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Cape Girardeau

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Cape Girardeau Flights as Low as $642

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Fri, Jun 20 - Thu, Jun 26
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$642 Roundtrip, found 6 days ago
$642
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Jun 20 from Los Angeles Intl. to Cape Girardeau Municipal, returning Thu, Jun 26, priced at $642 found 6 days ago
American Airlines
Tue, Jun 24 - Wed, Jun 25
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$684 Roundtrip, found 18 hours ago
$684
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Tue, Jun 24 from Los Angeles Intl. to Cape Girardeau Municipal, returning Wed, Jun 25, priced at $684 found 18 hours ago
American Airlines
Tue, Jun 24 - Wed, Jun 25
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$694 Roundtrip, found 18 hours ago
$694
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Tue, Jun 24 from Los Angeles Intl. to Cape Girardeau Municipal, returning Wed, Jun 25, priced at $694 found 18 hours ago
American Airlines
Tue, Jun 24 - Thu, Jun 26
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$704 Roundtrip, found 1 day ago
$704
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jun 24 from Los Angeles Intl. to Cape Girardeau Municipal, returning Thu, Jun 26, priced at $704 found 1 day ago
American Airlines
Tue, Jun 24 - Wed, Jun 25
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$714 Roundtrip, found 18 hours ago
$714
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Tue, Jun 24 from Los Angeles Intl. to Cape Girardeau Municipal, returning Wed, Jun 25, priced at $714 found 18 hours ago
American Airlines
Tue, Jun 24 - Sat, Jun 28
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$725 Roundtrip, found 3 days ago
$725
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Jun 24 from Los Angeles Intl. to Cape Girardeau Municipal, returning Sat, Jun 28, priced at $725 found 3 days ago
American Airlines
Tue, Jun 24 - Thu, Jun 26
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$744 Roundtrip, found 1 day ago
$744
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jun 24 from Los Angeles Intl. to Cape Girardeau Municipal, returning Thu, Jun 26, priced at $744 found 1 day ago
American Airlines
Mon, Jun 23 - Sat, Jun 28
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$745 Roundtrip, found 3 days ago
$745
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Jun 23 from Los Angeles Intl. to Cape Girardeau Municipal, returning Sat, Jun 28, priced at $745 found 3 days ago
American Airlines
Tue, Jun 24 - Thu, Jun 26
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$753 Roundtrip, found 1 day ago
$753
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jun 24 from Los Angeles Intl. to Cape Girardeau Municipal, returning Thu, Jun 26, priced at $753 found 1 day ago
American Airlines
Tue, Jun 24 - Wed, Jun 25
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$769 Roundtrip, found 3 days ago
$769
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Jun 24 from Los Angeles Intl. to Cape Girardeau Municipal, returning Wed, Jun 25, priced at $769 found 3 days ago
American Airlines
Tue, Jun 24 - Wed, Jun 25
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$780 Roundtrip, found 18 hours ago
$780
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Tue, Jun 24 from Los Angeles Intl. to Cape Girardeau Municipal, returning Wed, Jun 25, priced at $780 found 18 hours ago
American Airlines
Tue, Jun 24 - Thu, Jun 26
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$789 Roundtrip, found 3 days ago
$789
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Jun 24 from Los Angeles Intl. to Cape Girardeau Municipal, returning Thu, Jun 26, priced at $789 found 3 days ago
American Airlines
Tue, Jun 24 - Thu, Jun 26
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$800 Roundtrip, found 1 day ago
$800
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jun 24 from Los Angeles Intl. to Cape Girardeau Municipal, returning Thu, Jun 26, priced at $800 found 1 day ago
American Airlines
Mon, Jun 23 - Thu, Jun 26
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$809 Roundtrip, found 3 days ago
$809
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Jun 23 from Los Angeles Intl. to Cape Girardeau Municipal, returning Thu, Jun 26, priced at $809 found 3 days ago
American Airlines
Tue, Jun 24 - Wed, Jun 25
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$810 Roundtrip, found 18 hours ago
$810
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Tue, Jun 24 from Los Angeles Intl. to Cape Girardeau Municipal, returning Wed, Jun 25, priced at $810 found 18 hours ago
American Airlines
Mon, Jun 23 - Mon, Jun 23
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$829 Roundtrip, found 3 days ago
$829
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Jun 23 from Los Angeles Intl. to Cape Girardeau Municipal, returning Mon, Jun 23, priced at $829 found 3 days ago

Cheap Flights to Cape Girardeau

Fall in love at first flight with your vacation to Cape Girardeau by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Cape Girardeau on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Cape Girardeau, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Cape Girardeau

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Cape Girardeau with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MDH airport.

What is the cheapest month to fly to Cape Girardeau?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Cape Girardeau are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Cape Girardeau?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Cape Girardeau.

What airport is best to fly into Cape Girardeau?

When you’re planning your trip to Cape Girardeau, convenience is the name of the game. Luckily, Cape Girardeau Cape Girardeau Municipal Airport is nearby so you can deplane and get going on checking off everything on your Cape Girardeau must-do list.

How much are flights to Cape Girardeau?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Cape Girardeau on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $642, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Cape Girardeau?

The trick to saving a stack of cash on your flight to Cape Girardeau? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $642 right now, why wait?

Cape Girardeau Flight Information
Destination airport
Cape Girardeau Municipal
Destination airport IATA code
CGI
Roundtrip price
$642

Last Minute Hotel Deals in Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,005 reviews)
Excellent seevice
"The staff was amazing! Always smiling!!"

Reviewed on Jun 16, 2025

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Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview
The Riverview
2 out of 5
777 Main St, Cape Girardeau, MO
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront Park are ...
9.2/10 Wonderful! (299 reviews)
"Great property. I wasn’t there long, but it was clean and comfortable."

Reviewed on Jun 15, 2025

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The Riverview
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 out of 5
3253 William Street, Cape Girardeau, MO
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,001 reviews)
"Nice hotel"

Reviewed on Jun 15, 2025

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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (803 reviews)
Nice Stay
"The stay was amazing and I loved the set-up. The only issue I had was the bed seemed to have been broke on one side but everything else was nice"

Reviewed on Jun 5, 2025

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Candlewood Suites Cape Girardeau by IHG
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,000 reviews)
"I like the location and convenience of being right off the hwy. It is worth the price!"

Reviewed on Jun 13, 2025

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Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,005 reviews)
"The location was good and many options for dining, close to the highway but parking was very limited. The room appeared clean but I did find a used soap bar in the shower, so that means the shower wasn't cleaned from the last person who stayed. The staff were so friendly and welcoming. I appreciated ..."

Reviewed on Jun 16, 2025

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Pear Tree Inn Cape Girardeau Near the Medical Center
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
3 out of 5
400 Broadway St., Cape Girardeau, MO
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
9.4/10 Exceptional! (419 reviews)
"Great hotel!!!"

Reviewed on Jun 13, 2025

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Courtyard by Marriott Cape Girardeau Downtown
Quality Inn
Quality Inn
2.5 out of 5
2011 North Kingshighway, Cape Girardeau, MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7/10 Good! (593 reviews)
"Stayed one night. Was a quiet stay. Pool was clean. Room was clean and comfortable."

Reviewed on Jun 15, 2025

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Quality Inn
See all 162 properties in Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.