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Featured Luxury St. Charles
Ameristar Casino Resort and Spa
1 Ameristar Blvd, St. Charles, MO
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms and the property ...
Country Inn & Suites by Radisson, St. Charles Historic District
1190 S Main St, St. Charles, MO
Fully refundable
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Red Roof Inn St Louis - St Charles
2010 Zumbehl Road, St. Charles, MO
Book a stay at this business-friendly hotel in St. Charles. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Ameristar Casino St. ...
Relax Inn Saint Charles
3800 Harry S Truman Blvd, St. Charles, MO
Fully refundable
Stay at this motel in St. Charles. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the clean rooms in our reviews. Popular attractions ...
Baymont by Wyndham St. Charles
801 Veterans Memorial Parkway, St. Charles, MO
Fully refundableReserve now, pay when you stay
Stay at this hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Embassy Suites by Hilton St. Louis St. Charles
2 Convention Center Plz, St. Charles, MO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in St. Charles. Enjoy free breakfast, free parking, and a free area shuttle. Our guests praise the breakfast and ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
More Hotel Options in St. Charles
- Historic Hotels in St. Charles
- Casinos in St. Charles
- Hotels with Free Parking in St. Charles
- Family Hotels in St. Charles
- Hotels with a Pool in St. Charles
- Hotels with an Indoor Pool in St. Charles
- Pet-friendly Hotels in St. Charles
- Hotel Wedding Venues in St. Charles
- Hotels with Hot Tubs in St. Charles
- Romantic Hotels in St. Charles
St. Charles Neighborhoods
Top Points of Interests in St. Charles
- Hotels near Ameristar Casino St. Charles
- Hotels near St Charles Convention Center
- Hotels near Historic Main Street
- Hotels near Family Arena
- Hotels near Lindenwood University
- Hotels near Katy Trail
- Hotels near Fast Lane Classic Cars
- Hotels near Lewis & Clark Boathouse and Nature Center
- Hotels near Missouri Bluffs Golf Course
- Hotels near First Missouri State Capitol Historic Site
- Hotels near Weldon Spring Site Interpretive Center
- Hotels near Jaycee Park
- Hotels near St. Louis Union Station
- Hotels near Gateway Arch
- Hotels near Enterprise Center
- Hotels near St. Louis Zoo
- Hotels near Busch Stadium
- Hotels near Washington University in St. Louis
- Hotels near Dome at America’s Center
- Hotels near City Museum
Cities near St. Charles
- Maryland Heights Hotels (6.33 mi)
- Chesterfield Hotels (9.49 mi)
- Hazelwood Hotels (6.19 mi)
- Bridgeton Hotels (4.85 mi)
- St. Peters Hotels (6.7 mi)
- O'Fallon Hotels (11 mi)
- St. Ann Hotels (7.05 mi)
- Wentzville Hotels (19.2 mi)
- Collinsville Hotels (28.73 mi)
- Fenton Hotels (19.25 mi)
- Innsbrook Hotels (29.82 mi)
- Edwardsville Hotels (27.79 mi)
- Alton Hotels (18.27 mi)
- Ozarks Hotels (156.82 mi)
- Kirkwood Hotels (14.96 mi)
- Arnold Hotels (25.37 mi)
- Richmond Heights Hotels (14.6 mi)
- Wildwood Hotels (15.65 mi)
- Eureka Hotels (20.94 mi)
- Brentwood Hotels (14.23 mi)
Car Rentals Near St. Charles
- Car rentals in Maryland Heights
- Car rentals in Chesterfield
- Car rentals in Hazelwood
- Car rentals in Bridgeton
- Car rentals in St. Peters
- Car rentals in O'Fallon
- Car rentals in St. Ann
- Car rentals in Wentzville
- Car rentals in Collinsville
- Car rentals in Fenton
- Car rentals in Innsbrook
- Car rentals in Edwardsville
- Car rentals in Alton
- Car rentals in Ozarks
- Car rentals in Kirkwood
- Car rentals in Arnold
Top Luxury Hotel Destinations
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- Fayetteville Luxury Hotels
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- Flagstaff Luxury Hotels
- Tuscaloosa Luxury Hotels
- Toledo Luxury Hotels
- Traverse City Luxury Hotels
- Twin Falls Luxury Hotels
- Scranton Luxury Hotels
- Columbia Luxury Hotels
- Catalina Island Luxury Hotels
- Shreveport Luxury Hotels
- Tallahassee Luxury Hotels
Top Booked Hotels in St. Charles
- Ameristar Casino Resort and Spa
- Embassy Suites by Hilton St. Louis St. Charles
- Country Inn & Suites by Radisson, St. Charles Historic District
- Country Inn & Suites by Radisson, St. Peters, MO
- Hyatt Regency St. Louis at The Arch
- Hollywood Casino & Hotel St. Louis
- Clayton Plaza Hotel & Extended Stay
- The Last Hotel
- Renaissance St. Louis Airport Hotel