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Featured Luxury Southern Illinois
Super 8 by Wyndham Troy IL/St. Louis Area
910 Edwardsville Rd, Troy, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Troy. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
Rodeway Inn
1400 Thelma Keller Ave, Effingham, IL
Fully refundableReserve now, pay when you stay
Stay at this motel in Effingham. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Suite Dreams Hotel
300 Broadway Avenue East, Mattoon, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Mattoon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Harrah's Metropolis Hotel & Casino
100 E Front St, Metropolis, IL
Stay at this 3.5-star hotel in Metropolis. Enjoy free parking, 2 restaurants, and a casino. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Super 8 by Wyndham Mt. Vernon IL
401 S 44th St, Mount Vernon, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Days Inn by Wyndham Effingham
1602 Damron Court, Effingham, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Super 8 by Wyndham Carbondale
1180 E Main St, Carbondale, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly motel in Carbondale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Holiday Inn Express & Suites Mattoon, an IHG Hotel
121 Swords Dr, Mattoon, IL
Fully refundable
Book a stay at this business-friendly hotel in Mattoon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Quality Inn Effingham
1304 W Evergreen Drive, Effingham, IL
Fully refundableReserve now, pay when you stay
Stay at this hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr, O'Fallon, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Super 8 by Wyndham Fairview Heights-St. Louis
45 Ludwig Dr, Fairview Heights, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our ...
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
6 Gateway Dr, Collinsville, IL
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Collinsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in Southern Illinois
- Hotels with Free Parking in Southern Illinois
- Family Hotels in Southern Illinois
- Pet-friendly Hotels in Southern Illinois
- Hotels with a Pool in Southern Illinois
- Hotels with an Indoor Pool in Southern Illinois
- Hotels with Hot Tubs in Southern Illinois
- Historic Hotels in Southern Illinois
- Resorts & Hotels with Spas in Southern Illinois
- Hotel Wedding Venues in Southern Illinois
- Winery Hotels in Southern Illinois
Top Points of Interests in Southern Illinois
- Hotels near Shawnee National Forest
- Hotels near Harrah's Metropolis
- Hotels near Southern Illinois University
- Hotels near Garden of the Gods Recreation Area
- Hotels near Lake of Egypt
- Hotels near Rend Lake
- Hotels near O'Fallon Family Sports Park
- Hotels near Scott Air Force Base
- Hotels near Giant City State Park
- Hotels near Cahokia Mounds State Historic Site
- Hotels near World Wide Technology Raceway
- Hotels near Carlyle Lake
- Hotels near Gateway Conference Center
- Hotels near DuQuoin State Fairgrounds
- Hotels near St. Claire Square Mall
- Hotels near Marion Cultural and Civic Center
- Hotels near McKendree University
- Hotels near National Shrine of Our Lady of the Snows
- Hotels near St. Clair Bowl
- Hotels near Lake Sara
Cities near Southern Illinois
- St. Charles Hotels (93.9 mi)
- Evansville Hotels (74.5 mi)
- Paducah Hotels (92.61 mi)
- Maryland Heights Hotels (89.1 mi)
- Terre Haute Hotels (104.99 mi)
- Effingham Hotels (51.13 mi)
- Cape Girardeau Hotels (85.27 mi)
- Chesterfield Hotels (95.5 mi)
- Marion Hotels (47.47 mi)
- O'Fallon Hotels (59.98 mi)
- Mount Vernon Hotels (7.84 mi)
- Carbondale Hotels (51.91 mi)
- Ste Genevieve Hotels (72.81 mi)
- Hazelwood Hotels (87.84 mi)
- Decatur Hotels (98.88 mi)
- Bridgeton Hotels (89.05 mi)
- Sikeston Hotels (113.94 mi)
- Fairview Heights Hotels (65.38 mi)
- Farmington Hotels (97.13 mi)
- Collinsville Hotels (65.17 mi)
Car Rentals Near Southern Illinois
- Car rentals in St. Charles
- Car rentals in Evansville
- Car rentals in Paducah
- Car rentals in Maryland Heights
- Car rentals in Terre Haute
- Car rentals in Effingham
- Car rentals in Cape Girardeau
- Car rentals in Chesterfield
- Car rentals in Marion
- Car rentals in O'Fallon
- Car rentals in Mount Vernon
- Car rentals in Carbondale
- Car rentals in Ste Genevieve
- Car rentals in Hazelwood
- Car rentals in Decatur
- Car rentals in Bridgeton
Top Luxury Hotel Destinations
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- South Padre Island Luxury Hotels
- Cheyenne Luxury Hotels
- Corpus Christi Luxury Hotels
- Gettysburg Luxury Hotels
- Fresno Luxury Hotels
- Fayetteville Luxury Hotels
- Springfield Luxury Hotels
- Flagstaff Luxury Hotels
- Tuscaloosa Luxury Hotels
- Toledo Luxury Hotels
- Traverse City Luxury Hotels
- Twin Falls Luxury Hotels
- Scranton Luxury Hotels
- Columbia Luxury Hotels
- Catalina Island Luxury Hotels
- Shreveport Luxury Hotels
- Tallahassee Luxury Hotels