Search Deals onMain Street Hyannis Vacation Packages
Main Street Hyannis Flight + Hotel Packages
Price found within the past 48 hours. Click for updated prices.

Sonesta Select Boston Milford
per person
Sep 24 - Sep 28
found 23 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Boston (BOS)
Stay at this 3-star business-friendly hotel in Milford. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Vietnam Mountain Biking Trail and The Tasting Room - An Italian Wine Shop are located nearby.

Raffles Boston
Save 100% on your flight
per person
Oct 3 - Oct 7
found 19 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Boston (BOS)
Stay at this 5-star luxury hotel in Boston. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions Copley Square and Boston Common are located nearby.

Boston Harbor Hotel
Save 100% on your flight
per person
Oct 3 - Oct 7
found 19 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Boston (BOS)
Stay at this 5-star luxury hotel in Boston. Enjoy free WiFi, a marina, and breakfast (surcharge). Our guests praise the helpful staff and the room service in our reviews. Popular attractions New England Aquarium and Faneuil Hall Marketplace are located nearby.

Sonesta Select Boston Danvers
Save 100% on your flight
per person
Oct 9 - Oct 14
found 19 hours ago
Roundtrip flight included
Detroit (DTW) to Boston (BOS)
Stay at this 3-star business-friendly hotel in Danvers. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Salem Witch Museum and Rebecca Nurse Homestead are located nearby.

Harbor Hotel Provincetown
Save 100% on your flight
per person
Sep 26 - Oct 4
found 20 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Provincetown (PVC)
Book a stay at this beach hotel in Provincetown. Enjoy free parking, an outdoor pool, and a beach locale. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Commercial Street and Town Beach are located nearby.

The Charles Hotel
Save 100% on your flight
per person
Sep 29 - Oct 6
found 12 hours ago
Roundtrip flight included
Atlanta (ATL) to Boston (BOS)
Stay at this 4-star luxury hotel in Cambridge. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions Harvard Square and Fenway Park are located nearby.

Rockport Inn And Suites
Save 100% on your flight
per person
Oct 9 - Oct 14
found 19 hours ago
Roundtrip flight included
Detroit (DTW) to Boston (BOS)
Stay at this B&B in Rockport. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Cape Ann and Good Harbor Beach are located nearby.

DoubleTree by Hilton Boston North Shore
per person
Sep 18 - Sep 24
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Boston (BOS)
Stay at this 4-star golf hotel in Danvers. Enjoy free parking, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Water Park of New England and Glen Magna Farms are located nearby.

DoubleTree Suites by Hilton Hotel Boston - Cambridge
Save 100% on your flight
per person
Sep 24 - Sep 29
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Boston (BOS)
Book a stay at this business-friendly hotel in Boston. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Harvard Square and Fenway Park are located nearby.

Global Luxury Suites Downtown Boston
Save 100% on your flight
per person
Sep 26 - Oct 1
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Boston (BOS)
Stay at this 4-star business-friendly aparthotel in Boston. Enjoy free WiFi, a 24-hour front desk, and a 24-hour business center. Our guests praise the helpful staff in our reviews. Popular attractions Boston Common and Faneuil Hall Marketplace are located nearby.

The Boston Hotel
Save 100% on your flight
per person
Oct 6 - Oct 11
found 1 day ago
Roundtrip flight included
Detroit (DTW) to Boston (BOS)
Book a stay at this business-friendly hotel in Boston. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Fenway Park and Harvard Square are located nearby.

The Provincetown Inn
Save 100% on your flight
per person
Sep 26 - Oct 4
found 21 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Provincetown (PVC)
Stay at this 3-star beach hotel in Provincetown. Enjoy an outdoor pool, 3 restaurants, and a beach locale. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Commercial Street and Pilgrims' First Landing Park are located nearby.
3-4 Night Vacations in Main Street Hyannis
Price found within the past 48 hours. Click for updated prices.



5-7 Night Vacations in Main Street Hyannis
Price found within the past 48 hours. Click for updated prices.



Main Street Hyannis Last Minute Hotel Deals

Hyannis Plaza Hotel
662 Main Street, Hyannis, MA
Book a stay at this luxury hotel in Hyannis. Enjoy free parking, an outdoor pool, and a 24-hour front desk. Popular attractions Hyannis Harbor and Cape Codder ...

Comfort Inn Hyannis - Cape Cod
259 Main Street, Hyannis, MA
Book a stay at this business-friendly hotel in Hyannis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Heritage House Inn on Cape Cod
540 Old Colony Rd, Hyannis, MA
Stay at this motel in Hyannis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Hyannis ...

Hyannis Inn
473 MAIN ST, Hyannis, MA
Stay at this motel in Hyannis. Enjoy free WiFi, free parking, and a garden. Our guests praise the pool and the helpful staff in our reviews. Popular attractions ...

Hyannis Harbor Hotel
213 Ocean St, Hyannis, MA
Stay at this 3.5-star business-friendly hotel in Hyannis. Enjoy free WiFi, an outdoor pool, and parking (surcharge). Our guests praise the helpful staff in our ...

Cape Cod Inn
447 Main St, Hyannis, MA
Stay at this motel in Hyannis. Enjoy free WiFi, free parking, and daily housekeeping. Our guests praise the helpful staff and the clean rooms in our reviews. ...

Americas Best Value Inn & Suites Hyannis Cape Cod
206 Main St, Hyannis, MA
Stay at this hotel in Hyannis. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the clean rooms and the overall value in our reviews. Popular ...

Anchor In Distinctive Waterfront Lodging
1 South Street, Hyannis, MA
Stay at this 3-star hotel in Hyannis. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover Other Travel Deals
- Legoland Florida
- Universal Studios Hollywood®
- Legoland California
- Broadway New York
- The Wizarding World of Harry Potter
- Sanibel Captiva Island
- Paseo de España
- Universal Studios Florida
- San Antonio SeaWorld
- Siargao Island
- Australia Zoo
- Busch Gardens Tampa Bay
- SeaWorld® Orlando
- Tolantongo Caves
- Eleuthera and Harbour Island
- Biltmore Estate
- Blue Lagoon
- Swiss Alps
- Silver Dollar City
- Lackland Air Force Base
- Grand Teton National Park
- San Diego Zoo
- Holy Land Experience
- Grand Ole Opry
- Ark Encounter
- Levi's Stadium
- Breckenridge Ski Resort
- Alcatraz Island
- Six Flags Magic Mountain
- Walt Disney World®
- Dollywood
- Kalahari Waterpark Resort
- Giza Pyramid Complex
- Casino at Don Laughlin's Riverside Resort
- Hoover Dam
- Hollywood Beach
- Faisalabad Clock Tower
- Venice Beach Boardwalk
- Blue Lagoon Beach
- Moraine Lake
Hotels Near Points of Interest in Main Street Hyannis
- Hotels near John F. Kennedy Hyannis Museum
- Hotels near Hyannis Harbor
- Hotels near Mayflower Beach
- Hotels near Cape Cod Inflatable Park
- Hotels near Cape Cod Melody Tent
- Hotels near Harwich Port
- Hotels near Craigville Beach
- Hotels near West Dennis Beach
- Hotels near Cape Cod Rail Trail
- Hotels near Seagull Beach
- Hotels near Sandy Neck Beach
- Hotels near Kalmus Beach
- Hotels near Corporation Beach
- Hotels near Sea Street Beach
- Hotels near Barnstable Harbor
- Hotels near Grays Beach
Car Rentals in Main Street Hyannis
- Car rentals in Cape Cod
- Car rentals in Martha's Vineyard
- Car rentals in Hyannis
- Car rentals in Chatham
- Car rentals in Falmouth
- Car rentals in South Yarmouth
- Car rentals in Oak Bluffs
- Car rentals in Edgartown
- Car rentals in Plymouth
- Car rentals in Sandwich
- Car rentals in West Yarmouth
- Car rentals in Dennis Port
- Car rentals in Brewster
- Car rentals in Wellfleet
- Car rentals in Dennis
- Car rentals in Eastham