Search Cheap Flights to
Cape Girardeau

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Cape Girardeau Flights as Low as $428

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Mon, Jun 16 - Fri, Jun 20
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$428 Roundtrip, found 2 days ago
$428
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Jun 16 from Los Angeles Intl. to Cape Girardeau Municipal, returning Fri, Jun 20, priced at $428 found 2 days ago
American Airlines
Mon, Jun 16 - Fri, Jun 20
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$472 Roundtrip, found 2 days ago
$472
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Jun 16 from Los Angeles Intl. to Cape Girardeau Municipal, returning Fri, Jun 20, priced at $472 found 2 days ago
American Airlines
Mon, Jun 16 - Fri, Jun 20
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$478 Roundtrip, found 12 hours ago
$478
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Mon, Jun 16 from Los Angeles Intl. to Cape Girardeau Municipal, returning Fri, Jun 20, priced at $478 found 12 hours ago
American Airlines
Mon, Jun 16 - Fri, Jun 20
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$484 Roundtrip, found 2 days ago
$484
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Jun 16 from Los Angeles Intl. to Cape Girardeau Municipal, returning Fri, Jun 20, priced at $484 found 2 days ago
American Airlines
Mon, Jun 16 - Sat, Jun 21
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$487 Roundtrip, found 1 day ago
$487
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Jun 16 from Los Angeles Intl. to Cape Girardeau Municipal, returning Sat, Jun 21, priced at $487 found 1 day ago
American Airlines
Mon, Jun 16 - Fri, Jun 20
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$488 Roundtrip, just found
$488
Roundtrip
just found
Select American Airlines flight, departing Mon, Jun 16 from Los Angeles Intl. to Cape Girardeau Municipal, returning Fri, Jun 20, priced at $488 just found
American Airlines
Mon, Jun 16 - Fri, Jun 20
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$496 Roundtrip, found 2 days ago
$496
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Jun 16 from Los Angeles Intl. to Cape Girardeau Municipal, returning Fri, Jun 20, priced at $496 found 2 days ago
American Airlines
Tue, Jun 10 - Wed, Jun 18
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$498 Roundtrip, found 17 hours ago
$498
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Tue, Jun 10 from Los Angeles Intl. to Cape Girardeau Municipal, returning Wed, Jun 18, priced at $498 found 17 hours ago
American Airlines
Mon, Jun 16 - Fri, Jun 20
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$502 Roundtrip, found 2 days ago
$502
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Jun 16 from Los Angeles Intl. to Cape Girardeau Municipal, returning Fri, Jun 20, priced at $502 found 2 days ago
American Airlines
Mon, Jun 16 - Fri, Jun 20
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$508 Roundtrip, found 12 hours ago
$508
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Mon, Jun 16 from Los Angeles Intl. to Cape Girardeau Municipal, returning Fri, Jun 20, priced at $508 found 12 hours ago
American Airlines
Mon, Jun 16 - Fri, Jun 20
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$508 Roundtrip, just found
$508
Roundtrip
just found
Select American Airlines flight, departing Mon, Jun 16 from Los Angeles Intl. to Cape Girardeau Municipal, returning Fri, Jun 20, priced at $508 just found
American Airlines
Mon, Jun 16 - Fri, Jun 20
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$512 Roundtrip, found 1 day ago
$512
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Jun 16 from Los Angeles Intl. to Cape Girardeau Municipal, returning Fri, Jun 20, priced at $512 found 1 day ago
American Airlines
Mon, Jun 16 - Fri, Jun 20
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$513 Roundtrip, found 11 hours ago
$513
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Mon, Jun 16 from Los Angeles Intl. to Cape Girardeau Municipal, returning Fri, Jun 20, priced at $513 found 11 hours ago
American Airlines
Mon, Jun 16 - Fri, Jun 20
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$518 Roundtrip, just found
$518
Roundtrip
just found
Select American Airlines flight, departing Mon, Jun 16 from Los Angeles Intl. to Cape Girardeau Municipal, returning Fri, Jun 20, priced at $518 just found
American Airlines
Mon, Jun 16 - Fri, Jun 20
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$522 Roundtrip, found 12 hours ago
$522
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Mon, Jun 16 from Los Angeles Intl. to Cape Girardeau Municipal, returning Fri, Jun 20, priced at $522 found 12 hours ago
American Airlines
Sat, May 31 - Wed, Jun 4
FLO
Florence Regional
CGI
Cape Girardeau Municipal
$715 Roundtrip, found 4 days ago
$715
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, May 31 from Florence Regional to Cape Girardeau Municipal, returning Wed, Jun 4, priced at $715 found 4 days ago

Cheap Flights to Cape Girardeau

Fall in love at first flight with your vacation to Cape Girardeau by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Cape Girardeau on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Cape Girardeau, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Cape Girardeau

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Cape Girardeau with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MDH airport.

What is the cheapest month to fly to Cape Girardeau?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Cape Girardeau are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Cape Girardeau?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Cape Girardeau.

What airport is best to fly into Cape Girardeau?

When you’re planning your trip to Cape Girardeau, convenience is the name of the game. Luckily, Cape Girardeau Cape Girardeau Municipal Airport is nearby so you can deplane and get going on checking off everything on your Cape Girardeau must-do list.

How much are flights to Cape Girardeau?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Cape Girardeau on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $428, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Cape Girardeau?

The trick to saving a stack of cash on your flight to Cape Girardeau? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $428 right now, why wait?

Cape Girardeau Flight Information
Destination airport
Cape Girardeau Municipal
Destination airport IATA code
CGI
Roundtrip price
$428

Last Minute Hotel Deals in Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,003 reviews)
"Very nice, clean hotel. The breakfast was also very good!"

Reviewed on May 22, 2025

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Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview
The Riverview
2 out of 5
777 Main St, Cape Girardeau, MO
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront Park are ...
9.2/10 Wonderful! (272 reviews)
"The hotel was clean and beautiful"

Reviewed on May 27, 2025

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The Riverview
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 out of 5
3253 William Street, Cape Girardeau, MO
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,001 reviews)
"The beds were comfortable and the room was clean. The breakfast was cold and not very good."

Reviewed on May 20, 2025

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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (794 reviews)
"The gym conference room and games my basketball team enjoyed the stay service was excellent also"

Reviewed on May 26, 2025

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Candlewood Suites Cape Girardeau by IHG
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,002 reviews)
"everything was so great from check in , to breakfast and checking out"

Reviewed on May 21, 2025

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Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,000 reviews)
"Very clean and staff was friendly"

Reviewed on May 25, 2025

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Pear Tree Inn Cape Girardeau West
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3 out of 5
3303 Campster Drive, Cape Girardeau, MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (929 reviews)
"It was quiet and clean."

Reviewed on May 19, 2025

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Drury Inn & Suites Cape Girardeau
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
3 out of 5
400 Broadway St., Cape Girardeau, MO
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
9.4/10 Exceptional! (414 reviews)
Overall great stay!
"Overall we had a great stay here for just a night in town for a soccer tournament. I had filtered out hotels that had a pool and somehow this one slipped through but it does not have a pool. I also filtered by hotels that included free breakfast, this hotel has a restaurant but breakfast is not free. ..."

Reviewed on May 19, 2025

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Courtyard by Marriott Cape Girardeau Downtown
See all 162 properties in Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.