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La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
  • 25 min drive from Trail of Tears State Park
Stay at this 3-star business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (623 reviews)
"Clean room and breakfast area!"

Reviewed on Sep 18, 2025

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane, Jackson, MO
  • 26 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (1,014 reviews)
"this place is awesome! evening snacks and drinks (a meal really!) and very nice breakfast comfortable bed and beautiful grounds-quite rural, but Dairy Queen across the road. easy and safe seeming parking"

Reviewed on Sep 22, 2025

Drury Inn & Suites Jackson MO
Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 out of 5
2904 Old Orchard Rd, Jackson, MO
  • 25 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
8/10 Very Good! (734 reviews)
"Very nice and comfortable"

Reviewed on Jul 27, 2025

Comfort Suites Jackson-Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
  • 27 min drive from Trail of Tears State Park
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,017 reviews)
"Breakfast and kick-back were excellent. Wish the kick-back hours could be a little longer."

Reviewed on Sep 21, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

2 out of 5
777 Main St, Cape Girardeau, MO
  • 22 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau ...
9.2/10 Wonderful! (420 reviews)
"Helpful staff."

Reviewed on Sep 19, 2025

The Riverview
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO
  • 28 min drive from Trail of Tears State Park
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (1,008 reviews)
"Staff was friendly, room was clean, good location, good rate."

Reviewed on Sep 22, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
  • 28 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,009 reviews)
"I paid more then it said I would for reservation it said 78 and I was charged 129"

Reviewed on Sep 22, 2025

Pear Tree Inn Cape Girardeau West
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3 out of 5
400 Broadway St., Cape Girardeau, MO
  • 24 min drive from Trail of Tears State Park
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
9.4/10 Exceptional! (450 reviews)
"My husband and I love this hotel. We stay here every single time we are in the area. While it’s a little pricier than a few other options it is definitely worth it for us. The hotel is beautiful and the staff is always very accommodating. Emily and the rest of the staff are so sweet and helpful. ..."

Reviewed on Sep 21, 2025

Courtyard by Marriott Cape Girardeau Downtown
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 out of 5
120 MUDDY MONSTER ROAD, Murphysboro, IL
  • 1 hour drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Murphysboro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (479 reviews)
Quiet n great breakfast
"A variety of food choices n very good"

Reviewed on Sep 7, 2025

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 out of 5
433 CAPE WEST CROSSINGS, Cape Girardeau, MO
  • 29 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fort D Historic Site and ...
9.2/10 Wonderful! (128 reviews)
"A"

Reviewed on Sep 3, 2025

Fairfield Inn & Suites by Marriott Cape Girardeau
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

2.5 out of 5
2520 Veterans Memorial Dr, Cape Girardeau, MO
  • 24 min drive from Trail of Tears State Park
Stay at this hotel in Cape Girardeau. Enjoy free breakfast, free parking, and a fitness center. Popular attractions Cape Girardeau Conservation Nature Center ...
9.4/10 Exceptional! (63 reviews)
"Trip on our way to camp up north. Wonderful service and warm cookies and milk at night. Service was wonderful and the people were great. Clean and comfortable. Will be staying again on our way back south."

Reviewed on Sep 22, 2025

Tru By Hilton Cape Girardeau
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
  • 29 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
8/10 Very Good! (848 reviews)
"Great staff and convenient location"

Reviewed on Sep 23, 2025

Candlewood Suites Cape Girardeau by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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