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Choose from 228 Jackson Hotel Deals

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
  • 25 min drive from Trail of Tears State Park
Stay at this 3-star business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (634 reviews)
"Clean"

Reviewed on Oct 8, 2025

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane, Jackson, MO
  • 26 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (1,009 reviews)
"Our stay was very enjoyable!! All Staff Members were very Professional and Friendly! Room was excellent, & comfortable! Evening meal & refreshment's,plus the hot breakfast were excellent!!"

Reviewed on Oct 11, 2025

Drury Inn & Suites Jackson MO
Town House Inn

Town House Inn

2.5 out of 5
517 E Jackson Blvd, Jackson, MO
  • 31 min drive from Trail of Tears State Park
Stay at this motel in Jackson. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (417 reviews)
"clean for the most part"

Reviewed on Oct 2, 2025

Town House Inn
Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 out of 5
2904 Old Orchard Rd, Jackson, MO
  • 25 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
8/10 Very Good! (735 reviews)
"Clean and comfortable every time. This is a “go to” hotel"

Reviewed on Oct 12, 2025

Comfort Suites Jackson-Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
  • 27 min drive from Trail of Tears State Park
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,014 reviews)
"Everything was perfect, staff friendly and room was very clean. Breakfast was very good. Checkout went very smooth. Thank you!"

Reviewed on Oct 10, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

2 out of 5
777 Main St, Cape Girardeau, MO
  • 22 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau ...
9.2/10 Wonderful! (432 reviews)
"Newer hotel so clean. Walk-in shower with no door but works. Control is on opposite side of shower head so alittle awkward. Starbucks was nice. Front desk very accommodating. Close to old downtown but too far to walk. Railroad tracks on east side but didn’t reallly hear."

Reviewed on Oct 7, 2025

The Riverview
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
  • 28 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,006 reviews)
"Close to the interstate so easy to get to when traveling. Nice property - plus that Outback Steakhouse is right next door for dining. We have stayed here numerous times over the years and always pleased."

Reviewed on Oct 9, 2025

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO
  • 28 min drive from Trail of Tears State Park
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (1,006 reviews)
"Friendly Staff"

Reviewed on Oct 12, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

2.5 out of 5
2520 Veterans Memorial Dr, Cape Girardeau, MO
  • 24 min drive from Trail of Tears State Park
Stay at this hotel in Cape Girardeau. Enjoy free breakfast, free parking, and a fitness center. Popular attractions Cape Girardeau Conservation Nature Center ...
9.4/10 Exceptional! (74 reviews)
"Everyone was so nice, patient & kind. Breakfast was delicious. The stay was awesome."

Reviewed on Sep 28, 2025

Tru By Hilton Cape Girardeau
Quality Inn

Quality Inn

2.5 out of 5
2011 North Kingshighway, Cape Girardeau, MO
  • 24 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7/10 Good! (649 reviews)
"It was fine"

Reviewed on Oct 5, 2025

Quality Inn
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
  • 29 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (855 reviews)
"Staff was very helpful and made check in easy! Our room is so roomy and clean. We have big dogs so plenty of room for them and they have hooks to hang leashes!!!"

Reviewed on Oct 12, 2025

Candlewood Suites Cape Girardeau by IHG
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3 out of 5
400 Broadway St., Cape Girardeau, MO
  • 24 min drive from Trail of Tears State Park
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
9.4/10 Exceptional! (455 reviews)
"Clean room."

Reviewed on Oct 9, 2025

Courtyard by Marriott Cape Girardeau Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Jackson

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