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Main Street Vacation Packages

Main Street Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Sonesta ES Suites San Antonio Northwest - Medical Center

Sonesta ES Suites San Antonio Northwest - Medical Center

3 out of 5
per person
Apr 8 - Apr 13
found 1 day ago
Roundtrip flight included
Detroit (DTW) to San Antonio (SAT)
Stay at this 3-star hotel in San Antonio. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Six Flags Fiesta Texas and North Star Mall are located nearby.
Club Wyndham La Cascada

Club Wyndham La Cascada

4 out of 5
Save 100% on your flight
per person
Apr 19 - Apr 23
found 22 hours ago
Roundtrip non-stop flight included
Philadelphia (PHL) to San Antonio (SAT)
Stay at this 4-star hotel in San Antonio. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions San Antonio River and River Walk are located nearby.
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

3.5 out of 5
per person
Apr 8 - Apr 13
found 1 day ago
Roundtrip flight included
Detroit (DTW) to San Antonio (SAT)
Stay at this 3.5-star family-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and a lazy river. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Hill Country Golf Club and Aquatica San Antonio Waterpark are located nearby.
Hotel Contessa

Hotel Contessa

4 out of 5
per person
Apr 8 - Apr 13
found 1 day ago
Roundtrip flight included
Detroit (DTW) to San Antonio (SAT)
Stay at this 4-star spa hotel in San Antonio. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the pool in our reviews. Popular attractions River Walk and San Antonio River are located nearby.
Holiday Inn Express & Suites San Antonio Medical-Six Flags, an IHG Hotel

Holiday Inn Express & Suites San Antonio Medical-Six Flags, an IHG Hotel

2.5 out of 5
per person
Apr 8 - Apr 13
found 1 day ago
Roundtrip flight included
Detroit (DTW) to San Antonio (SAT)
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Six Flags Fiesta Texas and The Shops of La Cantera are located nearby.
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
per person
Apr 8 - Apr 13
found 1 day ago
Roundtrip flight included
Detroit (DTW) to San Antonio (SAT)
Stay at this 4-star family-friendly hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the bar in our reviews. Popular attractions San Antonio River and River Walk are located nearby.
Hilton San Antonio Hill Country

Hilton San Antonio Hill Country

4 out of 5
per person
Apr 8 - Apr 13
found 1 day ago
Roundtrip flight included
Detroit (DTW) to San Antonio (SAT)
Stay at this 4-star family-friendly hotel in San Antonio. Enjoy free WiFi, 3 outdoor pools, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Hill Country Golf Club and Aquatica San Antonio Waterpark are located nearby.
Canopy by Hilton San Antonio Riverwalk

Canopy by Hilton San Antonio Riverwalk

4 out of 5
per person
Apr 8 - Apr 13
found 1 day ago
Roundtrip flight included
Detroit (DTW) to San Antonio (SAT)
Stay at this 4-star business-friendly hotel in San Antonio. Enjoy breakfast (surcharge), a 24-hour fitness center, and valet parking (surcharge). Our guests praise the restaurant and the bar in our reviews. Popular attractions River Walk and San Antonio River are located nearby.
Crockett Hotel

Crockett Hotel

3 out of 5
per person
Apr 8 - Apr 13
found 1 day ago
Roundtrip flight included
Detroit (DTW) to San Antonio (SAT)
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, valet parking (surcharge), and a 24-hour front desk. Our guests praise the pool and the restaurant in our reviews. Popular attractions River Walk and Alamo are located nearby.
Home2 Suites by Hilton San Antonio Riverwalk, TX

Home2 Suites by Hilton San Antonio Riverwalk, TX

3 out of 5
per person
Apr 8 - Apr 13
found 1 day ago
Roundtrip flight included
Detroit (DTW) to San Antonio (SAT)
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool in our reviews. Popular attractions San Antonio River and River Walk are located nearby.
Holiday Inn San Antonio N - Stone Oak Area, an IHG Hotel

Holiday Inn San Antonio N - Stone Oak Area, an IHG Hotel

3 out of 5
per person
Apr 8 - Apr 13
found 1 day ago
Roundtrip flight included
Detroit (DTW) to San Antonio (SAT)
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Ice & Golf Center at Northwoods and Saddle Mountain Park are located nearby.

3-4 Night Vacations in Main Street

Price found within the past 48 hours. Click for updated prices.
Bluegreen Vacations Eilan Hotel and Spa, Ascend Resort Collection

Bluegreen Vacations Eilan Hotel and Spa, Ascend Resort Collection

4.5 out of 5
La Cantera District
per person
Apr 10 - Apr 13
found 16 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to San Antonio (SAT)
La Quinta Inn and Suites by Wyndham Schertz-San Antonio-Selma

La Quinta Inn and Suites by Wyndham Schertz-San Antonio-Selma

2.5 out of 5
per person
Apr 3 - Apr 7
found 23 hours ago
Roundtrip non-stop flight included
Knoxville (TYS) to San Antonio (SAT)
The William Boerne Hotel

The William Boerne Hotel

2.5 out of 5
Save 100% on your flight
per person
Apr 4 - Apr 7
found 16 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to San Antonio (SAT)
Tapatio Springs Hill Country Resort

Tapatio Springs Hill Country Resort

4 out of 5
per person
Apr 4 - Apr 7
found 16 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to San Antonio (SAT)

5-7 Night Vacations in Main Street

Price found within the past 48 hours. Click for updated prices.
Holiday Inn Express & Suites San Antonio Medical-Six Flags, an IHG Hotel

Holiday Inn Express & Suites San Antonio Medical-Six Flags, an IHG Hotel

2.5 out of 5
Northwest Side
per person
Apr 8 - Apr 13
found 1 day ago
Roundtrip flight included
Detroit (DTW) to San Antonio (SAT)
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

3.5 out of 5
Far West Side
per person
Apr 8 - Apr 13
found 1 day ago
Roundtrip flight included
Detroit (DTW) to San Antonio (SAT)
Hotel Contessa

Hotel Contessa

4 out of 5
Downtown San Antonio
per person
Apr 8 - Apr 13
found 1 day ago
Roundtrip flight included
Detroit (DTW) to San Antonio (SAT)

Main Street Last Minute Hotel Deals

The Dilworth Inn
The Dilworth Inn
3 out of 5
603 North Saint Joseph Street, Gonzales, TX
Stay at this 3-star hotel in Gonzales. Enjoy free WiFi, free parking, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular attractions ...
The Dilworth Inn
The Alcalde Hotel
The Alcalde Hotel
2 out of 5
614 St Paul St, Gonzales, TX
Stay at this hotel in Gonzales. Enjoy free WiFi, free parking, and housekeeping. Popular attractions Confederate Square and Discoveries From the Past are located ...
The Alcalde Hotel
Sonesta Essential Gonzales
Sonesta Essential Gonzales
2.5 out of 5
2019 Water Street, Gonzales, TX
Book a stay at this business-friendly hotel in Gonzales. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Sonesta Essential Gonzales
Belle Oaks Inn
Belle Oaks Inn
3 out of 5
222 St. Peter Street, Gonzales, TX
Stay at this 3-star B&B in Gonzales. Enjoy free breakfast, free WiFi, and free parking. Popular attractions First Baptist Church and Texas Heroes Square are ...
Belle Oaks Inn
Quality Inn
Quality Inn
2.5 out of 5
1804 E. Sarah Dewitt Drive, Gonzales, TX
Stay at this hotel in Gonzales. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Gonzales Memorial Museum and Discoveries From the Past ...
Quality Inn
La Quinta Inn & Suites by Wyndham Gonzales TX
La Quinta Inn & Suites by Wyndham Gonzales TX
2.5 out of 5
1631 Water St., Gonzales, TX
Book a stay at this business-friendly hotel in Gonzales. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
La Quinta Inn & Suites by Wyndham Gonzales TX
Studio 6 Gonzales, TX
Studio 6 Gonzales, TX
2 out of 5
2131 Water St, Gonzales, TX
Book a stay at this business-friendly hotel in Gonzales. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Discoveries From the Past ...
Studio 6 Gonzales, TX
Holiday Inn Express & Suites Gonzales, an IHG Hotel
Holiday Inn Express & Suites Gonzales, an IHG Hotel
2.5 out of 5
126 Middle Buster Road, Gonzales, TX
Book a stay at this business-friendly hotel in Gonzales. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Discoveries From the Past and ...
Holiday Inn Express & Suites Gonzales, an IHG Hotel
See all 439 properties in Main Street
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.