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Sikeston

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Sikeston Flights as Low as $132

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Sat, Jun 14 - Sat, Jun 21
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$132 Roundtrip, found 4 days ago
$132
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sat, Jun 14 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Jun 21, priced at $132 found 4 days ago
Frontier Airlines
Thu, Jun 19 - Sat, Jun 21
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$141 Roundtrip, found 4 days ago
$141
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Jun 19 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Jun 21, priced at $141 found 4 days ago
Frontier Airlines
Sat, Jun 14 - Sun, Jun 22
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$142 Roundtrip, found 4 days ago
$142
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sat, Jun 14 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sun, Jun 22, priced at $142 found 4 days ago
Frontier Airlines
Thu, Jun 19 - Sun, Jun 22
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$151 Roundtrip, found 4 days ago
$151
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Jun 19 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sun, Jun 22, priced at $151 found 4 days ago
Frontier Airlines
Sun, Jun 15 - Sun, Jun 22
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$153 Roundtrip, found 4 days ago
$153
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sun, Jun 15 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sun, Jun 22, priced at $153 found 4 days ago
Frontier Airlines
Sat, Jun 14 - Thu, Jun 26
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$163 Roundtrip, found 4 days ago
$163
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sat, Jun 14 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Thu, Jun 26, priced at $163 found 4 days ago
Frontier Airlines
Thu, Jun 19 - Thu, Jun 26
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$171 Roundtrip, found 4 days ago
$171
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Jun 19 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Thu, Jun 26, priced at $171 found 4 days ago
Frontier Airlines
Sun, Jun 15 - Thu, Jun 26
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$173 Roundtrip, found 4 days ago
$173
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sun, Jun 15 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Thu, Jun 26, priced at $173 found 4 days ago
Delta
Sat, May 10 - Sun, May 11
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$179 Roundtrip, found 2 days ago
$179
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, May 10 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sun, May 11, priced at $179 found 2 days ago
Frontier Airlines
Sat, May 10 - Sat, May 17
ONT
Los Angeles - Ontario Intl.
STL
Lambert-St. Louis Intl.
$191 Roundtrip, just found
$191
Roundtrip
just found
Select Frontier Airlines flight, departing Sat, May 10 from Los Angeles - Ontario Intl. to Lambert-St. Louis Intl., returning Sat, May 17, priced at $191 just found
Frontier Airlines
Thu, May 1 - Sat, May 3
LAX
Los Angeles Intl.
STL
Lambert-St. Louis Intl.
$198 Roundtrip, found 2 days ago
$198
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, May 1 from Los Angeles Intl. to Lambert-St. Louis Intl., returning Sat, May 3, priced at $198 found 2 days ago
Spirit Airlines
Tue, May 6 - Thu, May 15
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$213 Roundtrip, found 2 days ago
$213
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Tue, May 6 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Thu, May 15, priced at $213 found 2 days ago
American Airlines
Tue, Jun 17 - Tue, Jun 24
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$220 Roundtrip, found 1 day ago
$220
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jun 17 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Jun 24, priced at $220 found 1 day ago
United
Sat, May 10 - Mon, May 12
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$240 Roundtrip, found 2 days ago
$240
Roundtrip
found 2 days ago
Select United flight, departing Sat, May 10 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Mon, May 12, priced at $240 found 2 days ago
Frontier Airlines
Fri, May 9 - Sun, May 11
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$260 Roundtrip, found 1 day ago
$260
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, May 9 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Sun, May 11, priced at $260 found 1 day ago
Alaska Airlines
Tue, May 13 - Fri, May 16
LAX
Los Angeles Intl.
STL
Lambert-St. Louis Intl.
$415 Roundtrip, just found
$415
Roundtrip
just found
Select Alaska Airlines flight, departing Tue, May 13 from Los Angeles Intl. to Lambert-St. Louis Intl., returning Fri, May 16, priced at $415 just found

Cheap Flights to Sikeston

Fall in love at first flight with your vacation to Sikeston by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Sikeston on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Sikeston, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Sikeston

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Sikeston with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Sikeston?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Sikeston are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Sikeston?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Sikeston.

What airport is best to fly into Sikeston?

When you’re planning your trip to Sikeston, convenience is the name of the game. Luckily, Sikeston Cairo Regional Airport is nearby so you can deplane and get going on checking off everything on your Sikeston must-do list.

How much are flights to Sikeston?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Sikeston on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $132, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Sikeston?

The trick to saving a stack of cash on your flight to Sikeston? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $132 right now, why wait?

Sikeston Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$132

Last Minute Hotel Deals in Sikeston

Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
The price is $98 per night from Apr 27 to Apr 28
$98
includes taxes & fees
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,001 reviews)
"Great value stay. Clean hotel with a wonderful, hot breakfast."

Reviewed on Apr 19, 2025

Pear Tree Inn Sikeston
Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
The price is $97 per night from Apr 27 to Apr 28
$97
includes taxes & fees
Apr 27 - Apr 28
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,001 reviews)
"Room had an unsanitary smell. Staff was willing to move me to another room but it had same animal or dirty smell"

Reviewed on Apr 20, 2025

Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
The price is $114 per night from Apr 27 to Apr 28
$114
includes taxes & fees
Apr 27 - Apr 28
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,001 reviews)
"Wonder stay! Excellent hotel."

Reviewed on Apr 13, 2025

Drury Inn & Suites Sikeston, MO
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 out of 5
1240 Commerce Drive, Sikeston, MO
The price is $143 per night from May 4 to May 5
$143
includes taxes & fees
May 4 - May 5
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (332 reviews)
Beautiful but needs some improvement
"Beautiful newer hotel. Comfortable bed and fairly clean but bathroom floor was very sticking from not washing soap off floor when mopping. Also TV had a dark picture and desk person was unable to fix. Also at breakfast the potatoes were not done and there was no batter to make waffles."

Reviewed on Apr 19, 2025

Hampton Inn Sikeston
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
The price is $92 per night from Apr 27 to Apr 28
$92
includes taxes & fees
Apr 27 - Apr 28
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,000 reviews)
"Nice and clean"

Reviewed on Apr 14, 2025

Days Inn and Suites by Wyndham Sikeston
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 out of 5
100 Matthews Lane, Sikeston, MO
The price is $86 per night from Apr 23 to Apr 24
$86
includes taxes & fees
Apr 23 - Apr 24
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (647 reviews)
"Property is always clean, rooms are nice."

Reviewed on Apr 17, 2025

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 out of 5
115 Hospitality Dr, Sikeston, MO
The price is $150 per night from May 18 to May 19
$150
includes taxes & fees
May 18 - May 19
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (402 reviews)
"Nothing"

Reviewed on Apr 11, 2025

Holiday Inn Express & Suites Sikeston Southwest by IHG
Country Yard Inn and Suite
Country Yard Inn and Suite
2 out of 5
110 South Interstate Drive, Sikeston, MO
The price is $77 per night from Apr 23 to Apr 24
$77
includes taxes & fees
Apr 23 - Apr 24
Stay at this motel in Sikeston. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions The Book Bug and Boot Heel Golf Club are located ...
6.8/10 (86 reviews)
"Good but WiFi weak"

Reviewed on Apr 10, 2025

Country Yard Inn and Suite
See all 261 properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.