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Southern Illinois

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Southern Illinois Flights as Low as $102

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Breeze Airways
Fri, Aug 29 - Fri, Sep 5
MCO
Orlando Intl.
EVV
Evansville Regional
$102 Roundtrip, found 15 hours ago
$102
Roundtrip
found 15 hours ago
Select Breeze Airways flight, departing Fri, Aug 29 from Orlando Intl. to Evansville Regional, returning Fri, Sep 5, priced at $102 found 15 hours ago
Breeze Airways
Mon, Aug 25 - Fri, Aug 29
MCO
Orlando Intl.
EVV
Evansville Regional
$107 Roundtrip, found 18 hours ago
$107
Roundtrip
found 18 hours ago
Select Breeze Airways flight, departing Mon, Aug 25 from Orlando Intl. to Evansville Regional, returning Fri, Aug 29, priced at $107 found 18 hours ago
Breeze Airways
Mon, Aug 25 - Fri, Aug 29
MCO
Orlando Intl.
EVV
Evansville Regional
$112 Roundtrip, found 18 hours ago
$112
Roundtrip
found 18 hours ago
Select Breeze Airways flight, departing Mon, Aug 25 from Orlando Intl. to Evansville Regional, returning Fri, Aug 29, priced at $112 found 18 hours ago
Breeze Airways
Mon, Aug 25 - Fri, Aug 29
MCO
Orlando Intl.
EVV
Evansville Regional
$117 Roundtrip, found 18 hours ago
$117
Roundtrip
found 18 hours ago
Select Breeze Airways flight, departing Mon, Aug 25 from Orlando Intl. to Evansville Regional, returning Fri, Aug 29, priced at $117 found 18 hours ago
Breeze Airways
Fri, Aug 22 - Fri, Aug 29
MCO
Orlando Intl.
EVV
Evansville Regional
$122 Roundtrip, found 4 days ago
$122
Roundtrip
found 4 days ago
Select Breeze Airways flight, departing Fri, Aug 22 from Orlando Intl. to Evansville Regional, returning Fri, Aug 29, priced at $122 found 4 days ago
Spirit Airlines
Sat, Jul 12 - Wed, Jul 16
MCO
Orlando Intl.
STL
Lambert-St. Louis Intl.
$123 Roundtrip, found 3 days ago
$123
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Sat, Jul 12 from Orlando Intl. to Lambert-St. Louis Intl., returning Wed, Jul 16, priced at $123 found 3 days ago
Spirit Airlines
Wed, Jul 9 - Wed, Jul 16
MCO
Orlando Intl.
STL
Lambert-St. Louis Intl.
$143 Roundtrip, found 3 days ago
$143
Roundtrip
found 3 days ago
Select Spirit Airlines flight, departing Wed, Jul 9 from Orlando Intl. to Lambert-St. Louis Intl., returning Wed, Jul 16, priced at $143 found 3 days ago
Frontier Airlines
Thu, Jun 19 - Mon, Jun 23
MCO
Orlando Intl.
STL
Lambert-St. Louis Intl.
$162 Roundtrip, found 4 days ago
$162
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Jun 19 from Orlando Intl. to Lambert-St. Louis Intl., returning Mon, Jun 23, priced at $162 found 4 days ago
Spirit Airlines
Fri, Jul 4 - Wed, Jul 30
MCO
Orlando Intl.
STL
Lambert-St. Louis Intl.
$166 Roundtrip, found 2 days ago
$166
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Fri, Jul 4 from Orlando Intl. to Lambert-St. Louis Intl., returning Wed, Jul 30, priced at $166 found 2 days ago
Frontier Airlines
Sun, Jul 6 - Wed, Jul 30
MCO
Orlando Intl.
STL
Lambert-St. Louis Intl.
$171 Roundtrip, found 2 days ago
$171
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sun, Jul 6 from Orlando Intl. to Lambert-St. Louis Intl., returning Wed, Jul 30, priced at $171 found 2 days ago
Bargain Flight
Wed, Jul 9 - Sat, Jul 12
LAX
Los Angeles Intl.
STL
Lambert-St. Louis Intl.
$251 Roundtrip, found 12 hours ago
$251
Roundtrip
found 12 hours ago
Select Bargain Flight flight, departing Wed, Jul 9 from Los Angeles Intl. to Lambert-St. Louis Intl., returning Sat, Jul 12, priced at $251 found 12 hours ago
Delta
Sat, Aug 30 - Sun, Aug 31
MCO
Orlando Intl.
EVV
Evansville Regional
$259 Roundtrip, found 2 days ago
$259
Roundtrip
found 2 days ago
Select Delta flight, departing Sat, Aug 30 from Orlando Intl. to Evansville Regional, returning Sun, Aug 31, priced at $259 found 2 days ago
American Airlines
Mon, Aug 25 - Sun, Aug 31
MCO
Orlando Intl.
EVV
Evansville Regional
$268 Roundtrip, found 3 days ago
$268
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Aug 25 from Orlando Intl. to Evansville Regional, returning Sun, Aug 31, priced at $268 found 3 days ago
Alaska Airlines
Fri, Oct 24 - Mon, Oct 27
LAX
Los Angeles Intl.
STL
Lambert-St. Louis Intl.
$445 Roundtrip, found 1 day ago
$445
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Fri, Oct 24 from Los Angeles Intl. to Lambert-St. Louis Intl., returning Mon, Oct 27, priced at $445 found 1 day ago
Delta
Sat, Jun 7 - Tue, Jun 10
LAX
Los Angeles Intl.
EVV
Evansville Regional
$446 Roundtrip, found 1 day ago
$446
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Jun 7 from Los Angeles Intl. to Evansville Regional, returning Tue, Jun 10, priced at $446 found 1 day ago
American Airlines
Tue, Jun 17 - Mon, Jun 23
LAX
Los Angeles Intl.
CGI
Cape Girardeau Municipal
$508 Roundtrip, found 6 days ago
$508
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Jun 17 from Los Angeles Intl. to Cape Girardeau Municipal, returning Mon, Jun 23, priced at $508 found 6 days ago

Cheap Flights to Southern Illinois

Fall in love at first flight with your vacation to Southern Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southern Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southern Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southern Illinois

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southern Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Southern Illinois?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southern Illinois are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southern Illinois?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Southern Illinois.

What airport is best to fly into Southern Illinois?

When you’re planning your trip to Southern Illinois, convenience is the name of the game. Luckily, Southern Illinois Williamson County Regional Airport is nearby so you can deplane and get going on checking off everything on your Southern Illinois must-do list.

How much are flights to Southern Illinois?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southern Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $102, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southern Illinois?

The trick to saving a stack of cash on your flight to Southern Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $102 right now, why wait?

Southern Illinois Flight Information
Destination airport
Evansville Regional
Destination airport IATA code
EVV
Roundtrip price
$101

Last Minute Hotel Deals in Southern Illinois

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon
3 out of 5
145 North 44th Street , Mount Vernon, IL
Stay at this 3-star business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,339 reviews)
"The hotel itself is very nice. The staff are very professional and helpful. Got in after a long day of driving and was told at check in about the free meal they offered which was some good news as it meant the family wouldn’t have to jump back in a car for food, the food was really good as well! ..."

Reviewed on Jun 5, 2025

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Drury Plaza Hotel Mt. Vernon
Super 8 by Wyndham O'Fallon
Super 8 by Wyndham O'Fallon
2 out of 5
1100 Eastgate Dr, O'Fallon, IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,001 reviews)
"A"

Reviewed on Jun 5, 2025

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Super 8 by Wyndham O'Fallon
Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites St. Louis O'Fallon, IL
3 out of 5
1118 Central Park Drive, O'Fallon, IL
Stay at this 3-star business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,003 reviews)
"Greeted immediately upon arrival and she was efficient and professional."

Reviewed on Jun 4, 2025

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Drury Inn & Suites St. Louis O'Fallon, IL
Best Western Plus Pontoon Beach
Best Western Plus Pontoon Beach
3 out of 5
4 Regency Pkwy, Granite City, IL
Stay at this 3-star business-friendly hotel in Granite City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (648 reviews)
"Convenient, clean, friendly staff, no complaints!"

Reviewed on Jun 5, 2025

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Best Western Plus Pontoon Beach
Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites St. Louis Fairview Heights
3 out of 5
12 Ludwig Dr, Fairview Heights, IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,004 reviews)
"We have stayed here a couple of times and although an older property it is clean and the breakfast is good."

Reviewed on Jun 4, 2025

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Drury Inn & Suites St. Louis Fairview Heights
Walker's Bluff Casino Resort
Walker's Bluff Casino Resort
4.5 out of 5
777 Walkers Bluff Way, Carterville, IL
Stay at this 4.5-star luxury resort in Carterville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (338 reviews)
"Clean, friendly, and prompt."

Reviewed on Jun 2, 2025

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Walker's Bluff Casino Resort
Radisson Hotel Fairview Heights - St. Louis
Radisson Hotel Fairview Heights - St. Louis
3 out of 5
319 Fountains Pkwy, Fairview Heights, IL
Stay at this 3-star business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7.4/10 Good! (435 reviews)
"Good hotel"

Reviewed on Jun 3, 2025

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Radisson Hotel Fairview Heights - St. Louis
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
3 out of 5
136 Regency Park, O'Fallon, IL
Stay at this 3-star business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6.2/10 (1,000 reviews)
"The service was excellent, their housekeeping staff was friendly, timely and thorough."

Reviewed on May 29, 2025

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La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
See all 1,016 properties in Southern Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.