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Choose from 251 Jackson Hotel Deals

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
  • 25 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (765 reviews)
Great location, felt safe, clean room, good staff.

Reviewed on May 15, 2026

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane Jackson MO
  • 26 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (1,003 reviews)
The room was very spacious and very clean

Reviewed on May 15, 2026

Drury Inn & Suites Jackson MO
Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 out of 5
2904 Old Orchard Rd Jackson MO
  • 25 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
8.2/10 Very Good! (766 reviews)
Air Conditioning was noisy, the bathroom door did not close. The linens were dingy. The furniture was subpar, lots of damage on them scratches and dings. The carpet was stained and dirty, the bathroom had water damage around the tub and there were cracks in the ceiling drywall.

Reviewed on Apr 27, 2026

Comfort Suites Jackson-Cape Girardeau
Town House Inn

Town House Inn

2.5 out of 5
517 E Jackson Blvd Jackson MO
  • 31 min drive from Trail of Tears State Park
Stay at this motel in Jackson. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (442 reviews)
It was a cute little place with a nice little kitten with regular stove, microwave & good size refrigerator. Didn’t have plastic ware or dishes but did have coffee and the pot.

Reviewed on May 10, 2026

Town House Inn
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
  • 27 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,003 reviews)
Really did not enjoy the stay

Reviewed on May 15, 2026

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
  • 22 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Century Casino & Hotel Cape ...
9.4/10 Exceptional! (571 reviews)
The room and view were amazing!

Reviewed on May 15, 2026

The Riverview
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

3 out of 5
433 CAPE WEST CROSSINGS Cape Girardeau MO
  • 29 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fort D Historic Site and ...
9.4/10 Exceptional! (183 reviews)
The hotel room was very clean and the beds were comfortable, which made for a good night’s sleep. The staff was friendly and the overall stay was pleasant. The only downside was the breakfast. The food selection was limited and the quality was disappointing. Other than breakfast, the hotel experience ...

Reviewed on May 11, 2026

Fairfield Inn & Suites by Marriott Cape Girardeau
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy Cape Girardeau MO
  • 28 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,000 reviews)
Excellent layover stay

Reviewed on May 12, 2026

Pear Tree Inn Cape Girardeau West
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 out of 5
485 S Mount Auburn Rd Cape Girardeau MO
  • 29 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (934 reviews)
Sorry to say but the garbage in bathroom had not been picked up before we got there. And the coffee provided was stale dated and stale when I made it. That was a bummer first thing in the morning! The room was comfy and clean to the max besides!

Reviewed on May 13, 2026

Candlewood Suites Cape Girardeau by IHG
Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

2.5 out of 5
2011 North Kingshighway Cape Girardeau MO
  • 24 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7.2/10 Good! (740 reviews)
The place was not good at all. If it wasn't for it being so late at night when we arrived, I would have left and demanded a refund. Room was as if someone before me had just left 5 minutes prior to me going in. Not clean at all!!

Reviewed on May 6, 2026

Quality Inn Cape Girardeau North
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3 out of 5
400 Broadway St. Cape Girardeau MO
  • 24 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
9.6/10 Exceptional! (506 reviews)
Wow! Zero complaints. Perfect stay. Great value.

Reviewed on May 7, 2026

Courtyard by Marriott Cape Girardeau Downtown
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive Cape Girardeau MO
  • 28 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (1,000 reviews)
Excellent hotel! We enjoy the perks of an evening meal and a good breakfast. Rooms are well maintained and clean.

Reviewed on May 12, 2026

Drury Inn & Suites Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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