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Featured Cape Girardeau Family Hotels
Drury Inn & Suites Cape Girardeau
3303 Campster Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street, Cape Girardeau, MO
Fully refundable
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
Hampton Inn Cape Girardeau I 55 East
207 S Mt Auburn Rd, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd, Cape Girardeau, MO
Fully refundable
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
Quality Inn
2011 North Kingshighway, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels with Pools in Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street, Cape Girardeau, MO
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,010 reviews)
"Easy walking distance to dining areas"
Reviewed on Mar 9, 2025
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau, MO
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,003 reviews)
"The front desk staff was excellent!!..very friendly & helpful!..will definitely stay again!"
Reviewed on Feb 25, 2025
Drury Inn & Suites Cape Girardeau
3303 Campster Drive, Cape Girardeau, MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (906 reviews)
"Very nice motel, we loved our stay"
Reviewed on Mar 6, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels With Connecting Rooms in Cape Girardeau
Drury Inn & Suites Cape Girardeau
3303 Campster Drive, Cape Girardeau, MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street, Cape Girardeau, MO
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau, MO
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options
- Hotels with Free Parking in Cape Girardeau
- Hotels with a Pool in Cape Girardeau
- Casinos in Cape Girardeau
- Pet-friendly Hotels in Cape Girardeau
- Hotels with an Indoor Pool in Cape Girardeau
- Hotels with Hot Tubs in Cape Girardeau
- Hotel Wedding Venues in Cape Girardeau
- Apartment Hotel in Cape Girardeau
- Luxury Hotels in Cape Girardeau
- Resorts & Hotels with Spas in Cape Girardeau
Top Points of Interests in Cape Girardeau
- Hotels near Southeast Missouri State University
- Hotels near Isle Casino Cape Girardeau
- Hotels near Riverfront Bridge Park
- Hotels near Riverfront Park
- Hotels near Cape Rock Park
- Hotels near Hunter Valley Winery
- Hotels near Cape Girardeau Conservation Nature Center
- Hotels near Lazy L Safari Park
- Hotels near Cape Splash Family Aquatic Center
- Hotels near eDen Spa & Salon
- Hotels near Fort D Historic Site
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Giant City State Park
- Hotels near Trail of Tears State Park
- Hotels near Stone Creek Golf Club and Resort
- Hotels near StarView Vineyards
- Hotels near Pomona Winery
- Hotels near Bollinger Mill State Historic Site
Cities near Cape Girardeau
- Carbondale Hotels (33.45 mi)
- Sikeston Hotels (29.82 mi)
- Ozarks Hotels (163.98 mi)
- Southern Illinois Hotels (85.27 mi)
- Central United States Hotels (256.31 mi)
- Jackson Hotels (9.69 mi)
- Anna Hotels (18.3 mi)
- Perryville Hotels (34.87 mi)
- Makanda Hotels (27.39 mi)
- Murphysboro Hotels (33.6 mi)
- Cobden Hotels (21.29 mi)
- Alto Pass Hotels (21.31 mi)
- Charleston Hotels (28 mi)
- Buncombe Hotels (31.81 mi)
- Southeast Missouri Hotels (50.24 mi)
- Pomona Hotels (24.37 mi)
- Cairo Hotels (28 mi)
- Jonesboro Hotels (17.02 mi)
- Marble Hill Hotels (25.49 mi)
- Dongola Hotels (19.71 mi)
Car Rentals Near Cape Girardeau
- Car rentals in Carbondale
- Car rentals in Sikeston
- Car rentals in Ozarks
- Car rentals in Southern Illinois
- Car rentals in Central United States
- Car rentals in Jackson
- Car rentals in Anna
- Car rentals in Perryville
- Car rentals in Makanda
- Car rentals in Murphysboro
- Car rentals in Cobden
- Car rentals in Alto Pass
- Car rentals in Charleston
- Car rentals in Buncombe
- Car rentals in Southeast Missouri
- Car rentals in Pomona
Top Family Hotel Destinations
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- Ocean City Family Hotels
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- Reno Family Hotels
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- Phoenix Family Hotels
- Niagara Falls Family Hotels
- New York Family Hotels
- Whistler Family Hotels
- Houston Family Hotels
- Fort Walton Beach Family Hotels
- Pensacola Beach Family Hotels
- Tampa Family Hotels
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Top Booked Hotels in Cape Girardeau
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