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Sikeston

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Sikeston Flights as Low as $128

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Thu, Jun 12 - Sat, Jun 14
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$128 Roundtrip, found 4 days ago
$128
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Jun 12 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Jun 14, priced at $128 found 4 days ago
Frontier Airlines
Thu, Jun 12 - Sun, Jun 15
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$148 Roundtrip, found 4 days ago
$148
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Jun 12 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sun, Jun 15, priced at $148 found 4 days ago
Spirit Airlines
Tue, Apr 15 - Tue, Apr 22
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$169 Roundtrip, found 3 days ago
$169
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Tue, Apr 15 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Apr 22, priced at $169 found 3 days ago
Spirit Airlines
Tue, Apr 22 - Tue, Apr 29
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$179 Roundtrip, found 5 days ago
$179
Roundtrip
found 5 days ago
Select Spirit Airlines flight, departing Tue, Apr 22 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Apr 29, priced at $179 found 5 days ago
Frontier Airlines
Wed, Jun 11 - Thu, Jun 12
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$181 Roundtrip, found 4 days ago
$181
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Wed, Jun 11 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Thu, Jun 12, priced at $181 found 4 days ago
American Airlines
Mon, Jun 9 - Thu, Jun 12
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$183 Roundtrip, found 4 days ago
$183
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Jun 9 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Thu, Jun 12, priced at $183 found 4 days ago
Spirit Airlines
Thu, Apr 24 - Tue, Apr 29
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$189 Roundtrip, found 5 days ago
$189
Roundtrip
found 5 days ago
Select Spirit Airlines flight, departing Thu, Apr 24 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Apr 29, priced at $189 found 5 days ago
Delta
Thu, Jun 12 - Thu, Jun 12
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$192 Roundtrip, found 4 days ago
$192
Roundtrip
found 4 days ago
Select Delta flight, departing Thu, Jun 12 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Thu, Jun 12, priced at $192 found 4 days ago
Spirit Airlines
Thu, Apr 17 - Tue, Apr 22
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$197 Roundtrip, found 3 days ago
$197
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Thu, Apr 17 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Apr 22, priced at $197 found 3 days ago
Spirit Airlines
Tue, Apr 8 - Tue, Apr 15
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$207 Roundtrip, found 4 days ago
$207
Roundtrip
found 4 days ago
Select Spirit Airlines flight, departing Tue, Apr 8 from Logan Intl. to Lambert-St. Louis Intl., returning Tue, Apr 15, priced at $207 found 4 days ago
American Airlines
Mon, Jun 9 - Thu, Jun 12
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$217 Roundtrip, found 4 days ago
$217
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Jun 9 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Thu, Jun 12, priced at $217 found 4 days ago
United
Wed, Apr 16 - Sun, Apr 20
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$231 Roundtrip, found 3 days ago
$231
Roundtrip
found 3 days ago
Select United flight, departing Wed, Apr 16 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sun, Apr 20, priced at $231 found 3 days ago
Frontier Airlines
Fri, May 2 - Sat, May 3
SLC
Salt Lake City Intl.
STL
Lambert-St. Louis Intl.
$248 Roundtrip, found 1 day ago
$248
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, May 2 from Salt Lake City Intl. to Lambert-St. Louis Intl., returning Sat, May 3, priced at $248 found 1 day ago
Frontier Airlines
Tue, Apr 8 - Sat, Apr 12
BDL
Bradley Intl.
STL
Lambert-St. Louis Intl.
$249 Roundtrip, found 1 day ago
$249
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Tue, Apr 8 from Bradley Intl. to Lambert-St. Louis Intl., returning Sat, Apr 12, priced at $249 found 1 day ago
Hawaiian Airlines
Mon, May 5 - Tue, May 6
SLC
Salt Lake City Intl.
STL
Lambert-St. Louis Intl.
$392 Roundtrip, found 1 day ago
$392
Roundtrip
found 1 day ago
Select Hawaiian Airlines flight, departing Mon, May 5 from Salt Lake City Intl. to Lambert-St. Louis Intl., returning Tue, May 6, priced at $392 found 1 day ago
Alaska Airlines
Sat, May 3 - Tue, May 6
SLC
Salt Lake City Intl.
STL
Lambert-St. Louis Intl.
$454 Roundtrip, found 1 day ago
$454
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Sat, May 3 from Salt Lake City Intl. to Lambert-St. Louis Intl., returning Tue, May 6, priced at $454 found 1 day ago

Cheap Flights to Sikeston

Fall in love at first flight with your vacation to Sikeston by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Sikeston on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Sikeston, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Sikeston

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Sikeston with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Sikeston?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Sikeston are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Sikeston?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Sikeston.

What airport is best to fly into Sikeston?

When you’re planning your trip to Sikeston, convenience is the name of the game. Luckily, Sikeston Cairo Regional Airport is nearby so you can deplane and get going on checking off everything on your Sikeston must-do list.

How much are flights to Sikeston?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Sikeston on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $128, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Sikeston?

The trick to saving a stack of cash on your flight to Sikeston? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $128 right now, why wait?

Sikeston Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$268

Last Minute Hotel Deals in Sikeston

Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
The price is $98 per night from Apr 1 to Apr 2
$98
includes taxes & fees
Apr 1 - Apr 2
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,000 reviews)
"Very nice hotel. Except when we went to the hot tub, there was a bowel movement in the water. Didn't notice till we got out. Reported to hotel staff."

Reviewed on Mar 23, 2025

Pear Tree Inn Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
The price is $114 per night from Apr 6 to Apr 7
$114
includes taxes & fees
Apr 6 - Apr 7
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,001 reviews)
"Night time snacks were a perfect dinner option for us! Great breakfast to get us on the road for a long travel day. Very nice accommodations."

Reviewed on Mar 23, 2025

Drury Inn & Suites Sikeston, MO
Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
The price is $107 per night from Mar 30 to Mar 31
$107
includes taxes & fees
Mar 30 - Mar 31
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,001 reviews)
"It was a very late arrival and they were very accomodating. Friendly staff. Very good breakfast."

Reviewed on Mar 25, 2025

Best Western Plus Sikeston
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
The price is $87 per night from Apr 7 to Apr 8
$87
includes taxes & fees
Apr 7 - Apr 8
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,001 reviews)
"Good mattress on beds great night sleep."

Reviewed on Mar 25, 2025

Days Inn and Suites by Wyndham Sikeston
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 out of 5
1240 Commerce Drive, Sikeston, MO
The price is $124 per night from Apr 6 to Apr 7
$124
includes taxes & fees
Apr 6 - Apr 7
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (325 reviews)
Great family stay
"Clean, friendly staff, breakfast had good choices, quiet. Great for family stay."

Reviewed on Mar 23, 2025

Hampton Inn Sikeston
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 out of 5
100 Matthews Lane, Sikeston, MO
The price is $75 per night from Mar 30 to Mar 31
$75
includes taxes & fees
Mar 30 - Mar 31
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (641 reviews)
Great pet friendly clean hotel
"Very very nice stay. Clean room. Efficient staff. Well lit parking lot. Nice grassy area for dogs, Right next to McDonalds and Burger King. Right off highway but quiet.Basic but nice continental breakfast."

Reviewed on Mar 23, 2025

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 out of 5
115 Hospitality Dr, Sikeston, MO
The price is $139 per night from Apr 6 to Apr 7
$139
includes taxes & fees
Apr 6 - Apr 7
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (399 reviews)
"Clean"

Reviewed on Mar 17, 2025

Holiday Inn Express & Suites Sikeston Southwest by IHG
Country Yard Inn and Suite
Country Yard Inn and Suite
2 out of 5
110 South Interstate Drive, Sikeston, MO
The price is $77 per night from Mar 29 to Mar 30
$77
includes taxes & fees
Mar 29 - Mar 30
Stay at this motel in Sikeston. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions The Book Bug and Boot Heel Golf Club are located ...
7/10 Good! (81 reviews)
"It is always brilliant"

Reviewed on Feb 16, 2025

Country Yard Inn and Suite
See all 259 properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.