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Featured Southern Illinois Family Hotels
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Country Inn & Suites by Radisson, Marion, IL
1306 Halfway Road, Marion, IL
Fully refundable
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
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Drury Plaza Hotel Mt. Vernon
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
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Rodeway Inn & Suites
116 Regency Park, O'Fallon, IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
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Holiday Inn Express And Suites Effingham, an IHG Hotel
1604 West Fayette Avenue, Effingham, IL
Fully refundable
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
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Best Western Troy Hotel
2020 Formosa Drive, Troy, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Troy. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
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La Quinta Inn & Suites by Wyndham Pontoon Beach
14 Regency Park Dr, Granite City, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Granite City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
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Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive, O'Fallon, IL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
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La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
6 Gateway Dr, Collinsville, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Collinsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
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Drury Inn & Suites Marion
2706 W DeYoung St, Marion, IL
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
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Harrah's Metropolis Hotel & Casino
100 E Front St, Metropolis, IL
Stay at this 3.5-star hotel in Metropolis. Enjoy free parking, 2 restaurants, and a casino. Our guests praise the helpful staff and the clean rooms in our reviews. ...
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Comfort Suites Mount Vernon
404 South 44th Street, Mount Vernon, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
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Hampton Inn & Suites Effingham
1305 N Keller Dr, Effingham, IL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels with Pools in Southern Illinois
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Holiday Inn Express And Suites Effingham, an IHG Hotel
1604 West Fayette Avenue, Effingham, IL
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,000 reviews)
"Friendly"
Reviewed on Feb 16, 2025
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Comfort Suites Mount Vernon
404 South 44th Street, Mount Vernon, IL
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,000 reviews)
"Very accessible, clean, quite and friendly. The rooms were fine and good size with a refrigerator/freezer, microwave and coffee. The free breakfast started early, which was helpful for traveling."
Reviewed on Feb 6, 2025
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Best Western Marion Hotel
400 Comfort Dr, Marion, IL
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,001 reviews)
"Near Cracker barrel. Limited truck, motor home or trailer parking in rear. Decent size parking lot. Breakfast was pretty good Staff very nice and personable"
Reviewed on Feb 19, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels With Connecting Rooms in Southern Illinois
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Quality Inn & Suites Vandalia near I-70 and Hwy 51
1920 Kennedy Boulevard, Vandalia, IL
Book a stay at this business-friendly hotel in Vandalia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
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Ramada by Wyndham Effingham
1606 W Fayette Avenue, Effingham, IL
Stay at this 3-star business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
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Baymont by Wyndham Effingham
1811 W Fayette Avenue, I-57 & 70 Exit 159, Effingham, IL
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options
- Hotels with Free Parking in Southern Illinois
- Pet-friendly Hotels in Southern Illinois
- Hotels with a Pool in Southern Illinois
- Hotels with an Indoor Pool in Southern Illinois
- Hotels with Hot Tubs in Southern Illinois
- Historic Hotels in Southern Illinois
- Luxury Hotels in Southern Illinois
- Resorts & Hotels with Spas in Southern Illinois
- Hotel Wedding Venues in Southern Illinois
- Winery Hotels in Southern Illinois
Top Points of Interests in Southern Illinois
- Hotels near Shawnee National Forest
- Hotels near Southern Illinois University
- Hotels near Garden of the Gods Recreation Area
- Hotels near Harrah's Metropolis
- Hotels near Lake of Egypt
- Hotels near Rend Lake
- Hotels near Scott Air Force Base
- Hotels near Giant City State Park
- Hotels near Superman Statue
- Hotels near Carlyle Lake
- Hotels near O'Fallon Family Sports Park
- Hotels near World Wide Technology Raceway
- Hotels near Cahokia Mounds State Historic Site
- Hotels near Marion Cultural and Civic Center
- Hotels near McKendree University
- Hotels near DuQuoin State Fairgrounds
- Hotels near Lake Sara
- Hotels near St. Claire Square Mall
- Hotels near Gateway Conference Center
- Hotels near Ferne Clyffe State Park
Cities near Southern Illinois
- St. Charles Hotels (93.9 mi)
- Evansville Hotels (74.5 mi)
- Paducah Hotels (92.61 mi)
- Maryland Heights Hotels (89.1 mi)
- Cape Girardeau Hotels (85.27 mi)
- Terre Haute Hotels (104.99 mi)
- Effingham Hotels (51.13 mi)
- Chesterfield Hotels (95.5 mi)
- Marion Hotels (47.47 mi)
- Carbondale Hotels (51.91 mi)
- O'Fallon Hotels (59.98 mi)
- Mount Vernon Hotels (7.84 mi)
- Decatur Hotels (98.88 mi)
- Metropolis Hotels (87.26 mi)
- Ste Genevieve Hotels (72.81 mi)
- Hazelwood Hotels (87.84 mi)
- Sikeston Hotels (113.94 mi)
- Ozarks Hotels (218.37 mi)
- Fenton Hotels (87.75 mi)
- Alton Hotels (80.38 mi)
Car Rentals Near Southern Illinois
- Car rentals in St. Charles
- Car rentals in Evansville
- Car rentals in Paducah
- Car rentals in Maryland Heights
- Car rentals in Cape Girardeau
- Car rentals in Terre Haute
- Car rentals in Effingham
- Car rentals in Chesterfield
- Car rentals in Marion
- Car rentals in Carbondale
- Car rentals in O'Fallon
- Car rentals in Mount Vernon
- Car rentals in Decatur
- Car rentals in Metropolis
- Car rentals in Ste Genevieve
- Car rentals in Hazelwood
Top Family Hotel Destinations
- Las Vegas Family Hotels
- Arcade Family Hotels
- Branson Family Hotels
- Biloxi Family Hotels
- Ocean City Family Hotels
- Orlando Family Hotels
- Buffalo Family Hotels
- Reno Family Hotels
- Colorado Springs Family Hotels
- Phoenix Family Hotels
- Niagara Falls Family Hotels
- New York Family Hotels
- Whistler Family Hotels
- Houston Family Hotels
- Fort Walton Beach Family Hotels
- Pensacola Beach Family Hotels
- Tampa Family Hotels
- Myrtle Beach Family Hotels
- Miami Beach Family Hotels
- Birmingham Family Hotels
Top Booked Hotels in Southern Illinois
- Super 8 by Wyndham O'Fallon
- Red Lion Inn & Suites Pontoon Beach
- Baymont by Wyndham Marion
- Harrah's Metropolis Hotel & Casino
- Country Inn & Suites by Radisson, Effingham, IL
- Hilton Garden Inn St. Louis Shiloh/O'Fallon IL
- Days Inn by Wyndham Collinsville/St. Louis
- Holiday Inn Express & Suites Edwardsville, an IHG Hotel
- La Quinta Inn & Suites by Wyndham Effingham
- Quality Inn & Suites near St. Louis and I-255