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Hotels in Isla Santa María

Choose from 195 Isla Santa María Hotel Deals

Hotel Fiesta
Hotel Fiesta
3.5 out of 5
Calle Moises Brito y Juan Montalvo, Puerto Ayora, Galapagos
  • 1 hour drive from Post Office Bay
Stay at this 3.5-star hotel in Puerto Ayora. Enjoy free WiFi, 3 hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (331 reviews)
"A beautiful oasis to spend our time on Santa Cruz! It was a great location. The grounds were beautiful and we had a wonderful breakfast every morning to start our day. The staff were all extremely friendly and helpful. We highly recommend Hotel Fiesta!"

Reviewed on Jun 10, 2025

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Hotel Fiesta
Hotel el descanso del Guia
Hotel el descanso del Guia
3.5 out of 5
Calle Delfin, Barrio el Mirador, Puerto Ayora, Galapagos
  • 1 hour drive from Post Office Bay
Stay at this 3.5-star family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our ...
8.6/10 Excellent! (151 reviews)
"Spotlessly clean. Hairdryer in bathroom comfortable bed. Breakfast was excellent. Nice swimming pool. Cab ride into town $2 or a half hour walk."

Reviewed on Jun 10, 2025

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Hotel el descanso del Guia
El Barranco Galapagos
El Barranco Galapagos
3 out of 5
Los colonos, Puerto Ayora, Galapagos
  • 1 hour drive from Post Office Bay
Stay at this 3-star hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and room service. Popular attractions Malecon and Gus Angermeyer Ferry Terminal are ...
9.2/10 Wonderful! (5 reviews)
"Amazing location overlooking the bay. We saw sea turtles, reef sharks, sea lions and lots of fish just sitting at the bar sipping cocktails. Breakfast is at the sister hotel across the road. The food served is from 2pm-10pm only (and also comes from across the street) and is cash only but very delicious ..."

Reviewed on Jun 10, 2025

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El Barranco Galapagos
Blu Galapagos Sustainable Waterfront Lodge
Blu Galapagos Sustainable Waterfront Lodge
4 out of 5
Ave. Charles Darwin S/n Y Piquero, Puerto Ayora, Galapagos
  • 1 hour drive from Post Office Bay
Stay at this 4-star business-friendly hotel in Puerto Ayora. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in ...
8.6/10 Excellent! (112 reviews)
"Wonderful hotel. Our room was incredible. We stayed in Darwin. But there was no hot water for 2/3 of our stay. All we were able to get out of them was a free breakfast one day. I would have expected a significant discount given this lacking amenity"

Reviewed on May 27, 2025

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Blu Galapagos Sustainable Waterfront Lodge
Hotel Cucuve
Hotel Cucuve
4 out of 5
Charles Binford 083 y Ave Charles Darwin, Puerto Ayora
  • 1 hour drive from Post Office Bay
Stay at this 4-star B&B in Puerto Ayora. Enjoy free breakfast, free WiFi, and an airport shuttle (surcharge). Our guests praise the breakfast and the helpful ...
9.8/10 Exceptional! (250 reviews)
"Great service, friendly staff, comfy bed, delicious breakfast, close to town center….helpful Ana…. Excellent stay"

Reviewed on Jun 8, 2025

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Hotel Cucuve
Finch Bay Galapagos Hotel
Finch Bay Galapagos Hotel
4.5 out of 5
Barrio Punta Estrada, Puerto Ayora, Galapagos
  • 1 hour drive from Post Office Bay
Stay at this 4.5-star luxury hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a full-service spa. Popular attractions Playa de los Alemanes and Malecon ...
9.2/10 Wonderful! (85 reviews)
"Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!"

Reviewed on Dec 31, 2024

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Finch Bay Galapagos Hotel
Galapagos Dreams
Galapagos Dreams
3 out of 5
Av. Cucuve y Floreana, Puerto Ayora, Santa Cruz
  • 1 hour drive from Post Office Bay
Stay at this 3-star hostal in Puerto Ayora. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (120 reviews)
Family Trip 2025
"We had a wonderful stay at this hotel. The location was perfect, making it easy to explore the area. The staff were exceptionally friendly and helpful, always ready to assist with any questions or requests. The service was top-notch, and they made us feel welcome throughout our stay. For a fee, they ..."

Reviewed on Mar 24, 2025

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Galapagos Dreams
Capitan Max B&B
Capitan Max B&B
3 out of 5
Charles Binford St, Puerto Ayora, Galapagos
  • 1 hour drive from Post Office Bay
Stay at this 3-star business-friendly B&B in Puerto Ayora. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (167 reviews)
Must stay in Peurto Ayora
"Excellent hosts and great place that feels like home."

Reviewed on Jun 12, 2025

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Capitan Max B&B
Angermeyer Waterfront Inn
Angermeyer Waterfront Inn
3.5 out of 5
Punta Estrada, Isla Santa Cruz, Puerto Ayora, Galapagos
  • 1 hour drive from Post Office Bay
Stay at this 3.5-star hotel in Puerto Ayora. Enjoy free WiFi, a marina, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (115 reviews)
"Excellent - great ambiance with waterfront and bungalow rooms and foliage on the ground . Very accommodating and friendly staff and water taxi was convenient to have an oasis within reach of the town"

Reviewed on May 30, 2025

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Angermeyer Waterfront Inn
Ikala Galapagos Hotel
Ikala Galapagos Hotel
4 out of 5
Tomas de Berlanga 110 y Moises Brito, Puerto Ayora, Ecuador
  • 1 hour drive from Post Office Bay
Stay at this 4-star business-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff and ...
9.6/10 Exceptional! (109 reviews)
"Beds too hard"

Reviewed on May 28, 2025

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Ikala Galapagos Hotel
Posada del Mar
Posada del Mar
3 out of 5
Thomas de Berlanga 217 y Av. Baltra, Puerto Ayora, Islas Galápagos
  • 1 hour drive from Post Office Bay
Stay at this 3-star hotel in Puerto Ayora. Enjoy breakfast (surcharge), daily housekeeping, and dry cleaning or laundry services. Our guests praise the helpful ...
9.6/10 Exceptional! (182 reviews)
"Great value for location."

Reviewed on Jun 1, 2025

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Posada del Mar
Maidith Galapagos Inn
Maidith Galapagos Inn
3 out of 5
Calle Cucuve #341 y Seymour, Santa Cruz, Puerto Ayora, Galápagos
  • 1 hour drive from Post Office Bay
Stay at this 3-star family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the breakfast and the helpful ...
9.8/10 Exceptional! (84 reviews)
"A family run business that goes above and beyond to care for their guests. A beautiful hotel able to get to know and give individual attention."

Reviewed on Jun 11, 2025

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Maidith Galapagos Inn
See all 195 properties in Isla Santa María
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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