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Choose from 240 Jackson Hotel Deals

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
  • 25 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (708 reviews)
Nice clean room. The breakfast could be improved but overall a good comfortable stay.

Reviewed on Feb 17, 2026

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane Jackson MO
  • 26 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (1,006 reviews)
I had a good stay. Clean room and a friendly staff.

Reviewed on Feb 18, 2026

Drury Inn & Suites Jackson MO
Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 out of 5
2904 Old Orchard Rd Jackson MO
  • 25 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
8.2/10 Very Good! (742 reviews)
Front desk guy was

Reviewed on Feb 17, 2026

Comfort Suites Jackson-Cape Girardeau
Town House Inn

Town House Inn

2.5 out of 5
517 E Jackson Blvd Jackson MO
  • 31 min drive from Trail of Tears State Park
Stay at this motel in Jackson. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (435 reviews)
owner could not speak english enough to understand and charged my credit card when i was supposed to be able to pay cash

Reviewed on Feb 13, 2026

Town House Inn
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
  • 27 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,005 reviews)
They were very nice people and very considerate to my situation. I would stay there anytime and recommend to everyone

Reviewed on Feb 20, 2026

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
  • 22 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau ...
9.4/10 Exceptional! (510 reviews)
I rested well!

Reviewed on Feb 21, 2026

The Riverview
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive Cape Girardeau MO
  • 28 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (1,003 reviews)
Friendly staff, great amneties, spotless, relaxing. We always look for Drurys wherever we go.

Reviewed on Feb 15, 2026

Drury Inn & Suites Cape Girardeau
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 out of 5
485 S Mount Auburn Rd Cape Girardeau MO
  • 29 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (896 reviews)
The room itsself was exceptional. Everything was spotless and the beds are very comfortable. However, it was extremely noisy!! The arcade on the 4th floor kept kids running up and down the halls. I thought it strange that housekeeping will not bring towels to your room when requested, instead you ...

Reviewed on Jan 24, 2026

Candlewood Suites Cape Girardeau by IHG
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy Cape Girardeau MO
  • 28 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,001 reviews)
Wonderful stay! Was in Cape Girardeau for Volleyball tournament. The check-in was easy, and a bit earlier than normal time. Very clean rooms with super comfortable beds and pillows & clean smell. Exceptional lighting and spacious bathroom. Popcorn and soda in the evening & an outstanding hot breakfast; ...

Reviewed on Feb 17, 2026

Pear Tree Inn Cape Girardeau West
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3 out of 5
400 Broadway St. Cape Girardeau MO
  • 24 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff ...
9.6/10 Exceptional! (489 reviews)
Amazing stay. Very clean. Staff was wonderful.

Reviewed on Feb 16, 2026

Courtyard by Marriott Cape Girardeau Downtown
Quality Inn

Quality Inn

2.5 out of 5
2011 North Kingshighway Cape Girardeau MO
  • 24 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7.2/10 Good! (699 reviews)
Well done

Reviewed on Feb 9, 2026

Quality Inn
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
3253 William Street Cape Girardeau MO
  • 28 min drive from Trail of Tears State Park
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,002 reviews)
Would have been a 5 rating except for the noisy heating system.

Reviewed on Feb 2, 2026

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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