Search Cheap Flights toSouthern Illinois
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Southern Illinois Flights as Low as $202
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Tue, Nov 18 - Wed, Nov 19
SAT
San Antonio Intl.
STL
Lambert-St. Louis Intl.
$202 Roundtrip, found 1 day ago
$202
Roundtrip
found 1 day ago
Tue, Nov 18 - Mon, Nov 24
SAT
San Antonio Intl.
STL
Lambert-St. Louis Intl.
$205 Roundtrip, found 2 days ago
$205
Roundtrip
found 2 days ago
Tue, Nov 18 - Wed, Nov 19
SAT
San Antonio Intl.
STL
Lambert-St. Louis Intl.
$207 Roundtrip, found 1 day ago
$207
Roundtrip
found 1 day ago
Tue, Nov 18 - Wed, Nov 19
SAT
San Antonio Intl.
STL
Lambert-St. Louis Intl.
$207 Roundtrip, found 1 day ago
$207
Roundtrip
found 1 day ago
Sat, Nov 22 - Mon, Nov 24
SAT
San Antonio Intl.
STL
Lambert-St. Louis Intl.
$209 Roundtrip, found 2 days ago
$209
Roundtrip
found 2 days ago
Tue, Nov 18 - Wed, Nov 19
SAT
San Antonio Intl.
STL
Lambert-St. Louis Intl.
$210 Roundtrip, found 1 day ago
$210
Roundtrip
found 1 day ago
Sat, Nov 22 - Mon, Nov 24
SAT
San Antonio Intl.
STL
Lambert-St. Louis Intl.
$213 Roundtrip, found 2 days ago
$213
Roundtrip
found 2 days ago
Mon, Nov 17 - Sun, Nov 23
SAT
San Antonio Intl.
STL
Lambert-St. Louis Intl.
$215 Roundtrip, found 2 days ago
$215
Roundtrip
found 2 days ago
Sat, Nov 22 - Mon, Nov 24
SAT
San Antonio Intl.
STL
Lambert-St. Louis Intl.
$218 Roundtrip, found 2 days ago
$218
Roundtrip
found 2 days ago
Tue, Nov 18 - Thu, Nov 20
SAT
San Antonio Intl.
STL
Lambert-St. Louis Intl.
$223 Roundtrip, found 2 days ago
$223
Roundtrip
found 2 days ago
Tue, Nov 18 - Wed, Nov 19
SAT
San Antonio Intl.
STL
Lambert-St. Louis Intl.
$225 Roundtrip, found 1 day ago
$225
Roundtrip
found 1 day ago
Tue, Nov 18 - Wed, Nov 19
SAT
San Antonio Intl.
STL
Lambert-St. Louis Intl.
$229 Roundtrip, found 1 day ago
$229
Roundtrip
found 1 day ago
Mon, Nov 17 - Sun, Nov 23
SAT
San Antonio Intl.
STL
Lambert-St. Louis Intl.
$232 Roundtrip, found 2 days ago
$232
Roundtrip
found 2 days ago
Tue, Nov 18 - Wed, Nov 19
SAT
San Antonio Intl.
STL
Lambert-St. Louis Intl.
$233 Roundtrip, found 1 day ago
$233
Roundtrip
found 1 day ago
Tue, Jul 15 - Sat, Jul 19
SAT
San Antonio Intl.
STL
Lambert-St. Louis Intl.
$342 Roundtrip, found 2 days ago
$342
Roundtrip
found 2 days ago
Sat, Jul 5 - Tue, Jul 8
SAT
San Antonio Intl.
MWA
Williamson County Regional
$922 Roundtrip, found 2 days ago
$922
Roundtrip
found 2 days ago
Cheap Flights to Southern Illinois
Fall in love at first flight with your vacation to Southern Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southern Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.
Because once the wheels are down in Southern Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.
Frequently Asked Questions About flights to Southern Illinois
Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southern Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.
So all you have to worry about is where you’re headed after the STL airport.
What is the cheapest month to fly to Southern Illinois?
Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southern Illinois are in November, but when you book your flight on Hotwire, savings are always in season.
How many airlines fly to Southern Illinois?
Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 14 to choose from for your flight to Southern Illinois.
What airport is best to fly into Southern Illinois?
When you’re planning your trip to Southern Illinois, convenience is the name of the game. Luckily, Southern Illinois Williamson County Regional Airport is nearby so you can deplane and get going on checking off everything on your Southern Illinois must-do list.
How much are flights to Southern Illinois?
Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southern Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $202, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.
How to get cheap flights to Southern Illinois?
The trick to saving a stack of cash on your flight to Southern Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $202 right now, why wait?
Destination airport | Lambert-St. Louis Intl. |
Destination airport IATA code | STL |
Roundtrip price | $92 |
Last Minute Hotel Deals in Southern Illinois
Drury Plaza Hotel Mt. Vernon
145 North 44th Street , Mount Vernon, IL
Stay at this 3-star business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,376 reviews)
"Quiet, comfortable bed, clean room, super friendly staff, and great breakfast"
Reviewed on Jul 2, 2025
Best Western Plus Pontoon Beach
4 Regency Pkwy, Granite City, IL
Stay at this 3-star business-friendly hotel in Granite City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (683 reviews)
"Close parking, excellent staff, very accommodating of accessibility requests, quiet area."
Reviewed on Jun 30, 2025
Days Inn & Suites by Wyndham Caseyville
2423 Old Country Inn Drive, Caseyville, IL
Book a stay at this business-friendly hotel in Caseyville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pleasant Ridge Park and Cahokia ...
3.8/10 (242 reviews)
"Maybe they need to repair the ice machine and bring back the snacks machines with card options. Maybe a convenient store inside. Repair the coin washer plus other things. But I still think it’s the best option to do the main things you do on a room: rest and be relaxed."
Reviewed on Jun 30, 2025
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr, Fairview Heights, IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,003 reviews)
"Nice staff, great breakfast, clean rooms"
Reviewed on Jun 24, 2025
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr, O'Fallon, IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.4/10 Good! (1,001 reviews)
"The room we stayed in was huuuuuge. I thought i walked in the wrong room at first. Outdoor pool was nice. Staff was wonderful and accomodating. Had an issue with my tv but they made sure to help with it right away"
Reviewed on Jun 29, 2025
Red Lion Inn & Suites Pontoon Beach
1240 E Chain Of Rocks Rd, Granite City, IL
Stay at this hotel in Granite City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.8/10 Good! (415 reviews)
"Inexpensive & clean"
Reviewed on Jun 30, 2025
Drury Inn & Suites Marion
2706 W DeYoung St, Marion, IL
Stay at this 3-star business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,002 reviews)
"It was nice to feel safe! the property was well maintained. With the offer of up to 3 drinks per guest it allowed us a place to sit and chat for a couple hours instead of trying to sit on the beds in the rooms and chat. I meet 2 different family members there for just a night, we appreciate the facility ..."
Reviewed on Jun 29, 2025
Radisson Hotel Fairview Heights - St. Louis
319 Fountains Pkwy, Fairview Heights, IL
Stay at this 3-star business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7.4/10 Good! (455 reviews)
"Staff was friendly. Checking in and out was easy. Pool was open till 10 and open early in the morning. Breakfast was delicious had eggs, sausage, potatoes, biscuits and gravy, oatmeal, make your own waffles, cereal, choice of fruit and bagles"
Reviewed on Jul 1, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southern Illinois Hotels
- Best Western Plus Pontoon Beach
- Days Inn & Suites by Wyndham Caseyville
- Super 8 by Wyndham O'Fallon
- Red Lion Inn & Suites Pontoon Beach
- Radisson Hotel Fairview Heights - St. Louis
- Country Inn & Suites by Radisson, Effingham, IL
- Days Inn by Wyndham Pontoon Beach
- Baymont by Wyndham Effingham
- La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
- Super 8 by Wyndham Fairview Heights-St. Louis
- Country Inn & Suites by Radisson, Fairview Heights, IL