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Sikeston

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Sikeston Flights as Low as $90

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Thu, Aug 21 - Thu, Aug 28
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$90 Roundtrip, found 1 day ago
$90
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Aug 21 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Thu, Aug 28, priced at $90 found 1 day ago
Frontier Airlines
Thu, Aug 21 - Mon, Aug 25
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$104 Roundtrip, found 19 hours ago
$104
Roundtrip
found 19 hours ago
Select Frontier Airlines flight, departing Thu, Aug 21 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Mon, Aug 25, priced at $104 found 19 hours ago
Frontier Airlines
Thu, Aug 21 - Sun, Aug 31
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$110 Roundtrip, found 13 hours ago
$110
Roundtrip
found 13 hours ago
Select Frontier Airlines flight, departing Thu, Aug 21 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Sun, Aug 31, priced at $110 found 13 hours ago
Frontier Airlines
Sat, Oct 4 - Sat, Oct 11
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$129 Roundtrip, found 15 hours ago
$129
Roundtrip
found 15 hours ago
Select Frontier Airlines flight, departing Sat, Oct 4 from Denver Intl. to Lambert-St. Louis Intl., returning Sat, Oct 11, priced at $129 found 15 hours ago
United
Sat, Oct 4 - Sat, Oct 11
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$133 Roundtrip, found 15 hours ago
$133
Roundtrip
found 15 hours ago
Select United flight, departing Sat, Oct 4 from Denver Intl. to Lambert-St. Louis Intl., returning Sat, Oct 11, priced at $133 found 15 hours ago
American Airlines
Sat, Oct 4 - Sat, Oct 11
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$159 Roundtrip, found 15 hours ago
$159
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Sat, Oct 4 from Denver Intl. to Lambert-St. Louis Intl., returning Sat, Oct 11, priced at $159 found 15 hours ago
Spirit Airlines
Thu, Aug 21 - Mon, Aug 25
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$182 Roundtrip, found 19 hours ago
$182
Roundtrip
found 19 hours ago
Select Spirit Airlines flight, departing Thu, Aug 21 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Mon, Aug 25, priced at $182 found 19 hours ago
Delta
Tue, Aug 26 - Tue, Aug 26
DAL
Love Field
STL
Lambert-St. Louis Intl.
$194 Roundtrip, found 3 hours ago
$194
Roundtrip
found 3 hours ago
Select Delta flight, departing Tue, Aug 26 from Love Field to Lambert-St. Louis Intl., returning Tue, Aug 26, priced at $194 found 3 hours ago
Delta
Tue, Aug 26 - Tue, Aug 26
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$194 Roundtrip, found 4 hours ago
$194
Roundtrip
found 4 hours ago
Select Delta flight, departing Tue, Aug 26 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Tue, Aug 26, priced at $194 found 4 hours ago
United
Sat, Oct 25 - Mon, Oct 27
LAX
Los Angeles Intl.
STL
Lambert-St. Louis Intl.
$207 Roundtrip, found 9 hours ago
$207
Roundtrip
found 9 hours ago
Select United flight, departing Sat, Oct 25 from Los Angeles Intl. to Lambert-St. Louis Intl., returning Mon, Oct 27, priced at $207 found 9 hours ago
Alaska Airlines
Thu, Oct 23 - Mon, Oct 27
LAX
Los Angeles Intl.
STL
Lambert-St. Louis Intl.
$259 Roundtrip, found 18 hours ago
$259
Roundtrip
found 18 hours ago
Select Alaska Airlines flight, departing Thu, Oct 23 from Los Angeles Intl. to Lambert-St. Louis Intl., returning Mon, Oct 27, priced at $259 found 18 hours ago
Frontier Airlines
Fri, Oct 24 - Sat, Oct 25
ONT
Los Angeles - Ontario Intl.
STL
Lambert-St. Louis Intl.
$302 Roundtrip, found 3 days ago
$302
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Fri, Oct 24 from Los Angeles - Ontario Intl. to Lambert-St. Louis Intl., returning Sat, Oct 25, priced at $302 found 3 days ago
American Airlines
Wed, Aug 20 - Fri, Aug 22
DEN
Denver Intl.
PAH
Barkley Regional
$313 Roundtrip, found 15 hours ago
$313
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Wed, Aug 20 from Denver Intl. to Barkley Regional, returning Fri, Aug 22, priced at $313 found 15 hours ago
American Airlines
Wed, Aug 20 - Wed, Aug 27
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$403 Roundtrip, found 1 day ago
$403
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Aug 20 from Dallas-Fort Worth Intl. to Barkley Regional, returning Wed, Aug 27, priced at $403 found 1 day ago
United
Wed, Sep 24 - Tue, Sep 30
ONT
Los Angeles - Ontario Intl.
PAH
Barkley Regional
$557 Roundtrip, found 6 days ago
$557
Roundtrip
found 6 days ago
Select United flight, departing Wed, Sep 24 from Los Angeles - Ontario Intl. to Barkley Regional, returning Tue, Sep 30, priced at $557 found 6 days ago
American Airlines
Sat, Jul 12 - Tue, Jul 15
LAX
Los Angeles Intl.
PAH
Barkley Regional
$845 Roundtrip, found 19 hours ago
$845
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Sat, Jul 12 from Los Angeles Intl. to Barkley Regional, returning Tue, Jul 15, priced at $845 found 19 hours ago

Cheap Flights to Sikeston

Fall in love at first flight with your vacation to Sikeston by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Sikeston on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Sikeston, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Sikeston

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Sikeston with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Sikeston?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Sikeston are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Sikeston?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Sikeston.

What airport is best to fly into Sikeston?

When you’re planning your trip to Sikeston, convenience is the name of the game. Luckily, Sikeston Cairo Regional Airport is nearby so you can deplane and get going on checking off everything on your Sikeston must-do list.

How much are flights to Sikeston?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Sikeston on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $90, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Sikeston?

The trick to saving a stack of cash on your flight to Sikeston? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $90 right now, why wait?

Sikeston Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$89

Last Minute Hotel Deals in Sikeston

Best Western Plus Sikeston
Best Western Plus Sikeston
2.5 out of 5
120 S Interstate Drive, Sikeston, MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,003 reviews)
"Didn’t have to think about anything. It was all right."

Reviewed on Jul 3, 2025

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Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,004 reviews)
"This is a great place to stay! Very clean, comfortable beds, free breakfast and supper. The people were very nice and I can’t recommend it highly enough!"

Reviewed on Jul 6, 2025

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Drury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston
2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,003 reviews)
"Very clean room and pool and good breakfast!"

Reviewed on Jun 30, 2025

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Pear Tree Inn Sikeston
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 out of 5
1240 Commerce Drive, Sikeston, MO
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (360 reviews)
"Stayed here with my two kids and had a great experience! We didn’t get a chance to use the pool, but we saw a lot of happy guests coming out of it, so it definitely looked like a hit. The breakfast was excellent—lots of variety and everything was fresh. The hotel was clean and well-kept. Overall, ..."

Reviewed on Jun 28, 2025

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Hampton Inn Sikeston
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2 out of 5
220 S Interstate Dr, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,001 reviews)
Keep up the renovations
"This hotel looked like an old apartment building renovation into a hotel with much wrk in progress. Decent stay. Spacious. Very minimal breakfast offerings. The geese outside sure left messes everywhere but the greeting cat was a nice touch"

Reviewed on Jun 28, 2025

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Days Inn and Suites by Wyndham Sikeston
Fairfield by Marriott Inn & Suites Sikeston
Fairfield by Marriott Inn & Suites Sikeston
2.5 out of 5
1239 Commerce Drive, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
9.8/10 Exceptional! (10 reviews)
"Clean and comfortable"

Reviewed on Jun 25, 2025

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Fairfield by Marriott Inn & Suites Sikeston
Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55
2.5 out of 5
109 Matthews Ln, Sikeston, MO
Book a stay at this business-friendly hotel in Sikeston. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (266 reviews)
"It was cool"

Reviewed on Jun 24, 2025

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Comfort Inn & Suites Sikeston I-55
Country Yard Inn and Suite
Country Yard Inn and Suite
2 out of 5
110 South Interstate Drive, Sikeston, MO
Stay at this motel in Sikeston. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Central Park and Sikeston Depot Museum are located ...
7/10 Good! (96 reviews)
"Good but WiFi weak"

Reviewed on Apr 10, 2025

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Country Yard Inn and Suite
See all 261 properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.