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Spa Resort Hotels in Southern Illinois

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Featured Southern Illinois Resorts & Hotels with Spas

Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites St. Louis Fairview Heights
3 out of 5
12 Ludwig Dr, Fairview Heights, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites Marion
Drury Inn & Suites Marion
3 out of 5
2706 W DeYoung St, Marion, IL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Drury Inn & Suites Marion
Holiday Inn Express Metropolis, an IHG Hotel
Holiday Inn Express Metropolis, an IHG Hotel
2.5 out of 5
2179 East 5th Street, Metropolis, IL
Fully refundable
Book a stay at this business-friendly hotel in Metropolis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Holiday Inn Express Metropolis, an IHG Hotel
Comfort Suites Mount Vernon
Comfort Suites Mount Vernon
2.5 out of 5
404 South 44th Street, Mount Vernon, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Comfort Suites Mount Vernon
Quality Inn O'Fallon IL - St. Louis
Quality Inn O'Fallon IL - St. Louis
3 out of 5
1409 W US 50, O'Fallon, IL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Quality Inn O'Fallon IL - St. Louis
Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, IL
2.5 out of 5
1200 N Raney, Effingham, IL
Fully refundable
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Country Inn & Suites by Radisson, Effingham, IL
Days Inn by Wyndham Pontoon Beach
Days Inn by Wyndham Pontoon Beach
2 out of 5
5105 Highway 111, Granite City, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Granite City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Long Lake and Horseshoe Lake ...
Days Inn by Wyndham Pontoon Beach
Baymont by Wyndham Metropolis
Baymont by Wyndham Metropolis
2.5 out of 5
203 E Front St, Metropolis, IL
Book a stay at this business-friendly motel in Metropolis. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. ...
Baymont by Wyndham Metropolis
Days Inn & Suites by Wyndham Caseyville
Days Inn & Suites by Wyndham Caseyville
2.5 out of 5
2423 Old Country Inn Drive, Caseyville, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Caseyville. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pleasant Ridge Park and Cahokia ...
Days Inn & Suites by Wyndham Caseyville
Americas Best Value Inn Mount Vernon
Americas Best Value Inn Mount Vernon
2.5 out of 5
222 South 44th Street, Mount Vernon, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
Americas Best Value Inn Mount Vernon
Clarion Pointe Mattoon near University
Clarion Pointe Mattoon near University
2.5 out of 5
206 Mcfall Rd, Mattoon, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Mattoon. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions Mattoon Peterson Park ...
Clarion Pointe Mattoon near University
Best Western Marion Hotel
Best Western Marion Hotel
2.5 out of 5
400 Comfort Dr, Marion, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Best Western Marion Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Book Spa Resorts and Hotels in Southern Illinois

Could you use an escape from the rat race? We all feel that way from time to time; it just means it's time for a getaway. If you're looking to really get away from it all, there's nothing better than scheduling a getaway to a spa resort in Southern Illinois. An assortment of services will be offered to you—from massages to facials, yoga classes, and more. No matter which services or treatments you select, you'll be whisked away to a whole new world of relaxation as your worries slip away. Leave the stress of getting around a new area, the hustle and bustle of big cities, and overcrowded tourist sites to other people. A spa and resort package in Southern Illinois lets you be treated like royalty, without a worry in the world other than being on time for your next facial. You could achieve such a state of relaxation that you never want to go home.

Relaxing in Southern Illinois

Visitors from all over the world are aware that there is a ton of cool things to do in Southern Illinois but not everyone knows about its reputation as a great area for a wellness retreat. Maybe you've come to spend some time experiencing the sites, trendiest restaurants, and the local charm that make Southern Illinois such a popular tourist destination and then plan to enjoy the last few days at a spa. Or, possibly you'd prefer a lengthier stay at one of our Southern Illinois spas. Whatever you decide, you'll be treated like a rock star and feeling like a champ when you book a room at one of our Southern Illinois spa resorts.

Book your Southern Illinois spa resort

An indulgent vacation in Southern Illinois is on your schedule. Obviously you're looking to decompress, so allow us to assist you in choosing the perfect resort by bringing together all of the best discounts on Southern Illinois spa resorts. If you want even bigger savings, check out Hotwire Hot Rates which gives you access to the best deals of all. Select the perfect resort for you based on:

  • Hotwire Hot Rates: Looking to discover the best discounts on your resort retreat? The name of the spa will be revealed once you make your reservation, but you're sure to be excited about where you're staying.
  • Price: You deserve to indulge. However, you don't need to blow through your savings to enjoy yourself. We have Southern Illinois spa packages for every budget. Maybe go ahead and spend some of that money you save on an additional massage.
  • Amenities: Standard spas feature facials and massages, but perhaps you're looking for something a bit special. Maybe you have your heart set on something more from the spa services menu, like a salt glow or a body wrap, or perhaps you want a personal advisor to assist in creating your schedule. Select the perfect spa to meet your needs.
  • Reviews: If you're in need of a little assistance figuring out which Southern Illinois spa to visit, scroll through the reviews on our site. A great way to put together an itinerary is by listening to previous travelers.

Hotwire has spa resorts in Southern Illinois, all of which will make for a vacation to remember. Make the year you indulge by reserving a spot at a Southern Illinois spa resort now.