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Tonight May 18 - May 19Next weekend May 24 - May 26

Choose from 217 Jackson Hotel Deals

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
  • 28 min drive from Trail of Tears State Park
The price is $64 per night from May 23 to May 24
$64
per night
May 23 - May 24
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,000 reviews)
"We never heard another person. Staff was wonderful."

Reviewed on May 12, 2024

Pear Tree Inn Cape Girardeau West
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
2.5 out of 5
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
  • 25 min drive from Trail of Tears State Park
The price is $84 per night from Jun 2 to Jun 3
$84
per night
Jun 2 - Jun 3
Book a stay at this business-friendly hotel in Jackson. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (373 reviews)
"A nice, clean , quiet property. Very good buy"

Reviewed on Apr 29, 2024

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
2.5 out of 5
2904 Old Orchard Rd, Jackson, MO
  • 25 min drive from Trail of Tears State Park
The price is $98 per night from Jun 2 to Jun 3
$98
per night
Jun 2 - Jun 3
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
8.2/10 Very Good! (637 reviews)
"Clean comfortable room"

Reviewed on May 12, 2024

Comfort Suites Jackson-Cape Girardeau
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
3 out of 5
225 Drury Lane, Jackson, MO
  • 26 min drive from Trail of Tears State Park
The price is $108 per night from May 26 to May 27
$108
per night
May 26 - May 27
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (955 reviews)
Great Hotel
"Good quality clean hotel. Our family stayed for a soccer tournament and would stay again."

Reviewed on May 15, 2024

Drury Inn & Suites Jackson MO
Town House Inn
Town House Inn
2.5 out of 5
517 E Jackson Blvd, Jackson, MO
  • 31 min drive from Trail of Tears State Park
The price is $82 per night from May 19 to May 20
$82
per night
May 19 - May 20
Stay at this motel in Jackson. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Litz Park and Lazy L Safari Park are located ...
8/10 Very Good! (290 reviews)
Soccer Family
"We were in town for a soccer tournament and was looking for a comfortable yet affordable weekend stay. Over all we were very satisified and will stay here again next year. Hotel was quit and clean. the full kitchen was a blessing to have for a family trip. easy access to ice and had coin oporated ..."

Reviewed on May 10, 2024

Town House Inn
Auburn Place Hotel And Suites
Auburn Place Hotel And Suites
2.5 out of 5
3265 William St, Cape Girardeau, MO
  • 28 min drive from Trail of Tears State Park
The price is $79 per night from May 23 to May 24
$79
per night
May 23 - May 24
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the ...
8.6/10 Excellent! (1,003 reviews)
"18 years ago, my wife and I stayed in the honeymoon suite and it was wonderful. This time, we had the opportunity to stay there with our son and it was wonderful. The staff was very friendly and immediately took care of getting us checked-in so that we could make in time for our niece’s graduation. ..."

Reviewed on May 13, 2024

Auburn Place Hotel And Suites
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 out of 5
3253 William Street, Cape Girardeau, MO
  • 28 min drive from Trail of Tears State Park
The price is $115 per night from May 26 to May 27
$115
per night
May 26 - May 27
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (999 reviews)
"Very nice hotel."

Reviewed on May 12, 2024

Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3 out of 5
3303 Campster Drive, Cape Girardeau, MO
  • 28 min drive from Trail of Tears State Park
The price is $108 per night from May 23 to May 24
$108
per night
May 23 - May 24
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (781 reviews)
"Excellent and Great Saff."

Reviewed on May 17, 2024

Drury Inn & Suites Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
  • 27 min drive from Trail of Tears State Park
The price is $112 per night from May 23 to May 24
$112
per night
May 23 - May 24
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool ...
9.6/10 Exceptional! (1,001 reviews)
"Great place to stay!"

Reviewed on May 5, 2024

Drury Plaza Hotel Cape Girardeau Conference Center
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
  • 28 min drive from Trail of Tears State Park
The price is $67 per night from May 26 to May 27
$67
per night
May 26 - May 27
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,000 reviews)
Good price & clean
"Reasonably price, clean, comfortable bed the only down fall is the rooms were tiny!"

Reviewed on May 12, 2024

Pear Tree Inn Cape Girardeau Near the Medical Center
Candlewood Suites Cape Girardeau, an IHG Hotel
Candlewood Suites Cape Girardeau, an IHG Hotel
2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
  • 29 min drive from Trail of Tears State Park
The price is $86 per night from May 26 to May 27
$86
per night
May 26 - May 27
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the clean rooms in our ...
8/10 Very Good! (622 reviews)
"Per friendly"

Reviewed on May 13, 2024

Candlewood Suites Cape Girardeau, an IHG Hotel
Quality Inn
Quality Inn
2.5 out of 5
2011 North Kingshighway, Cape Girardeau, MO
  • 24 min drive from Trail of Tears State Park
The price is $67 per night from May 19 to May 20
$67
per night
May 19 - May 20
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation ...
6.8/10 (459 reviews)
"Easy snd comfy"

Reviewed on May 11, 2024

Quality Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Jackson

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Jackson.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Jackson’s 217 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $64. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Jackson hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Jackson. No matter your reason for visiting Jackson, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Jackson hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Jackson for as low as $64.

How many hotels are there in Jackson?

With over 217 hotels in Jackson, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $64.

How to find cheap car rentals in Jackson?

Finding a cheap car rental deal in Jackson is as easy as scoring cheap hotels in Jackson. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Jackson now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Jackson right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.