Search Deals on
James Island Vacation Packages

Build your package with 2 more options

Leaving from

Going to

Departing

Returning

Travelers

Room 1

Adults

ChildrenAges 2 to 17

InfantsYounger than 2

Add specific hotel dates

A lush green rice paddy field with a tree in the foreground.

James Island
Charleston
South Carolina
United States of America
North America
Hotwire.com

James Island Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Hotel Indigo Mount Pleasant by IHG

3.5 out of 5

Price was $819, price is now $641 per person

$641

per person

Oct 24 - Oct 29

found 1 day ago

Roundtrip flight included

Boston (BOS) to Charleston (CHS)

Book a stay at this business-friendly hotel in Mount Pleasant. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the helpful staff in our reviews. Popular attractions Patriots Point and Shem Creek Park are located nearby.

The Ryder Hotel

3.5 out of 5

Save 100% on your flight

Price was $1,560, price is now $993 per person

$993

per person

Sep 24 - Sep 28

found 1 day ago

Roundtrip flight included

Boston (BOS) to Charleston (CHS)

Stay at this hotel in Charleston. Enjoy 2 bars/lounges, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Charleston City Market and Waterfront Park are located nearby.

Planters Inn

4.5 out of 5

Save 100% on your flight

Price was $2,226, price is now $1,588 per person

$1,588

per person

Sep 24 - Sep 28

found 1 day ago

Roundtrip flight included

Boston (BOS) to Charleston (CHS)

Book a stay at this luxury hotel in Charleston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Charleston City Market and Waterfront Park are located nearby.

Great location! Very clean! Friendly staff! Beautiful room

Reviewed on Aug 22, 2026

Emeline

4 out of 5

Save 100% on your flight

Price was $1,613, price is now $1,226 per person

$1,226

per person

Oct 21 - Oct 24

found 1 day ago

Roundtrip flight included

Boston (BOS) to Charleston (CHS)

Book a stay at this luxury hotel in Charleston. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions Charleston City Market and Waterfront Park are located nearby.

Great location , spacious rooms

Reviewed on Aug 23, 2026

The Charleston Place

5 out of 5

Save 100% on your flight

Price was $2,123, price is now $1,648 per person

$1,648

per person

Oct 21 - Oct 24

found 1 day ago

Roundtrip flight included

Boston (BOS) to Charleston (CHS)

Book a stay at this luxury hotel in Charleston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Charleston City Market and Waterfront Park are located nearby.

Absolute five-star experience. Everything is impeccable, from the room to the dining to the staff. Perfect location in a beautiful city.

Reviewed on Aug 23, 2026

The Ansonborough

4 out of 5

Save 100% on your flight

Price was $1,458, price is now $1,133 per person

$1,133

per person

Sep 24 - Sep 28

found 1 day ago

Roundtrip flight included

Boston (BOS) to Charleston (CHS)

Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Charleston City Market and Waterfront Park are located nearby.

Andrew Pinckney Inn

4 out of 5

Price was $1,483, price is now $1,157 per person

$1,157

per person

Oct 25 - Oct 30

found 1 day ago

Roundtrip flight included

Boston (BOS) to Charleston (CHS)

Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and valet parking (surcharge). Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Charleston City Market and Waterfront Park are located nearby.

The Palmetto Hotel

4 out of 5

Save 100% on your flight

Price was $1,720, price is now $1,342 per person

$1,342

per person

Oct 24 - Oct 29

found 1 day ago

Roundtrip flight included

Boston (BOS) to Charleston (CHS)

Stay at this hotel in Charleston. Enjoy free breakfast, free WiFi, and free bicycles on site. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Waterfront Park and Charleston City Market are located nearby.