Search Cheap Flights to
Cape Girardeau

Photo by Skyy

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Cape Girardeau Flights as Low as $440

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Mon, Jun 16 - Sat, Jun 21
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$440 Roundtrip, found 1 day ago
$440
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Jun 16 from Los Angeles Intl. to Cape Girardeau Municipal, returning Sat, Jun 21, priced at $440 found 1 day ago
American Airlines
Tue, Jun 17 - Sat, Jun 21
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$443 Roundtrip, found 1 day ago
$443
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jun 17 from Los Angeles Intl. to Cape Girardeau Municipal, returning Sat, Jun 21, priced at $443 found 1 day ago
American Airlines
Sat, Jun 14 - Sat, Jun 21
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$445 Roundtrip, found 1 day ago
$445
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Jun 14 from Los Angeles Intl. to Cape Girardeau Municipal, returning Sat, Jun 21, priced at $445 found 1 day ago
American Airlines
Mon, Jun 16 - Thu, Jun 19
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$446 Roundtrip, found 1 day ago
$446
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Jun 16 from Los Angeles Intl. to Cape Girardeau Municipal, returning Thu, Jun 19, priced at $446 found 1 day ago
American Airlines
Tue, Jun 17 - Thu, Jun 19
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$449 Roundtrip, found 1 day ago
$449
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jun 17 from Los Angeles Intl. to Cape Girardeau Municipal, returning Thu, Jun 19, priced at $449 found 1 day ago
American Airlines
Mon, Jun 16 - Fri, Jun 20
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$460 Roundtrip, found 1 day ago
$460
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Jun 16 from Los Angeles Intl. to Cape Girardeau Municipal, returning Fri, Jun 20, priced at $460 found 1 day ago
American Airlines
Sat, Jun 14 - Sat, Jun 21
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$463 Roundtrip, found 1 day ago
$463
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Jun 14 from Los Angeles Intl. to Cape Girardeau Municipal, returning Sat, Jun 21, priced at $463 found 1 day ago
American Airlines
Sat, Jun 14 - Sat, Jun 21
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$464 Roundtrip, found 1 day ago
$464
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Jun 14 from Los Angeles Intl. to Cape Girardeau Municipal, returning Sat, Jun 21, priced at $464 found 1 day ago
American Airlines
Sat, Jun 14 - Thu, Jun 19
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$469 Roundtrip, found 1 day ago
$469
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Jun 14 from Los Angeles Intl. to Cape Girardeau Municipal, returning Thu, Jun 19, priced at $469 found 1 day ago
American Airlines
Sun, Jun 15 - Sat, Jun 21
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$474 Roundtrip, found 1 day ago
$474
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Jun 15 from Los Angeles Intl. to Cape Girardeau Municipal, returning Sat, Jun 21, priced at $474 found 1 day ago
American Airlines
Sun, Jun 15 - Thu, Jun 19
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$480 Roundtrip, found 1 day ago
$480
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Jun 15 from Los Angeles Intl. to Cape Girardeau Municipal, returning Thu, Jun 19, priced at $480 found 1 day ago
American Airlines
Sat, Jun 14 - Fri, Jun 20
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$483 Roundtrip, found 1 day ago
$483
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Jun 14 from Los Angeles Intl. to Cape Girardeau Municipal, returning Fri, Jun 20, priced at $483 found 1 day ago
American Airlines
Sat, Jun 14 - Sat, Jun 21
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$485 Roundtrip, found 1 day ago
$485
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Jun 14 from Los Angeles Intl. to Cape Girardeau Municipal, returning Sat, Jun 21, priced at $485 found 1 day ago
American Airlines
Thu, Jun 12 - Thu, Jun 19
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$489 Roundtrip, found 1 day ago
$489
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Jun 12 from Los Angeles Intl. to Cape Girardeau Municipal, returning Thu, Jun 19, priced at $489 found 1 day ago
American Airlines
Sat, Jun 14 - Sat, Jun 21
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$494 Roundtrip, found 1 day ago
$494
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Jun 14 from Los Angeles Intl. to Cape Girardeau Municipal, returning Sat, Jun 21, priced at $494 found 1 day ago
American Airlines
Thu, Jun 12 - Fri, Jun 20
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$504 Roundtrip, found 1 day ago
$504
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Jun 12 from Los Angeles Intl. to Cape Girardeau Municipal, returning Fri, Jun 20, priced at $504 found 1 day ago

Cheap Flights to Cape Girardeau

Fall in love at first flight with your vacation to Cape Girardeau by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Cape Girardeau on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Cape Girardeau, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Cape Girardeau

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Cape Girardeau with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MDH airport.

What is the cheapest month to fly to Cape Girardeau?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Cape Girardeau are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Cape Girardeau?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Cape Girardeau.

What airport is best to fly into Cape Girardeau?

When you’re planning your trip to Cape Girardeau, convenience is the name of the game. Luckily, Cape Girardeau Cape Girardeau Municipal Airport is nearby so you can deplane and get going on checking off everything on your Cape Girardeau must-do list.

How much are flights to Cape Girardeau?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Cape Girardeau on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $440, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Cape Girardeau?

The trick to saving a stack of cash on your flight to Cape Girardeau? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $440 right now, why wait?

Cape Girardeau Flight Information
Destination airport
Cape Girardeau Municipal
Destination airport IATA code
CGI
Roundtrip price
$440

Last Minute Hotel Deals in Cape Girardeau

The Riverview
The Riverview
3.5 out of 5
777 Main St, Cape Girardeau, MO
The price is $121 per night from May 11 to May 12
$121
includes taxes & fees
May 11 - May 12
Stay at this 3.5-star hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront ...
9.2/10 Wonderful! (246 reviews)
"Wonderful stay"

Reviewed on May 1, 2025

The Riverview
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
The price is $102 per night from May 11 to May 12
$102
includes taxes & fees
May 11 - May 12
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,009 reviews)
"The rooms were nice beds were comfy"

Reviewed on May 2, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 out of 5
3253 William Street, Cape Girardeau, MO
The price is $112 per night from May 11 to May 12
$112
includes taxes & fees
May 11 - May 12
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,001 reviews)
Return Stay💋
"I chose this hotel because I stayed 8 months ago when I daughter was scheduled for a C-section and I was so happy with the staff, location of the property and condition of the room I had to return."

Reviewed on Apr 25, 2025

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
The price is $98 per night from May 18 to May 19
$98
includes taxes & fees
May 18 - May 19
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (776 reviews)
"Was clean and comfortable"

Reviewed on May 1, 2025

Candlewood Suites Cape Girardeau by IHG
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
The price is $66 per night from May 11 to May 12
$66
includes taxes & fees
May 11 - May 12
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,001 reviews)
"Stage was very helpful"

Reviewed on May 1, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3 out of 5
3303 Campster Drive, Cape Girardeau, MO
The price is $107 per night from Jun 1 to Jun 2
$107
includes taxes & fees
Jun 1 - Jun 2
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (924 reviews)
"Always The best hotel"

Reviewed on Apr 27, 2025

Drury Inn & Suites Cape Girardeau
Quality Inn
Quality Inn
2.5 out of 5
2011 North Kingshighway, Cape Girardeau, MO
The price is $75 per night from May 11 to May 12
$75
includes taxes & fees
May 11 - May 12
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7/10 Good! (571 reviews)
Best Hotel in Cape!!
"My husband and I like to get away sometimes on the weekend and a lot more than not we prefer Quality Inn over others, it is affordable; good location; rooms are nice and cozy, I would like to maybe request a little more hot breakfast."

Reviewed on Apr 26, 2025

Quality Inn
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
The price is $81 per night from May 11 to May 12
$81
includes taxes & fees
May 11 - May 12
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,001 reviews)
Pear Tree Inn West
"Very friendly staff. Very clean, comfortable, and economical property. It was close to the interstate for easy access, but very quiet inside the room. I would certainly stay at this property again and highly recommend it."

Reviewed on Apr 30, 2025

Pear Tree Inn Cape Girardeau West
See all 158 properties in Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.