Search for Cheap Deals on
Hotels in Jackson

Check Last Minute Jackson Hotel Deals

Tonight Apr 4 - Apr 5Next weekend Apr 10 - Apr 12

Choose from 252 Jackson Hotel Deals

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
  • 25 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (737 reviews)
Very helpful staff. We were able to use the CCS charger and charge to 100% both nights we stayed. I also enjoyed the gym.

Reviewed on Apr 4, 2026

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane Jackson MO
  • 26 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (1,000 reviews)
Beautiful property well staffed and maintained

Reviewed on Apr 1, 2026

Drury Inn & Suites Jackson MO
Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 out of 5
2904 Old Orchard Rd Jackson MO
  • 25 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
8.2/10 Very Good! (756 reviews)
Rooms were clean, AC worked great and the staff was friendly

Reviewed on Apr 3, 2026

Comfort Suites Jackson-Cape Girardeau
Town House Inn

Town House Inn

2.5 out of 5
517 E Jackson Blvd Jackson MO
  • 31 min drive from Trail of Tears State Park
Stay at this motel in Jackson. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (440 reviews)
Great owners

Reviewed on Mar 3, 2026

Town House Inn
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
  • 27 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,003 reviews)
Great stay as always.

Reviewed on Apr 3, 2026

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
  • 22 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau ...
9.4/10 Exceptional! (539 reviews)
Clean room. Nice view.

Reviewed on Apr 3, 2026

The Riverview
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive Cape Girardeau MO
  • 28 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (1,005 reviews)
Wonderful. I will definitely stay here again.

Reviewed on Apr 3, 2026

Drury Inn & Suites Cape Girardeau
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy Cape Girardeau MO
  • 28 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,002 reviews)
Everything was awesome

Reviewed on Apr 3, 2026

Pear Tree Inn Cape Girardeau West
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
3253 William Street Cape Girardeau MO
  • 28 min drive from Trail of Tears State Park
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,002 reviews)
Hotel is in a convenient central area. Was clean and staff was friendly.

Reviewed on Mar 30, 2026

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

2.5 out of 5
2011 North Kingshighway Cape Girardeau MO
  • 24 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7.2/10 Good! (722 reviews)
It was a clean room at a fair price. No frills but clean and staff were polite.

Reviewed on Mar 31, 2026

Quality Inn Cape Girardeau North
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 out of 5
485 S Mount Auburn Rd Cape Girardeau MO
  • 29 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (913 reviews)
Everything was good

Reviewed on Apr 1, 2026

Candlewood Suites Cape Girardeau by IHG
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

3 out of 5
433 CAPE WEST CROSSINGS Cape Girardeau MO
  • 29 min drive from Trail of Tears State Park
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fort D Historic Site and ...
9.4/10 Exceptional! (169 reviews)
Nice room, good breakfast

Reviewed on Apr 3, 2026

Fairfield Inn & Suites by Marriott Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Jackson

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Jackson hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Jackson.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Jackson’s 252 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $75. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Jackson hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Jackson. No matter your reason for visiting Jackson, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Jackson hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Jackson for as low as $75.

How many hotels are there in Jackson?

With over 252 hotels in Jackson, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $75.

How to find cheap car rentals in Jackson?

Finding a cheap car rental deal in Jackson is as easy as scoring cheap hotels in Jackson. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.