Hotels near Big Oak Tree State Park
- Hotels near Sikeston Depot Museum
- Hotels near Mound City National Cemetery
- Hotels near River Ridge Winery
- Hotels near New Madrid Historical Museum
- Hotels near Central Park
- Hotels near Hunter-Dawson State Historic Site
- Hotels near Ballard Wildlife Management Area
- Hotels near Front Street Studio & Art Gallery
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- Sikeston Hotels
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- Charleston Hotels
- Cairo Hotels
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- Western Kentucky Hotels
- Southeast Missouri Hotels
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- Bardwell Hotels
- Tamms Hotels