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Southern Illinois

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Southern Illinois Flights as Low as $128

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Thu, Jun 12 - Sat, Jun 14
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$128 Roundtrip, found 1 day ago
$128
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Jun 12 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Jun 14, priced at $128 found 1 day ago
Frontier Airlines
Thu, Jun 12 - Sun, Jun 15
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$148 Roundtrip, found 1 day ago
$148
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Thu, Jun 12 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sun, Jun 15, priced at $148 found 1 day ago
Frontier Airlines
Wed, Jun 4 - Sat, Jun 14
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$160 Roundtrip, found 5 days ago
$160
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Wed, Jun 4 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Jun 14, priced at $160 found 5 days ago
Spirit Airlines
Tue, Apr 15 - Tue, Apr 22
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$169 Roundtrip, found 19 hours ago
$169
Roundtrip
found 19 hours ago
Select Spirit Airlines flight, departing Tue, Apr 15 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Apr 22, priced at $169 found 19 hours ago
Spirit Airlines
Thu, Apr 17 - Tue, Apr 22
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$177 Roundtrip, found 4 days ago
$177
Roundtrip
found 4 days ago
Select Spirit Airlines flight, departing Thu, Apr 17 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Apr 22, priced at $177 found 4 days ago
Spirit Airlines
Tue, Apr 22 - Tue, Apr 29
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$179 Roundtrip, found 2 days ago
$179
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Tue, Apr 22 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Apr 29, priced at $179 found 2 days ago
Frontier Airlines
Wed, Jun 11 - Thu, Jun 12
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$181 Roundtrip, found 1 day ago
$181
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Jun 11 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Thu, Jun 12, priced at $181 found 1 day ago
American Airlines
Mon, Jun 9 - Thu, Jun 12
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$183 Roundtrip, found 1 day ago
$183
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Jun 9 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Thu, Jun 12, priced at $183 found 1 day ago
Delta
Thu, Jun 12 - Thu, Jun 12
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$192 Roundtrip, found 1 day ago
$192
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Jun 12 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Thu, Jun 12, priced at $192 found 1 day ago
American Airlines
Mon, Jun 9 - Thu, Jun 12
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$217 Roundtrip, found 1 day ago
$217
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Jun 9 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Thu, Jun 12, priced at $217 found 1 day ago
United
Wed, Apr 16 - Sun, Apr 20
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$231 Roundtrip, found 10 hours ago
$231
Roundtrip
found 10 hours ago
Select United flight, departing Wed, Apr 16 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sun, Apr 20, priced at $231 found 10 hours ago
Frontier Airlines
Thu, May 8 - Sun, May 11
LAX
Los Angeles Intl.
STL
Lambert-St. Louis Intl.
$274 Roundtrip, found 1 hour ago
$274
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Thu, May 8 from Los Angeles Intl. to Lambert-St. Louis Intl., returning Sun, May 11, priced at $274 found 1 hour ago
Bargain Flight
Wed, Apr 9 - Wed, Apr 16
LAX
Los Angeles Intl.
STL
Lambert-St. Louis Intl.
$331 Roundtrip, found 16 hours ago
$331
Roundtrip
found 16 hours ago
Select Bargain Flight flight, departing Wed, Apr 9 from Los Angeles Intl. to Lambert-St. Louis Intl., returning Wed, Apr 16, priced at $331 found 16 hours ago
Delta
Mon, May 5 - Fri, May 16
ATL
Hartsfield-Jackson Atlanta Intl.
EVV
Evansville Regional
$363 Roundtrip, found 4 days ago
$363
Roundtrip
found 4 days ago
Select Delta flight, departing Mon, May 5 from Hartsfield-Jackson Atlanta Intl. to Evansville Regional, returning Fri, May 16, priced at $363 found 4 days ago
Hawaiian Airlines
Fri, Apr 4 - Tue, Apr 15
LAX
Los Angeles Intl.
STL
Lambert-St. Louis Intl.
$505 Roundtrip, found 2 days ago
$505
Roundtrip
found 2 days ago
Select Hawaiian Airlines flight, departing Fri, Apr 4 from Los Angeles Intl. to Lambert-St. Louis Intl., returning Tue, Apr 15, priced at $505 found 2 days ago
American Airlines
Sat, Mar 29 - Tue, Apr 1
LAX
Los Angeles Intl.
EVV
Evansville Regional
$678 Roundtrip, found 2 days ago
$678
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Mar 29 from Los Angeles Intl. to Evansville Regional, returning Tue, Apr 1, priced at $678 found 2 days ago

Cheap Flights to Southern Illinois

Fall in love at first flight with your vacation to Southern Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southern Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southern Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southern Illinois

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southern Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Southern Illinois?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southern Illinois are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southern Illinois?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Southern Illinois.

What airport is best to fly into Southern Illinois?

When you’re planning your trip to Southern Illinois, convenience is the name of the game. Luckily, Southern Illinois Williamson County Regional Airport is nearby so you can deplane and get going on checking off everything on your Southern Illinois must-do list.

How much are flights to Southern Illinois?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southern Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $128, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southern Illinois?

The trick to saving a stack of cash on your flight to Southern Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $128 right now, why wait?

Southern Illinois Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$128

Last Minute Hotel Deals in Southern Illinois

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon
3 out of 5
145 North 44th Street , Mount Vernon, IL
The price is $117 per night from Apr 6 to Apr 7
$117
per night
Apr 6 - Apr 7
Stay at this 3-star business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,270 reviews)
"Super clean and well maintained. Comfy beds. Evening social good. Breakfast was really good with lots of options. Spacious room. Dining options nearby. Great place!"

Reviewed on Mar 23, 2025

Drury Plaza Hotel Mt. Vernon
Super 8 by Wyndham O'Fallon
Super 8 by Wyndham O'Fallon
2 out of 5
1100 Eastgate Dr, O'Fallon, IL
The price is $59 per night from Mar 31 to Apr 1
$59
per night
Mar 31 - Apr 1
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,001 reviews)
"It was an all around splendid stay service was nice and rooms where cleanwill be staying again soon"

Reviewed on Mar 21, 2025

Super 8 by Wyndham O'Fallon
Red Lion Inn & Suites Pontoon Beach
Red Lion Inn & Suites Pontoon Beach
2.5 out of 5
1240 E Chain Of Rocks Rd, Granite City, IL
The price is $78 per night from Mar 31 to Apr 1
$78
per night
Mar 31 - Apr 1
Stay at this hotel in Granite City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
8/10 Very Good! (297 reviews)
"My trip was really comfortable and relaxing. I stayed here solo. Good cable convenient location good breakfast and very comfortable and quiet"

Reviewed on Mar 16, 2025

Red Lion Inn & Suites Pontoon Beach
Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites St. Louis O'Fallon, IL
3 out of 5
1118 Central Park Drive, O'Fallon, IL
The price is $125 per night from Mar 30 to Mar 31
$125
per night
Mar 30 - Mar 31
Stay at this 3-star business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,005 reviews)
"Hotel is clean and quiet with excellent customer service."

Reviewed on Mar 21, 2025

Drury Inn & Suites St. Louis O'Fallon, IL
Quality Inn & Suites near St. Louis and I-255
Quality Inn & Suites near St. Louis and I-255
2.5 out of 5
1607 Pontiac Dr, East St. Louis, IL
The price is $71 per night from Apr 1 to Apr 2
$71
per night
Apr 1 - Apr 2
Book a stay at this business-friendly hotel in East St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
7.4/10 Good! (999 reviews)
"My daughters very much enjoyed the indoor pool. The room was very spacious which was nice with two kids with me. We felt like it was quiet and didn't feel unsafe at any point. Very close in proximity to the St. Louis area which is where we were spending our day."

Reviewed on Mar 22, 2025

Quality Inn & Suites near St. Louis and I-255
Red Lion Inn & Suites Caseyville
Red Lion Inn & Suites Caseyville
2 out of 5
8950 Tucker Dr, Caseyville, IL
The price is $60 per night from Apr 6 to Apr 7
$60
per night
Apr 6 - Apr 7
Stay at this motel in Caseyville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pleasant Ridge Park and Cahokia Mounds State Historic ...
5.4/10 (184 reviews)
"It was good and newly built no issues"

Reviewed on Mar 13, 2025

Red Lion Inn & Suites Caseyville
Walker's Bluff Casino Resort
Walker's Bluff Casino Resort
4.5 out of 5
777 Walkers Bluff Way, Carterville, IL
The price is $144 per night from Mar 26 to Mar 27
$144
per night
Mar 26 - Mar 27
Stay at this 4.5-star luxury resort in Carterville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (297 reviews)
"Very friendly staff and clean."

Reviewed on Mar 10, 2025

Walker's Bluff Casino Resort
Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites St. Louis Fairview Heights
3 out of 5
12 Ludwig Dr, Fairview Heights, IL
The price is $115 per night from Mar 30 to Mar 31
$115
per night
Mar 30 - Mar 31
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,006 reviews)
"It was nice…rooms could be cleaned better but overall I’ll stay again"

Reviewed on Mar 23, 2025

Drury Inn & Suites St. Louis Fairview Heights
See all 966 properties in Southern Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.