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Sikeston

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Sikeston Flights as Low as $68

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, Feb 12 - Sat, Feb 15
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$68 Roundtrip, found 14 hours ago
$68
Roundtrip
found 14 hours ago
Select Frontier Airlines flight, departing Wed, Feb 12 from Denver Intl. to Lambert-St. Louis Intl., returning Sat, Feb 15, priced at $68 found 14 hours ago
Frontier Airlines
Mon, Feb 10 - Sat, Feb 15
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$78 Roundtrip, found 16 hours ago
$78
Roundtrip
found 16 hours ago
Select Frontier Airlines flight, departing Mon, Feb 10 from Denver Intl. to Lambert-St. Louis Intl., returning Sat, Feb 15, priced at $78 found 16 hours ago
Frontier Airlines
Fri, Jan 31 - Wed, Feb 5
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$83 Roundtrip, found 3 days ago
$83
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Fri, Jan 31 from Denver Intl. to Lambert-St. Louis Intl., returning Wed, Feb 5, priced at $83 found 3 days ago
Frontier Airlines
Fri, Feb 14 - Sat, Feb 15
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$88 Roundtrip, found 6 days ago
$88
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Fri, Feb 14 from Denver Intl. to Lambert-St. Louis Intl., returning Sat, Feb 15, priced at $88 found 6 days ago
Frontier Airlines
Mon, Feb 10 - Mon, Feb 17
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$93 Roundtrip, found 16 hours ago
$93
Roundtrip
found 16 hours ago
Select Frontier Airlines flight, departing Mon, Feb 10 from Denver Intl. to Lambert-St. Louis Intl., returning Mon, Feb 17, priced at $93 found 16 hours ago
Frontier Airlines
Fri, Feb 14 - Mon, Feb 17
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$100 Roundtrip, found 3 hours ago
$100
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Fri, Feb 14 from Denver Intl. to Lambert-St. Louis Intl., returning Mon, Feb 17, priced at $100 found 3 hours ago
Frontier Airlines
Tue, Feb 25 - Sat, Mar 1
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$119 Roundtrip, found 1 day ago
$119
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Tue, Feb 25 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Sat, Mar 1, priced at $119 found 1 day ago
Frontier Airlines
Fri, Jan 31 - Sat, Feb 1
ORD
O'Hare Intl.
STL
Lambert-St. Louis Intl.
$130 Roundtrip, found 5 days ago
$130
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Fri, Jan 31 from O'Hare Intl. to Lambert-St. Louis Intl., returning Sat, Feb 1, priced at $130 found 5 days ago
Southern Airways Express
Thu, Jun 12 - Sun, Jun 15
ORD
O'Hare Intl.
STL
Lambert-St. Louis Intl.
$140 Roundtrip, found 19 hours ago
$140
Roundtrip
found 19 hours ago
Select Southern Airways Express flight, departing Thu, Jun 12 from O'Hare Intl. to Lambert-St. Louis Intl., returning Sun, Jun 15, priced at $140 found 19 hours ago
United
Wed, Feb 19 - Wed, Feb 26
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$157 Roundtrip, found 6 days ago
$157
Roundtrip
found 6 days ago
Select United flight, departing Wed, Feb 19 from Denver Intl. to Lambert-St. Louis Intl., returning Wed, Feb 26, priced at $157 found 6 days ago
Spirit Airlines
Thu, Feb 20 - Tue, Feb 25
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$189 Roundtrip, found 1 day ago
$189
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Thu, Feb 20 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Tue, Feb 25, priced at $189 found 1 day ago
Delta
Wed, Feb 19 - Wed, Feb 26
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$197 Roundtrip, found 6 days ago
$197
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Feb 19 from Denver Intl. to Lambert-St. Louis Intl., returning Wed, Feb 26, priced at $197 found 6 days ago
American Airlines
Sat, Feb 22 - Mon, Feb 24
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$197 Roundtrip, found 1 day ago
$197
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Feb 22 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Mon, Feb 24, priced at $197 found 1 day ago
Delta
Sat, Feb 22 - Mon, Feb 24
DAL
Love Field
STL
Lambert-St. Louis Intl.
$217 Roundtrip, found 1 day ago
$217
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Feb 22 from Love Field to Lambert-St. Louis Intl., returning Mon, Feb 24, priced at $217 found 1 day ago
Frontier Airlines
Fri, Apr 18 - Wed, Apr 23
ORF
Norfolk Intl.
STL
Lambert-St. Louis Intl.
$231 Roundtrip, found 1 day ago
$231
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Apr 18 from Norfolk Intl. to Lambert-St. Louis Intl., returning Wed, Apr 23, priced at $231 found 1 day ago
Alaska Airlines
Thu, Feb 13 - Sun, Feb 16
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$759 Roundtrip, found 6 days ago
$759
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Thu, Feb 13 from Denver Intl. to Lambert-St. Louis Intl., returning Sun, Feb 16, priced at $759 found 6 days ago

Cheap Flights to Sikeston

Fall in love at first flight with your vacation to Sikeston by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Sikeston on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Sikeston, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Sikeston

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Sikeston with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Sikeston?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Sikeston are in February, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Sikeston?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Sikeston.

What airport is best to fly into Sikeston?

When you’re planning your trip to Sikeston, convenience is the name of the game. Luckily, Sikeston Cairo Regional Airport is nearby so you can deplane and get going on checking off everything on your Sikeston must-do list.

How much are flights to Sikeston?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Sikeston on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $68, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Sikeston?

The trick to saving a stack of cash on your flight to Sikeston? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $68 right now, why wait?

Sikeston Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$120

Last Minute Hotel Deals in Sikeston

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
The price is $72 per night from Jan 26 to Jan 27
$72
includes taxes & fees
Jan 26 - Jan 27
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,001 reviews)
"Quick trip. Just needed a stopover. Comfy beds clean room"

Reviewed on Jan 13, 2025

Days Inn and Suites by Wyndham Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
The price is $114 per night from Jan 31 to Feb 1
$114
includes taxes & fees
Jan 31 - Feb 1
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,002 reviews)
"They were very nice and clean"

Reviewed on Jan 20, 2025

Drury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
The price is $88 per night from Jan 31 to Feb 1
$88
includes taxes & fees
Jan 31 - Feb 1
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,001 reviews)
"Wonderful"

Reviewed on Jan 21, 2025

Pear Tree Inn Sikeston
Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
The price is $97 per night from Jan 26 to Jan 27
$97
includes taxes & fees
Jan 26 - Jan 27
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,000 reviews)
"Good place to stay, should add fried egg to their breakfast menu to make it excellent."

Reviewed on Jan 5, 2025

Best Western Plus Sikeston
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 out of 5
100 Matthews Lane, Sikeston, MO
The price is $73 per night from Jan 26 to Jan 27
$73
includes taxes & fees
Jan 26 - Jan 27
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (621 reviews)
"Basic hotel, clean, friendly, looking like recently did some updating"

Reviewed on Jan 22, 2025

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
2.5 out of 5
115 Hospitality Dr, Sikeston, MO
The price is $128 per night from Feb 9 to Feb 10
$128
includes taxes & fees
Feb 9 - Feb 10
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (389 reviews)
"Great"

Reviewed on Jan 6, 2025

Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 out of 5
1240 Commerce Drive, Sikeston, MO
The price is $131 per night from Feb 9 to Feb 10
$131
includes taxes & fees
Feb 9 - Feb 10
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (313 reviews)
"Nice stay the breakfast was great"

Reviewed on Jan 3, 2025

Hampton Inn Sikeston
Country Yard Inn and Suite
Country Yard Inn and Suite
2 out of 5
110 South Interstate Drive, Sikeston, MO
The price is $70 per night from Jan 24 to Jan 25
$70
includes taxes & fees
Jan 24 - Jan 25
Stay at this motel in Sikeston. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions The Book Bug and Boot Heel Golf Club are located ...
7.2/10 Good! (67 reviews)
Clean stay for reasonable cost
"Nice and clean place to stay for a reasonable cost."

Reviewed on Dec 19, 2024

Country Yard Inn and Suite
See all 247 properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.